{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:30:14Z","timestamp":1777523414444,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2008,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To quantify comparative improvement between osseous and soft tissue asymmetry following primary lip repair.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Retrospective analysis of preoperative and postoperative computed tomography scans of infants with unilateral cleft lip and palate. Sixteen soft tissue landmarks were placed using an exploratory two-\/three-dimensional image processing system and compared for asymmetry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients:<\/jats:title>\n                    <jats:p>Computed tomography scans were obtained on 26 patients (13 boys, 13 girls) of Chinese ethnicity (mean age \u200a=\u200a 0.25 years) prior to Millard lip repair. Nineteen of these contributed to follow-up comparative studies prior to palatoplasty at a mean age of 0.92 years. There were 18 left-sided and eight right-sided clefts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measure:<\/jats:title>\n                    <jats:p>Euclidean distance matrix asymmetry analysis was used to determine the amount of soft tissue asymmetry pre- and postlip repair. Similar analyses of the same scans were performed for 41 osseous landmarks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Soft tissue landmarks had 36\/39 (92%) preoperative and 13\/39 (33%) postoperative asymmetric pairs. Osseous distances demonstrated 77\/125 (61%) asymmetric pairs preoperatively and 60\/125 (48%) postoperatively. Soft tissue and osseous distances of the lip region demonstrated 32% and 39% postoperative asymmetry, respectively. Soft tissue and osseous distances of the nasal region demonstrated 52% and 72% postoperative asymmetry, respectively. Soft tissue and osseous distances of the facial landmarks demonstrated 24% and 34% postoperative asymmetry, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Primary lip repair appears to effect gains in symmetry in soft tissue and provides sufficient molding forces to cause correlating symmetry changes in underlying osseous structures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1597\/07-001.1","type":"journal-article","created":{"date-parts":[[2008,9,12]],"date-time":"2008-09-12T19:02:12Z","timestamp":1221246132000},"page":"511-517","source":"Crossref","is-referenced-by-count":12,"title":["Comparative Osseous and Soft Tissue Morphology following Cleft Lip Repair"],"prefix":"10.1177","volume":"45","author":[{"given":"Lynn M.","family":"Seidenstricker-Kink","sequence":"first","affiliation":[{"name":"University of Tennessee, Memphis, Tennessee."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devra B.","family":"Becker","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine, St. Louis, Missouri."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel P.","family":"Govier","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine, St. Louis, Missouri."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie B.","family":"DeLeon","sequence":"additional","affiliation":[{"name":"Center for Functional Anatomy & Evolution, Johns Hopkins University School of Medicine, Baltimore, Maryland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lun-Jou","family":"Lo","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex A.","family":"Kane","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine, St. Louis, Missouri."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2008,9,1]]},"reference":[{"key":"bibr1-07-001.1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2003_040_0363_pomaag_2.0.co_2"},{"key":"bibr2-07-001.1","doi-asserted-by":"publisher","DOI":"10.1597\/05-167"},{"key":"bibr3-07-001.1","first-page":"293","volume-title":"Transactions of the 9th International Congress on Cleft Palate and Related Craniofacial Anomalies.","author":"Deleon V.B.","year":"2001"},{"key":"bibr4-07-001.1","first-page":"21","volume-title":"Anthropometry of the Head and Face.","author":"Farkas 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