{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T10:43:26Z","timestamp":1780483406732,"version":"3.54.1"},"reference-count":15,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2009,9]]},"abstract":"\n Objectives:<\/jats:title>\n To investigate the prevalence of upper cervical vertebrae anomalies in patients with isolated cleft lip, isolated cleft palate, and complete cleft lip and palate, as well as to compare the prevalence of these anomalies between groups, between genders, and with noncleft patients.<\/jats:p>\n <\/jats:sec>\n \n Design:<\/jats:title>\n Retrospective cross-sectional study of randomly selected patients.<\/jats:p>\n <\/jats:sec>\n \n Setting:<\/jats:title>\n Radiology Section, Hospital for Rehabilitation of Craniofacial Anomalies and Department of Orthodontics, Bauru School of Dentistry, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil.<\/jats:p>\n <\/jats:sec>\n \n Participants:<\/jats:title>\n The sample comprised 300 lateral cephalograms of cleft patients, aged 12 to 13 years, of both genders, from the files of the Hospital for Rehabilitation of Craniofacial Anomalies\u2013University of S\u00e3o Paulo and 300 lateral cephalograms from noncleft patients of the Department of Orthodontics, Bauru School of Dentistry. Cephalograms of patients with syndromes were not included.<\/jats:p>\n <\/jats:sec>\n \n Method:<\/jats:title>\n Radiographs were interpreted on a film viewer by a single examiner; the profiles of vertebrae were traced on acetate paper, and cervical vertebrae anomalies were registered and categorized into posterior arch deficiencies, fusion, and association of both.<\/jats:p>\n <\/jats:sec>\n \n Main Outcome Measures:<\/jats:title>\n Statistical comparison of groups using the chi-square test.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n In the cleft group, 38.67% of the patients had cervical vertebrae anomalies. Of those in the noncleft sample, 31% showed anomalies of the cervical spine. This difference was statistically significant. There was no statistically significant difference when the types of clefts were compared with each other or when both genders were compared in both samples.<\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n This study confirms the association between clefts and cervical anomalies. Additional research on this topic is necessary.<\/jats:p>\n <\/jats:sec>","DOI":"10.1597\/08-018.1","type":"journal-article","created":{"date-parts":[[2009,9,2]],"date-time":"2009-09-02T14:33:28Z","timestamp":1251902008000},"page":"481-486","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence of Upper Cervical Vertebrae Anomalies in Patients with Cleft Lip and\/or Palate and Noncleft Patients"],"prefix":"10.1177","volume":"46","author":[{"given":"Marta Cunha","family":"Lima","sequence":"first","affiliation":[{"name":"Department of Orthodontics, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo Jacomino","family":"Franco","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme","family":"Janson","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izabel Maria Marchi","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Dental Radiology Section and Coordinator of Specialization course in Dental Radiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Ferreira","family":"Santos","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, University of S\u00e3o Paulo, Bauru, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana L\u00facia Alvares","family":"Capelozza","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2009,9,1]]},"reference":[{"issue":"2","key":"bibr1-08-018.1","first-page":"267","author":"Diewert V.M.","year":"1986","journal-title":"J Craniofac Genet Dev Biol."},{"key":"bibr2-08-018.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-117X(82)80022-X"},{"key":"bibr3-08-018.1","first-page":"595","volume":"128","author":"Farman A.G.","year":"1979","journal-title":"J Anat."},{"key":"bibr4-08-018.1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.21.1.1397450"},{"key":"bibr5-08-018.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(10)80229-0"},{"key":"bibr6-08-018.1","first-page":"1","volume":"72","author":"Minaba T.","year":"1972","journal-title":"Shikwa Gakuho."},{"key":"bibr7-08-018.1","volume-title":"The Prevalence of Anomalies of the Upper Cervical Vertebrae in Patients With Craniofacial Malformations and Their Effect on Osseous Nasopharyngeal Depth.","author":"Osborne G.S.","year":"1968"},{"key":"bibr8-08-018.1","doi-asserted-by":"publisher","DOI":"10.1044\/jshr.1401.14"},{"key":"bibr9-08-018.1","first-page":"273","volume":"2","author":"Ross R.B.","year":"1965","journal-title":"Cleft Palate J."},{"key":"bibr10-08-018.1","first-page":"206","volume":"23","author":"Sandham A.","year":"1986","journal-title":"Cleft Palate J."},{"key":"bibr11-08-018.1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320200404"},{"key":"bibr12-08-018.1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1993_030_0274_lotcsa_2.3.co_2"},{"key":"bibr13-08-018.1","first-page":"251","volume":"10","author":"Spina V.","year":"1973","journal-title":"Cleft Palate J."},{"key":"bibr14-08-018.1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.103.Supplement.213"},{"key":"bibr15-08-018.1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2001_038_0498_tpoaot_2.0.co_2"}],"container-title":["The Cleft Palate Craniofacial Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1597\/08-018.1","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1597\/08-018.1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:15:57Z","timestamp":1777392957000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1597\/08-018.1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["10.1597\/08-018.1"],"URL":"https:\/\/doi.org\/10.1597\/08-018.1","relation":{},"ISSN":["1055-6656","1545-1569"],"issn-type":[{"value":"1055-6656","type":"print"},{"value":"1545-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9]]}}}