{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T02:55:05Z","timestamp":1790477705003,"version":"4.1.0"},"reference-count":46,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare dental aesthetics and function of orthodontic space closure versus prosthetic replacement of upper lateral incisors in patients with bilateral cleft lip and palate. The predominant mode of prosthetic replacement was resin-bonded bridges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>The retrospective study group consisted of 17 patients treated with orthodontic space closure (13 men, four women; median age, 27.1 years; interquartile range, 20.6 to 33.3 years) and 10 patients treated with prosthetic replacement (five men, five women; median age, 27.7 years; interquartile range, 20.9 to 39.7 years). Dental aesthetics were evaluated by the patients and by a professional panel. Mandibular function was evaluated by means of the mandibular function impairment questionnaire. The level of mandibular impairment was calculated using the Function Impairment Rating Scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>With respect to dental aesthetics, no significant differences between patients treated with orthodontic space closure and prosthetic replacement were found. With respect to function, the level of mandibular impairment was significantly higher in patients treated with prosthetic replacement compared with patients treated with orthodontic space closure, as indicated by high scores on specific masticatory functions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Orthodontic space closure and prosthetic replacement in bilateral cleft lip and palate patients produce similar results in terms of aesthetics. In terms of function, prosthetic replacement results in significantly more impairment of specific masticatory functions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1597\/09-092","type":"journal-article","created":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T17:04:48Z","timestamp":1288631088000},"page":"591-596","source":"Crossref","is-referenced-by-count":23,"title":["Orthodontic Space Closure versus Prosthetic Replacement of Missing Upper Lateral Incisors in Patients with Bilateral Cleft Lip and Palate"],"prefix":"10.1177","volume":"47","author":[{"given":"Barbara Cm.","family":"Oosterkamp","sequence":"first","affiliation":[{"name":"Department of Orthodontics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter U.","family":"Dijkstra","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery and Department of Rehabilitation, School for Health Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hendrik J.","family":"Remmelink","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Cleft Palate Team, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, and private practice, Orthodontics, Almelo, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert P.","family":"Van Oort","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery and Maxillofacial Prosthetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Sandham","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, University Medical Center Groningen, University of 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