{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T02:39:40Z","timestamp":1778899180743,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate possible structural abnormalities of the central auditory pathway in infants with nonsyndromic cleft lip and\/or palate (NSCL\/P).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Twenty-seven Chinese infants with NSCL\/P, aged from 6 to 24 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>Morphological magnetic resonance imaging (MRI) measurements of the central auditory nervous system (CANS) in infants with NSCL\/P were analyzed and compared with those of age- and sex-matched normal controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>No significant group differences were found in general brain measurements, including volumes of the brain stem and right hemisphere. However, infants with NSCL\/P had statistically significantly smaller volumes of the left thalamus and left auditory cortex and notably decreased thickness of the left auditory cortex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Cortical abnormalities were more marked compared with other MRI measurements. Structural CANS abnormalities in infants with NSCL\/P may be located mainly in the left cerebral hemisphere. The development and maturation of the auditory cortex in infants with NSCL\/P may be abnormal when compared with those of normal children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1597\/11-014","type":"journal-article","created":{"date-parts":[[2011,8,17]],"date-time":"2011-08-17T10:09:05Z","timestamp":1313575745000},"page":"137-145","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Structural Abnormalities of the Central Auditory Pathway in Infants with Nonsyndromic Cleft Lip and\/or Palate"],"prefix":"10.1177","volume":"49","author":[{"given":"Frank F.","family":"Yang","sequence":"first","affiliation":[{"name":"University of Hong Kong, Hong Kong, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley","family":"McPherson","sequence":"additional","affiliation":[{"name":"University of Hong Kong, Hong Kong, 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