{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:13:40Z","timestamp":1777522420217,"version":"3.51.4"},"reference-count":40,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe demographic and clinical-genetic characteristics of patients from a poor area of Brazil and to share experience on how the local genetic unit has addressed their major health needs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Descriptive cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>A clinical-genetic unit, a cytogenetics unit, and a regional cleft team located in the northeast and southeast of Brazil.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>A total of 133 individuals with orofacial clefts who attended the surgical call of a nongovernmental organization. From this group, 125, 77, and 13 patients completed phases 1, 2, and 3, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Phase 1 comprised a description of demographic characteristics recorded through interviews. Phase 2 included a clinical-genetic evaluation using a pretested form, as well as cytogenetic analyses of selected patients. Phase 3 comprised collaborative action to address major health needs of patients without primary surgery. The Fisher test was used for statistics with p value &lt; .05.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A majority of patients were rural residents with isolated cleft lip with cleft palate. Ages ranged between 0 and 30 years. Fifty percent had never undergone surgery; whereas, 100% had never attended a genetic evaluation. Isolated cleft was diagnosed in 77.9%, syndromes in 14.3%, and multiple congenital abnormalities in 7.8%. Positive familial history of clefts occurred in 28%; whereas, parental consanguinity was present in 7.8% cases. A total of 23 individuals without cleft surgery were registered for multidisciplinary treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Findings revealed high levels of unmet medical needs and provided an evidence base for health care planning. Collaborative action was crucial and might be applied to other regions in Brazil.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1597\/11-069","type":"journal-article","created":{"date-parts":[[2012,1,11]],"date-time":"2012-01-11T18:33:23Z","timestamp":1326306803000},"page":"424-431","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Local Strategies to Address Health Needs of Individuals with Orofacial Clefts in Alagoas, Brazil"],"prefix":"10.1177","volume":"50","author":[{"given":"Marshall \u00cdtalo Barros","family":"Fontes","sequence":"first","affiliation":[{"name":"Department of Pediatrics, State University of Alagoas, Macei\u00f3, Alagoas, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanusia Nunes","family":"Almeida","sequence":"additional","affiliation":[{"name":"Federal University of Alagoas, Macei\u00f3, Alagoas, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilberto","family":"De Oliveira Reis Junior","sequence":"additional","affiliation":[{"name":"Federal University of Alagoas, Macei\u00f3, Alagoas, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Ivam Vieira","family":"Filho","sequence":"additional","affiliation":[{"name":"Medical Genetics Sector, Federal University of Alagoas, Macei\u00f3, Alagoas, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen Moura Dos","family":"Santos","sequence":"additional","affiliation":[{"name":"Medical Genetics Sector, Federal University of Alagoas, Macei\u00f3, Alagoas, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filipe Silveira Dos","family":"Anjos","sequence":"additional","affiliation":[{"name":"Medical Genetics Sector, Federal University of Alagoas, Macei\u00f3, Alagoas, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Karolina Maia","family":"De Andrade","sequence":"additional","affiliation":[{"name":"Medical Genetics Sector, Federal University of Alagoas, Macei\u00f3, Alagoas, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Guilherme Gaelzer","family":"Porciuncula","sequence":"additional","affiliation":[{"name":"Federal University of Alagoas, Macei\u00f3, Alagoas, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelline Costa","family":"De Oliveira","sequence":"additional","affiliation":[{"name":"Federal University of Alagoas, Macei\u00f3, Alagoas, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui Manoel","family":"Pereira","sequence":"additional","affiliation":[{"name":"Facial Deformity Care Center (CADEFI), Recife, Pernambuco, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarsis Antonio Paiva","family":"Vieira","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, University of Campinas, Campinas, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilma L\u00facia","family":"Viguetti-Campos","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, University of Campinas, Campinas, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera L\u00facia","family":"Gil-Da-Silva-Lopes","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, University of Campinas, Campinas, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella Lopes","family":"Monlle\u00f3","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, State University of Alagoas and Medical Genetics Sector, Federal University of Alagoas, Macei\u00f3, Alagoas, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,7,1]]},"reference":[{"key":"bibr1-11-069","unstructured":"American Cleft Palate\u2013Craniofacial Association. 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