{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:13:00Z","timestamp":1777522380360,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We herewith report the case of a 43-year-old patient who experienced a skull base fracture associated with minimal trauma. The computed tomography scan examination showed unusual extensive pneumatization of the skull base. This patient used to perform repeated Valsalva maneuvers on a daily basis since childhood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A literature search and analysis of pneumatization mechanisms was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Extensive skull base pneumatization has already been reported in patients performing daily Valsalva maneuver. Two pathogenic hypotheses are discussed: the bone cavity expansion through communicating spaces and cavitation secondary to increased intra-osseous pressure transmitted via the venous network with subsequent bone marrow ischemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Valsalva maneuver may be the cause of an extensive skull base pneumatization. We hypothesize that the Valsalva maneuver may induce bone marrow ischemia that may, if repeated and prolonged, lead to pneumatization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1597\/11-280","type":"journal-article","created":{"date-parts":[[2012,3,15]],"date-time":"2012-03-15T20:51:45Z","timestamp":1331844705000},"page":"113-116","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Pneumatization of the Skull Base Due to Valsalva Maneuver"],"prefix":"10.1177","volume":"50","author":[{"given":"Alexis","family":"Lacout","sequence":"first","affiliation":[{"name":"Centre d'imagerie M\u00e9dicale, 47, Boulevard du Pont Rouge, 15000 Aurillac, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Yves Marcy","sequence":"additional","affiliation":[{"name":"Centre d'imagerie M\u00e9dicale, 47, Boulevard du Pont Rouge, 15000 Aurillac, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Yves Carlier","sequence":"additional","affiliation":[{"name":"Department of Radiology, H\u00f4pital Raymond Poincar\u00e9, Assistance Publique-H\u00f4pitaux de Paris, Universit\u00e9 Paris Ile-de-France Ouest, 104 Boulevard Raymond Poincar\u00e9, 92380 Garches, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliette","family":"Thariat","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Antoine Lacassagne Cancer Research Institute, 33, Avenue Valombrose, 06189 Nice Cedex 1, France."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,1,1]]},"reference":[{"key":"bibr1-11-280","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.172.2.2748818"},{"key":"bibr2-11-280","doi-asserted-by":"publisher","DOI":"10.1177\/000348949910800109"},{"key":"bibr3-11-280","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.72B6.2246284"},{"key":"bibr4-11-280","first-page":"491","volume":"25","author":"Littrell L.A.","year":"2004","journal-title":"Am J Neuroradiol."},{"key":"bibr5-11-280","first-page":"1249","volume":"4","author":"Lo W.W.","year":"1983","journal-title":"Am J Neuroradiol."},{"key":"bibr6-11-280","first-page":"1231","volume":"19","author":"Martin M.L.","year":"1998","journal-title":"Am J 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