{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:19:38Z","timestamp":1777522778851,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the subtle clinical features, genetic considerations, and management of progressive postnatal pansynostosis, a rare form of multisutural craniosynostosis that insidiously occurs after birth and causes inconspicuous cranial changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design, Participants, Setting<\/jats:title>\n                    <jats:p>The study is a retrospective chart review of all patients diagnosed with progressive postnatal pansynostosis at a major craniofacial center between 2000 and 2009. Patients with kleebattsch\u00e4del were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nineteen patients fit our inclusion criteria. Fifteen patients had a syndromic diagnosis: Crouzon syndrome (n = 8), Saethre-Chotzen syndrome (n = 5), and Pfeiffer syndrome (n = 2). With the exception of one patient with moderate turricephaly, all patients had a relatively normal head shape with cranial indices ranging from 0.72 to 0.93 (mean, 0.81). Patients were diagnosed at an average of 32.4 months; craniosynostosis was suspected based on declining percentile head circumference (n = 14), detection of an apical prominence (n = 12), papilledema (n = 7), and worsening exorbitism (n = 3). Nearly all patients had evidence of increased intracranial pressure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Progressive postnatal pansynostosis is insidious; diagnosis is typically delayed because the clinical signs are subtle and appear gradually. All infants or children with known or suspected craniosynostotic disorder and a normal head shape should be carefully monitored; computed tomography is indicated if there is any decrease in percentile head circumference or symptoms of intracranial pressure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1597\/14-092","type":"journal-article","created":{"date-parts":[[2014,10,28]],"date-time":"2014-10-28T16:27:17Z","timestamp":1414513637000},"page":"751-757","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Progressive Postnatal Pansynostosis"],"prefix":"10.1177","volume":"52","author":[{"given":"Gary F.","family":"Rogers","sequence":"first","affiliation":[{"name":"George Washington School of Medicine, Children's National Medical Center, Washington, DC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arin K.","family":"Greene","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, Massachusetts."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark R.","family":"Proctor","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Department of Neurosurgery, Boston Children's Hospital, Boston, Massachusetts."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John B.","family":"Mulliken","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Cleft and Craniofacial Program, Boston Children's Hospital, Boston, Massachusetts."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan M.","family":"Goobie","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Department of Anesthesia, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joan M.","family":"Stoler","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Division of Genetics, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,1,3]]},"reference":[{"key":"bibr1-14-092","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1997.86.2.0177"},{"key":"bibr2-14-092","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1993_030_0401_ioofc_2.3.co_2"},{"key":"bibr3-14-092","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000111593.96440.30"},{"key":"bibr4-14-092","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-007-0469-4"},{"key":"bibr5-14-092","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)70401-5"},{"key":"bibr6-14-092","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181d62b48"},{"key":"bibr7-14-092","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1995.83.4.0733"},{"key":"bibr8-14-092","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31817f45f0"},{"key":"bibr9-14-092","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-200403000-00013"},{"key":"bibr10-14-092","doi-asserted-by":"publisher","DOI":"10.1159\/000090463"},{"key":"bibr11-14-092","doi-asserted-by":"publisher","DOI":"10.1007\/BF00300715"},{"key":"bibr12-14-092","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199003000-00011"},{"key":"bibr13-14-092","doi-asserted-by":"publisher","DOI":"10.1016\/S0929-693X(97)83408-2"},{"key":"bibr14-14-092","first-page":"1011","volume":"110","author":"Rogers 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