{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T02:59:32Z","timestamp":1793415572945,"version":"4.5.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Parry-Romberg syndrome (PRS) is a rare craniofacial disease that causes progressive hemifacial atrophy of the soft tissue before spontaneously entering remission. Autologous fat grafting may provide a less invasive alternative, producing aesthetically pleasing results while avoiding the need for traditional microsurgical free flap coverage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic review of the literature was conducted. Inclusion and exclusion criteria were applied. The case report highlights the technique using two-dimensional and three-dimensional photography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Our review yielded 31 articles in addition to our case describing 147 cases of lipofilling to correct PRS soft-tissue defects. Patients underwent an average of 2.2 procedures, receiving on average 95 mL of grafted fat. Disease severity was classified into mild (41%), moderate (42%), and severe (17%) in the identified patients. Increasing disease severity correlated with an increasing number of procedures and fat-grafting volumes to achieve adequate aesthetic outcomes (mean, 1.5 and 38 mL; 2.3 and 81 mL; 3.7 and 129 mL, respectively). Reported benefits over flap-based reconstructions included reductions in cost (40%), operative time (50%), donor-site morbidity (52%), and rate of complications (33%). Aesthetic benefits cited included improved skin quality (65%), more natural contours (1%), and more natural facial expressions (10%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Fat grafting for correction of PRS-associated soft-tissue defects is receiving heightened acceptance for its ability to restore natural facial contours. While additional fat-grafting procedures may be required with increased disease severity, autologous fat grafting may be a beneficial option as a sole modality to correct PRS-associated soft-tissue atrophy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1597\/14-232","type":"journal-article","created":{"date-parts":[[2015,8,21]],"date-time":"2015-08-21T10:40:01Z","timestamp":1440153601000},"page":"339-350","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":37,"title":["Evaluating Autologous Lipofilling for Parry-Romberg Syndrome\u2013Associated Defects: A Systematic Literature Review and Case Report"],"prefix":"10.1177","volume":"53","author":[{"given":"Katherine A.","family":"Rodby","sequence":"first","affiliation":[{"name":"University of Illinois at Chicago, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne E.","family":"Kaptein","sequence":"additional","affiliation":[{"name":"University of Illinois at Chicago, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Roring","sequence":"additional","affiliation":[{"name":"University of Illinois at Chicago, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan J.","family":"Jacobs","sequence":"additional","affiliation":[{"name":"University of Illinois at Chicago, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicky","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Rush University Medical Center, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina P.","family":"Quinn","sequence":"additional","affiliation":[{"name":"University of Illinois at Chicago, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anuja K.","family":"Antony","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Rush University Medical Center, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,5,1]]},"reference":[{"key":"bibr1-14-232","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962011000700022"},{"key":"bibr2-14-232","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2006.32230.x"},{"key":"bibr3-14-232","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2009.09.017"},{"key":"bibr4-14-232","doi-asserted-by":"publisher","DOI":"10.5999\/aps.2012.39.6.659"},{"key":"bibr5-14-232","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-008-9223-x"},{"key":"bibr6-14-232","first-page":"1465","volume":"39","author":"Chang Q.","year":"2013","journal-title":"Dermatol 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