{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T06:01:35Z","timestamp":1780466495170,"version":"3.54.1"},"reference-count":41,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this study was to radiographically investigate the prevalence of dental anomalies outside the cleft area in a group of Brazilian patients with nonsyndromic cleft lip and\/or palate (NSCL\/P).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design, Participants, and Setting<\/jats:title>\n                    <jats:p>A retrospective analysis of 207 panoramic radiographs of patients with NSCL\/P aged 12 to 45 years without history of tooth extraction and orthodontic treatment was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Dental anomalies were found in 75.4% of the patients, and tooth agenesis (29.2%) and supernumerary tooth (2.6%) were the most common anomalies. The risk of agenesis was higher among the individuals with cleft palate (CP) compared with individuals with cleft lip (CL) and cleft lip and palate (CLP) (agenesis: CP versus CL: odds ratio 6.27, 95% confidence interval 2.21-17.8, P = .0003; CP versus CLP: odds ratio 2.94; 95% confidence interval 1.27-6.81, P = .01). The frequency of dental agenesis was higher in patients with unilateral complete CLP (agenesis: P &lt; .0001), incomplete bilateral CLP (agenesis: P = .0013), complete CP (agenesis: P &lt; .0001), and incomplete CP (agenesis: P &lt; .0001). The frequency of supernumerary teeth was higher in patients with bilateral complete CLP ( P &lt; .0001). The frequency of dental agenesis ( P &lt; .0001) and ectopic tooth ( P = .009) was higher than the frequency estimated for general population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The prevalence of dental anomalies in patients with NSCL\/P was higher than that reported in overall population. This study found preferential associations between dental anomalies and specific extensions of NSCL\/P, suggesting that dental agenesis and ectopic tooth may be part of oral cleft subphenotypes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1597\/14-303","type":"journal-article","created":{"date-parts":[[2015,11,17]],"date-time":"2015-11-17T17:19:50Z","timestamp":1447780790000},"page":"714-719","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Dental Anomalies in a Brazilian Cleft Population"],"prefix":"10.1177","volume":"53","author":[{"given":"Jamile","family":"S\u00e1","sequence":"first","affiliation":[{"name":"Department of Basic Science, Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorena C.","family":"Mariano","sequence":"additional","affiliation":[{"name":"Department of Basic Science, Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daiane","family":"Cangu\u00e7u","sequence":"additional","affiliation":[{"name":"Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thaynara S.L.","family":"Coutinho","sequence":"additional","affiliation":[{"name":"School of Dentistry, Jos\u00e9 do Ros\u00e1rio Vellano University, Alfenas, Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuichi","family":"Hoshi","sequence":"additional","affiliation":[{"name":"Department of Basic Science, Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alena Peixoto","family":"Medrado","sequence":"additional","affiliation":[{"name":"Department of Basic Science, Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herc\u00edlio","family":"Martelli-Junior","sequence":"additional","affiliation":[{"name":"Stomatology Clinic, Dental School, State University of Montes Claros, Montes Claros, Minas Gerais, Brazil"},{"name":"School of Dentistry, Jos\u00e9 do Ros\u00e1rio Vellano University, Alfenas, Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo D.","family":"Coletta","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis, School of Dentistry, State University of Campinas, Piracicaba, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia R.A.","family":"Reis","sequence":"additional","affiliation":[{"name":"Department of Basic Science, Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,11,1]]},"reference":[{"key":"bibr1-14-303","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjp156"},{"key":"bibr2-14-303","doi-asserted-by":"publisher","DOI":"10.1597\/08-275.1"},{"key":"bibr3-14-303","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1002\/bdra.20659","volume":"88","author":"Blanton S.H.","year":"2010","journal-title":"Birth Defects Res A Clin Mol 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