{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T06:47:02Z","timestamp":1784530022693,"version":"3.55.0"},"reference-count":54,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the temporal pattern of otitis media with effusion (OME) resolution for a cohort of nonsyndromic cleft palate children enrolled before palatoplasty and followed through 5 years of age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>This is a prospective, longitudinal study of the time course for OME resolution in infants and children with palatal clefts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Cleft Palate Craniofacial Center of a tertiary care pediatric hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>This study included 52 children with cleft palate (29 boys, 45 white, Veau 1 through 4) who had a Furlow-type palatoplasty between 10 and 24 months of age performed by one of six surgeons.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Standard cleft palate management was supplemented with study visits to the research clinic pre- and postpalatoplasty and then yearly to 6 years of age for assessments of middle ear status by interval history, otoscopy, and tympanometry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measure<\/jats:title>\n                    <jats:p>The main outcome measure was age at otitis media resolution defined as the age in years at the first in a sequence of \u201cdisease-free\u201d diagnoses not interrupted or followed by any other diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The cumulative percent OME resolution for ears\/children at ages &lt;1, 1, 2, 3, 4, 5 years was 4.1\/4.4, 14.3\/10.9, 31.6\/21.7, 45.9\/37.0, 56.1\/50.0, and 70.4\/60.9%. OME resolution followed a simple linear time curve with slopes of 13.5% (confidence interval [CI] = 12.2% to 14.8%, r\n                      <jats:sup>2<\/jats:sup>\n                      = .99) and 11.9% (CI = 10.1% to 13.6%, r\n                      <jats:sup>2<\/jats:sup>\n                      = .99) resolutions per year for ears and children, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There is a natural, age-related pattern of resolution for persistent OME that affects most infants and young children with cleft palate that is not affected by palatoplasty.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1597\/15-130","type":"journal-article","created":{"date-parts":[[2016,8,17]],"date-time":"2016-08-17T18:18:41Z","timestamp":1471457921000},"page":"607-613","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Resolution of Otitis Media with Effusion in Children with Cleft Palate Followed through Five Years of Age"],"prefix":"10.1177","volume":"53","author":[{"given":"Cuneyt M.","family":"Alper","sequence":"first","affiliation":[{"name":"Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, and Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph E.","family":"Losee","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center and the University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James T.","family":"Seroky","sequence":"additional","affiliation":[{"name":"University of Pittsburgh, Pittsburgh, Pennsylvania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen M.","family":"Mandel","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beverly C.","family":"Richert","sequence":"additional","affiliation":[{"name":"University of Pittsburgh, Pittsburgh, Pennsylvania, and Certified Registered Nurse Practitioner, Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J.","family":"Doyle","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,9,1]]},"reference":[{"key":"bibr1-15-130","doi-asserted-by":"publisher","DOI":"10.1597\/10-009"},{"key":"bibr2-15-130","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1976.00780130059005"},{"key":"bibr3-15-130","volume-title":"Eustachian Tube Structure, Function, Role in Otitis Media.","author":"Bluestone C.D.","year":"2005"},{"key":"bibr4-15-130","volume-title":"Otitis Media in Infants and Children.","author":"Bluestone C.D.","year":"2007","edition":"5"},{"key":"bibr5-15-130","first-page":"543","volume":"39","author":"Butow K.W.","year":"1984","journal-title":"J Dent Assoc S 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