{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:18:56Z","timestamp":1777522736690,"version":"3.51.4"},"reference-count":49,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine whether the clinical presentation or severity of sleep disordered breathing differs between children with or without a history of cleft lip and\/or palate (CL\/P) presenting for sleep assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective chart review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tertiary care pediatric hospital cleft clinic, sleep clinic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients<\/jats:title>\n                    <jats:p>Children &gt; 6 months of age presenting to the cleft clinic with sleep concerns and children without CL\/P presenting to the sleep clinic in the same 2-year period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcomes Measures<\/jats:title>\n                    <jats:p>Clinical symptoms and overnight polysomnography (PSG) results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 168 children (55 from cleft clinic, 113 from sleep clinic) were identified. Age at clinical review (6.6 \u00b1 4.1 years versus 6.8 \u00b1 4.0 years, P = ns), sex distribution (64.6% versus 58.4%, P = ns), and the presence of syndromes or significant medical conditions (12% versus 16%, P = ns) were similar between groups. Snoring was the reason for referral in 59% of children with CL\/P and 69% of non-CL\/P children ( P = ns). The only presenting feature that differentiated between the groups was a lower incidence of tonsillar enlargement in children with CL\/P (33% versus 79%, chi-square 30.4, P &lt; 0.001). Sleep study results showed similar apnea-hypopnea indices (6.2 \u00b1 6.9 versus 7.9 \u00b1 7.1 events\/hr, P = ns) with more central apnea in children with CL\/P (1.5 \u00b1 1.5 versus 1.0 \u00b1 1.0 events\/hr, P = 0.017).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Snoring and obstructive sleep apnea are common in CL\/P with less tonsillar enlargement than non-CL\/P children. Children with CL\/P have similar OSA severity compared to non-cleft children but more central apnea which may indicate differences in the control of breathing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1597\/15-309","type":"journal-article","created":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T17:22:02Z","timestamp":1466616122000},"page":"523-529","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of Clinical Symptoms and Severity of Sleep Disordered Breathing in Children with and without Cleft Lip and\/or Palate"],"prefix":"10.1177","volume":"54","author":[{"given":"Joanna E","family":"Maclean","sequence":"first","affiliation":[{"name":"Division of Respiratory Medicine, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada. David Fitzsimons is Speech Pathologist, Discipline of Paediatrics & Child Health, Physiology University of Sydney, Sydney, NSW, Australia, and Speech Pathologist, Cleft Palate Clinic, The Children's Hospital at Westmead, Westmead, NSW, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Fitzsimons","sequence":"additional","affiliation":[{"name":"Professor, Discipline of Paediatrics & Child Health, University of Sydney, Sydney, NSW, Australia, and Pediatric Respiratory Physician, Department of Respiratory Medicine, The Children's Hospital at Westmead, Westmead, NSW, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominic","family":"Fitzgerald","sequence":"additional","affiliation":[{"name":"Discipline of Paediatrics & Child Health, and Department of Physiology University of Sydney, and Pediatric Respiratory Physician, The Children's Hospital at Westmead, Westmead, NSW, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Waters","sequence":"additional","affiliation":[{"name":"Discipline of Paediatrics & Child Health, and Department of Physiology University of Sydney, and Pediatric Respiratory Physician, The Children's Hospital at Westmead, Westmead, NSW, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,9,1]]},"reference":[{"key":"bibr1-15-309","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1997_034_0256_rsosaf_2.3.co_2"},{"key":"bibr2-15-309","doi-asserted-by":"publisher","DOI":"10.1136\/adc.68.3.360"},{"key":"bibr3-15-309","author":"American Cleft Palate-Craniofacial Association","year":"2009","journal-title":"Chapel Hill, NC: American Cleft Palate-Craniofacial Association"},{"key":"bibr4-15-309","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.099762"},{"key":"bibr5-15-309","unstructured":"Australasian Sleep Association, ASTA\/ASA addendum to AASM Guidelines for recording and scoring paediatric sleep, April 2011. 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