{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T21:15:56Z","timestamp":1794431756628,"version":"4.9.1"},"reference-count":29,"publisher":"Begell House","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Long Term Eff Med Implants"],"published-print":{"date-parts":[[2025]]},"abstract":"<p>&lt;b&gt;Background:&lt;\/b&gt; Peri-implant disease pathogenesis results in production of pro-inflammatory mediators. These mediators alter the redox balance leading to decrease in antioxidants. The aim of the study was to compare the levels of interleukin-6 (IL-6) and superoxide dismutase (SOD) in peri-implant health and diseases.\n\n&lt;b&gt;Materials and methods:&lt;\/b&gt; The present observational study was carried out from March 2023 to September 2023 in the Department of Implantology, Saveetha Dental College and Hospitals, Chennai, India. A total of 60 patients with peri-implant health (&lt;i&gt;n&lt;\/i&gt; &amp;#61; 20), peri-implant mucositis (&lt;i&gt;n&lt;\/i&gt; &amp;#61; 20) and peri-implantitis (&lt;i&gt;n&lt;\/i&gt; &amp;#61; 20) were enrolled. Unstimulated salivary samples were collected and subjected to ELISA for IL-6 and SOD analysis. IL-6 and SOD levels were then compared between the groups using ANOVA.\n\n&lt;b&gt;Results:&lt;\/b&gt; There was a statistically significant difference in IL-6 and SOD levels between the three groups with p value of 0.003 and 0.000 respectively.\n\n&lt;b&gt;Conclusion:&lt;\/b&gt; The present study suggests that IL-6 level increases and SOD level decreases with severity of peri-implant diseases.\n<\/p>","DOI":"10.1615\/jlongtermeffmedimplants.2025052691","type":"journal-article","created":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T15:11:27Z","timestamp":1740669087000},"page":"77-81","source":"Crossref","is-referenced-by-count":5,"title":["Inflammatory and Antioxidant Status in Peri-Implant Health and Diseases: A Biochemical Analysis"],"prefix":"10.1615","volume":"35","author":[{"given":"Poulami","family":"Chakraborty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvina","family":"Rajasekar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"613","reference":[{"key":"2","doi-asserted-by":"crossref","unstructured":"Heitz\u00e2\u0080\u0090Mayfield LJ, Salvi GE. 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