{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T04:05:33Z","timestamp":1779509133123,"version":"3.53.1"},"reference-count":37,"publisher":"Tohoku University Medical Press","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tohoku J. Exp. Med."],"published-print":{"date-parts":[[2026]]},"DOI":"10.1620\/tjem.2025.j112","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T22:06:52Z","timestamp":1758751612000},"page":"505-512","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of Information-Motivation-Behavioral Skills Model of Hypothyroidism Self-Management Integrated into Prenatal Care in Pregnant Women with Newly Diagnosed Hypothyroidism"],"prefix":"10.1620","volume":"268","author":[{"given":"He","family":"Li","sequence":"first","affiliation":[{"name":"Obstetrical Department, the First Affiliated Hospital of Bengbu Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Fang","family":"Shao","sequence":"additional","affiliation":[{"name":"Obstetrical Department, the First Affiliated Hospital of Bengbu Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zheng","sequence":"additional","affiliation":[{"name":"Obstetrical Department, the First Affiliated Hospital of Bengbu Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Qian","family":"Chen","sequence":"additional","affiliation":[{"name":"Obstetrical Department, the First Affiliated Hospital of Bengbu Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, the First Affiliated Hospital of Bengbu Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"622","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"Abadi, K.K., Jama, A.H., Legesse, A.Y.&amp;Gebremichael, A.K. (2023)  Prevalence of Hypothyroidism in Pregnancy and Its Associations with Adverse Pregnancy Outcomes Among Pregnant Women in A General Hospital: A Cross-Sectional Study. <i>Int. J. Womens Health<\/i>, 15, 1481-1490. https:\/\/doi.org\/10.2147\/IJWH.S429611","DOI":"10.2147\/IJWH.S429611"},{"key":"2","doi-asserted-by":"publisher","unstructured":"Abalovich, M., Vazquez, A., Alcaraz, G., Kitaigrodsky, A., Szuman, G., Calabrese, C., Astarita, G., Frydman, M.&amp;Gutierrez, S. (2013)  Adequate levothyroxine doses for the treatment of hypothyroidism newly discovered during pregnancy. <i>Thyroid<\/i>, 23, 1479-1483. https:\/\/doi.org\/10.1089\/thy.2013.0024","DOI":"10.1089\/thy.2013.0024"},{"key":"3","doi-asserted-by":"publisher","unstructured":"Baishya, A.&amp;Metri, K. (2024)  Effects of yoga on hypothyroidism: A systematic review. <i>J. Ayurveda Integr. Med.<\/i>, 15, 100891. https:\/\/doi.org\/10.1016\/j.jaim.2024.100891","DOI":"10.1016\/j.jaim.2024.100891"},{"key":"4","doi-asserted-by":"publisher","unstructured":"Cheung, S.K.&amp;Sun, S.Y. (1999)  Assessment of optimistic self-beliefs: further validation of the Chinese version of the General Self-Efficacy Scale. <i>Psychol. Rep.<\/i>, 85, 1221-1224. https:\/\/doi.org\/10.2466\/pr0.1999.85.3f.1221","DOI":"10.2466\/pr0.1999.85.3f.1221"},{"key":"5","doi-asserted-by":"publisher","unstructured":"Chin, W.Y., Choi, E.P., Chan, K.T.&amp;Wong, C.K. (2015)  The Psychometric Properties of the Center for Epidemiologic Studies Depression Scale in Chinese Primary Care Patients: Factor Structure, Construct Validity, Reliability, Sensitivity and Responsiveness. <i>PLoS One<\/i>, 10, e0135131. https:\/\/doi.org\/10.1371\/journal.pone.0135131","DOI":"10.1371\/journal.pone.0135131"},{"key":"6","doi-asserted-by":"publisher","unstructured":"Fisher, J.D., Fisher, W.A., Misovich, S.J., Kimble, D.L.&amp;Malloy, T.E. (1996)  Changing AIDS risk behavior: effects of an intervention emphasizing AIDS risk reduction information, motivation, and behavioral skills in a college student population. <i>Health Psychol.<\/i>, 15, 114-123. https:\/\/doi.org\/10.1037\/\/0278-6133.15.2.114","DOI":"10.1037\/\/0278-6133.15.2.114"},{"key":"7","doi-asserted-by":"publisher","unstructured":"Frank, A.S., Lupattelli, A.&amp;Nordeng, H. (2018)  Risk factors for discontinuation of thyroid hormone replacement therapy in early pregnancy: a study from the Norwegian Mother and Child Cohort Study and the Medical Birth Registry of Norway. <i>Acta Obstet. Gynecol. Scand.<\/i>, 97, 852-860. https:\/\/doi.org\/10.1111\/aogs.13339","DOI":"10.1111\/aogs.13339"},{"key":"8","doi-asserted-by":"publisher","unstructured":"Kaplan, Z.B., Pearce, E.N., Lee, S.Y., Shin, H.M.&amp;Schmidt, R.J. (2024)  Maternal Thyroid Dysfunction During Pregnancy as an Etiologic Factor in Autism Spectrum Disorder: Challenges and Opportunities for Research. <i>Thyroid<\/i>, 34, 144-157. https:\/\/doi.org\/10.1089\/thy.2023.0391","DOI":"10.1089\/thy.2023.0391"},{"key":"9","doi-asserted-by":"publisher","unstructured":"Kini, V.&amp;Ho, P.M. (2018)  Interventions to Improve Medication Adherence: A Review. <i>JAMA<\/i>, 320, 2461-2473. https:\/\/doi.org\/10.1001\/jama.2018.19271","DOI":"10.1001\/jama.2018.19271"},{"key":"10","doi-asserted-by":"publisher","unstructured":"Knosgaard, L., Andersen, S., Hansen, A.B., Vestergaard, P.&amp;Andersen, S.L. (2023)  Maternal hypothyroidism and adverse outcomes of pregnancy.  <i>Clin. Endocrinol. <\/i>(<i>Oxf.<\/i>), 98, 719-729. https:\/\/doi.org\/10.1111\/cen.14853","DOI":"10.1111\/cen.14853"},{"key":"11","doi-asserted-by":"publisher","unstructured":"LaFranchi, S.H.(2021) Thyroid Function in Preterm\/Low Birth Weight Infants: Impact on Diagnosis and Management of Thyroid Dysfunction. <i>Front. Endocrinol.<\/i> (<i>Lausanne<\/i>), 12, 666207. https:\/\/doi.org\/10.3389\/fendo.2021.666207","DOI":"10.3389\/fendo.2021.666207"},{"key":"12","doi-asserted-by":"publisher","unstructured":"Luo, Z., Xue, L., Ma, L.&amp;Liu, Z. (2021)  Comorbid Anxiety and Depression and Related Factors Among Pregnant and Postpartum Chinese Women During the Coronavirus Disease 2019 Pandemic. <i>Front. Psychol.<\/i>, 12, 701629. https:\/\/doi.org\/10.3389\/fpsyg.2021.701629","DOI":"10.3389\/fpsyg.2021.701629"},{"key":"13","doi-asserted-by":"publisher","unstructured":"Matsui, D.(2012) Adherence with drug therapy in pregnancy. <i>Obstet. Gynecol. Int.<\/i>, 2012, 796590. https:\/\/doi.org\/10.1155\/2012\/796590","DOI":"10.1155\/2012\/796590"},{"key":"14","doi-asserted-by":"publisher","unstructured":"Mayhew, C.E., Simonson, K.R.&amp;Ellsworth Bowers, E.R. (2022)  Antepartum Care for Pregnant People with Overt Hypothyroidism, Subclinical Hypothyroidism, and Positive Thyroid Autoantibodies. <i>J. Midwifery Womens Health<\/i>, 67, 295-304. https:\/\/doi.org\/10.1111\/jmwh.13306","DOI":"10.1111\/jmwh.13306"},{"key":"15","doi-asserted-by":"publisher","unstructured":"Motahari-Tabari, N.S., Nasiri-Amiri, F., Faramarzi, M., Shirvani, M.A., Bakhtiari, A.&amp;Omidvar, S. (2023)  The Effectiveness of Information-Motivation-Behavioral Skills Model on Self-Care Practices in Early Pregnancy to Prevent Gestational Diabetes Mellitus in Iranian Overweight and Obese Women: A Randomized Controlled Trial. <i>Community Health Equity Res. Policy<\/i>, 43, 257-264. https:\/\/doi.org\/10.1177\/0272684X211020300","DOI":"10.1177\/0272684X211020300"},{"key":"16","doi-asserted-by":"publisher","unstructured":"Nafradi, L., Nakamoto, K.&amp;Schulz, P.J. (2017)  Is patient empowerment the key to promote adherence? A systematic review of the relationship between self-efficacy, health locus of control and medication adherence. <i>PLoS One<\/i>, 12, e0186458. https:\/\/doi.org\/10.1371\/journal.pone.0186458","DOI":"10.1371\/journal.pone.0186458"},{"key":"17","doi-asserted-by":"publisher","unstructured":"Nelson, L.A., Wallston, K.A., Kripalani, S., LeStourgeon, L.M., Williamson, S.E.&amp;Mayberry, L.S. (2018)  Assessing barriers to diabetes medication adherence using the Information-Motivation-Behavioral skills model. <i>Diabetes Res. Clin. Pract.<\/i>, 142, 374-384. https:\/\/doi.org\/10.1016\/j.diabres.2018.05.046","DOI":"10.1016\/j.diabres.2018.05.046"},{"key":"18","doi-asserted-by":"publisher","unstructured":"Pearce, E.N.(2022) Management of Hypothyroidism and Hypothyroxinemia During Pregnancy. <i>Endocr. Pract.<\/i>, 28, 711-718. https:\/\/doi.org\/10.1016\/j.eprac.2022.05.004","DOI":"10.1016\/j.eprac.2022.05.004"},{"key":"19","doi-asserted-by":"publisher","unstructured":"Peng, C.C., Maraka, S.&amp;Pearce, E.N. (2022)  Under and overtreatment with thyroid hormone replacement during pregnancy. <i>Curr. Opin. Endocrinol. Diabetes Obes.<\/i>, 29, 474-482. https:\/\/doi.org\/10.1097\/MED.0000000000000755","DOI":"10.1097\/MED.0000000000000755"},{"key":"20","doi-asserted-by":"publisher","unstructured":"Salas-Lucia, F.(2024) Mapping Thyroid Hormone Action in the Human Brain. <i>Thyroid<\/i>, 34, 815-826. https:\/\/doi.org\/10.1089\/thy.2024.0120","DOI":"10.1089\/thy.2024.0120"},{"key":"21","doi-asserted-by":"publisher","unstructured":"Schoenthaler, A., Leon, M., Butler, M., Steinhaeuser, K.&amp;Wardzinski, W. (2020)  Development and Evaluation of a Tailored Mobile Health Intervention to Improve Medication Adherence in Black Patients With Uncontrolled Hypertension and Type 2 Diabetes: Pilot Randomized Feasibility Trial. <i>JMIR Mhealth Uhealth<\/i>, 8, e17135. https:\/\/doi.org\/10.2196\/17135","DOI":"10.2196\/17135"},{"key":"22","doi-asserted-by":"publisher","unstructured":"Siscart, J., Oros, M., Serna, M.C., Perejon, D., Galvan, L.&amp;Ortega, M. (2022)  Adherence to treatment for hypothyroidism in pregnancy and relationship with thyrotropin control: a retrospective observational cohort study. <i>BMC Pregnancy Childbirth<\/i>, 22, 168. https:\/\/doi.org\/10.1186\/s12884-022-04483-8","DOI":"10.1186\/s12884-022-04483-8"},{"key":"23","doi-asserted-by":"publisher","unstructured":"Sisk, B.A., Mack, J.W.&amp;DuBois, J. (2019)  Knowing versus doing: The value of behavioral change models for emotional communication in oncology. <i>Patient Educ. Couns.<\/i>, 102, 2344-2348. https:\/\/doi.org\/10.1016\/j.pec.2019.07.023","DOI":"10.1016\/j.pec.2019.07.023"},{"key":"24","doi-asserted-by":"publisher","unstructured":"Staneva, A., Bogossian, F., Pritchard, M.&amp;Wittkowski, A. (2015)  The effects of maternal depression, anxiety, and perceived stress during pregnancy on preterm birth: A systematic review. <i>Women Birth<\/i>, 28, 179-193. https:\/\/doi.org\/10.1016\/j.wombi.2015.02.003","DOI":"10.1016\/j.wombi.2015.02.003"},{"key":"25","doi-asserted-by":"publisher","unstructured":"Su, Q., Zhang, H., Zhang, Y., Zhang, H., Ding, D., Zeng, J., Zhu, Z.&amp;Li, H. (2015)  Maternal Stress in Gestation: Birth Outcomes and Stress-Related Hormone Response of the Neonates. <i>Pediatr. Neonatol.<\/i>, 56, 376-381. https:\/\/doi.org\/10.1016\/j.pedneo.2015.02.002","DOI":"10.1016\/j.pedneo.2015.02.002"},{"key":"26","doi-asserted-by":"publisher","unstructured":"Tang, X., Lu, Z., Hu, D.&amp;Zhong, X. (2019)  Influencing factors for prenatal Stress, anxiety and depression in early pregnancy among women in Chongqing, China. <i>J. Affect. Disord.<\/i>, 253, 292-302. https:\/\/doi.org\/10.1016\/j.jad.2019.05.003","DOI":"10.1016\/j.jad.2019.05.003"},{"key":"27","doi-asserted-by":"crossref","unstructured":"Tanriverdi, A., Ozcan Kahraman, B., Ozsoy, I., Bayraktar, F., Ozgen Saydam, B., Acar, S., Ozpelit, E., Akdeniz, B.&amp;Savci, S. (2019)  Physical activity in women with subclinical hypothyroidism. <i>J. Endocrinol. Invest.<\/i>, 42, 779-785. https:\/\/doi.org\/10.1007\/s40618-018-0981-2","DOI":"10.1007\/s40618-018-0981-2"},{"key":"28","doi-asserted-by":"publisher","unstructured":"Tastekin Ouyaba, A.&amp;Cicekoglu Ozturk, P. (2022)  The effect of the information-motivation-behavioral skills (IMB) model variables on orthorexia nervosa behaviors of pregnant women. <i>Eat. Weight Disord.<\/i>, 27, 361-372. https:\/\/doi.org\/10.1007\/s40519-021-01237-x","DOI":"10.1007\/s40519-021-01237-x"},{"key":"29","doi-asserted-by":"publisher","unstructured":"Taylor, P.N., Medici, M.M., Hubalewska-Dydejczyk, A.&amp;Boelaert, K. (2024)  Hypothyroidism. <i>Lancet<\/i>, 404, 1347-1364. https:\/\/doi.org\/10.1016\/S0140-6736(24)01614-3","DOI":"10.1016\/S0140-6736(24)01614-3"},{"key":"30","doi-asserted-by":"publisher","unstructured":"Topaloglu, O., Yavuz, A.&amp;Tiryaki Aylikci, A.B. (2021)  Evaluation of adherence to levothyroxine and out-of-range thyroid-stimulating hormone levels in pregnant women with primary hypothyroidism. <i>Int. J. Clin. Pract.<\/i>, 75, e14312. https:\/\/doi.org\/10.1111\/ijcp.14312","DOI":"10.1111\/ijcp.14312"},{"key":"31","doi-asserted-by":"publisher","unstructured":"Urgatz, B.&amp;Poppe, K.G. (2024)  Update on therapeutic use of levothyroxine for the management of hypothyroidism during pregnancy. <i>Endocr. Connect.<\/i>, 13, e230420. https:\/\/doi.org\/10.1530\/EC-23-0420","DOI":"10.1530\/EC-23-0420"},{"key":"32","doi-asserted-by":"publisher","unstructured":"Wozniak, D., Drzymala, S., Przyslawski, J.&amp;Drzymala-Czyz, S. (2021)  Dietary supplements in hypothyroidism. <i>Acta Sci. Pol.Technol. Aliment.<\/i>, 20, 375-381. https:\/\/doi.org\/10.17306\/J.AFS.0985","DOI":"10.17306\/J.AFS.0985"},{"key":"33","doi-asserted-by":"publisher","unstructured":"Wu, K., Zhou, Y., Ke, S., Huang, J., Gao, X., Li, B., Lin, X., Liu, X., Liu, X., Ma, L., Wang, L., Wu, L., Wu, L., Xie, C., Xu, J., et al.(2021)  Lifestyle is associated with thyroid function in subclinical hypothyroidism: a cross-sectional study. <i>BMC Endocr. Disord.<\/i>, 21, 112. https:\/\/doi.org\/10.1186\/s12902-021-00772-z","DOI":"10.1186\/s12902-021-00772-z"},{"key":"34","doi-asserted-by":"publisher","unstructured":"Xu, H.&amp;Wang, J. (2023)  An information-motivation-behavioral skills model-based intervention for patients with epilepsy. <i>Epilepsy Behav.<\/i>, 147, 109408. https:\/\/doi.org\/10.1016\/j.yebeh.2023.109408","DOI":"10.1016\/j.yebeh.2023.109408"},{"key":"35","doi-asserted-by":"publisher","unstructured":"Xu, L., Fang, L., Xu, Q.&amp;Shen, D. (2023)  Study on the effect of intervention on postpartum psychological improvement and body recovery of caesarean section women based on information-motivation-behavioural skills model. <i>Nurs. Open<\/i>, 10, 4705-4712. https:\/\/doi.org\/10.1002\/nop2.1720","DOI":"10.1002\/nop2.1720"},{"key":"36","doi-asserted-by":"publisher","unstructured":"Yan, J., You, L.M., Yang, Q., Liu, B., Jin, S., Zhou, J., Lin, C.&amp;Morisky, D.E. (2014)  Translation and validation of a Chinese version of the 8-item Morisky medication adherence scale in myocardial infarction patients. <i>J. Eval. Clin. Pract.<\/i>, 20, 311-317. https:\/\/doi.org\/10.1111\/jep.12125","DOI":"10.1111\/jep.12125"},{"key":"37","doi-asserted-by":"publisher","unstructured":"You, H., Wang, Y.Y., Zhang, C., Walker, A.N., Ge, J.J., Zhao, S.Q.&amp;Peng, X.Q. (2023)  Empirical validation of the information-motivation-behavioral skills model of gestational weight management behavior: a framework for intervention. <i>BMC Public Health<\/i>, 23, 130. https:\/\/doi.org\/10.1186\/s12889-023-15067-2","DOI":"10.1186\/s12889-023-15067-2"}],"container-title":["The Tohoku Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/tjem\/268\/4\/268_2025.J112\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T03:27:25Z","timestamp":1779506845000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/tjem\/268\/4\/268_2025.J112\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":37,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.1620\/tjem.2025.j112","relation":{},"ISSN":["0040-8727","1349-3329"],"issn-type":[{"value":"0040-8727","type":"print"},{"value":"1349-3329","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"2025.J112"}}