{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T01:13:17Z","timestamp":1773277997585,"version":"3.50.1"},"reference-count":19,"publisher":"Tohoku University Medical Press","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tohoku J. Exp. Med."],"published-print":{"date-parts":[[2010]]},"DOI":"10.1620\/tjem.222.39","type":"journal-article","created":{"date-parts":[[2010,8,30]],"date-time":"2010-08-30T06:09:20Z","timestamp":1283148560000},"page":"39-44","source":"Crossref","is-referenced-by-count":19,"title":["Sunitinib-Induced Thyrotoxicosis Followed by Persistent Hypothyroidism with Shrinkage of Thyroid Volume"],"prefix":"10.1620","volume":"222","author":[{"given":"Kanako","family":"Sakurai","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Metabolism, KKR Suifu Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Fukazawa","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, KKR Suifu Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zenei","family":"Arihara","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, KKR Suifu Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsumi","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Clinical Science, Tohoku University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"622","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"Alexandrescu, D.T., Popoveniuc, G., Farzanmehr, H., Dasanu, C.A., Dawson, N. &amp; Wartofsky, L. (2008) Sunitinib-associated lymphocytic thyroiditis without circulating antithyroid antibodies. <i>Thyroid<\/i>, <b>18<\/b>, 809-812.","DOI":"10.1089\/thy.2007.0349"},{"key":"2","doi-asserted-by":"crossref","unstructured":"Atkins, M.B., Mier, J.W., Parkinson, D.R., Gould, J.A., Berkman, E.M. &amp; Kaplan, M.M. (1988) Hypothyroidism after treatment with interleukin-2 and lymphokine-activated killer cells. <i>N. Engl. J. Med<\/i>., <b>318<\/b>, 1557-1563.","DOI":"10.1056\/NEJM198806163182401"},{"key":"3","doi-asserted-by":"crossref","unstructured":"Brunn, J., Block, U., Ruf, G., Bos, I., Kunze, W.P. &amp; Scriba, P.C. (1981) Volumetric analysis of thyroid lobes by real-time ultrasound. <i>Dtsch. Med. Wochenschr<\/i>., <b>106<\/b>, 1338-1340.","DOI":"10.1055\/s-2008-1070506"},{"key":"4","doi-asserted-by":"crossref","unstructured":"Desai, J., Yassa, L., Marqusee, E., George, S., Frates, M.C., Chen, M.H., Morgan, J.A., Dychter, S.S., Larsen, P.R., Demetri, G.D. &amp; Alexander, E.K. (2006) Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors. <i>Ann. Intern. Med<\/i>., <b>145<\/b>, 660-664.","DOI":"10.7326\/0003-4819-145-9-200611070-00008"},{"key":"5","doi-asserted-by":"crossref","unstructured":"Faris, J.E., Moore, A.F. &amp; Daniels, G.H. (2007) Sunitinib (sutent)-induced thyrotoxicosis due to destructive thyroiditis: a case report. <i>Thyroid<\/i>, <b>17<\/b>, 1147-1149.","DOI":"10.1089\/thy.2007.0104"},{"issue":"2","key":"6","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1200\/JCO.1999.17.2.529","volume":"17","author":"FRANZKE A","year":"1999","ISSN":"https:\/\/id.crossref.org\/issn\/0732-183X","issn-type":"print"},{"key":"7","doi-asserted-by":"crossref","unstructured":"Grossmann, M., Premaratne, E., Desai, J. &amp; Davis, I.D. (2008) Thyrotoxicosis during sunitinib treatment for renal cell carcinoma. <i>Clin. Endocrinol.(Oxf)<\/i>, <b>69<\/b>, 669-672.","DOI":"10.1111\/j.1365-2265.2008.03253.x"},{"key":"8","doi-asserted-by":"crossref","unstructured":"Mandac, J.C., Chaudhry, S., Sherman, K.E. &amp; Tomer, Y. (2006) The clinical and physiological spectrum of interferon-alpha induced thyroiditis: toward a new classification. <i>Hepatology<\/i>, <b>43<\/b>, 661-672.","DOI":"10.1002\/hep.21146"},{"key":"9","doi-asserted-by":"crossref","unstructured":"Mannavola, D., Coco, P., Vannucchi, G., Bertuelli, R., Carletto, M., Casali, P.G., Beck-Peccoz, P. &amp; Fugazzola, L. (2007) A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake. <i>J. Clin. Endocrinol. Metab<\/i>., <b>92<\/b>, 3531-3534.","DOI":"10.1210\/jc.2007-0586"},{"key":"10","unstructured":"Mendel, D.B., Laird, A.D., Xin, X., Louie, S.G., Christensen, J.G., Li, G., Schreck, R.E., Abrams, T.J., Ngai, T.J., Lee, L.B., Murray, L.J., Carver, J., Chan, E., Moss, K.G., Haznedar, J.O., Sukbuntherng, J., Blake, R.A., Sun, L., Tang, C., Miller, T., Shirazian, S., McMahon, G. &amp; Cherrington, J.M. (2003) In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic\/pharmacodynamic relationship. <i>Clin. Cancer Res<\/i>., <b>9<\/b>, 327-337."},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2001.01381.x"},{"key":"12","doi-asserted-by":"crossref","unstructured":"Nikolai, T.F., Brosseau, J., Kettrick, M.A., Roberts, R. &amp; Beltaos, E. (1980) Lymphocytic thyroiditis with spontaneously resolving hyperthyroidism (silent thyroiditis). <i>Arch. Intern. Med<\/i>., <b>140<\/b>, 478-482.","DOI":"10.1001\/archinte.1980.00330160038023"},{"key":"13","doi-asserted-by":"crossref","unstructured":"O'Farrell, A.M., Abrams, T.J., Yuen, H.A., Ngai, T.J., Louie, S.G., Yee, K.W., Wong, L.M., Hong, W., Lee, L.B., Town, A., Smolich, B.D., Manning, W.C., Murray, L.J., Heinrich, M.C. &amp; Cherrington, J.M. (2003) SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. <i>Blood<\/i>, <b>101<\/b>, 3597-3605.","DOI":"10.1182\/blood-2002-07-2307"},{"issue":"5","key":"14","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1530\/eje.0.1320587","volume":"132","year":"1995","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"key":"15","doi-asserted-by":"crossref","unstructured":"Rini, B.I., Tamaskar, I., Shaheen, P., Salas, R., Garcia, J., Wood, L., Reddy, S., Dreicer, R. &amp; Bukowski, R.M. (2007) Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib. <i>J. Natl. Cancer Inst<\/i>., <b>99<\/b>, 81-83.","DOI":"10.1093\/jnci\/djk008"},{"key":"16","doi-asserted-by":"crossref","unstructured":"Rogiers, A., Wolter, P., Op de Beeck, K., Thijs, M., Decallonne, B. &amp; Sch&ouml;ffski, P. (2010) Shrinkage of thyroid volume in sunitinib-treated patients with renal-cell carcinoma: a potential marker of irreversible thyroid dysfunction? <i>Thyroid<\/i>, <b>20<\/b>, 317-322.","DOI":"10.1089\/thy.2009.0125"},{"key":"17","doi-asserted-by":"crossref","unstructured":"Roti, E., Minelli, R., Gardini, E., Bianconi, L. &amp; Braverman, L.E. (1993) Thyrotoxicosis followed by hypothyroidism in patients treated with amiodarone. A possible consequence of a destructive process in the thyroid. <i>Arch. Intern. Med<\/i>., <b>153<\/b>, 886-892.","DOI":"10.1001\/archinte.1993.00410070068010"},{"key":"18","doi-asserted-by":"crossref","unstructured":"Wolter, P., Dumez, H. &amp; Schoffski, P. (2007) Sunitinib and hypothyroidism. <i>N. Engl. J. Med<\/i>., <b>356<\/b>, 1580; author reply 1580-1581.","DOI":"10.1056\/NEJMc070327"},{"key":"19","doi-asserted-by":"crossref","unstructured":"Wolter, P., Stefan, C., Decallonne, B., Dumez, H., Bex, M., Carmeliet, P. &amp; Sch&ouml;ffski, P. (2008) The clinical implications of sunitinib-induced hypothyroidism: a prospective evaluation. <i>Br. J. Cancer<\/i>, <b>99<\/b>, 448-454.","DOI":"10.1038\/sj.bjc.6604497"}],"container-title":["The Tohoku Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/tjem\/222\/1\/222_1_39\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,28]],"date-time":"2021-04-28T19:38:53Z","timestamp":1619638733000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/tjem\/222\/1\/222_1_39\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1620\/tjem.222.39","relation":{},"ISSN":["0040-8727","1349-3329"],"issn-type":[{"value":"0040-8727","type":"print"},{"value":"1349-3329","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}