{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T04:38:01Z","timestamp":1720327081532},"reference-count":18,"publisher":"Tohoku University Medical Press","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tohoku J. Exp. Med."],"published-print":{"date-parts":[[2018]]},"DOI":"10.1620\/tjem.246.167","type":"journal-article","created":{"date-parts":[[2018,11,16]],"date-time":"2018-11-16T22:34:46Z","timestamp":1542407686000},"page":"167-174","source":"Crossref","is-referenced-by-count":3,"title":["L-Type Amino Acid Transporter 1 Immunoreactivity as a Possible Diagnostic and Prognostic Marker of Thymic Carcinoma"],"prefix":"10.1620","volume":"246","author":[{"given":"Sumiko","family":"Maeda","sequence":"first","affiliation":[{"name":"Department of General Thoracic Surgery, Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshimasa","family":"Nakazato","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keitaro","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Toxicology, Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morimichi","family":"Nishihira","sequence":"additional","affiliation":[{"name":"Department of General Thoracic Surgery, Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of General Thoracic Surgery, Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Araki","sequence":"additional","affiliation":[{"name":"Department of General Thoracic Surgery, Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Karube","sequence":"additional","affiliation":[{"name":"Department of General Thoracic Surgery, Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of General Thoracic Surgery, Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Chida","sequence":"additional","affiliation":[{"name":"Department of General Thoracic Surgery, Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"622","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"Ahmad, U., Yao, X., Detterbeck, F., Huang, J., Antonicelli, A., Filosso, P.L., Ruffini, E., Travis, W., Jones, D.R., Zhan, Y., Lucchi, M. &amp; Rimner, A. (2015)  Thymic carcinoma outcomes and prognosis: results of an international analysis.  <i>J. Thorac. Cardiovasc. Surg<\/i>., 149, 95-100, 101 e101-102.","DOI":"10.1016\/j.jtcvs.2014.09.124"},{"key":"2","doi-asserted-by":"crossref","unstructured":"Hayashi, K., Jutabha, P., Maeda, S., Supak, Y., Ouchi, M., Endou, H., Fujita, T., Chida, M. &amp; Anzai, N. (2016)  LAT1 acts as a crucial transporter of amino acids in human thymic carcinoma cells.  <i>J. Pharmacol. Sci<\/i>., 132, 201-204.","DOI":"10.1016\/j.jphs.2016.07.006"},{"key":"3","doi-asserted-by":"crossref","unstructured":"Hishida, T., Nomura, S., Yano, M., Asamura, H., Yamashita, M., Ohde, Y., Kondo, K., Date, H., Okumura, M. &amp; Nagai, K.; Japanese Association for Research on the Thymus (JART)  (2016)  Long-term outcome and prognostic factors of surgically treated thymic carcinoma: results of 306 cases from a Japanese Nationwide Database Study.  <i>Eur. J. Cardiothorac. Surg<\/i>., 49, 835-841.","DOI":"10.1093\/ejcts\/ezv239"},{"key":"4","unstructured":"Hishima, T., Fukayama, M., Fujisawa, M., Hayashi, Y., Arai, K., Funata, N. &amp; Koike, M. (1994)  CD5 expression in thymic carcinoma.  <i>Am. J. Pathol<\/i>., 145, 268-275."},{"key":"5","doi-asserted-by":"crossref","unstructured":"Honjo, H., Kaira, K., Miyazaki, T., Yokobori, T., Kanai, Y., Nagamori, S., Oyama, T., Asao, T. &amp; Kuwano, H. (2016)  Clinicopathological significance of LAT1 and ASCT2 in patients with surgically resected esophageal squamous cell carcinoma.  <i>J. Surg. Oncol<\/i>., 113, 381-389.","DOI":"10.1002\/jso.24160"},{"key":"6","doi-asserted-by":"crossref","unstructured":"Kaira, K., Oriuchi, N., Imai, H., Shimizu, K., Yanagitani, N., Sunaga, N., Hisada, T., Ishizuka, T., Kanai, Y., Endou, H., Nakajima, T. &amp; Mori, M. (2009a)  L-type amino acid transporter 1 (LAT1) is frequently expressed in thymic carcinomas but is absent in thymomas.  <i>J. Surg. Oncol<\/i>., 99, 433-438.","DOI":"10.1002\/jso.21277"},{"key":"7","doi-asserted-by":"crossref","unstructured":"Kaira, K., Oriuchi, N., Imai, H., Shimizu, K., Yanagitani, N., Sunaga, N., Hisada, T., Ishizuka, T., Kanai, Y., Nakajima, T. &amp; Mori, M. (2009b)  Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in stage I pulmonary adenocarcinoma.  <i>Lung Cancer<\/i>, 66, 120-126.","DOI":"10.1016\/j.lungcan.2008.12.015"},{"key":"8","doi-asserted-by":"crossref","unstructured":"Kaira, K., Sunose, Y., Arakawa, K., Ogawa, T., Sunaga, N., Shimizu, K., Tominaga, H., Oriuchi, N., Itoh, H., Nagamori, S., Kanai, Y., Segawa, A., Furuya, M., Mori, M., Oyama, T., et al.  (2012)  Prognostic significance of L-type amino-acid transporter 1 expression in surgically resected pancreatic cancer.  <i>Br. J. Cancer<\/i>, 107, 632-638.","DOI":"10.1038\/bjc.2012.310"},{"key":"9","doi-asserted-by":"crossref","unstructured":"Kanai, Y., Segawa, H., Miyamoto, K., Uchino, H., Takeda, E. &amp; Endou, H. (1998)  Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98).  <i>J. Biol. Chem<\/i>., 273, 23629-23632.","DOI":"10.1074\/jbc.273.37.23629"},{"key":"10","doi-asserted-by":"crossref","unstructured":"Kojika, M., Ishii, G., Yoshida, J., Nishimura, M., Hishida, T., Ota, S.J., Murata, Y., Nagai, K. &amp; Ochiai, A. (2009)  Immunohistochemical differential diagnosis between thymic carcinoma and type B3 thymoma: diagnostic utility of hypoxic marker, GLUT-1, in thymic epithelial neoplasms.  <i>Mod. Pathol<\/i>., 22, 1341-1350.","DOI":"10.1038\/modpathol.2009.105"},{"key":"11","doi-asserted-by":"crossref","unstructured":"Li, J., Qiang, J., Chen, S.F., Wang, X., Fu, J. &amp; Chen, Y. (2013)  The impact of L-type amino acid transporter 1 (LAT1) in human hepatocellular carcinoma.  <i>Tumour Biol<\/i>., 34, 2977-2981.","DOI":"10.1007\/s13277-013-0861-5"},{"key":"12","doi-asserted-by":"crossref","unstructured":"Milkereit, R., Persaud, A., Vanoaica, L., Guetg, A., Verrey, F. &amp; Rotin, D. (2015)  LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation.  <i>Nat. Commun<\/i>., 6, 7250.","DOI":"10.1038\/ncomms8250"},{"key":"13","doi-asserted-by":"crossref","unstructured":"Morinaga, S., Sato, Y., Shimosato, Y., Sinkai, T. &amp; Tsuchiya, R. (1987)  Multiple thymic squamous cell carcinomas associated with mixed type thymoma.  <i>Am. J. Surg. Pathol<\/i>., 11, 982-988.","DOI":"10.1097\/00000478-198712000-00009"},{"key":"14","doi-asserted-by":"crossref","unstructured":"Nicklin, P., Bergman, P., Zhang, B., Triantafellow, E., Wang, H., Nyfeler, B., Yang, H., Hild, M., Kung, C., Wilson, C., Myer, V.E., MacKeigan, J.P., Porter, J.A., Wang, Y.K., Cantley, L.C.,  et al. (2009)  Bidirectional transport of amino acids regulates mTOR and autophagy.  <i>Cell<\/i>, 136, 521-534.","DOI":"10.1016\/j.cell.2008.11.044"},{"key":"15","doi-asserted-by":"crossref","unstructured":"Omatsu, M., Kunimura, T., Mikogami, T., Hamatani, S., Shiokawa, A., Masunaga, A., Kitami, A., Suzuki, T., Kadokura, M. &amp; Morohoshi, T. (2012)  Immunohistochemical analysis of thymic carcinoma focusing on the possibility of molecular targeted and hormonal therapies.  <i>Gen. Thorac. Cardiovasc. Surg<\/i>., 60, 803-810.","DOI":"10.1007\/s11748-012-0160-x"},{"key":"16","doi-asserted-by":"crossref","unstructured":"Pan, C.C., Chen, P.C. &amp; Chiang, H. (2004)  KIT (CD117) is frequently overexpressed in thymic carcinomas but is absent in thymomas.  <i>J. Pathol<\/i>., 202, 375-381.","DOI":"10.1002\/path.1514"},{"key":"17","doi-asserted-by":"crossref","unstructured":"Toyoda, M., Kaira, K., Ohshima, Y., Ishioka, N.S., Shino, M., Sakakura, K., Takayasu, Y., Takahashi, K., Tominaga, H., Oriuchi, N., Nagamori, S., Kanai, Y., Oyama, T. &amp; Chikamatsu, K. (2014)  Prognostic significance of amino-acid transporter expression (LAT1, ASCT2, and xCT) in surgically resected tongue cancer.  <i>Br. J. Cancer<\/i>, 110, 2506-2513.","DOI":"10.1038\/bjc.2014.178"},{"key":"18","doi-asserted-by":"crossref","unstructured":"Yanagida, O., Kanai, Y., Chairoungdua, A., Kim, D. K., Segawa, H., Nii, T., Cha, S. H., Matsuo, H., Fukushima, J., Fukasawa, Y., Tani, Y., Taketani, Y., Uchino, H., Kim, J.Y., Inatomi, J.,  et al. (2001)  Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines.  <i>Biochim. Biophys. Acta<\/i>, 1514, 291-302.","DOI":"10.1016\/S0005-2736(01)00384-4"}],"container-title":["The Tohoku Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/tjem\/246\/3\/246_167\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,11,17]],"date-time":"2018-11-17T05:21:38Z","timestamp":1542432098000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/tjem\/246\/3\/246_167\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1620\/tjem.246.167","relation":{},"ISSN":["0040-8727","1349-3329"],"issn-type":[{"value":"0040-8727","type":"print"},{"value":"1349-3329","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]}}}