{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T12:05:10Z","timestamp":1780401910029,"version":"3.54.1"},"reference-count":84,"publisher":"Zhejiang University Press","issue":"11","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"National Basic Research Program (973) of China","award":["2014CB965100"],"award-info":[{"award-number":["2014CB965100"]}]},{"name":"National Basic Research Program (973) of China","award":["2014CB965102"],"award-info":[{"award-number":["2014CB965102"]}]},{"name":"National Basic Research Program (973) of China","award":["2014CB965103"],"award-info":[{"award-number":["2014CB965103"]}]},{"name":"National High-Tech R & D Program (863) of China","award":["2015AA020922"],"award-info":[{"award-number":["2015AA020922"]}]},{"name":"National Natural Science Foundation of China","award":["81320108003"],"award-info":[{"award-number":["81320108003"]}]},{"name":"National Natural Science Foundation of China","award":["31371498"],"award-info":[{"award-number":["31371498"]}]},{"name":"National Natural Science Foundation of China","award":["81570233"],"award-info":[{"award-number":["81570233"]}]}],"content-domain":{"domain":["springerlink.com","zju.edu.cn"],"crossmark-restriction":true},"short-container-title":["J. Zhejiang Univ. Sci. B"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1631\/jzus.b1600253","type":"journal-article","created":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T23:06:57Z","timestamp":1479164817000},"page":"821-830","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Roles of SIRT3 in heart failure: from bench to bedside","SIRT3 \u5728\u5fc3\u8870\u4e2d\u7684\u4f5c\u7528: \u4ece\u57fa\u7840\u5230\u4e34\u5e8a"],"prefix":"10.1631","volume":"17","author":[{"given":"De-xing","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian-bao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-chao","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-an","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"635","published-online":{"date-parts":[[2016,11,16]]},"reference":[{"issue":"3","key":"199_CR1","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1002\/cbf.1449","volume":"26","author":"I.K. Adiga","year":"2008","unstructured":"Adiga, I.K., Nair, R.R., 2008. Multiple signaling pathways coordinately mediate reactive oxygen species dependent cardiomyocyte hypertrophy. Cell Biochem. Funct., 26(3): 346\u2013351. http:\/\/dx.doi.org\/10.1002\/cbf.1449.","journal-title":"Cell Biochem. Funct."},{"issue":"38","key":"199_CR2","doi-asserted-by":"publisher","first-page":"14447","DOI":"10.1073\/pnas.0803790105","volume":"105","author":"B.H. Ahn","year":"2008","unstructured":"Ahn, B.H., Kim, H.S., Song, S., et al., 2008. A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. PNAS, 105(38):14447\u201314452. http:\/\/dx.doi.org\/10.1073\/pnas.0803790105","journal-title":"PNAS"},{"issue":"1","key":"199_CR3","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1053\/snep.2001.18367","volume":"21","author":"A. Al-Ahmad","year":"2001","unstructured":"Al-Ahmad, A., Sarnak, M.J., Salem, D.N., 2001. Cause and management of heart failure in patients with chronic renal disease. Semin. Nephrol., 21(1):3\u201312.","journal-title":"Semin. Nephrol."},{"issue":"2","key":"199_CR4","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1016\/j.ygeno.2004.11.003","volume":"85","author":"D. Bellizzi","year":"2005","unstructured":"Bellizzi, D., Rose, G., Cavalcante, P., et al., 2005. A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages. Genomics, 85(2):258\u2013263. http:\/\/dx.doi.org\/10.1016\/j.ygeno.2004.11.003","journal-title":"Genomics"},{"issue":"3","key":"199_CR5","doi-asserted-by":"publisher","first-page":"H1227","DOI":"10.1152\/ajpheart.01162.2006","volume":"292","author":"C. Berndt","year":"2007","unstructured":"Berndt, C., Lillig, C.H., Holmgren, A., 2007. Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system. Am. J. Physiol. Heart Circ. Physiol., 292(3):H1227\u2013H1236. http:\/\/dx.doi.org\/10.1152\/ajpheart.01162.2006","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"4","key":"199_CR6","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/0002-9343(54)90365-4","volume":"16","author":"R.J. Bing","year":"1954","unstructured":"Bing, R.J., Siegel, A., Ungar, I., et al., 1954. Metabolism of the human heart. II. Studies on fat, ketone and amino acid metabolism. Am. J. Med., 16(4):504\u2013515. http:\/\/dx.doi.org\/10.1016\/0002-9343(54)90365-4","journal-title":"Am. J. Med."},{"key":"199_CR7","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.yjmcc.2015.03.017","volume":"84","author":"T. Bochaton","year":"2015","unstructured":"Bochaton, T., Crola-Da-Silva, C., Pillot, B., et al., 2015. Inhibition of myocardial reperfusion injury by ischemic postconditioning requires sirtuin 3-mediated deacetylation of cyclophilin D. J. Mol. Cell. Cardiol., 84:61\u201369. http:\/\/dx.doi.org\/10.1016\/j.yjmcc.2015.03.017","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"6","key":"199_CR8","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1161\/01.CIR.0000155257.33485.6D","volume":"111","author":"A. Borbely","year":"2005","unstructured":"Borbely, A., van der Velden, J., Papp, Z., et al., 2005. Cardiomyocyte stiffness in diastolic heart failure. Circulation, 111(6):774\u2013781. http:\/\/dx.doi.org\/10.1161\/01.CIR.0000155257.33485.6D","journal-title":"Circulation"},{"issue":"1","key":"199_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jchf.2012.10.002","volume":"1","author":"E. Braunwald","year":"2013","unstructured":"Braunwald, E., 2013. Heart failure. JACC Heart Fail, 1(1): 1\u201320. http:\/\/dx.doi.org\/10.1016\/j.jchf.2012.10.002","journal-title":"JACC Heart Fail"},{"issue":"2","key":"199_CR10","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/s10741-016-9533-z","volume":"21","author":"A. Briasoulis","year":"2016","unstructured":"Briasoulis, A., Androulakis, E., Christophides, T., et al., 2016. The role of inflammation and cell death in the pathogenesis, progression and treatment of heart failure. Heart Fail Rev., 21(2):169\u2013176. http:\/\/dx.doi.org\/10.1007\/s10741-016-9533-z","journal-title":"Heart Fail Rev."},{"issue":"5","key":"199_CR11","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1111\/j.1582-4934.2008.00620.x","volume":"13","author":"J. Cai","year":"2009","unstructured":"Cai, J., Yi, F.F., Bian, Z.Y., et al., 2009. Crocetin protects against cardiac hypertrophy by blocking MEK-ERK1\/2 signalling pathway. J. Cell. Mol. Med., 13(5):909\u2013925. http:\/\/dx.doi.org\/10.1111\/j.1582-4934.2008.00620.x","journal-title":"J. Cell. Mol. Med."},{"issue":"2","key":"199_CR12","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1016\/j.bbrc.2012.11.066","volume":"430","author":"C.J. Chen","year":"2013","unstructured":"Chen, C.J., Fu, Y.C., Yu, W., et al., 2013. SIRT3 protects cardiomyocytes from oxidative stress-mediated cell death by activating NF-?B. Biochem. Biophys. Res. Commun., 430(2):798\u2013803. http:\/\/dx.doi.org\/10.1016\/j.bbrc.2012.11.066","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"15","key":"199_CR13","doi-asserted-by":"publisher","first-page":"1669","DOI":"10.1001\/jama.2011.1474","volume":"306","author":"J. Chen","year":"2011","unstructured":"Chen, J., Normand, S.L., Wang, Y., et al., 2011. National and regional trends in heart failure hospitalization and mortality rates for medicare beneficiaries, 1998\u20132008. JAMA, 306(15):1669\u20131678. http:\/\/dx.doi.org\/10.1001\/jama.2011.1474","journal-title":"JAMA"},{"issue":"5","key":"199_CR14","doi-asserted-by":"publisher","first-page":"H424","DOI":"10.1152\/ajpheart.00454.2014","volume":"308","author":"T. Chen","year":"2015","unstructured":"Chen, T., Li, J., Liu, J., et al., 2015a. Activation of SIRT3 by resveratrol ameliorates cardiac fibrosis and improves cardiac function via the TGF-\u03b2\/Smad3 pathway. Am. J. Physiol. Heart Circ. Physiol., 308(5):H424\u2013H434. http:\/\/dx.doi.org\/10.1152\/ajpheart.00454.2014","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"3","key":"199_CR15","doi-asserted-by":"publisher","first-page":"e0118909","DOI":"10.1371\/journal.pone.0118909","volume":"10","author":"T. Chen","year":"2015","unstructured":"Chen, T., Liu, J., Li, N., et al., 2015b. Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD. PLOS ONE, 10(3): e0118909. http:\/\/dx.doi.org\/10.1371\/journal.pone.0118909","journal-title":"PLOS ONE"},{"issue":"1","key":"199_CR16","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/j.cardiores.2005.07.012","volume":"69","author":"M.P. Cole","year":"2006","unstructured":"Cole, M.P., Chaiswing, L., Oberley, T.D., et al., 2006. The protective roles of nitric oxide and superoxide dismutase in adriamycin-induced cardiotoxicity. Cardiovasc. Res., 69(1):186\u2013197. http:\/\/dx.doi.org\/10.1016\/j.cardiores.2005.07.012","journal-title":"Cardiovasc. Res."},{"issue":"27","key":"199_CR17","doi-asserted-by":"publisher","first-page":"10042","DOI":"10.1073\/pnas.0400593101","volume":"101","author":"H. Daitoku","year":"2004","unstructured":"Daitoku, H., Hatta, M., Matsuzaki, H., et al., 2004. Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity. PNAS, 101(27):10042\u201310047. http:\/\/dx.doi.org\/10.1073\/pnas.0400593101","journal-title":"PNAS"},{"issue":"4","key":"199_CR18","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1016\/j.cmet.2015.03.007","volume":"21","author":"K.E. Dittenhafer-Reed","year":"2015","unstructured":"Dittenhafer-Reed, K.E., Richards, A.L., Fan, J., et al., 2015. SIRT3 mediates multi-tissue coupling for metabolic fuel switching. Cell Metab., 21(4):637\u2013646. http:\/\/dx.doi.org\/10.1016\/j.cmet.2015.03.007","journal-title":"Cell Metab."},{"issue":"11","key":"199_CR19","first-page":"685","volume":"377","author":"R. Eckner","year":"1996","unstructured":"Eckner, R., 1996. p300 and CBP as transcriptional regulators and targets of oncogenic events. Biol. Chem., 377(11): 685\u2013688.","journal-title":"Biol. Chem."},{"issue":"7255","key":"199_CR20","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1038\/nature08197","volume":"460","author":"T. Finkel","year":"2009","unstructured":"Finkel, T., Deng, C.X., Mostoslavsky, R., 2009. Recent progress in the biology and physiology of sirtuins. Nature, 460(7255):587\u2013591. http:\/\/dx.doi.org\/10.1038\/nature08197","journal-title":"Nature"},{"issue":"1","key":"199_CR21","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1007\/s10741-010-9169-3","volume":"16","author":"M.S. Gandhi","year":"2011","unstructured":"Gandhi, M.S., Kamalov, G., Shahbaz, A.U., et al., 2011. Cellular and molecular pathways to myocardial necrosis and replacement fibrosis. Heart Fail. Rev., 16(1):23\u201334. http:\/\/dx.doi.org\/10.1007\/s10741-010-9169-3","journal-title":"Heart Fail. Rev."},{"key":"199_CR22","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.ijcard.2015.01.073","volume":"184","author":"C. Greco","year":"2015","unstructured":"Greco, C., Rosato, S., D\u2019Errigo, P., et al., 2015. Trends in mortality and heart failure after acute myocardial infarction in Italy from 2001 to 2011. Int. J. Cardiol., 184:115\u2013121. http:\/\/dx.doi.org\/10.1016\/j.ijcard.2015.01.073","journal-title":"Int. J. Cardiol."},{"issue":"5","key":"199_CR23","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1161\/CIRCRESAHA.108.186288","volume":"104","author":"J. Guo","year":"2009","unstructured":"Guo, J., Gertsberg, Z., Ozgen, N., et al., 2009. p66Shc links a1-adrenergic receptors to a reactive oxygen speciesdependent AKT-FOXO3A phosphorylation pathway in cardiomyocytes. Circ. Res., 104(5):660\u2013669. http:\/\/dx.doi.org\/10.1161\/CIRCRESAHA.108.186288","journal-title":"Circ. Res."},{"issue":"12","key":"199_CR24","doi-asserted-by":"publisher","first-page":"914","DOI":"10.18632\/aging.100252","volume":"2","author":"A.V. Hafner","year":"2010","unstructured":"Hafner, A.V., Dai, J., Gomes, A.P., et al., 2010. Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy. Aging (Albany NY), 2(12):914\u2013923. http:\/\/dx.doi.org\/10.18632\/aging.100252","journal-title":"Aging (Albany NY)"},{"issue":"6","key":"199_CR25","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1111\/j.1440-1843.2010.01776.x","volume":"15","author":"J.D. Hannink","year":"2010","unstructured":"Hannink, J.D., van Helvoort, H.A., Dekhuijzen, P.N., et al., 2010. Heart failure and COPD: partners in crime? Respirology, 15(6):895\u2013901. http:\/\/dx.doi.org\/10.1111\/j.1440-1843.2010.01776.x","journal-title":"Respirology"},{"issue":"7","key":"199_CR26","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1056\/NEJMoa1110186","volume":"366","author":"D.S. Herman","year":"2012","unstructured":"Herman, D.S., Lam, L., Taylor, M.R., et al., 2012. Truncations of titin causing dilated cardiomyopathy. N. Engl. J. Med., 366(7):619\u2013628. http:\/\/dx.doi.org\/10.1056\/NEJMoa1110186","journal-title":"N. Engl. J. Med."},{"issue":"7285","key":"199_CR27","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1038\/nature08778","volume":"464","author":"M.D. Hirschey","year":"2010","unstructured":"Hirschey, M.D., Shimazu, T., Goetzman, E., et al., 2010. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature, 464(7285): 121\u2013125. http:\/\/dx.doi.org\/10.1038\/nature08778","journal-title":"Nature"},{"issue":"4","key":"199_CR28","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1111\/j.1745-7254.2006.00300.x","volume":"27","author":"T.P. Hu","year":"2006","unstructured":"Hu, T.P., Xu, F.P., Li, Y.J., et al., 2006. Simvastatin inhibits leptin-induced hypertrophy in cultured neonatal rat cardiomyocytes. Acta Pharmacol. Sin., 27(4):419\u2013422. http:\/\/dx.doi.org\/10.1111\/j.1745-7254.2006.00300.x","journal-title":"Acta Pharmacol. Sin."},{"issue":"8","key":"199_CR29","first-page":"629","volume":"12","author":"X.Q. Hu","year":"2014","unstructured":"Hu, X.Q., Cheng, J., Tang, B., et al., 2014. Clinical effect of postconditioning in ST-elevation myocardial infarction patients treated with primary percutaneous coronary intervention: a meta-analysis of randomized controlled trials. J. Zhejiang Univ.-Sci. B (Biomed. & Biotechnol.), 12(8):629\u2013632. http:\/\/dx.doi.org\/10.1631\/jzus.B1101010","journal-title":"J. Zhejiang Univ.-Sci. B (Biomed. & Biotechnol.)"},{"issue":"5","key":"199_CR30","doi-asserted-by":"publisher","first-page":"e000172","DOI":"10.1161\/JAHA.113.000172","volume":"2","author":"J. Hung","year":"2013","unstructured":"Hung, J., Teng, T.H., Finn, J., et al., 2013. Trends from 1996 to 2007 in incidence and mortality outcomes of heart failure after acute myocardial infarction: a population-based study of 20 812 patients with first acute myocardial infarction in Western Australia. J. Am. Heart Assoc., 2(5): e000172. http:\/\/dx.doi.org\/10.1161\/JAHA.113.000172","journal-title":"J. Am. Heart Assoc."},{"issue":"10","key":"199_CR31","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1016\/j.cardfail.2007.07.007","volume":"13","author":"M. Kamalesh","year":"2007","unstructured":"Kamalesh, M., 2007. Heart failure in diabetes and related conditions. J. Card. Fail., 13(10):861\u2013873. http:\/\/dx.doi.org\/10.1016\/j.cardfail.2007.07.007","journal-title":"J. Card. Fail."},{"issue":"16","key":"199_CR32","doi-asserted-by":"publisher","first-page":"1922","DOI":"10.1161\/CIRCULATIONAHA.106.620765","volume":"113","author":"A.M. Katz","year":"2006","unstructured":"Katz, A.M., Zile, M.R., 2006. New molecular mechanism in diastolic heart failure. Circulation, 113(16):1922\u20131925. http:\/\/dx.doi.org\/10.1161\/circulationaha.106.620765","journal-title":"Circulation"},{"issue":"1","key":"199_CR33","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.ccr.2009.11.023","volume":"17","author":"H.S. Kim","year":"2010","unstructured":"Kim, H.S., Patel, K., Muldoon-Jacobs, K., et al., 2010. SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer Cell, 17(1):41\u201352. http:\/\/dx.doi.org\/10.1016\/j.ccr.2009.11.023","journal-title":"Cancer Cell"},{"issue":"1","key":"199_CR34","doi-asserted-by":"publisher","first-page":"112","DOI":"10.18433\/J3XG7T","volume":"18","author":"M.S. Klishadi","year":"2015","unstructured":"Klishadi, M.S., Zarei, F., Hejazian, S.H., et al., 2015. Losartan protects the heart against ischemia reperfusion injury: sirtuin3 involvement. J. Pharm. Pharm. Sci., 18(1):112\u2013123. http:\/\/dx.doi.org\/10.18433\/J3XG7T","journal-title":"J. Pharm. Pharm. Sci."},{"issue":"2","key":"199_CR35","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1038\/nrcardio.2015.205","volume":"13","author":"L. Kober","year":"2016","unstructured":"Kober, L., 2016. Heart failure in 2015: better results from prevention than from additional treatment. Nat. Rev. Cardiol., 13(2):75\u201377. http:\/\/dx.doi.org\/10.1038\/nrcardio.2015.205","journal-title":"Nat. Rev. Cardiol."},{"issue":"4","key":"199_CR36","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1007\/s00395-015-0493-6","volume":"110","author":"C. Koentges","year":"2015","unstructured":"Koentges, C., Pfeil, K., Schnick, T., et al., 2015. SIRT3 deficiency impairs mitochondrial and contractile function in the heart. Basic Res. Cardiol., 110(4):36. http:\/\/dx.doi.org\/10.1007\/s00395-015-0493-6","journal-title":"Basic Res. Cardiol."},{"issue":"7","key":"199_CR37","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1161\/ATVBAHA.111.224915","volume":"32","author":"K. Konstantinidis","year":"2012","unstructured":"Konstantinidis, K., Whelan, R.S., Kitsis, R.N., 2012. Mechanisms of cell death in heart disease. Arterioscler. Thromb. Vasc. Biol., 32(7):1552\u20131562. http:\/\/dx.doi.org\/10.1161\/ATVBAHA.111.224915","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"11","key":"199_CR38","doi-asserted-by":"publisher","first-page":"2933","DOI":"10.2337\/db08-0349","volume":"57","author":"I.R. Lanza","year":"2008","unstructured":"Lanza, I.R., Short, D.K., Short, K.R., et al., 2008. Endurance exercise as a countermeasure for aging. Diabetes, 57(11): 2933\u20132942. http:\/\/dx.doi.org\/10.2337\/db08-0349","journal-title":"Diabetes"},{"issue":"6","key":"199_CR39","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.cmet.2006.04.013","volume":"3","author":"C. Lerin","year":"2006","unstructured":"Lerin, C., Rodgers, J.T., Kalume, D.E., et al., 2006. GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1a. Cell Metab., 3(6):429\u2013438. http:\/\/dx.doi.org\/10.1016\/j.cmet.2006.04.013","journal-title":"Cell Metab."},{"issue":"10","key":"199_CR40","doi-asserted-by":"publisher","first-page":"1756","DOI":"10.1016\/j.freeradbiomed.2006.01.005","volume":"40","author":"H.L. Li","year":"2006","unstructured":"Li, H.L., Huang, Y., Zhang, C.N., et al., 2006. Epigallocathechin-3 gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways. Free Radic. Biol. Med., 40(10):1756\u20131775. http:\/\/dx.doi.org\/10.1016\/j.freeradbiomed.2006.01.005","journal-title":"Free Radic. Biol. Med."},{"issue":"3","key":"199_CR41","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/0002-9149(71)90303-1","volume":"27","author":"G.E. Lindenmayer","year":"1971","unstructured":"Lindenmayer, G.E., Sordahl, L.A., Harigaya, S., et al., 1971. Some biochemical studies on subcellular systems isolated from fresh recipient human cardiac tissue obtained during transplantation. Am. J. Cardiol., 27(3):277\u2013283. http:\/\/dx.doi.org\/10.1016\/0002-9149(71)90303-1","journal-title":"Am. J. Cardiol."},{"issue":"24","key":"199_CR42","doi-asserted-by":"publisher","first-page":"8807","DOI":"10.1128\/MCB.01636-07","volume":"27","author":"D.B. Lombard","year":"2007","unstructured":"Lombard, D.B., Alt, F.W., Cheng, H.L., et al., 2007. Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Mol. Cell. Biol., 27(24): 8807\u20138814. http:\/\/dx.doi.org\/10.1128\/MCB.01636-07","journal-title":"Mol. Cell. Biol."},{"issue":"2","key":"199_CR43","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1007\/s00395-012-0245-9","volume":"107","author":"J.M. Lorenzen","year":"2012","unstructured":"Lorenzen, J.M., Martino, F., Thum, T., 2012. Epigenetic modifications in cardiovascular disease. Basic Res. Cardiol., 107(2):245. http:\/\/dx.doi.org\/10.1007\/s00395-012-0245-9","journal-title":"Basic Res. Cardiol."},{"issue":"34","key":"199_CR44","doi-asserted-by":"publisher","first-page":"2267","DOI":"10.1093\/eurheartj\/ehv348","volume":"36","author":"T.F. L\u00fcscher","year":"2015","unstructured":"L\u00fcscher, T.F., 2015. Risk factors for and management of heart failure. Eur. Heart J., 36(34):2267\u20132269. http:\/\/dx.doi.org\/10.1093\/eurheartj\/ehv348","journal-title":"Eur. Heart J."},{"issue":"4","key":"199_CR45","doi-asserted-by":"publisher","first-page":"H459","DOI":"10.1152\/ajpheart.00936.2012","volume":"305","author":"E. Marzetti","year":"2013","unstructured":"Marzetti, E., Csiszar, A., Dutta, D., et al., 2013. Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics. Am. J. Physiol. Heart Circ. Physiol., 305(4): H459\u2013H476. http:\/\/dx.doi.org\/10.1152\/ajpheart.00936.2012","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"3","key":"199_CR46","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1172\/JCI24351","volume":"115","author":"H. Morita","year":"2005","unstructured":"Morita, H., Seidman, J., Seidman, C.E., 2005. Genetic causes of human heart failure. J. Clin. Invest., 115(3):518\u2013526. http:\/\/dx.doi.org\/10.1172\/JCI24351","journal-title":"J. Clin. Invest."},{"issue":"4","key":"199_CR47","doi-asserted-by":"publisher","first-page":"e38","DOI":"10.1161\/CIR.0000000000000350","volume":"133","author":"D. Mozaffarian","year":"2016","unstructured":"Mozaffarian, D., Benjamin, E.J., Go, A.S., et al., 2016. Heart disease and stroke statistics\u20142016 update: a report from the American Heart Association. Circulation, 133(4): e38\u2013e360. http:\/\/dx.doi.org\/10.1161\/CIR.0000000000000350","journal-title":"Circulation"},{"issue":"2","key":"199_CR48","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1152\/physrev.00024.2007","volume":"88","author":"E. Murphy","year":"2008","unstructured":"Murphy, E., Steenbergen, C., 2008. Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury. Physiol. Rev., 88(2):581\u2013609. http:\/\/dx.doi.org\/10.1152\/physrev.00024.2007","journal-title":"Physiol. Rev."},{"issue":"14","key":"199_CR49","doi-asserted-by":"publisher","first-page":"1742","DOI":"10.1093\/eurheartj\/ehs135","volume":"33","author":"T. Ohtani","year":"2012","unstructured":"Ohtani, T., Mohammed, S.F., Yamamoto, K., et al., 2012. Diastolic stiffness as assessed by diastolic wall strain is associated with adverse remodelling and poor outcomes in heart failure with preserved ejection fraction. Eur. Heart J., 33(14):1742\u20131749. http:\/\/dx.doi.org\/10.1093\/eurheartj\/ehs135","journal-title":"Eur. Heart J."},{"issue":"16","key":"199_CR50","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1056\/NEJM199704173361603","volume":"336","author":"G. Olivetti","year":"1997","unstructured":"Olivetti, G., Abbi, R., Quaini, F., et al., 1997. Apoptosis in the failing human heart. N. Engl. J. Med., 336(16):1131\u20131141. http:\/\/dx.doi.org\/10.1056\/NEJM199704173361603","journal-title":"N. Engl. J. Med."},{"issue":"21","key":"199_CR51","doi-asserted-by":"publisher","first-page":"13653","DOI":"10.1073\/pnas.222538099","volume":"99","author":"P. Onyango","year":"2002","unstructured":"Onyango, P., Celic, I., McCaffery, J.M., et al., 2002. SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. PNAS, 99(21): 13653\u201313658. http:\/\/dx.doi.org\/10.1073\/pnas.222538099","journal-title":"PNAS"},{"key":"199_CR52","doi-asserted-by":"publisher","first-page":"6656","DOI":"10.1038\/ncomms7656","volume":"6","author":"V.B. Pillai","year":"2015","unstructured":"Pillai, V.B., Samant, S., Sundaresan, N.R., et al., 2015. Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3. Nat. Commun., 6:6656. http:\/\/dx.doi.org\/10.1038\/ncomms7656","journal-title":"Nat. Commun."},{"issue":"2","key":"199_CR53","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/S0008-6363(98)00033-9","volume":"38","author":"H.M. Piper","year":"1998","unstructured":"Piper, H.M., Garcia-Dorado, D., Ovize, M., 1998. A fresh look at reperfusion injury. Cardiovasc. Res., 38(2):291\u2013300. http:\/\/dx.doi.org\/10.1016\/S0008-6363(98)00033-9","journal-title":"Cardiovasc. Res."},{"issue":"11","key":"199_CR54","doi-asserted-by":"publisher","first-page":"2597","DOI":"10.1111\/jcmm.12664","volume":"19","author":"M. Richter","year":"2015","unstructured":"Richter, M., Kostin, S., 2015. The failing human heart is characterized by decreased numbers of telocytes as result of apoptosis and altered extracellular matrix composition. J. Cell. Mol. Med., 19(11):2597\u20132606. http:\/\/dx.doi.org\/10.1111\/jcmm.12664","journal-title":"J. Cell. Mol. Med."},{"issue":"10","key":"199_CR55","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1016\/S0531-5565(03)00209-2","volume":"38","author":"G. Rose","year":"2003","unstructured":"Rose, G., Dato, S., Altomare, K., et al., 2003. Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly. Exp. Gerontol., 38(10):1065\u20131070.","journal-title":"Exp. Gerontol."},{"issue":"3","key":"199_CR56","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1161\/01.RES.56.3.377","volume":"56","author":"J. Schaper","year":"1985","unstructured":"Schaper, J., Meiser, E., Stammler, G., 1985. Ultrastructural morphometric analysis of myocardium from dogs, rats, hamsters, mice, and from human hearts. Circ. Res., 56(3): 377\u2013391. http:\/\/dx.doi.org\/10.1161\/01.RES.56.3.377","journal-title":"Circ. Res."},{"issue":"8","key":"199_CR57","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1101\/gad.1527307","volume":"21","author":"M.B. Scher","year":"2007","unstructured":"Scher, M.B., Vaquero, A., Reinberg, D., 2007. SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress. Genes Dev., 21(8):920\u2013928. http:\/\/dx.doi.org\/10.1101\/gad.1527307","journal-title":"Genes Dev."},{"issue":"2","key":"199_CR58","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.cmet.2007.11.006","volume":"7","author":"B. Schwer","year":"2008","unstructured":"Schwer, B., Verdin, E., 2008. Conserved metabolic regulatory functions of sirtuins. Cell Metab., 7(2):104\u2013112. http:\/\/dx.doi.org\/10.1016\/j.cmet.2007.11.006","journal-title":"Cell Metab."},{"issue":"2","key":"199_CR59","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1021\/cb100218d","volume":"6","author":"B.C. Smith","year":"2011","unstructured":"Smith, B.C., Settles, B., Hallows, W.C., et al., 2011. SIRT3 substrate specificity determined by peptide arrays and machine learning. ACS Chem. Biol., 6(2):146\u2013157. http:\/\/dx.doi.org\/10.1021\/cb100218d","journal-title":"ACS Chem. Biol."},{"issue":"5","key":"199_CR60","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1016\/j.cell.2010.10.002","volume":"143","author":"S. Someya","year":"2010","unstructured":"Someya, S., Yu, W., Hallows, W.C., et al., 2010. Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell, 143(5):802\u2013812. http:\/\/dx.doi.org\/10.1016\/j.cell.2010.10.002","journal-title":"Cell"},{"issue":"3","key":"199_CR61","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1152\/ajplegacy.1973.224.3.497","volume":"224","author":"L.A. Sordahl","year":"1973","unstructured":"Sordahl, L.A., McCollum, W.B., Wood, W.G., et al., 1973. Mitochondria and sarcoplasmic reticulum function in cardiac hypertrophy and failure. Am. J. Physiol., 224(3): 497\u2013502.","journal-title":"Am. J. Physiol."},{"issue":"3","key":"199_CR62","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1161\/01.RES.21.3.341","volume":"21","author":"J.F. Spann","year":"1967","unstructured":"Spann, J.F., Buccino, R.A., Sonnenblick, E.H., et al., 1967. Contractile state of cardiac muscle obtained from cats with experimentally produced ventricular hypertrophy and heart failure. Circ. Res., 21(3):341\u2013354. http:\/\/dx.doi.org\/10.1161\/01.RES.21.3.341","journal-title":"Circ. Res."},{"issue":"2","key":"199_CR63","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1023\/A:1015320423577","volume":"7","author":"W.C. Stanley","year":"2002","unstructured":"Stanley, W.C., Chandler, M.P., 2002. Energy metabolism in the normal and failing heart: potential for therapeutic interventions. Heart Fail. Rev., 7(2):115\u2013130. http:\/\/dx.doi.org\/10.1023\/A:1015320423577","journal-title":"Heart Fail. Rev."},{"issue":"20","key":"199_CR64","doi-asserted-by":"publisher","first-page":"6384","DOI":"10.1128\/MCB.00426-08","volume":"28","author":"N.R. Sundaresan","year":"2008","unstructured":"Sundaresan, N.R., Samant, S.A., Pillai, V.B., et al., 2008. SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol. Cell. Biol., 28(20):6384\u20136401. http:\/\/dx.doi.org\/10.1128\/MCB.00426-08","journal-title":"Mol. Cell. Biol."},{"issue":"9","key":"199_CR65","first-page":"2758","volume":"119","author":"N.R. Sundaresan","year":"2009","unstructured":"Sundaresan, N.R., Gupta, M., Kim, G., et al., 2009. Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. J. Clin. Invest., 119(9):2758\u20132771. http:\/\/dx.doi.org\/10.1172\/JCI39162","journal-title":"J. Clin. Invest."},{"issue":"2","key":"199_CR66","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/0146-2806(94)90008-6","volume":"19","author":"H. Taegtmeyer","year":"1994","unstructured":"Taegtmeyer, H., 1994. Energy metabolism of the heart: from basic concepts to clinical applications. Curr. Probl. Cardiol., 19(2):59\u2013113. http:\/\/dx.doi.org\/10.1016\/0146-2806(94)90008-6","journal-title":"Curr. Probl. Cardiol."},{"issue":"44","key":"199_CR67","doi-asserted-by":"publisher","first-page":"29730","DOI":"10.1074\/jbc.M805514200","volume":"283","author":"W.Q. Tan","year":"2008","unstructured":"Tan, W.Q., Wang, K., Lv, D.Y., et al., 2008. Foxo3a inhibits cardiomyocyte hypertrophy through transactivating catalase. J. Biol. Chem., 283(44):29730\u201329739. http:\/\/dx.doi.org\/10.1074\/jbc.M805514200","journal-title":"J. Biol. Chem."},{"issue":"10","key":"199_CR68","doi-asserted-by":"publisher","first-page":"2347","DOI":"10.1253\/circj.CJ-14-0893","volume":"78","author":"J.A. Towbin","year":"2014","unstructured":"Towbin, J.A., 2014. Inherited cardiomyopathies. Circ. J., 78(10):2347\u20132356. http:\/\/dx.doi.org\/10.1253\/circj.CJ-14-0893","journal-title":"Circ. J."},{"issue":"40","key":"199_CR69","doi-asserted-by":"publisher","first-page":"2696","DOI":"10.1093\/eurheartj\/ehv428","volume":"36","author":"N. Townsend","year":"2015","unstructured":"Townsend, N., Nichols, M., Scarborough, P., et al., 2015. Cardiovascular disease in Europe\u2014epidemiological update 2015. Eur. Heart J., 36(40):2696\u20132705. http:\/\/dx.doi.org\/10.1093\/eurheartj\/ehv428","journal-title":"Eur. Heart J."},{"key":"199_CR70","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.freeradbiomed.2013.05.002","volume":"63","author":"A.H. Tseng","year":"2013","unstructured":"Tseng, A.H., Shieh, S.S., Wang, D.L., 2013. SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage. Free Radic. Biol. Med., 63:222\u2013234. http:\/\/dx.doi.org\/10.1016\/j.freeradbiomed.2013.05.002","journal-title":"Free Radic. Biol. Med."},{"issue":"4","key":"199_CR71","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1016\/j.jacc.2006.02.075","volume":"48","author":"V.P. Empel van","year":"2006","unstructured":"van Empel, V.P., Bertrand, A.T., van Oort, R.J., et al., 2006. EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant. J. Am. Coll. Cardiol., 48(4):824\u2013832. http:\/\/dx.doi.org\/10.1016\/j.jacc.2006.02.075","journal-title":"J. Am. Coll. Cardiol."},{"issue":"20","key":"199_CR72","doi-asserted-by":"publisher","first-page":"2057","DOI":"10.1161\/CIRCULATIONAHA.108.784215","volume":"118","author":"R.S. Velagaleti","year":"2008","unstructured":"Velagaleti, R.S., Pencina, M.J., Murabito, J.M., et al., 2008. Long-term trends in the incidence of heart failure after myocardial infarction. Circulation, 118(20):2057\u20132062. http:\/\/dx.doi.org\/10.1161\/circulationaha.108.784215","journal-title":"Circulation"},{"issue":"6","key":"199_CR73","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1007\/s11906-012-0305-4","volume":"14","author":"H.E. Verdejo","year":"2012","unstructured":"Verdejo, H.E., del Campo, A., Troncoso, R., et al., 2012. Mitochondria, myocardial remodeling, and cardiovascular disease. Curr. Hypertens. Rep., 14(6):532\u2013539. http:\/\/dx.doi.org\/10.1007\/s11906-012-0305-4","journal-title":"Curr. Hypertens. Rep."},{"issue":"1","key":"199_CR74","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1161\/01.HYP.0000250468.02084.ce","volume":"49","author":"S. Wenzel","year":"2007","unstructured":"Wenzel, S., Rohde, C., Wingerning, S., et al., 2007. Lack of endothelial nitric oxide synthase-derived nitric oxide formation favors hypertrophy in adult ventricular cardiomyocytes. Hypertension, 49(1):193\u2013200. http:\/\/dx.doi.org\/10.1161\/01.HYP.0000250468.02084.ce","journal-title":"Hypertension"},{"issue":"48","key":"199_CR75","doi-asserted-by":"publisher","first-page":"3404","DOI":"10.1093\/eurheartj\/ehv290","volume":"36","author":"S. Winnik","year":"2015","unstructured":"Winnik, S., Auwerx, J., Sinclair, D.A., 2015. Protective effects of sirtuins in cardiovascular diseases: from bench to bedside. Eur. Heart J., 36(48):3404\u20133412. http:\/\/dx.doi.org\/10.1093\/eurheartj\/ehv290","journal-title":"Eur. Heart J."},{"key":"199_CR76","doi-asserted-by":"crossref","unstructured":"Xia, W., Geng, K., 2016. A sirtuin activator and an antiinflammatory molecule-multifaceted roles of adjudin and its potential applications for aging-related diseases. Semin. Cell Dev. Biol., in press. http:\/\/dx.doi.org\/10.1016\/j.semcdb.2016.07.020","DOI":"10.1016\/j.semcdb.2016.07.020"},{"issue":"16","key":"199_CR77","doi-asserted-by":"publisher","first-page":"1810","DOI":"10.1161\/CIR.0b013e31829e8807","volume":"128","author":"C.W. Yancy","year":"2013","unstructured":"Yancy, C.W., Jessup, M., Bozkurt, B., et al., 2013. 2013 ACCF\/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines. Circulation, 128(16):1810\u20131852. http:\/\/dx.doi.org\/10.1161\/CIR.0b013e31829e8807","journal-title":"Circulation"},{"issue":"37","key":"199_CR78","doi-asserted-by":"publisher","first-page":"5310","DOI":"10.1038\/sj.onc.1210599","volume":"26","author":"X.J. Yang","year":"2007","unstructured":"Yang, X.J., Seto, E., 2007. HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention. Oncogene, 26(37):5310\u20135318. http:\/\/dx.doi.org\/10.1038\/sj.onc.1210599","journal-title":"Oncogene"},{"issue":"2","key":"199_CR79","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.yexcr.2016.07.006","volume":"347","author":"Z. Yue","year":"2016","unstructured":"Yue, Z., Ma, Y., You, J., et al., 2016. NMNAT3 is involved in the protective effect of SIRT3 in Ang II-induced cardiac hypertrophy. Exp. Cell Res., 347(2):261\u2013273. http:\/\/dx.doi.org\/10.1016\/j.yexcr.2016.07.006","journal-title":"Exp. Cell Res."},{"issue":"1","key":"199_CR80","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1373\/clinchem.2011.170431","volume":"58","author":"T. Zeller","year":"2012","unstructured":"Zeller, T., Blankenberg, S., Diemert, P., 2012. Genomewide association studies in cardiovascular disease\u2014an update 2011. Clin. Chem., 58(1):92\u2013103. http:\/\/dx.doi.org\/10.1373\/clinchem.2011.170431","journal-title":"Clin. Chem."},{"issue":"8","key":"199_CR81","doi-asserted-by":"publisher","first-page":"1847","DOI":"10.1111\/jcmm.12556","volume":"19","author":"H. Zeng","year":"2015","unstructured":"Zeng, H., Vaka, V.R., He, X., et al., 2015. High-fat diet induces cardiac remodelling and dysfunction: assessment of the role played by SIRT3 loss. J. Cell. Mol. Med., 19(8): 1847\u20131856. http:\/\/dx.doi.org\/10.1111\/jcmm.12556","journal-title":"J. Cell. Mol. Med."},{"issue":"6","key":"199_CR82","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1111\/j.1472-8206.2008.00620.x","volume":"22","author":"L. Zhang","year":"2008","unstructured":"Zhang, L., Zhang, Z., Guo, H., et al., 2008. Na+\/K+-ATPasemediated signal transduction and Na+\/K+-ATPase regulation. Fundam. Clin. Pharmacol., 22(6):615\u2013621. http:\/\/dx.doi.org\/10.1111\/j.1472-8206.2008.00620.x","journal-title":"Fundam. Clin. Pharmacol."},{"issue":"8","key":"199_CR83","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1631\/jzus.B1101010","volume":"12","author":"Y. Zhang","year":"2011","unstructured":"Zhang, Y., Huo, Y., 2011. Early reperfusion strategy for acute myocardial infarction: a need for clinical implementation. J. Zhejiang Univ.-Sci. B (Biomed. & Biotechnol.), 12(8): 629\u2013632. http:\/\/dx.doi.org\/10.1631\/jzus.B1101010","journal-title":"J. Zhejiang Univ.-Sci. B (Biomed. & Biotechnol.)"},{"issue":"2","key":"199_CR84","doi-asserted-by":"publisher","first-page":"200","DOI":"10.3181\/0707-RM-206","volume":"233","author":"X.J. Zou","year":"2008","unstructured":"Zou, X.J., Yang, L., Yao, S.L., 2008. Propofol depresses angiotensin II-induced cardiomyocyte hypertrophy in vitro. Exp. Biol. Med. (Maywood), 233(2):200\u2013208. http:\/\/dx.doi.org\/10.3181\/0707-RM-206","journal-title":"Exp. Biol. Med. (Maywood)"}],"container-title":["Journal of Zhejiang University-SCIENCE B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1631\/jzus.B1600253.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1631\/jzus.B1600253\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1631\/jzus.B1600253.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,15]],"date-time":"2019-09-15T11:47:33Z","timestamp":1568548053000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1631\/jzus.B1600253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":84,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["199"],"URL":"https:\/\/doi.org\/10.1631\/jzus.b1600253","relation":{},"ISSN":["1673-1581","1862-1783"],"issn-type":[{"value":"1673-1581","type":"print"},{"value":"1862-1783","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"http:\/\/orcid.org\/0000-0001-7586-5867","URL":"http:\/\/orcid.org\/0000-0001-7586-5867","order":0,"name":"name","label":"De-xing HU","group":{"name":"orcid","label":"ORCID"}},{"value":"http:\/\/orcid.org\/0000-0003-0409-8941","URL":"http:\/\/orcid.org\/0000-0003-0409-8941","order":0,"name":"name","label":"Jian-an WANG","group":{"name":"orcid","label":"ORCID"}},{"value":"doi:10.1631\/jzus.B1101010","URL":"http:\/\/www.zju.edu.cn\/jzus\/article.php?doi=10.1631\/jzus.B1101010","order":0,"name":"name","label":"Clinical effect of postconditioning...","group":{"name":"name","label":"Similar articles"}},{"value":"doi:10.1631\/jzus.B1101010","URL":"http:\/\/www.zju.edu.cn\/jzus\/article.php?doi=10.1631\/jzus.B1101010","order":1,"name":"name","label":"Early reperfusion strategy for...","group":{"name":"name","label":"Similar articles"}},{"value":"2016-05-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-07-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-18","order":2,"name":"crosschecked","label":"Crosschecked","group":{"name":"publication_history","label":"Publication History"}},{"value":"Review","order":0,"name":"content_type","group":{"name":"content_type","label":"Content Type"}},{"value":"\u00a9 Zhejiang University and Springer-Verlag Berlin Heidelberg 2016","order":0,"name":"copyright","group":{"name":"copyright","label":"Copyright"}}]}}