{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T01:44:45Z","timestamp":1790300685804,"version":"4.1.0"},"reference-count":37,"publisher":"Zhejiang University Press","issue":"10","license":[{"start":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T00:00:00Z","timestamp":1568073600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T00:00:00Z","timestamp":1568073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31472254"],"award-info":[{"award-number":["31472254"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Zhejiang Univ. Sci. B"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1631\/jzus.b1900071","type":"journal-article","created":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T05:22:17Z","timestamp":1568092937000},"page":"816-827","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":105,"title":["Catalpol ameliorates LPS-induced endometritis by inhibiting inflammation and TLR4\/NF-\u03baB signaling","\u6893\u9187\u901a\u8fc7\u6291\u5236\u708e\u75c7\u53cd\u5e94\u548c TLR4\/NF-\u03baB \u4fe1\u53f7\u901a\u8def\u6539\u5584\u8102\u591a\u7cd6\u8bf1\u5bfc\u7684\u5c0f\u9f20\u5b50\u5bab\u5185\u819c\u708e"],"prefix":"10.1631","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5847-1516","authenticated-orcid":false,"given":"Hua","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-min","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-ping","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aftab","family":"Shaukat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-fang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-ying","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-xia","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gan-zhen","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-mei","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"635","published-online":{"date-parts":[[2019,9,10]]},"reference":[{"key":"369_CR1","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1186\/1471-2180-10-172","volume":"10","author":"T Angrisano","year":"2010","unstructured":"Angrisano T, Pero R, Peluso S, et al., 2010. LPS-induced IL-8 activation in human intestinal epithelial cells is accompanied by specific histone H3 acetylation and methylation changes. BMC Microbiol, 10:172. \nhttps:\/\/doi.org\/10.1186\/1471-2180-10-172","journal-title":"BMC Microbiol"},{"issue":"3","key":"369_CR2","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1593\/neo.07976","volume":"10","author":"LA Begley","year":"2008","unstructured":"Begley LA, Kasina S, Mehra R, et al., 2008. CXCL5 promotes prostate cancer progression. Neoplasia, 10(3):244\u2013254. \nhttps:\/\/doi.org\/10.1593\/neo.07976","journal-title":"Neoplasia"},{"issue":"1","key":"369_CR3","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.theriogenology.2015.02.006","volume":"84","author":"P Brodzki","year":"2015","unstructured":"Brodzki P, Kostro K, Brodzki A, et al., 2015. Inflammatory cytokines and acute-phase proteins concentrations in the peripheral blood and uterus of cows that developed endometritis during early postpartum. Theriogenology, 84(1): 11\u201318. \nhttps:\/\/doi.org\/10.1016\/j.theriogenology.2015.02.006","journal-title":"Theriogenology"},{"issue":"6","key":"369_CR4","doi-asserted-by":"publisher","first-page":"2532","DOI":"10.1073\/pnas.90.6.2532","volume":"90","author":"K Brown","year":"1993","unstructured":"Brown K, Park S, Kanno T, et al., 1993. Mutual regulation of the transcriptional activator NF-KB and its inhibitor, I\u03baB\u03b1. Proc Natl Acad Sci USA, 90(6):2532\u20132536. \nhttps:\/\/doi.org\/10.1073\/pnas.90.6.2532","journal-title":"Proc Natl Acad Sci USA"},{"issue":"6","key":"369_CR5","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1631\/jzus.B1700277","volume":"19","author":"BY Chen","year":"2018","unstructured":"Chen BY, Jiang LX, Hao K, et al., 2018. Protection of plasma transfusion against lipopolysaccharide\/D-galactosamine-induced fulminant hepatic failure through inhibiting apoptosis of hepatic cells in mice. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 19(6):436\u2013444. \nhttps:\/\/doi.org\/10.1631\/jzus.B1700277","journal-title":"J Zhejiang Univ-Sci B (Biomed & Biotechnol)"},{"issue":"12","key":"369_CR6","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1631\/jzus.B1800095","volume":"19","author":"Z Chen","year":"2018","unstructured":"Chen Z, Deng S, Yuan DC, et al., 2018. Novel nano-microspheres containing chitosan, hyaluronic acid, and chondroitin sulfate deliver growth and differentiation factor-5 plasmid for osteoarthritis gene therapy. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 19(12): 910\u2013923. \nhttps:\/\/doi.org\/10.1631\/jzus.B1800095","journal-title":"J Zhejiang Univ-Sci B (Biomed & Biotechnol)"},{"issue":"4","key":"369_CR7","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1128\/CMR.14.4.821-835.2001","volume":"14","author":"SW Chensue","year":"2001","unstructured":"Chensue SW, 2001. Molecular machinations: chemokine signals in host-pathogen interactions. Clin Microbiol Rev, 14(4): 821\u2013835. \nhttps:\/\/doi.org\/10.1128\/CMR.14.4.821-835.2001","journal-title":"Clin Microbiol Rev"},{"issue":"4","key":"369_CR8","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.arteri.2014.02.007","volume":"26","author":"MA de Vries","year":"2014","unstructured":"de Vries MA, Klop B, Eskes SA, et al, 2014. The postprandial situation as a pro-inflammatory condition. Clin Investig Arterioscler, 26(4): 184\u2013192. \nhttps:\/\/doi.org\/10.1016\/j.arteri.2014.02.007","journal-title":"Clin Investig Arterioscler"},{"key":"369_CR9","doi-asserted-by":"publisher","first-page":"1496","DOI":"10.1016\/j.biopha.2018.08.149","volume":"107","author":"XN Feng","year":"2018","unstructured":"Feng XN, Zhang DF, Li XY, et al., 2018. CXCL5, the upregulated chemokine in patients with uterine cervix cancer, in vivo and in vitro contributes to oncogenic potential of Hela uterine cervix cancer cells. Biomed Pharmacother, 107:1496\u20131504. \nhttps:\/\/doi.org\/10.1016\/j.biopha.2018.08.149","journal-title":"Biomed Pharmacother"},{"key":"369_CR10","doi-asserted-by":"publisher","first-page":"982","DOI":"10.3389\/fphar.2018.00982","volume":"9","author":"S Guo","year":"2018","unstructured":"Guo S, Jiang KF, Wu HC, et al., 2018. Magnoflorine ameliorates lipopolysaccharide-induced acute lung injury via suppressing NF-\u03baB and MAPK activation. Front Pharmacol, 9:982. \nhttps:\/\/doi.org\/10.3389\/fphar.2018.00982","journal-title":"Front Pharmacol"},{"issue":"3","key":"369_CR11","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1292\/jvms.15-0415","volume":"78","author":"M Haas","year":"2016","unstructured":"Haas M, Kaup FJ, Neumann S, 2016. Canine pyometra: a model for the analysis of serum CXCL8 in inflammation. J Vet Med Sci, 78(3):375\u2013381. \nhttps:\/\/doi.org\/10.1292\/jvms.15-0415","journal-title":"J Vet Med Sci"},{"key":"369_CR12","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1186\/1477-7827-7-55","volume":"7","author":"S Herath","year":"2009","unstructured":"Herath S, Lilly ST, Santos NR, et al, 2009. Expression of genes associated with immunity in the endometrium of cattle with disparate postpartum uterine disease and fertility. Reprod Biol Endocrinol, 7:55. \nhttps:\/\/doi.org\/10.1186\/1477-7827-7-55","journal-title":"Reprod Biol Endocrinol"},{"issue":"4","key":"369_CR13","doi-asserted-by":"publisher","first-page":"463","DOI":"10.3109\/13880209.2012.740052","volume":"51","author":"CL Huang","year":"2013","unstructured":"Huang CL, Cui YL, Ji LL, et al., 2013. Catalpol decreases peroxynitrite formation and consequently exerts cardioprotective effects against ischemia\/reperfusion insult. Pharm Biol, 51(4):463\u2013473. \nhttps:\/\/doi.org\/10.3109\/13880209.2012.740052","journal-title":"Pharm Biol"},{"issue":"3","key":"369_CR14","doi-asserted-by":"publisher","first-page":"a000158","DOI":"10.1101\/cshperspect.a000158","volume":"2","author":"A Isra\u00ebl","year":"2010","unstructured":"Isra\u00ebl A, 2010. The IKK complex, a central regulator of NF-\u03baB activation. Cold Spring Harb Perspect Biol, 2(3):a000158. \nhttps:\/\/doi.org\/10.1101\/cshperspect.a000158","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"2","key":"369_CR15","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1089\/jir.2016.0058","volume":"37","author":"KF Jiang","year":"2017","unstructured":"Jiang KF, Chen XY, Zhao G, et al., 2017. IFN-x plays an anti-inflammatory role in Staphylococcus aureus-induced endometritis in mice through the suppression of NF-\u03baB pathway and MMP9 expression. J Interferon Cytokine Res, 37(2):81\u201389. \nhttps:\/\/doi.org\/10.1089\/jir.2016.0058","journal-title":"J Interferon Cytokine Res"},{"issue":"1","key":"369_CR16","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.theriogenology.2015.02.008","volume":"84","author":"I Karlsson","year":"2015","unstructured":"Karlsson I, Hagman R, Guo YZ, et al., 2015. Pathogenic Escherichia coli and lipopolysaccharide enhance the expression of IL-8, CXCL5, and CXCL10 in canine endometrial stromal cells. Theriogenology, 84(1): 34\u201342. \nhttps:\/\/doi.org\/10.1016\/j.theriogenology.2015.02.008","journal-title":"Theriogenology"},{"issue":"14","key":"369_CR17","doi-asserted-by":"publisher","first-page":"2244","DOI":"10.1016\/j.ejca.2011.11.032","volume":"48","author":"M Kawamura","year":"2012","unstructured":"Kawamura M, Toiyama Y, Tanaka K, et al., 2012. CXCL5, a promoter of cell proliferation, migration and invasion, is a novel serum prognostic marker in patients with colorectal cancer. Eur J Cancer, 48(14):2244\u20132251. \nhttps:\/\/doi.org\/10.1016\/j.ejca.2011.11.032","journal-title":"Eur J Cancer"},{"key":"369_CR18","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.theriogenology.2018.07.002","volume":"119","author":"T Koyama","year":"2018","unstructured":"Koyama T, Omori R, Koyama K, et al., 2018. Optimization of diagnostic methods and criteria of endometritis for various postpartum days to evaluate infertility in dairy cows. Theriogenology, 119:225\u2013232. \nhttps:\/\/doi.org\/10.1016\/j.theriogenology.2018.07.002","journal-title":"Theriogenology"},{"issue":"10","key":"369_CR19","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1038\/nri910","volume":"2","author":"QT Li","year":"2002","unstructured":"Li QT, Verma IM, 2002. NF-\u03baB regulation in the immune system. Nat Rev Immunol, 2(10): 725\u2013734. \nhttps:\/\/doi.org\/10.1038\/nri910","journal-title":"Nat Rev Immunol"},{"issue":"1","key":"369_CR20","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.brainres.2006.09.058","volume":"1123","author":"J Liu","year":"2006","unstructured":"Liu J, He QJ, Zou W, et al., 2006. Catalpol increases hippocampal neuroplasticity and up-regulates PKC and BDNF in the aged rats. Brain Res, 1123(1):68\u201379. \nhttps:\/\/doi.org\/10.1016\/j.brainres.2006.09.058","journal-title":"Brain Res"},{"issue":"6","key":"369_CR21","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1631\/jzus.B1600224","volume":"18","author":"A Lyu","year":"2017","unstructured":"Lyu A, Chen JJ, Wang HC, et al., 2017. Punicalagin protects bovine endometrial epithelial cells against lipopolysaccharide-induced inflammatory injury. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 18(6):481\u2013491. \nhttps:\/\/doi.org\/10.1631\/jzus.B1600224","journal-title":"J Zhejiang Univ-Sci B (Biomed & Biotechnol)"},{"key":"369_CR22","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.anireprosci.2018.08.039","volume":"197","author":"LF Machado Pfeifer","year":"2018","unstructured":"Machado Pfeifer LF, de Souza Andrade J, Moreira EM, et al., 2018. Uterine inflammation and fertility of beef cows subjected to timed AI at different days postpartum. Anim Reprod Sci, 197:26\u2013277. \nhttps:\/\/doi.org\/10.1016\/j.anireprosci.2018.08.039","journal-title":"Anim Reprod Sci"},{"issue":"10","key":"369_CR23","doi-asserted-by":"publisher","first-page":"7121","DOI":"10.4049\/jimmunol.179.10.7121","volume":"179","author":"C Nicholas","year":"2007","unstructured":"Nicholas C, Batra S, Vargo MA, et al., 2007. Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-KB through the suppression of p65 phosphorylation. J Immunol, 179(10):7121\u20137127. \nhttps:\/\/doi.org\/10.4049\/jimmunol.179.10.7121","journal-title":"J Immunol"},{"issue":"1","key":"369_CR24","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.tvjl.2007.12.031","volume":"176","author":"IM Sheldon","year":"2008","unstructured":"Sheldon IM, Williams EJ, Miller ANA, et al., 2008. Uterine diseases in cattle after parturition. Vet J, 176(1):115\u2013121. \nhttps:\/\/doi.org\/10.1016\/j.tvjl.2007.12.031","journal-title":"Vet J"},{"key":"369_CR25","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.plefa.2018.01.004","volume":"129","author":"Y Shen","year":"2018","unstructured":"Shen Y, Liu B, Mao W, et al, 2018. PGE2 downregulates LPS-induced inflammatory responses via the TLR4-NF-KB signaling pathway in bovine endometrial epithelial cells. Prostaglandins LeukotEssent Fatty Acids, 129:25\u201331. \nhttps:\/\/doi.org\/10.1016\/j.plefa.2018.01.004","journal-title":"Prostaglandins LeukotEssent Fatty Acids"},{"key":"369_CR26","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/s13567-018-0570-6","volume":"49","author":"R Sicsic","year":"2018","unstructured":"Sicsic R, Goshen T, Dutta R, et al., 2018. Microbial communities and inflammatory response in the endometrium differ between normal and metritic dairy cows at 5\u201310 days post-partum. Vet Res, 49:77. \nhttps:\/\/doi.org\/10.1186\/sl3567-018-0570-6","journal-title":"Vet Res"},{"key":"369_CR27","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.theriogenology.2018.09.013","volume":"122","author":"BM Socha","year":"2018","unstructured":"Socha BM, Lada P, et al., 2018. The influence of experimentally induced endometritis on the PPAR expression profile in the bovine endometrium. Theriogenology, 122: 74\u201383. \nhttps:\/\/doi.org\/10.1016\/j.theriogenology.2018.09.013","journal-title":"Theriogenology"},{"issue":"4","key":"369_CR28","doi-asserted-by":"publisher","first-page":"1453","DOI":"10.1210\/en.2013-1822","volume":"155","author":"ML Turner","year":"2014","unstructured":"Turner ML, Cronin JG, et al., 2014. Epithelial and stromal cells of bovine endometrium have roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides in vitro via Toll-like receptors TLR2, TLR1, and TLR6. Endocrinology, 155(4): 1453\u20131465. \nhttps:\/\/doi.org\/10.1210\/en.2013-1822","journal-title":"Endocrinology"},{"key":"369_CR29","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.theriogenology.2018.08.001","volume":"120","author":"SJ van Schyndel","year":"2018","unstructured":"van Schyndel SJ, Pascottini OB, et al., 2018. Comparison of cow-side diagnostic techniques for subclinical endometritis in dairy cows. Theriogenology, 120:117\u2013122. \nhttps:\/\/doi.org\/10.1016\/j.theriogenology.2018.08.001","journal-title":"Theriogenology"},{"key":"369_CR30","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.theriogenology.2017.02.005","volume":"94","author":"K Wagener","year":"2017","unstructured":"Wagener K, Gabler C, Drillich M, 2017. A review of the ongoing discussion about definition, diagnosis and pathomecha-nism of subclinical endometritis in dairy cows. Theriogenology, 94:21\u201330. \nhttps:\/\/doi.org\/10.1016\/j.theriogenology.2017.02.005","journal-title":"Theriogenology"},{"key":"369_CR31","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.gene.2018.07.074","volume":"677","author":"J Wang","year":"2018","unstructured":"Wang J, Yan XX, Nesengani LT, et al, 2018. LPS-induces IL-6 and IL-8 gene expression in bovine endometrial cells \u201cthrough DNA methylation\u201d. Gene, 677:266\u2013272. \nhttps:\/\/doi.org\/10.1016\/j.gene.2018.07.074","journal-title":"Gene"},{"issue":"3","key":"369_CR32","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1007\/sl0753-016-0348-9","volume":"39","author":"HC Wu","year":"2016","unstructured":"Wu HC, Zhao G, Jiang KF, et al., 2016. IFN-\u03c4 alleviates lipopolysaccharide-induced inflammation by suppressing NF-\u03baB and MAPKs pathway activation in mice. Inflammation, 39(3): 1141\u20131150. \nhttps:\/\/doi.org\/10.1007\/sl0753-016-0348-9","journal-title":"Inflammation"},{"issue":"1","key":"369_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.bbrc.2018.08.198","volume":"505","author":"C Yang","year":"2018","unstructured":"Yang C, Liu P, Wang S, et al., 2018. Shikonin exerts antiinflammatory effects in LPS-induced mastitis by inhibiting NF-KB signaling pathway. Biochem Biophys Res Commun, 505(1): 1\u20136. \nhttps:\/\/doi.org\/10.1016\/j.bbrc.2018.08.198","journal-title":"Biochem Biophys Res Commun"},{"issue":"8","key":"369_CR34","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1631\/jzus.B1800005","volume":"19","author":"GY Ye","year":"2018","unstructured":"Ye GY, Wang KY, Gui QD, et al., 2018. Ureaplasma urealyticum-derived lipid-associated membrane proteins introduce IL-6, IL-8, and TNF-\u03b1 cytokines into human amniotic epithelial cells via Toll-like receptor 2}. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 19(8):654\u2013661. \nhttps:\/\/doi.org\/10.1631\/jzus.B1800005","journal-title":"J Zhejiang Univ-Sci B (Biomed & Biotechnol)"},{"issue":"5","key":"369_CR35","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1016\/j.etp.2008.10.010","volume":"61","author":"AH Zhang","year":"2009","unstructured":"Zhang AH, Hao S, Bi J, et al., 2009. Effects of catalpol on mitochondrial function and working memory in mice after lipopolysaccharide-induced acute systemic inflammation. Exp Toxicol Pathol, 61(5):461\u2013469. \nhttps:\/\/doi.org\/10.1016\/j.etp.2008.10.010","journal-title":"Exp Toxicol Pathol"},{"issue":"3","key":"369_CR36","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.neulet.2010.02.054","volume":"473","author":"XL Zhang","year":"2010","unstructured":"Zhang XL, Liu WD, Niu XH, et al, 2010. Systemic administration of catalpol prevents D-galactose induced mitochondrial dysfunction in mice. Neurosci Lett, 473(3):224\u2013228. \nhttps:\/\/doi.org\/10.1016\/j.neulet.2010.02.054","journal-title":"Neurosci Lett"},{"issue":"2","key":"369_CR37","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1007\/s10753-018-0922-4","volume":"42","author":"G Zhao","year":"2019","unstructured":"Zhao G, Zhang T, Wu HC, et al, 2019. MicroRNA let-7c improves LPS-induced outcomes of endometritis by suppressing NF-\u03baB signaling. Inflammation, 42(2):650\u2013657. \nhttps:\/\/doi.org\/10.1007\/sl0753-018-0922-4","journal-title":"Inflammation"}],"updated-by":[{"DOI":"10.1631\/jzus.b19e0071","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2019,12,21]],"date-time":"2019-12-21T00:00:00Z","timestamp":1576886400000}}],"container-title":["Journal of Zhejiang University-SCIENCE B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1631\/jzus.B1900071.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1631\/jzus.B1900071\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1631\/jzus.B1900071.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T09:12:51Z","timestamp":1599729171000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1631\/jzus.B1900071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,10]]},"references-count":37,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["369"],"URL":"https:\/\/doi.org\/10.1631\/jzus.b1900071","relation":{"erratum":[{"id-type":"doi","id":"10.1631\/jzus.B19e0071","asserted-by":"object"}]},"ISSN":["1673-1581","1862-1783"],"issn-type":[{"value":"1673-1581","type":"print"},{"value":"1862-1783","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,10]]},"assertion":[{"value":"17 February 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 June 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 September 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 December 2019","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Erratum","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The original version of this article unfortunately contained a mistake. In p.823, Figs. 8c and 8d were incorrect, and the obvious pathological changes were mistakenly placed in the picture. The correct versions should be as follows:","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Hua ZHANG, Zhi-min WU, Ya-ping YANG, Aftab SHAUKAT, Jing YANG, Ying-fang GUO, Tao ZHANG, Xin-ying ZHU, Jin-xia QIU, Gan-zhen DENG, and Dong-mei SHI declare that they have no conflicts of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethics guidelines"}},{"value":"All institutional and national guidelines for the care and use of laboratory animals were followed. The animal experiments were carried out according to the guidelines of the Laboratory Animal Research Center of Hubei Province and approved by the Ethical Committee on Animal Research at Huazhong Agricultural University (HZAUMO-2015-12), Wuhan, China.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethics guidelines"}}]}}