{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:30:11Z","timestamp":1790649011295,"version":"4.1.0"},"reference-count":36,"publisher":"Zhejiang University Press","issue":"9","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"the Excellent Youth Fund of Zhejiang Province, China","award":["LR17C140002"],"award-info":[{"award-number":["LR17C140002"]}]}],"content-domain":{"domain":["springerlink.com","jzus.zju.edu.cn"],"crossmark-restriction":true},"short-container-title":["J. Zhejiang Univ. Sci. B"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1631\/jzus.b2100115","type":"journal-article","created":{"date-parts":[[2021,9,18]],"date-time":"2021-09-18T04:02:23Z","timestamp":1631937743000},"page":"767-773","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Effects of S-adenosylmethionine on production of secondary metabolites in Streptomyces diastatochromogenes 1628","S-\u817a\u82f7\u7532\u786b\u6c28\u9178\u5bf9\u6dc0\u7c89\u9176\u4ea7\u8272\u94fe\u9709\u83cc1628\u6b21\u7ea7\u4ee3\u8c22\u4ea7\u7269\u4ea7\u91cf\u7684\u5f71\u54cd"],"prefix":"10.1631","volume":"22","author":[{"given":"Yefeng","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1446-0708","authenticated-orcid":false,"given":"Zheng","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Bechthold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoping","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"635","published-online":{"date-parts":[[2021,9,18]]},"reference":[{"issue":"7","key":"546_CR1","doi-asserted-by":"publisher","first-page":"2227","DOI":"10.1039\/c0ob01054e","volume":"9","author":"U Battaglia","year":"2011","unstructured":"Battaglia U, Long JE, Searle MS, et al., 2011. 7-Deazapurine biosynthesis: NMR study of toyocamycin biosynthesis in Streptomyces rimosus using 2-13C-7-15N-adenine. Org Biomol Chem, 9(7):2227\u20132232. https:\/\/doi.org\/10.1039\/c0ob01054e","journal-title":"Org Biomol Chem"},{"issue":"15","key":"546_CR2","doi-asserted-by":"publisher","first-page":"2234","DOI":"10.1002\/cbic.201200402","volume":"13","author":"B Cao","year":"2012","unstructured":"Cao B, Yao F, Zheng XQ, et al., 2012. Genome mining of the biosynthetic gene cluster of the polyene macrolide antibiotic tetramycin and characterization of a P450 monooxygenase involved in the hydroxylation of the tetramycin B polyol segment. ChemBioChem, 13(15):2234\u20132242. https:\/\/doi.org\/10.1002\/cbic.201200402","journal-title":"ChemBioChem"},{"issue":"9","key":"546_CR3","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1007\/s10295-015-1660-3","volume":"42","author":"H Cui","year":"2015","unstructured":"Cui H, Ni XP, Shao W, et al., 2015. Functional manipulations of the tetramycin positive regulatory gene ttmRIV to enhance the production of tetramycin A and nystatin A1 in Streptomyces ahygroscopicus. J Ind Microbiol Biotechnol, 42(9):1273\u20131282. https:\/\/doi.org\/10.1007\/s10295-015-1660-3","journal-title":"J Ind Microbiol Biotechnol"},{"issue":"12","key":"546_CR4","doi-asserted-by":"publisher","first-page":"fnw109","DOI":"10.1093\/femsle\/fnw109","volume":"363","author":"H Cui","year":"2016","unstructured":"Cui H, Ni XP, Liu SJ, et al., 2016. Characterization of three positive regulators for tetramycin biosynthesis in Streptomyces ahygroscopicus. FEMS Microbiol Lett, 363(12): fnw109. https:\/\/doi.org\/10.1093\/femsle\/fnw109","journal-title":"FEMS Microbiol Lett"},{"issue":"5","key":"546_CR5","doi-asserted-by":"publisher","first-page":"e0232927","DOI":"10.1371\/journal.pone.0232927","volume":"15","author":"JX Fan","year":"2020","unstructured":"Fan JX, Song Y, Tang G, et al., 2020. Substantial improvement of tetraene macrolide production in Streptomyces diastatochromogenes by cumulative drug resistance mutations. PLoS ONE, 15(5):e0232927. https:\/\/doi.org\/10.1371\/journal.pone.0232927","journal-title":"PLoS ONE"},{"issue":"7","key":"546_CR6","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1007\/s12010-015-1958-7","volume":"178","author":"YY Gu","year":"2016","unstructured":"Gu YY, Wang XM, Chao Y, et al., 2016. Effects of chromosomal integration of the Vitreoscilla hemoglobin gene (vgb) and S-adenosylmethionine synthetase gene (metK) on \u03b5-poly-l-lysine synthesis in Streptomyces albulus NK660. Appl Biochem Biotechnol, 178(7):1445\u20131457. https:\/\/doi.org\/10.1007\/s12010-015-1958-7","journal-title":"Appl Biochem Biotechnol"},{"issue":"2","key":"546_CR7","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1111\/j.1574-6968.2004.tb09787.x","volume":"238","author":"JH Huh","year":"2004","unstructured":"Huh JH, Kim DJ, Zhao XQ, et al., 2004. Corrigendum to \u201cWidespread activation of antibiotic biosynthesis by S-adenosylmethionine in streptomycetes\u201d [FEMS Microbiol Lett. 238 (2004) 439\u2013447]. FEMS Microbiol Lett, 238(2):245. https:\/\/doi.org\/10.1016\/j.femsle.2004.08.009","journal-title":"FEMS Microbiol Lett"},{"issue":"2","key":"546_CR8","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1128\/JB.185.2.592-600.2003","volume":"185","author":"DJ Kim","year":"2003","unstructured":"Kim DJ, Huh JH, Yang YY, et al., 2003. Accumulation of S-adenosyl-l-methionine enhances production of actinorhodin but inhibits sporulation in Streptomyces lividans TK23. J Bacteriol, 185(2):592\u2013600. https:\/\/doi.org\/10.1128\/jb.185.2.592-600.2003","journal-title":"J Bacteriol"},{"key":"546_CR9","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.copbio.2020.11.006","volume":"69","author":"SS Li","year":"2021","unstructured":"Li SS, Li ZL, Pang S, et al., 2021. Coordinating precursor supply for pharmaceutical polyketide production in Streptomyces. Curr Opin Biotechnol, 69:26\u201334. https:\/\/doi.org\/10.1016\/j.copbio.2020.11.006","journal-title":"Curr Opin Biotechnol"},{"issue":"23","key":"546_CR10","doi-asserted-by":"publisher","first-page":"10191","DOI":"10.1007\/s00253-020-10955-8","volume":"104","author":"ZJ Liao","year":"2020","unstructured":"Liao ZJ, Song ZQ, Xu J, et al., 2020. Identification of a gene from Streptomyces rimosus M527 negatively affecting rimocidin biosynthesis and morphological differentiation. Appl Microbiol Biotechnol, 104(23):10191\u201310202. https:\/\/doi.org\/10.1007\/s00253-020-10955-8","journal-title":"Appl Microbiol Biotechnol"},{"issue":"1","key":"546_CR11","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1128\/MMBR.00054-12","volume":"77","author":"G Liu","year":"2013","unstructured":"Liu G, Chater KF, Chandra G, et al., 2013. Molecular regulation of antibiotic biosynthesis in Streptomyces. Microbiol Mol Biol Rev, 77(1):112\u2013143. https:\/\/doi.org\/10.1128\/MMBR.00054-12","journal-title":"Microbiol Mol Biol Rev"},{"issue":"4","key":"546_CR12","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1007\/s00253-019-10283-6","volume":"104","author":"Q Liu","year":"2020","unstructured":"Liu Q, Lin Q, Li XY, et al., 2020. Construction and application of a \u201csuperplasmid\u201d for enhanced production of antibiotics. Appl Microbiol Biotechnol, 104(4):1647\u20131660. https:\/\/doi.org\/10.1007\/s00253-019-10283-6","journal-title":"Appl Microbiol Biotechnol"},{"issue":"2","key":"546_CR13","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1007\/s00284-013-0461-z","volume":"68","author":"Z Ma","year":"2014","unstructured":"Ma Z, Liu JX, Bechthold A, et al., 2014a. Development of intergeneric conjugal gene transfer system in Streptomyces diastatochromogenes 1628 and its application for improvement of toyocamycin production. Curr Microbiol, 68(2):180\u2013185. https:\/\/doi.org\/10.1007\/s00284-013-0461-z","journal-title":"Curr Microbiol"},{"issue":"11","key":"546_CR14","doi-asserted-by":"publisher","first-page":"5051","DOI":"10.1007\/s00253-014-5573-2","volume":"98","author":"Z Ma","year":"2014","unstructured":"Ma Z, Tao LB, Bechthold A, et al., 2014b. Overexpression of ribosome recycling factor is responsible for improvement of nucleotide antibiotic-toyocamycin in Streptomyces diastatochromogenes 1628. Appl Microbiol Biotechnol, 98(11):5051\u20135058. https:\/\/doi.org\/10.1007\/s00253-014-5573-2","journal-title":"Appl Microbiol Biotechnol"},{"issue":"4","key":"546_CR15","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1007\/s10295-015-1732-4","volume":"43","author":"Z Ma","year":"2016","unstructured":"Ma Z, Luo S, Xu XH, et al., 2016. Characterization of representative rpoB gene mutations leading to a significant change in toyocamycin production of Streptomyces diastatochromogenes 1628. J Ind Microbiol Biotechnol, 43(4): 463\u2013471. https:\/\/doi.org\/10.1007\/s10295-015-1732-4","journal-title":"J Ind Microbiol Biotechnol"},{"key":"546_CR16","doi-asserted-by":"publisher","first-page":"2074","DOI":"10.3389\/fmicb.2020.02074","volume":"11","author":"Z Ma","year":"2020","unstructured":"Ma Z, Hu YF, Liao ZJ, et al., 2020. Cloning and overexpression of the toy cluster for titer improvement of toyocamycin in Streptomyces diastatochromogenes. Front Microbiol, 11: 2074. https:\/\/doi.org\/10.3389\/fmicb.2020.02074","journal-title":"Front Microbiol"},{"issue":"9","key":"546_CR17","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1007\/s10529-008-9735-0","volume":"30","author":"S Maharjan","year":"2008","unstructured":"Maharjan S, Oh TJ, Lee HC, et al., 2008. Heterologous expression of metK1-sp and afsR-sp in Streptomyces venezuelae for the production of pikromycin. Biotechnol Lett, 30(9):1621\u20131626. https:\/\/doi.org\/10.1007\/s10529-008-9735-0","journal-title":"Biotechnol Lett"},{"issue":"8","key":"546_CR18","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1016\/j.chembiol.2008.07.012","volume":"15","author":"RM McCarty","year":"2008","unstructured":"McCarty RM, Bandarian V, 2008. Deciphering deazapurine biosynthesis: pathway for pyrrolopyrimidine nucleosides toyocamycin and sangivamycin. Chem Biol, 15(8):790\u2013798. https:\/\/doi.org\/10.1016\/j.chembiol.2008.07.012","journal-title":"Chem Biol"},{"issue":"4","key":"546_CR19","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1093\/femsre\/fuw012","volume":"40","author":"GQ Niu","year":"2016","unstructured":"Niu GQ, Chater KF, Tian YQ, et al., 2016. Specialised metabolites regulating antibiotic biosynthesis in Streptomyces spp. FEMS Microbiol Rev, 40(4):554\u2013573. https:\/\/doi.org\/10.1093\/femsre\/fuw012","journal-title":"FEMS Microbiol Rev"},{"issue":"2","key":"546_CR20","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1111\/j.1365-2672.2010.04688.x","volume":"109","author":"TJ Oh","year":"2010","unstructured":"Oh TJ, Niraula NP, Liou K, et al., 2010. Identification of the duplicated genes for S-adenosyl-l-methionine synthetase (metK1-sp and metK2-sp) in Streptomyces peucetius var. caesius ATCC 27952. J Appl Microbiol, 109(2):398\u2013407. https:\/\/doi.org\/10.1111\/j.1365-2672.2010.04688.x","journal-title":"J Appl Microbiol"},{"issue":"2","key":"546_CR21","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1128\/JB.185.2.601-609.2003","volume":"185","author":"S Okamoto","year":"2003","unstructured":"Okamoto S, Lezhava A, Hosaka T, et al., 2003. Enhanced expression of S-adenosylmethionine synthetase causes overproduction of actinorhodin in Streptomyces coelicolor A3(2). J Bacteriol, 185(2):601\u2013609. https:\/\/doi.org\/10.1128\/jb.185.2.601-609.2003","journal-title":"J Bacteriol"},{"issue":"2","key":"546_CR22","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.femsle.2005.05.047","volume":"249","author":"HS Park","year":"2005","unstructured":"Park HS, Shin SK, Yang YY, et al., 2005. Accumulation of S-adenosylmethionine induced oligopeptide transporters including BldK to regulate differentiation events in Streptomyces coelicolor M145. FEMS Microbiol Lett, 249(2):199\u2013206. https:\/\/doi.org\/10.1016\/j.femsle.2005.05.047","journal-title":"FEMS Microbiol Lett"},{"issue":"7\u20138","key":"546_CR23","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1016\/j.micres.2013.09.017","volume":"169","author":"J Ren","year":"2014","unstructured":"Ren J, Cui YQ, Zhang F, et al., 2014. Enhancement of nystatin production by redirecting precursor fluxes after disruption of the tetramycin gene from Streptomyces ahygroscopicus. Microbiol Res, 169(7\u20138):602\u2013608. https:\/\/doi.org\/10.1016\/j.micres.2013.09.017","journal-title":"Microbiol Res"},{"issue":"6","key":"546_CR24","doi-asserted-by":"publisher","first-page":"2561","DOI":"10.1007\/s00253-020-10391-8","volume":"104","author":"Y Sheng","year":"2020","unstructured":"Sheng Y, Ou YX, Hu XJ, et al., 2020. Generation of tetramycin B derivative with improved pharmacological property based on pathway engineering. Appl Microbiol Biotechnol, 104(6):2561\u20132573. https:\/\/doi.org\/10.1007\/s00253-020-10391-8","journal-title":"Appl Microbiol Biotechnol"},{"key":"546_CR25","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.pestbp.2015.10.010","volume":"128","author":"X Shentu","year":"2016","unstructured":"Shentu X, Li DT, Xu JF, et al., 2016. Effects of fungicides on the yeast-like symbiotes and their host, Nilaparvata lugens St\u00e5l (Hemiptera: Delphacidae). Pestic Biochem Physiol, 128:16\u201321. https:\/\/doi.org\/10.1016\/j.pestbp.2015.10.010","journal-title":"Pestic Biochem Physiol"},{"issue":"11","key":"546_CR26","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1631\/jzus.B1900270","volume":"20","author":"ZQ Song","year":"2019","unstructured":"Song ZQ, Liao ZJ, Hu YF, et al., 2019. Development and optimization of an intergeneric conjugation system and analysis of promoter activity in Streptomyces rimosus M527. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 20(11):891\u2013900. https:\/\/doi.org\/10.1631\/jzus.B1900270","journal-title":"J Zhejiang Univ-Sci B (Biomed & Biotechnol)"},{"issue":"10","key":"546_CR27","doi-asserted-by":"publisher","first-page":"4445","DOI":"10.1007\/s00253-020-10565-4","volume":"104","author":"ZQ Song","year":"2020","unstructured":"Song ZQ, Ma Z, Bechthold A, et al., 2020. Effects of addition of elicitors on rimocidin biosynthesis in Streptomyces rimosus M527. Appl Microbiol Biotechnol, 104(10):4445\u20134455. https:\/\/doi.org\/10.1007\/s00253-020-10565-4","journal-title":"Appl Microbiol Biotechnol"},{"issue":"4\u20135","key":"546_CR28","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1007\/s10295-016-1883-y","volume":"44","author":"PP Tian","year":"2017","unstructured":"Tian PP, Cao P, Hu D, et al., 2017. Comparative metabolomics reveals the mechanism of avermectin production enhancement by S-adenosylmethionine. J Ind Microbiol Biotechnol, 44(4\u20135):595\u2013604. https:\/\/doi.org\/10.1007\/s10295-016-1883-y","journal-title":"J Ind Microbiol Biotechnol"},{"issue":"1","key":"546_CR29","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.enzmictec.2011.09.014","volume":"50","author":"T Wang","year":"2012","unstructured":"Wang T, Bai LQ, Zhu DQ, et al., 2012. Enhancing macrolide production in Streptomyces by coexpressing three heterologous genes. Enzyme Microb Technol, 50(1):5\u20139. https:\/\/doi.org\/10.1016\/j.enzmictec.2011.09.014","journal-title":"Enzyme Microb Technol"},{"issue":"2","key":"546_CR30","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1007\/s00253-007-1172-9","volume":"77","author":"Y Wang","year":"2007","unstructured":"Wang Y, Boghigian BA, Pfeifer BA, 2007. Improving heterologous polyketide production in Escherichia coli by overexpression of an S-adenosylmethionine synthetase gene. Appl Microbiol Biotechnol, 77(2):367\u2013373. https:\/\/doi.org\/10.1007\/s00253-007-1172-9","journal-title":"Appl Microbiol Biotechnol"},{"issue":"17","key":"546_CR31","doi-asserted-by":"publisher","first-page":"7071","DOI":"10.1007\/s00253-019-09959-w","volume":"103","author":"J Xu","year":"2019","unstructured":"Xu J, Song ZQ, Xu XH, et al., 2019. ToyA, a positive pathway-specific regulator for toyocamycin biosynthesis in Streptomyces diastatochromogenes 1628. Appl Microbiol Biotechnol, 103(17):7071\u20137084. https:\/\/doi.org\/10.1007\/s00253-019-09959-w","journal-title":"Appl Microbiol Biotechnol"},{"issue":"5","key":"546_CR32","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1007\/s10295-018-2029-1","volume":"45","author":"YR Xu","year":"2018","unstructured":"Xu YR, Tan GQ, Ke ML, et al., 2018. Enhanced lincomycin production by co-overexpression of metK1 and metK2 in Streptomyces lincolnensis. J Ind Microbiol Biotechnol, 45(5):345\u2013355. https:\/\/doi.org\/10.1007\/s10295-018-2029-1","journal-title":"J Ind Microbiol Biotechnol"},{"issue":"5","key":"546_CR33","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1007\/s11427-019-9497-5","volume":"62","author":"HZ Yin","year":"2019","unstructured":"Yin HZ, Wang WS, Fan KQ, et al., 2019. Regulatory perspective of antibiotic biosynthesis in Streptomyces. Sci China Life Sci, 62(5):698\u2013700. https:\/\/doi.org\/10.1007\/s11427-019-9497-5","journal-title":"Sci China Life Sci"},{"issue":"6","key":"546_CR34","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1007\/s00253-008-1394-5","volume":"78","author":"XC Zhang","year":"2008","unstructured":"Zhang XC, Fen MQ, Shi XL, et al., 2008. Overexpression of yeast S-adenosylmethionine synthetase metK in Streptomyces actuosus leads to increased production of nosiheptide. Appl Microbiol Biotechnol, 78(6):991\u2013995. https:\/\/doi.org\/10.1007\/s00253-008-1394-5","journal-title":"Appl Microbiol Biotechnol"},{"issue":"2","key":"546_CR35","doi-asserted-by":"publisher","first-page":"43","DOI":"10.3969\/j.issn.1005-7021.2010.02.009","volume":"30","author":"XH Zhao","year":"2010","unstructured":"Zhao XH, Zhong LJ, Zhang QH, et al., 2010. Effect of tetramycin on mycelial growth and spore germination of rice blast pathogen. J Microbiol, 30(2):43\u201345 (in Chinese). https:\/\/doi.org\/10.3969\/j.issn.1005-7021.2010.02.009","journal-title":"J Microbiol"},{"issue":"4","key":"546_CR36","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1007\/s00203-010-0548-x","volume":"192","author":"XQ Zhao","year":"2010","unstructured":"Zhao XQ, Gust B, Heide L, 2010. S-adenosylmethionine (SAM) and antibiotic biosynthesis: effect of external addition of SAM and of overexpression of SAM biosynthesis genes on novobiocin production in Streptomyces. Arch Microbiol, 192(4):289\u2013297. https:\/\/doi.org\/10.1007\/s00203-010-0548-x","journal-title":"Arch Microbiol"}],"container-title":["Journal of Zhejiang University-SCIENCE B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1631\/jzus.B2100115.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1631\/jzus.B2100115\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1631\/jzus.B2100115.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T08:32:30Z","timestamp":1637569950000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1631\/jzus.B2100115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":36,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["546"],"URL":"https:\/\/doi.org\/10.1631\/jzus.b2100115","relation":{},"ISSN":["1673-1581","1862-1783"],"issn-type":[{"value":"1673-1581","type":"print"},{"value":"1862-1783","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"https:\/\/orcid.org\/0000-0002-1446-0708","URL":"http","order":0,"name":"name","label":"Zheng MA","group":{"name":"orcid","label":"ORCID"}},{"value":"doi:10.1631\/jzus.B1900270","URL":"http:\/\/www.jzus.zju.edu.cn\/article.php?doi=10.1631\/jzus.B1900270","order":0,"name":"name","label":"Development and optimization of an intergeneric...","group":{"name":"name","label":"Similar articles"}},{"value":"2021-02-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-14","order":2,"name":"crosschecked","label":"Crosschecked","group":{"name":"publication_history","label":"Publication History"}},{"value":"Correspondence","order":0,"name":"content_type","group":{"name":"content_type","label":"Content Type"}},{"value":"\u00a9 Zhejiang University Press 2021","order":0,"name":"copyright","group":{"name":"copyright","label":"Copyright"}}]}}