{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:24:22Z","timestamp":1793305462652,"version":"4.5.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2009,8,1]],"date-time":"2009-08-01T00:00:00Z","timestamp":1249084800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective.<\/jats:title>\n                  <jats:p>To obtain prospective outcomes data on patients (pts) undergoing palliative operative or endoscopic procedures for malignant bowel obstruction due to recurrent ovarian cancer.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods.<\/jats:title>\n                  <jats:p>An institutional study was conducted from July 2002 to July 2003 to prospectively identify pts who underwent an operative or endoscopic procedure to palliate the symptoms of advanced cancer. This report focuses on pts with malignant bowel obstruction due to recurrent ovarian cancer. Procedures performed with an upper or lower gastrointestinal (GI) endoscope were considered \u201cendoscopic.\u201d All other cases were classified as \u201coperative.\u201d Following the procedure, the presence or absence of symptoms was determined and followed over time. All pts were followed until death.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results.<\/jats:title>\n                  <jats:p>Palliative interventions were performed on 74 gynecologic oncology pts during the study period, of which 26 (35%) were for malignant GI obstruction due to recurrent ovarian cancer. The site of obstruction was small bowel in 14 (54%) cases and large bowel in 12 (46%) cases. Palliative procedures were operative in 14 (54%) pts and endoscopic in the other 12 (46%). Overall, symptomatic improvement or resolution within 30 days was achieved in 23 (88%) of 26 patients, with 1 (4%) postprocedure mortality. At 60 days, 10 (71%) of 14 pts who underwent operative procedures and 6 (50%) of 12 pts who had endoscopic procedures had symptom control. Median survival from the time of the palliative procedure was 191 days (range, 33\u2013902) for those undergoing an operative procedure and 78 days (range, 18\u2013284) for those undergoing an endoscopic procedure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion.<\/jats:title>\n                  <jats:p>Patients with malignant bowel obstructions due to recurrent ovarian cancer have a high likelihood of experiencing relief of symptoms with palliative procedures. Although recurrence of symptoms is common, durable palliation and extended survival are possible, especially in those patients selected for operative intervention.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1634\/theoncologist.2009-0057","type":"journal-article","created":{"date-parts":[[2009,8,15]],"date-time":"2009-08-15T00:38:15Z","timestamp":1250296695000},"page":"835-839","source":"Crossref","is-referenced-by-count":52,"title":["A Prospective Outcomes Analysis of Palliative Procedures Performed for Malignant Intestinal Obstruction Due to Recurrent Ovarian Cancer"],"prefix":"10.1093","volume":"14","author":[{"given":"Dennis S.","family":"Chi","sequence":"first","affiliation":[{"name":"Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Pha\u00ebton","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital of University of Pennsylvania, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Miner","sequence":"additional","affiliation":[{"name":"Department of Surgery, Brown University, Providence, Rhode Island, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven V.","family":"Kardos","sequence":"additional","affiliation":[{"name":"George Washington University School of Medicine, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Diaz","sequence":"additional","affiliation":[{"name":"Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Mario M.","family":"Leitao","sequence":"additional","affiliation":[{"name":"Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ginger","family":"Gardner","sequence":"additional","affiliation":[{"name":"Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae","family":"Huh","sequence":"additional","affiliation":[{"name":"Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William P.","family":"Tew","sequence":"additional","affiliation":[{"name":"Solid Tumor Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason A.","family":"Konner","sequence":"additional","affiliation":[{"name":"Solid Tumor Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukio","family":"Sonoda","sequence":"additional","affiliation":[{"name":"Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadeem R.","family":"Abu-Rustum","sequence":"additional","affiliation":[{"name":"Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard R.","family":"Barakat","sequence":"additional","affiliation":[{"name":"Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David P.","family":"Jaques","sequence":"additional","affiliation":[{"name":"Washington University, St. Louis, Missouri, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,8,14]]},"reference":[{"key":"2021122207244346200_R1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S0002-9610(01)00646-8","article-title":"Discussion of death and dying in surgical textbooks","volume":"182","author":"Easson","year":"2001","journal-title":"Am J Surg"},{"key":"2021122207244346200_R2","volume-title":"Approaching Death-Improving Care at the End of Life","author":"Field","year":"1997"},{"key":"2021122207244346200_R3","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1245\/aso.2002.9.1.104","article-title":"Indications and use of palliative surgery: results of Society of Surgical Oncology survey","volume":"9","author":"McCahill","year":"2002","journal-title":"Ann Surg Oncol"},{"key":"2021122207244346200_R4","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1200\/JCO.1993.11.2.378","article-title":"Goals of palliative cancer therapy","volume":"11","author":"Porzsolt","year":"1993","journal-title":"J Clin Oncol"},{"key":"2021122207244346200_R5","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1097\/01.sla.0000141707.09312.dd","article-title":"A prospective, symptom related, outcomes analysis of 1022 palliative procedures for advanced cancer","volume":"240","author":"Miner","year":"2004","journal-title":"Ann Surg"},{"key":"2021122207244346200_R6","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/S1072-7515(02)01116-X","article-title":"Achieving R0 resection for locally advanced gastric cancer: is it worth the risk of multiorgan resection?","volume":"194","author":"Martin","year":"2002","journal-title":"J Am Coll Surg"},{"key":"2021122207244346200_R7","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1200\/JCO.1993.11.2.378","article-title":"Goals of palliative cancer therapy","volume":"11","author":"Prozsolft","year":"1993","journal-title":"J Clin Oncol"},{"key":"2021122207244346200_R8","volume-title":"Palliative Care","author":"World Health Organization","year":"2009"},{"key":"2021122207244346200_R9","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/S0002-9610(98)00323-7","article-title":"Decision making on surgical palliation based on patient outcome data","volume":"177","author":"Miner","year":"1999","journal-title":"Am J Surg"},{"issue":"4","key":"2021122207244346200_R10","first-page":"CD002764","article-title":"Surgery for the resolution of symptoms in malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer","author":"Feuer","year":"2000","journal-title":"Cochrane Database Syst Rev"},{"key":"2021122207244346200_R11","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/S0090-8258(03)00073-8","article-title":"Palliative surgery for bowel obstruction in recurrent ovarian cancer: an updated series","volume":"89","author":"Pothuri","year":"2003","journal-title":"Gynecol Oncol"},{"key":"2021122207244346200_R12","doi-asserted-by":"crossref","DOI":"10.1016\/j.ygyno.2004.09.058","article-title":"Percutaneous endoscopic gastrostomy tube placement in patients with malignant bowel obstruction due to ovarian carcinoma","volume-title":"Gynecol Oncol","author":"Pothuri","year":"2005"},{"key":"2021122207244346200_R13","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.ygyno.2007.11.035","article-title":"Colorectal stents for palliation of large bowel obstruction in recurrent gynecologic cancer: an updated series","volume":"108","author":"Caceres","year":"2008","journal-title":"Gynecol Oncol"}],"container-title":["The Oncologist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1634\/theoncologist.2009-0057","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1634\/theoncologist.2009-0057","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/oncolo\/article-pdf\/14\/8\/835\/41841286\/oncolo_14_8_835.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/oncolo\/article-pdf\/14\/8\/835\/41841286\/oncolo_14_8_835.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T08:48:23Z","timestamp":1640162903000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/oncolo\/article\/14\/8\/835\/6398017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8,1]]},"references-count":13,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2009,8,14]]},"published-print":{"date-parts":[[2009,8,1]]}},"URL":"https:\/\/doi.org\/10.1634\/theoncologist.2009-0057","relation":{},"ISSN":["1083-7159","1549-490X"],"issn-type":[{"value":"1083-7159","type":"print"},{"value":"1549-490X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2009,8,1]]},"published":{"date-parts":[[2009,8,1]]}}}