{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T11:21:25Z","timestamp":1792754485025,"version":"4.5.0"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2017,10,5]],"date-time":"2017-10-05T00:00:00Z","timestamp":1507161600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Randomized trials have established efficacy of supervised exercise training during chemotherapy for breast cancer for numerous health outcomes. The purpose of this study was to assess reach, effectiveness, maintenance, and implementation of an evidence-based exercise and healthy eating program offered within an adjuvant care setting.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Subjects, Materials, and Methods<\/jats:title>\n                  <jats:p>Women receiving adjuvant chemotherapy for breast cancer were given a prescription by their oncologist to participate in the Nutrition and Exercise during Adjuvant Treatment (NExT) program. The NExT program consisted of supervised, moderate-intensity, aerobic and resistance exercise three times a week during adjuvant therapy, followed by a step-down in supervised sessions per week for 20 additional weeks, plus one group-based healthy eating session. Usual moderate-to-vigorous physical activity (MVPA) and health-related quality of life (HRQoL) were assessed by questionnaire at baseline, program completion, and one year later, along with measures of satisfaction and safety.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Program reach encompassed referral of 53% of eligible patients, 78% uptake (n\u2009=\u200973 enrolled), and 78% retention for the 45.0\u2009\u00b1\u20098.3-week program. During the program, MVPA increased (116\u2009\u00b1\u200914 to 154\u2009\u00b1\u200914 minutes per week, p\u2009=\u2009.014) and HRQoL did not change. One year later, MVPA (171\u2009\u00b1\u200924 minutes per week, p\u2009=\u2009.014) and HRQoL (44\u2009\u00b1\u20091 to 49\u2009\u00b1\u20091, p\u2009&amp;lt;\u2009.001) were significantly higher than baseline. Exercise adherence was 60%\u2009\u00b1\u200926% to three sessions per week during treatment. No major adverse events occurred and injury prevalence did not change relative to baseline. Participants were highly satisfied.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This oncologist-referred exercise and healthy eating supportive-care program for breast cancer patients receiving chemotherapy was safe, successful in reaching oncologists and patients, and effective for improving MVPA and maintaining HRQoL.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Implications for Practice<\/jats:title>\n                  <jats:p>Despite evidence that exercise is both safe and efficacious at improving physical fitness, quality of life, and treatment side effects for individuals with cancer, lifestyle programming is not offered as standard of cancer care. This study describes an oncologist-referred, evidence-based exercise and healthy eating program offered in collaboration with a university as supportive care to women with breast cancer receiving chemotherapy. The program was well received by oncologists and patients, safe, and relatively inexpensive to operate. Importantly, there was a significant positive impact on physical activity levels and health-related quality of life lasting for 2 years after initiation of therapy.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1634\/theoncologist.2017-0141","type":"journal-article","created":{"date-parts":[[2017,10,6]],"date-time":"2017-10-06T01:00:19Z","timestamp":1507251619000},"page":"105-115","source":"Crossref","is-referenced-by-count":58,"title":["Effectiveness of Oncologist-Referred Exercise and Healthy Eating Programming as a Part of Supportive Adjuvant Care for Early Breast Cancer"],"prefix":"10.1093","volume":"23","author":[{"given":"Amy A.","family":"Kirkham","sequence":"first","affiliation":[{"name":"Rehabilitation Sciences, University of British Columbia, Vancouver, British Columbia, Canada, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheri L.","family":"Van Patten","sequence":"additional","affiliation":[{"name":"Oncology Nutrition, British Columbia Cancer Agency, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen A.","family":"Gelmon","sequence":"additional","affiliation":[{"name":"Medical Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald C.","family":"McKenzie","sequence":"additional","affiliation":[{"name":"School of Kinesiology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alis","family":"Bonsignore","sequence":"additional","affiliation":[{"name":"School of Kinesiology, University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelcey A.","family":"Bland","sequence":"additional","affiliation":[{"name":"Rehabilitation Sciences, University of British Columbia, Vancouver, British Columbia, Canada, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin L.","family":"Campbell","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Rehabilitation Sciences, University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,10,5]]},"reference":[{"key":"2021122509422906300_onco12283-bib-0001","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s11764-009-0110-5","article-title":"An update of controlled physical activity trials in cancer survivors: A systematic review and meta-analysis","volume":"4","author":"Speck","year":"2010","journal-title":"J Cancer Surviv"},{"key":"2021122509422906300_onco12283-bib-0002","doi-asserted-by":"crossref","first-page":"e70","DOI":"10.1136\/bmj.e70","article-title":"Physical activity for cancer survivors: Meta-analysis of randomised controlled trials","volume":"344","author":"Fong","year":"2012","journal-title":"BMJ"},{"key":"2021122509422906300_onco12283-bib-0003","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1093\/jnci\/djs207","article-title":"Physical activity, biomarkers, and disease outcomes in cancer survivors: A systematic review","volume":"104","author":"Ballard-Barbash","year":"2012","journal-title":"J Natl Cancer Inst"},{"key":"2021122509422906300_onco12283-bib-0004","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s10549-014-3162-9","article-title":"Safety and efficacy of progressive resistance training in breast cancer: A systematic review and meta-analysis","volume":"148","author":"Cheema","year":"2014","journal-title":"Breast Cancer Res Treat"},{"key":"2021122509422906300_onco12283-bib-0005","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/s12885-015-1069-4","article-title":"Effects of supervised exercise on cancer-related fatigue in breast cancer survivors: A systematic review and meta-analysis","volume":"15","author":"Meneses-Ech\u00e1vez","year":"2015","journal-title":"BMC Cancer"},{"key":"2021122509422906300_onco12283-bib-0006","doi-asserted-by":"crossref","first-page":"525","DOI":"10.2522\/ptj.20110115","article-title":"Factors that affect decisions about physical activity and exercise in survivors of breast cancer: A qualitative study","volume":"92","author":"Sander","year":"2012","journal-title":"Phys Ther"},{"key":"2021122509422906300_onco12283-bib-0007","first-page":"462","article-title":"Exploring social cognitive theory constructs for promoting exercise among breast cancer patients. 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