{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:23:05Z","timestamp":1771467785909,"version":"3.50.1"},"reference-count":3,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T00:00:00Z","timestamp":1566432000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Laser interstitial thermal therapy (LITT) is an emerging modality to treat benign and malignant brain lesions. LITT is a minimally invasive method to ablate tissue using laser-induced tissue heating and serves as both a diagnostic and therapeutic modality for progressive brain lesions. We completed a single-center retrospective analysis of all patients with progressive brain lesions treated with LITT since its introduction at our center in August of 2015. Twelve patients have been treated for a total of 13 procedures, of which 10 patients had brain metastases and 2 patients had primary malignant gliomas. Biopsies were obtained immediately prior to laser-induced tissue heating in 10 procedures (76.9%), of which seven biopsies showed treatment-related changes without viable tumor. After laser ablation, two of three patients previously on steroids were successfully weaned on first attempt. The results of this analysis indicate that LITT is a well-tolerated procedure enabling some patients to discontinue steroids that may be effective for diagnosing and treating radiation necrosis and tumor progression.<\/jats:p>","DOI":"10.1634\/theoncologist.2019-0213","type":"journal-article","created":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T20:39:16Z","timestamp":1566506356000},"page":"e1467-e1470","source":"Crossref","is-referenced-by-count":18,"title":["Outcomes in Patients Treated with Laser Interstitial Thermal Therapy for Primary Brain Cancer and Brain Metastases"],"prefix":"10.1093","volume":"24","author":[{"given":"Leigh Klaus","family":"Swartz","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine G.","family":"Holste","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle M.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aki","family":"Morikawa","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Heth","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,8,22]]},"reference":[{"key":"2021122508153755800_onco13074-bib-0001","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/jmri.1880040114","article-title":"Tissue temperature monitoring for thermal interventional therapy: Comparison of T1-weighted MR sequences","volume":"4","author":"Matsumoto","year":"1994","journal-title":"J Magn Reson Imaging"},{"key":"2021122508153755800_onco13074-bib-0002","doi-asserted-by":"crossref","first-page":"804","DOI":"10.3171\/2017.11.JNS171273","article-title":"Laser ablation after stereotactic radiosurgery: A multicenter prospective study in patients with metastatic brain tumors and radiation necrosis","volume":"130","author":"Ahluwalia","year":"2018","journal-title":"J Neurosurg"},{"key":"2021122508153755800_onco13074-bib-0003","doi-asserted-by":"crossref","first-page":"373","DOI":"10.3171\/2014.10.JNS141610","article-title":"Adverse radiation effect after stereotactic radiosurgery for brain metastases: Incidence, time course, and risk factors","volume":"123","author":"Sneed","year":"2015","journal-title":"J Neurosurg"}],"container-title":["The Oncologist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1634\/theoncologist.2019-0213","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1634\/theoncologist.2019-0213","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/oncolo\/article-pdf\/24\/12\/e1467\/41919598\/oncolo_24_12_e1467.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/oncolo\/article-pdf\/24\/12\/e1467\/41919598\/oncolo_24_12_e1467.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,25]],"date-time":"2021-12-25T08:16:03Z","timestamp":1640420163000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/oncolo\/article\/24\/12\/e1467\/6439540"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,22]]},"references-count":3,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,8,22]]},"published-print":{"date-parts":[[2019,12,1]]}},"URL":"https:\/\/doi.org\/10.1634\/theoncologist.2019-0213","relation":{},"ISSN":["1083-7159","1549-490X"],"issn-type":[{"value":"1083-7159","type":"print"},{"value":"1549-490X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,12,1]]},"published":{"date-parts":[[2019,8,22]]}}}