{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T08:13:52Z","timestamp":1777277632636,"version":"3.51.4"},"reference-count":39,"publisher":"American Association of Avian Pathologists (AAAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Avian Diseases"],"published-print":{"date-parts":[[2022,1,20]]},"DOI":"10.1637\/21-00108","type":"journal-article","created":{"date-parts":[[2022,2,18]],"date-time":"2022-02-18T09:50:15Z","timestamp":1645177815000},"source":"Crossref","is-referenced-by-count":8,"title":["Testicular Atrophy and Epididymitis-Orchitis Associated with Infectious Bronchitis Virus in Broiler Breeder Roosters"],"prefix":"10.1637","volume":"66","author":[{"given":"Rodrigo A.","family":"Gallardo","sequence":"first","affiliation":[{"name":"Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, 1089 Veterinary Medicine Drive, 4008 VM3B, Davis, CA 95616"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana P.","family":"da Silva","sequence":"additional","affiliation":[{"name":"Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, 1089 Veterinary Medicine Drive, 4008 VM3B, Davis, CA 95616"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin","family":"Gilbert","sequence":"additional","affiliation":[{"name":"Sanderson Farms, Inc., 127 Flynt Road, Laurel, MS 39443"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matilde","family":"Alfonso","sequence":"additional","affiliation":[{"name":"Ceva Animal Health, 8906 Rosehill Road, Lenexa, KS 66215"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Conley","sequence":"additional","affiliation":[{"name":"Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, 1089 Veterinary Medicine Drive, 4008 VM3B, Davis, CA 95616"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelli","family":"Jones","sequence":"additional","affiliation":[{"name":"Ceva Animal Health, 8906 Rosehill Road, Lenexa, KS 66215"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip A.","family":"Stayer","sequence":"additional","affiliation":[{"name":"Sanderson Farms, Inc., 127 Flynt Road, Laurel, MS 39443"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederic J.","family":"Hoerr","sequence":"additional","affiliation":[{"name":"Veterinary Diagnostic Pathology, LLC, 638 South Fort Valley Road, Fort Valley, VA 22652"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1212","reference":[{"key":"2","doi-asserted-by":"crossref","unstructured":"B Lucio  and J Fabricant  \"Avian Dis.\"  34, \"Tissue tropism of three cloacal isolates and Massachusetts strain of infectious bronchitis virus.\" 865 (1990)","DOI":"10.2307\/1591375"},{"key":"3","doi-asserted-by":"crossref","unstructured":"R Hauck, RA Gallardo, PR Woolcock, et al.  \"Avian Dis.\"  60, \"A coronavirus associated with runting stunting syndrome in broiler chickens.\" 528 (2016)","DOI":"10.1637\/11353-122215-Case"},{"key":"31","doi-asserted-by":"crossref","unstructured":"RA Gallardo, VL van Santen, H Toro,  \"Avian Dis.\"  54, \"Host intraspatial selection of infectious bronchitis virus populations.\" 807 (2010)","DOI":"10.1637\/9054-090809-Reg.1"},{"key":"32","doi-asserted-by":"crossref","unstructured":"MW Jackwood  and DH Lee  \"PLoS One.\"  12, \"Different evolutionary trajectories of vaccine-controlled and non-controlled avian infectious bronchitis viruses in commercial poultry.\" e0176709 (2017)","DOI":"10.1371\/journal.pone.0176709"},{"key":"20","doi-asserted-by":"crossref","unstructured":"RA Gallardo, FJ Hoerr, WD Berry, et al.  \"Avian Dis.\"  55, \"Infectious bronchitis virus in testicles and venereal transmission.\" 255 (2011)","DOI":"10.1637\/9592-102910-Reg.1"},{"key":"23","doi-asserted-by":"crossref","unstructured":"SA Callison, DA Hilt, TO Boynton, et al.  \"J Virol Methods.\"  138, \"Development and evaluation of a real-time Taqman rt-PCR assay for the detection of infectious bronchitis virus from infected chickens.\" 60 (2006)","DOI":"10.1016\/j.jviromet.2006.07.018"},{"key":"7","doi-asserted-by":"crossref","unstructured":"J Gelb, BS Ladman, CR Pope, et al.  \"Avian Dis.\"  57, \"Characterization of nephropathogenic infectious bronchitis virus DMV\/1639\/11 recovered from Delmarva broiler chickens in 2011.\" 65 (2013)","DOI":"10.1637\/10313-080212-Reg.1"},{"key":"9","doi-asserted-by":"crossref","unstructured":"RA Crinion  and MS Hofstad  \"Avian Dis.\"  16, \"Pathogenicity of four serotypes of avian infectious bronchitis virus for the oviduct of young chickens of various ages.\" 351 (1972)","DOI":"10.2307\/1588800"},{"key":"10","doi-asserted-by":"crossref","unstructured":"JJ de Wit, J Nieuwenhuisen-van Wilgen, A Hoogkamer, et al.  \"Avian Pathol.\"  40, \"Induction of cystic oviducts and protection against early challenge with infectious bronchitis virus serotype D388 (genotype QX) by maternally derived antibodies and by early vaccination.\" 463 (2011)","DOI":"10.1080\/03079457.2011.599060"},{"key":"6","doi-asserted-by":"crossref","unstructured":"Z Benyeda, T Mat\u00f3, T S\u00fcveges, et al.  \"Avian Pathol.\"  38, \"Comparison of the pathogenicity of QX-like, M41 and 793\/B infectious bronchitis strains from different pathological conditions.\" 449 (2009)","DOI":"10.1080\/03079450903349196"},{"key":"14","doi-asserted-by":"crossref","unstructured":"RH Duff, JW Macdonald, DA McMartin, et al.  \"Vet Rec.\"  88, \"Infection of day-old chicks with infectious bronchitis (IB) virus and subsequent anatomical abnormalities.\" 315 (1971)","DOI":"10.1136\/vr.88.12.315"},{"key":"11","doi-asserted-by":"crossref","unstructured":"E Parent, A Gagnon-Francoeur, B Lanthier, et al.  \"Avian Dis.\"  64, \"Diagnostic accuracy of ultrasonography to detect false layers in a commercial laying flock infected by an infectious bronchitis virus Delmarva genotype causing cystic oviducts.\" 149 (2020)","DOI":"10.1637\/0005-2086-64.2.149"},{"key":"12","doi-asserted-by":"crossref","unstructured":"AP da Silva, C Giroux, HS Sellers, et al.  \"Avian Dis.\"  65, \"Characterization of an infectious bronchitis virus isolated from commercial layers suffering from false layer syndrome.\" 373 (2021)","DOI":"10.1637\/aviandiseases-D-21-00037"},{"key":"13","doi-asserted-by":"crossref","unstructured":"RC Jones  and FT Jordan  \"Vet Rec.\"  87, \"The exposure of day-old chicks to infectious bronchitis and the subsequent development of the oviduct.\" 504 (1970)","DOI":"10.1136\/vr.87.17.504"},{"key":"1","doi-asserted-by":"crossref","unstructured":"MW Jackwood  and S de Wit  \"Diseases of poultry.\"  \"Infectious bronchitis.\" 167 (2020)","DOI":"10.1002\/9781119371199.ch4"},{"key":"34","doi-asserted-by":"crossref","unstructured":"NA Pereira, AC Alessi, HJ Montassier, et al.  \"Braz J Microbiol.\"  50, \"Gonadal pathogenicity of an infectious bronchitis virus strain from the Massachusetts genotype.\" 313 (2019)","DOI":"10.1007\/s42770-018-0007-4"},{"key":"17","doi-asserted-by":"crossref","unstructured":"DA Boltz, CR Zimmerman, M Nakai, et al.  \"Avian Dis.\"  50, \"Epididymal stone formation and decreased sperm production in roosters vaccinated with a killed strain of avian infectious bronchitis virus.\" 594 (2006)","DOI":"10.1637\/7654-052506R.1"},{"key":"30","doi-asserted-by":"crossref","unstructured":"JJ. De Wit,  \"Avian Pathol.\"  29, \"Detection of infectious bronchitis virus.\" 71 (2000)","DOI":"10.1080\/03079450094108"},{"key":"35","doi-asserted-by":"crossref","unstructured":"JKA. Cook,  \"J Comp Pathol.\"  81, \"Recovery of infectious bronchitis virus from eggs and chicks produced by experimentally inoculated hens.\" 203 (1971)","DOI":"10.1016\/0021-9975(71)90093-4"},{"key":"4","doi-asserted-by":"crossref","unstructured":"AP da Silva, R Hauck, SRC Nociti, et al.  \"Viruses.\"  13, \"Molecular biology and pathological process of an infectious bronchitis virus with enteric tropism in commercial broilers.\" 1477 (2021)","DOI":"10.3390\/v13081477"},{"key":"5","doi-asserted-by":"crossref","unstructured":"G Meulemans  and TP van den Berg  \"World Poultry Sci J.\"  54, \"Nephropathogenic avian infectious bronchitis viruses.\" 145 (1998)","DOI":"10.1079\/WPS19980011"},{"key":"8","doi-asserted-by":"crossref","unstructured":"DI Broadfoot, BS Pomeroy, WM Smith,  \"Poultry Sci.\"  35, \"Effects of infectious bronchitis in baby chicks.\" 757 (1956)","DOI":"10.3382\/ps.0350757"},{"key":"15","doi-asserted-by":"crossref","unstructured":"SJ Janssen, JD Kirby, RA Hess, et al.  \"Poultry Sci.\"  79, \"Identification of epididymal stones in diverse rooster populations.\" 568 (2000)","DOI":"10.1093\/ps\/79.4.568"},{"key":"16","doi-asserted-by":"crossref","unstructured":"DA Boltz, M Nakai, JM Bahr,  \"Avian Dis.\"  48, \"Avian infectious bronchitis virus: a possible cause of reduced fertility in the rooster.\" 909 (2004)","DOI":"10.1637\/7192-040808R1"},{"key":"18","doi-asserted-by":"crossref","unstructured":"J Sarabia Fragoso, M Pizarro D\u00edaz, J Abad Moreno, et al.  \"Reprod Domest Anim.\"  48, \"Relationships between fertility and some parameters in male broiler breeders (body and testicular weight, histology and immunohistochemistry of testes, spermatogenesis and hormonal levels).\" 345 (2013)","DOI":"10.1111\/j.1439-0531.2012.02161.x"},{"key":"19","doi-asserted-by":"crossref","unstructured":"LY Villarreal, PE Brand\u00e3o, JL Chac\u00f3n, et al.  \"Avian Dis.\"  51, \"Orchitis in roosters with reduced fertility associated with avian infectious bronchitis virus and avian metapneumovirus infections.\" 900 (2007)","DOI":"10.1637\/7815-121306-REGR4.1"},{"key":"21","unstructured":"\"Live production reports, 2009\u20132021.\""},{"key":"22","doi-asserted-by":"crossref","unstructured":"M Fran\u00e7a, PR Woolcock, M Yu, et al.  \"Avian Dis.\"  55, \"Nephritis associated with infectious bronchitis virus Cal99 variant in game chickens.\" 422 (2011)","DOI":"10.1637\/9417-060510-Reg.1"},{"key":"24","unstructured":"J Gelb  and MW Jackwood  \"A laboratory manual for the isolation, identification and characterization of avian pathogens.\"  \"Infectious bronchitis.\" (2016)"},{"key":"25","doi-asserted-by":"crossref","unstructured":"HJ Roh, DA Hilt, MW Jackwood,  \"Avian Dis.\"  58, \"Detection of infectious bronchitis virus with the use of real-time quantitative reverse transcriptase-PCR and correlation with virus detection in embryonated eggs.\" 398 (2014)","DOI":"10.1637\/10764-010914-Reg.1"},{"key":"26","doi-asserted-by":"crossref","unstructured":"J Mo, M Angelichio, L Gow, et al.  \"J Virol Methods.\"  276, \"Validation of specific quantitative real-time RT-PCR assay panel for infectious bronchitis using synthetic DNA standards and clinical specimens.\" 113773 (2020)","DOI":"10.1016\/j.jviromet.2019.113773"},{"key":"27","unstructured":"GH Stabenfeldt, JP Hughes, PC Kennedy, et al.  \"J Rep Fer S.\"  \"Clinical findings, pathological changes and endocrinological secretory patterns in mares with ovarian tumours.\" 277 (1979)"},{"key":"28","unstructured":"M-EB Morin, S Ch\u00e9nier, N Bergeron,  \"Bulletin Zoosanitaire.\"  \"La bronchite infectieuse aviaire au qu\u00e9bec. Qu\u00e9bec, Canada.\" (2018)"},{"key":"29","unstructured":"K Grogan, M Fran\u00e7a, B Jordan, et al.  \"Proceedings of the 63rd American Association of Avian Pathologists Annual Meeting. 2020 Jul 30\u2013Aug 6; Virtual.\"  \"Case report: clinical and histopathological findings in the first reported case of false layer syndrome in Georgia.\""},{"key":"33","doi-asserted-by":"crossref","unstructured":"UH Jackson, DA Boltz, M Nakai, et al.  \"J Poult Sci.\"  43, \"Prepubertal exposure to the live attenuated avian infectious bronchitis virus induces epididymal stones in the rooster after puberty.\" 280 (2006)","DOI":"10.2141\/jpsa.43.280"},{"key":"36","doi-asserted-by":"crossref","unstructured":"RA Niznik, RF Wideman, BS Cowen, et al.  \"Poultry Sci.\"  64, \"Induction of urolithiasis in single comb white leghorn pullets: effect on glomerular number 1.\" 1430 (1985)","DOI":"10.3382\/ps.0641430"},{"key":"37","doi-asserted-by":"crossref","unstructured":"BS Cowen, RF Wideman, MO Braune, et al.  \"Avian Dis.\"  31, \"An infectious bronchitis virus isolated from chickens experiencing a urolithiasis outbreak. I. In vitro characterization studies.\" 878 (1987)","DOI":"10.2307\/1591045"},{"key":"38","doi-asserted-by":"crossref","unstructured":"MM. Lowry,  \"Poultry Sci.\"  37, \"Compensatory testicular adjustments following the injection of small quantities of androgen into unilaterally castrated white leghorn cockerels.\" 1129 (1958)","DOI":"10.3382\/ps.0371129"},{"key":"39","doi-asserted-by":"crossref","unstructured":"Z Benyeda, L Szeredi, T Mat\u00f3, et al.  \"J Comp Pathol.\"  143, \"Comparative histopathology and immunohistochemistry of QX-like, Massachusetts and 793\/B serotypes of infectious bronchitis virus infection in chickens.\" 276 (2010)","DOI":"10.1016\/j.jcpa.2010.04.007"}],"container-title":["Avian Diseases"],"original-title":[],"deposited":{"date-parts":[[2022,4,7]],"date-time":"2022-04-07T19:54:19Z","timestamp":1649361259000},"score":1,"resource":{"primary":{"URL":"https:\/\/bioone.org\/journals\/avian-diseases\/volume-66\/issue-1\/21-00108\/Testicular-Atrophy-and-Epididymitis-Orchitis-Associated-with-Infectious-Bronchitis-Virus\/10.1637\/21-00108.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,20]]},"references-count":39,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,3,1]]}},"URL":"https:\/\/doi.org\/10.1637\/21-00108","relation":{},"ISSN":["0005-2086"],"issn-type":[{"value":"0005-2086","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1,20]]}}}