{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T05:32:03Z","timestamp":1793424723988,"version":"4.5.0"},"reference-count":56,"publisher":"American Association of Avian Pathologists (AAAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Avian Diseases"],"published-print":{"date-parts":[[2023,12,18]]},"abstract":"<jats:p>Evoluci\u00f3n y perfil gen\u00f3mico de aislados de Salmonella enterica serovar Gallinarum biovar Pullorum de Brasil. Salmonella enterica subespecie enterica serovar Gallinarum biovar Pullorum (S. Pullorum) es una bacteria pat\u00f3gena que causa la enfermedad de Pullorum (EP). La EP es una enfermedad sist\u00e9mica aguda que afecta a los pollos j\u00f3venes causando diarrea blanca y alta mortalidad. Aunque se han llevado a cabo muchos programas sanitarios para erradicar S. Pullorum, se han informado brotes de EP en diferentes tipos de aves (ponedoras, pollos de engorde, reproductoras) en todo el mundo. Este estudio tuvo como objetivo evaluar la evoluci\u00f3n y las caracter\u00edsticas gen\u00e9ticas de S. Pullorum aislado de EP en Brasil. El an\u00e1lisis filogen\u00e9tico de los genomas de S. Pullorum secuenciados en este estudio y las bases de datos gen\u00f3micas disponibles demostraron que todos los aislamientos de Brasil son del tipo de secuencia 92 (ST92) y se agrupan en dos linajes (III y IV). ColpVC, IncFIC (FII) e IncFII(S) fueron replicones de pl\u00e1smidos frecuentemente encontrados en los linajes brasile\u00f1os. Dos genes de resistencia (aac(6\u2032)-Iaa, que confiere resistencia a aminogluc\u00f3sidos, desinfectantes y antis\u00e9pticos (mdf(A)), y tetraciclina (mdf(A)) fueron detectados con frecuencia. En conjunto, estos resultados son importantes para comprender la circulaci\u00f3n de S. Pullorum y, en consecuencia, desarrollar estrategias para reducir las p\u00e9rdidas por EP.<\/jats:p>","DOI":"10.1637\/aviandiseases-d-23-00017","type":"journal-article","created":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T09:44:00Z","timestamp":1714038240000},"page":"2-9","source":"Crossref","is-referenced-by-count":0,"title":["Evolution and genomic profile of Salmonella enterica serovar Gallinarum biovar Pullorum isolates from Brazil"],"prefix":"10.1637","volume":"68","author":[{"given":"Di\u00e9ssy","family":"Kipper","sequence":"first","affiliation":[{"name":"Simbios Biotecnologia, Cachoeirinha, 94940-030, Rio Grande do Sul, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"De Carli","sequence":"additional","affiliation":[{"name":"Molecular Diagnostics Laboratory, Lutheran University of Brazil (ULBRA), Canoas, 92425-350, Rio Grande do Sul, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"de Souza Zanetti","sequence":"additional","affiliation":[{"name":"Molecular Diagnostics Laboratory, Lutheran University of Brazil (ULBRA), Canoas, 92425-350, Rio Grande do Sul, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Karoline","family":"Mascitti","sequence":"additional","affiliation":[{"name":"Institute of Biotechnology, University of Caxias do Sul (UCS), Caxias do Sul, 95070-560, Rio Grande do Sul, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 Salvador","family":"Kazantzi Fonseca","sequence":"additional","affiliation":[{"name":"Simbios Biotecnologia, Cachoeirinha, 94940-030, Rio Grande do Sul, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilo","family":"Ikuta","sequence":"additional","affiliation":[{"name":"Simbios Biotecnologia, Cachoeirinha, 94940-030, Rio Grande do Sul, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vagner Ricardo","family":"Lunge","sequence":"additional","affiliation":[{"name":"Simbios Biotecnologia, Cachoeirinha, 94940-030, Rio Grande do Sul, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1212","reference":[{"key":"31","doi-asserted-by":"crossref","unstructured":"E Zankari, H Hasman, S Cosentino, et al.  \"J Antimicrob Chemother.\"  67, \"Identification of acquired antimicrobial resistance genes.\" 2640 (2012)","DOI":"10.1093\/jac\/dks261"},{"key":"27","doi-asserted-by":"crossref","unstructured":"AJ Drummond, MA Suchard, D Xie, et al.  \"Mol Biol Evol.\"  29, \"Bayesian phylogenetics with BEAUti and the BEAST 1.7.\" 1969 (2012)","DOI":"10.1093\/molbev\/mss075"},{"key":"29","doi-asserted-by":"publisher","unstructured":"A Rambaut, AJ Drummond, D Xie, et al.  \"Syst Biol.\"  67, \"Posterior summarization in bayesian phylogenetics using Tracer 1.7.\" 901 (2018)","DOI":"10.1093\/sysbio\/syy032"},{"key":"16","doi-asserted-by":"publisher","unstructured":"AM Bolger, M 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\"Genes (Basel.\"  11, \"Genotypic and phenotypic characterization of incompatibility group FIB positive Salmonella enterica serovar Typhimurium isolates from food animal sources.\" 1307 (2020)","DOI":"10.3390\/genes11111307"},{"key":"46","doi-asserted-by":"crossref","unstructured":"Y Li, X Kang, A Ed-Dra, et al.  \"Microbiol Spectr.\"  10, \"Genome-based assessment of antimicrobial resistance and virulence potential of isolates of non-Pullorum\/Gallinarum Salmonella serovars recovered from dead poultry in China.\" e0096522 (2022)","DOI":"10.1128\/spectrum.00965-22"},{"key":"47","doi-asserted-by":"crossref","unstructured":"EA McMillan, SK Gupta, LE Williams, et al.  \"Front Microbiol.\"  10, \"Antimicrobial resistance genes, cassettes, and plasmids present in Salmonella enterica associated with United States food animals.\" 832 (2019)","DOI":"10.3389\/fmicb.2019.00832"},{"key":"48","doi-asserted-by":"crossref","unstructured":"GL Rodrigues, P Panzenhagen, RG Ferrari, et al.  \"Front Microbiol.\"  11, \"Frequency of antimicrobial resistance genes in Salmonella from Brazil by in silico whole-genome sequencing analysis: an overview of the last four decades.\" 1864 (2020)","DOI":"10.3389\/fmicb.2020.01864"},{"key":"49","doi-asserted-by":"crossref","unstructured":"AK Mascitti, D Kipper, RO Dos Reis, et al.  \"Braz J Microbiol.\"  52, \"Retrospective whole-genome comparison of Salmonella enterica serovar Enteritidis from foodborne outbreaks in southern Brazil.\" 1523 (2021)","DOI":"10.1007\/s42770-021-00508-0"},{"key":"50","doi-asserted-by":"crossref","unstructured":"BP Alcock, AR Raphenya, TTY Lau, et al.  \"Nucleic Acids Res.\"  48, \"CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database.\" D517 (2020)","DOI":"10.1093\/nar\/gkz935"},{"key":"52","doi-asserted-by":"crossref","unstructured":"J Yin, Z Cheng, Z Xu, et al.  \"Microb Pathog.\"  171, \"Contribution of prgH gene for Salmonella Pullorum to virulence and the 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(2022)","DOI":"10.1016\/j.psj.2021.101655"},{"key":"56","doi-asserted-by":"crossref","unstructured":"X Kang, X Zhou, Y Tang, et al.  \"Int J Mol Sci.\"  23, \"Characterization of two-component system CitB family in Salmonella Pullorum.\" 10201 (2022)","DOI":"10.3390\/ijms231710201"},{"key":"23","doi-asserted-by":"publisher","unstructured":"J Trifinopoulos, LT Nguyen, A von Haeseler, et al.  \"Nucleic Acids Res.\"  44, \"W-IQ-TREE: a fast online phylogenetic tool for maximum likelihood analysis.\" W232 (2016)","DOI":"10.1093\/nar\/gkw256"}],"container-title":["Avian 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