{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:50:55Z","timestamp":1791237055973,"version":"4.1.0"},"reference-count":33,"publisher":"American Association of Avian Pathologists (AAAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Avian Diseases"],"published-print":{"date-parts":[[2026,5,26]]},"abstract":"<jats:p>Reporte de caso- Hepatitis necr\u00f3tica asociada a la coinfecci\u00f3n por Phasianus chaphamaparvovirus 1 y coccidiosis en faisanes j\u00f3venes (Phasianus colchicus) en Bosnia y Herzegovina. Phasianus chaphamaparvovirus 1 es un pat\u00f3geno de reciente reconocimiento asociado a una elevada mortalidad en faisanes j\u00f3venes, lo que conlleva p\u00e9rdidas significativas para los criadores de esta especie. En el presente trabajo, se describe un brote de hepatitis necrotizante con alta mortalidad en una parvada de faisanes j\u00f3venes en Bosnia y Herzegovina, asociado a una coinfecci\u00f3n por Phasianus chaphamaparvovirus 1 y coccidiosis. El examen microsc\u00f3pico revel\u00f3 una hepatitis necrotizante grave, caracterizada por la presencia de cuerpos de inclusi\u00f3n intranucleares en los hepatocitos afectados. Asimismo, se observaron \u00e1reas multifocales de necrosis en la mucosa intestinal, con presencia de numerosos estadios de desarrollo (merontes) de coccidios. La detecci\u00f3n de Phasianus chaphamaparvovirus 1 se realiz\u00f3 mediante qPCR a partir de muestras hep\u00e1ticas de las aves enfermas. Este informe constituye el primer reporte sobre la presencia de este nuevo virus en parvadas de faisanes en la regi\u00f3n de los Balcanes, sugiriendo que dicho virus se encuentra ampliamente distribuido por toda Europa. Adem\u00e1s, respalda la inclusi\u00f3n de Chaphamaparvovirus como diagn\u00f3stico diferencial ante brotes de mortalidad en faisanes, tanto en instalaciones de cr\u00eda como en poblaciones silvestres.<\/jats:p>","DOI":"10.1637\/aviandiseases-d-25-00111","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T10:39:08Z","timestamp":1782988748000},"page":"235-239","source":"Crossref","is-referenced-by-count":0,"title":["Necrotic Hepatitis Associated with Phasianus Chaphamaparvovirus 1 and Coccidiosis Coinfection in Pheasant Chicks (Phasianus colchicus) in Bosnia and Herzegovina"],"prefix":"10.1637","volume":"70","author":[{"given":"Ajla Hod\u017e\u00ed\u0107","family":"Bor\u00ed\u0107","sequence":"first","affiliation":[{"name":"Veterinary Faculty, University of Sarajevo, Zmaja od Bosne 90, 71000 Sarajevo, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jovana","family":"Dervov\u00ed\u0107","sequence":"additional","affiliation":[{"name":"Veterinary Faculty, University of Sarajevo, Zmaja od Bosne 90, 71000 Sarajevo, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alma","family":"\u0160eho-Al\u00ed\u0107","sequence":"additional","affiliation":[{"name":"Veterinary Faculty, University of Sarajevo, Zmaja od Bosne 90, 71000 Sarajevo, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adis","family":"Soft\u00ed\u0107","sequence":"additional","affiliation":[{"name":"Veterinary Faculty, University of Sarajevo, Zmaja od Bosne 90, 71000 Sarajevo, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0160ejla Golet\u00ed\u0107","family":"Imamov\u00ed\u0107","sequence":"additional","affiliation":[{"name":"Veterinary Faculty, University of Sarajevo, Zmaja od Bosne 90, 71000 Sarajevo, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teufik","family":"Golet\u00ed\u0107","sequence":"additional","affiliation":[{"name":"Veterinary Faculty, University of Sarajevo, Zmaja od Bosne 90, 71000 Sarajevo, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amer","family":"Al\u00ed\u0107","sequence":"additional","affiliation":[{"name":"Veterinary Faculty, University of Sarajevo, Zmaja od Bosne 90, 71000 Sarajevo, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1212","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"MR Ashrafzadeh, R Khosravi, C Fernandes, et al.  \"Sci Rep.\"  11, \"Assessing the origin, genetic structure and demographic history of the common pheasant (Phasianus colchicus) in the introduced European range.\" 21721 (2021)","DOI":"10.1038\/s41598-021-00567-1"},{"key":"2","doi-asserted-by":"publisher","unstructured":"F Santilli  and M Bagliacca  \"Wildl Biol.\"  14, \"Factors influencing pheasant Phasianus colchicus harvesting in Tuscany, Italy.\" 281 (2008)","DOI":"10.2981\/0909-6396(2008)14[281:FIPPCH]2.0.CO;2"},{"key":"3","doi-asserted-by":"publisher","unstructured":"T. Pennycott,  \"Practice.\"  23, \"Disease control in adult pheasants.\" 132 (2001)","DOI":"10.1136\/inpract.23.3.132"},{"key":"4","doi-asserted-by":"publisher","unstructured":"IA Dwight, PS Coates, ST Stoute, et al.  \"Transbound Emerg Dis.\"  69, \"Health surveillance of a potential bridge host: pathogen exposure risks posed to avian populations augmented with captive-bred pheasants.\" 1095 (2022)","DOI":"10.1111\/tbed.14068"},{"key":"5","doi-asserted-by":"publisher","unstructured":"EW Aldous  and DJ Alexander  \"Vet J.\"  175, \"Newcastle disease in pheasants (Phasianus colchicus): a review.\" 181 (2008)","DOI":"10.1016\/j.tvjl.2006.12.012"},{"key":"8","doi-asserted-by":"publisher","unstructured":"SS Kapgate, K Kumanan, K Vijayarani, et al.  \"Avian Pathol.\"  47, \"Avian parvovirus: classification, phylogeny, pathogenesis and diagnosis.\" 536 (2018)","DOI":"10.1080\/03079457.2018.1517938"},{"key":"11","doi-asserted-by":"publisher","unstructured":"E Fahsbender, E Altan, MA Seguin, et al.  \"Viruses.\"  11, \"Chapparvovirus DNA found in 4% of dogs with diarrhea.\" 398 (2019)","DOI":"10.3390\/v11050398"},{"key":"12","doi-asserted-by":"crossref","unstructured":"G Lanave, G Diakoudi, F Pellegrini, et al.  \"Microbiol Spectr.\"  11, \"Novel parvovirus in an outbreak of fatal enteritis in European hedgehogs (Erinaceus europaeus), Italy, 2022.\" e02494 (2023)","DOI":"10.1128\/spectrum.02494-23"},{"key":"13","doi-asserted-by":"publisher","unstructured":"Y Li, E Gordon, A Idle, et al.  \"Viruses.\"  12, \"Virome of a feline outbreak of diarrhea and vomiting includes bocaviruses and a novel chapparvovirus.\" 506","DOI":"10.3390\/v12050506"},{"key":"14","doi-asserted-by":"publisher","unstructured":"RM Palinski, N Mitra, BM Hause,  \"Virus Genes.\"  52, \"Discovery of a novel Parvovirinae virus, porcine parvovirus 7, by metagenomic sequencing of porcine rectal swabs.\" 564 (2016)","DOI":"10.1007\/s11262-016-1322-1"},{"key":"15","doi-asserted-by":"publisher","unstructured":"S Yang, Z Liu, Y Wang, et al.  \"Virol J.\"  13, \"A novel rodent Chapparvovirus in feces of wild rats.\" 133 (2016)","DOI":"10.1186\/s12985-016-0589-0"},{"key":"16","doi-asserted-by":"publisher","unstructured":"M Canuti, JTP Verhoeven, H J Munro, et al.  \"Viruses.\"  13, \"Investigating the diversity and host range of novel parvoviruses from North American ducks using epidemiology, phylogenetics, genome structure, and codon usage analysis.\" 193","DOI":"10.3390\/v13020193"},{"key":"17","doi-asserted-by":"publisher","unstructured":"S Fran\u00e7ois, SC Hill, CM Perrins, et al.  \"Microbiol Resour Announc.\"  13, \"Characterization of the genomic sequence of a circo-like virus and of three chaphamaparvoviruses detected in mute swan (Cygnus olor).\" e0118623 (2024)","DOI":"10.1128\/mra.01186-23"},{"key":"19","doi-asserted-by":"publisher","unstructured":"X Liu, H Wang, X Liu, et al.  \"Virology.\"  539, \"Genomic and transcriptional analyses of novel parvoviruses identified from dead peafowl.\" 80","DOI":"10.1016\/j.virol.2019.10.013"},{"key":"20","doi-asserted-by":"publisher","unstructured":"G Reuter, \u00c1 Boros, E Delwart, et al.  \"Arch Virol.\"  159, \"Novel circular single-stranded DNA virus from turkey faeces.\" 2161 (2014)","DOI":"10.1007\/s00705-014-2025-3"},{"key":"21","doi-asserted-by":"publisher","unstructured":"S. Sarker,  \"Pathogens.\"  10, \"Molecular and phylogenetic characterisation of a highly divergent novel parvovirus (Psittaciform Chaphamaparvovirus 2) in Australian neophema parrots.\" 1559","DOI":"10.3390\/pathogens10121559"},{"key":"22","doi-asserted-by":"publisher","unstructured":"S Sarker, A Athukorala, DN Phalen,  \"Microbiol Resour Announc.\"  11, \"Characterization of a near-complete genome sequence of a chaphamaparvovirus from an Australian boobook owl (Ninox boobook).\" e0024922 (2022)","DOI":"10.1128\/mra.00249-22"},{"key":"23","doi-asserted-by":"publisher","unstructured":"Q Zhao, R Zhao, Y Sun, et al.  \"Viruses.\"  15, \"Identification of multiple novel viruses in fecal samples of black-necked cranes using viral metagenomic methods.\" 2068","DOI":"10.3390\/v15102068"},{"key":"24","doi-asserted-by":"publisher","unstructured":"Y Zhang, S Talukder, MSA Bhuiyan, et al.  \"Virology.\"  595, \"Opportunistic sampling of yellow canary (Crithagra flaviventris) has revealed a high genetic diversity of detected parvoviral sequences.\" 110081 (2024)","DOI":"10.1016\/j.virol.2024.110081"},{"key":"27","doi-asserted-by":"publisher","unstructured":"M Balfour, C Garcia-Rueda, M Matos,  \"Vet Rec Case Rep.\"  13, \"First confirmed outbreak of Phasianus chaphamaparvovirus 1 infection in pheasants in the UK.\" e70120 (2025)","DOI":"10.1002\/vrc2.70120"},{"key":"28","doi-asserted-by":"publisher","unstructured":"E Saenz, N Streitenberger, AG Armien, et al.  \"Avian Dis.\"  69, \"First report of emerging chaphamaparvovirus causing necrotizing hepatitis in pheasants (Phasianus colchicus) in the United States.\" 426","DOI":"10.1637\/aviandiseases-D-25-00045"},{"key":"29","doi-asserted-by":"crossref","unstructured":"RE Porter  and TY Morishita  \"Gamebird medicine and management.\"  \"Gamebird digestive diseases.\" 220 (2023)","DOI":"10.1002\/9781119712244"},{"key":"30","doi-asserted-by":"publisher","unstructured":"MN Rosen, F Brian, BF Hunter, et al.  \"Avian Dis.\"  9, \"Preliminary study of an infectious hepatitis in pheasants.\" 382 (1965)","DOI":"10.2307\/1588368"},{"key":"#cr-split#-31.1","unstructured":"G Grilli, V Ferrazzi, G Cislaghii, et al. \"Proc. 57th Western Poultry Disease Conference. 2008 Apr 9-12"},{"key":"#cr-split#-31.2","unstructured":"Puerto Vallarta, Jalisco, Mexico.\" \"Parvovirus-like hepatitis in grey partridge (Perdix perdix): preliminary observations.\" 207 (2008)"},{"key":"32","doi-asserted-by":"publisher","unstructured":"L Liebing, I Volker, N Curland, et al.  \"PLoS ONE.\"  15, \"Health status of free-ranging ring-necked pheasant chicks (Phasianus colchicus) in North-Western Germany.\" e0234044","DOI":"10.1371\/journal.pone.0234044"},{"key":"26","doi-asserted-by":"crossref","unstructured":"M Matos, I Bilic, J Tvarogov\u00e1, et al.  \"Sci Rep.\"  12, \"A novel genotype of avian hepatitis E virus identified in chickens and common pheasants (Phasianus colchicus), extending its host range.\" 21743 (2022)","DOI":"10.1038\/s41598-022-26103-3"},{"key":"7","doi-asserted-by":"crossref","unstructured":"M Matos, I Bilic, N Viloux, et al.  \"Transbound Emerg Dis.\"  69, \"A novel Chaphamaparvovirus is the etiological agent of hepatitis outbreaks in pheasants (Phasianus colchicus) characterized by high mortality.\" e2093 (2022)","DOI":"10.1111\/tbed.14545"},{"key":"25","doi-asserted-by":"crossref","unstructured":"D Gelmetti, M Fabbi, G Sironi, et al.  \"J Vet Diagn Invest.\"  8, \"Identification of parvovirus-like particles associated with three outbreaks of mortality in young pheasants (Phasianus colchicus).\" 108 (1996)","DOI":"10.1177\/104063879600800118"},{"key":"9","doi-asserted-by":"crossref","unstructured":"MA Soliman, AM Erfan, M Samy, et al.  \"Animals.\"  10, \"Detection of novel goose parvovirus disease associated with short beak and dwarfism syndrome in commercial ducks.\" 2020 (1833)","DOI":"10.3390\/ani10101833"},{"key":"18","doi-asserted-by":"crossref","unstructured":"DA Lima, SP Cibulski, C Tochetto, et al.  \"Virus Res.\"  261, \"The intestinal virome of malabsorption syndrome-affected and unaffected broilers through shotgun metagenomics.\" 9 (2019)","DOI":"10.1016\/j.virusres.2018.12.005"},{"key":"6","unstructured":"S Rautenschlein, HM Mahsoub, SD Fitzgerald, et al.  \"Diseases of poultry.\"  \"Hemorrhagic enteritis and related infections.\" 339 (2020)"},{"key":"10","doi-asserted-by":"crossref","unstructured":"JJ P\u00e9nzes, M S\u00f6derlund-Venermo, M Canuti, et al.  \"Arch Virol.\"  165, \"Reorganizing the family Parvoviridae: a revised taxonomy independent of the canonical approach based on host association.\" 2133 (2020)","DOI":"10.1007\/s00705-020-04632-4"}],"container-title":["Avian 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