{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T09:18:25Z","timestamp":1785921505307,"version":"3.56.0"},"reference-count":33,"publisher":"American Association of Zoo Veterinarians","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Zoo and Wildlife Medicine"],"published-print":{"date-parts":[[2023,7,7]]},"DOI":"10.1638\/2021-0133","type":"journal-article","created":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T12:40:56Z","timestamp":1688733656000},"source":"Crossref","is-referenced-by-count":5,"title":["PRELIMINARY EVALUATION OF SYMMETRIC DIMETHYLARGININE AS A BIOMARKER OF RENAL INSUFFICIENCY IN WILD AND REHABILITATED FLORIDA MANATEES (TRICHECHUS MANATUS LATIROSTRIS)"],"prefix":"10.1638","volume":"54","author":[{"given":"Lauren N.","family":"Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert K.","family":"Bonde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa R.","family":"Nau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ray L.","family":"Ball","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1213","reference":[{"key":"8","doi-asserted-by":"crossref","unstructured":"KR Friedrichs, K Harr, KP Freeman, et al.  \"Vet Clin Pathol.\"  41, \"ASVCP reference interval guidelines: determination of de novo reference intervals in veterinary species and other related topics.\" 441 (2012)","DOI":"10.1111\/vcp.12006"},{"key":"19","doi-asserted-by":"crossref","unstructured":"CA Manire, CJ Walsh, HL Rhinehart, et al.  \"Zoo Biol.\"  22, \"Alterations in blood and urine parameters in two Florida manatees (Trichechus manatus latirostris) from simulated conditions of release following rehabilitation.\" 103 (2003)","DOI":"10.1002\/zoo.10074"},{"key":"9","doi-asserted-by":"crossref","unstructured":"JA Hall, M Yerramilli, E Obare, et al.  \"J Vet Intern Med.\"  30, \"Serum concentrations of symmetric dimethylarginine and creatinine in dogs with naturally occurring chronic kidney disease.\" 794 (2016)","DOI":"10.1111\/jvim.13942"},{"key":"10","doi-asserted-by":"crossref","unstructured":"JA Hall, M Yerramilli, E Obare, et al.  \"J Vet Intern Med.\"  28, \"Comparison of serum concentrations of symmetric dimethylarginine and creatinine as kidney function biomarkers in cats with chronic kidney disease.\" 1676 (2014)","DOI":"10.1111\/jvim.12445"},{"key":"16","doi-asserted-by":"crossref","unstructured":"B Lamglait  and M Vandenbunder-Beltrame  \"J Zoo Wildl Med.\"  48, \"Evaluation of symmetric dimethylarginine as an early biomarker of chronic kidney disease in captive cheetahs (Acinonyx jubatus).\" 874 (2017)","DOI":"10.1638\/2016-0224.1"},{"key":"21","doi-asserted-by":"crossref","unstructured":"MB Nabity, GE Lees, MM Boggess, et al.  \"J Vet Intern Med.\"  29, \"Symmetric dimethylarginine assay validation, stability, and evaluation as a marker for the early detection of chronic kidney disease in dogs.\" 1036 (2015)","DOI":"10.1111\/jvim.12835"},{"key":"4","unstructured":"RK Bonde, A Garrett, M Berlanger, et al.  \"J Mar Anim Ecol.\"  5, \"Biomedical health assessments of the Florida manatee in Crystal River\u2014Providing opportunities for training during the capture, handling, and processing of this unique aquatic mammal.\" 17 (2012)"},{"key":"1","doi-asserted-by":"crossref","unstructured":"BJ Andrews, AC Cushing, RE Murphy, et al.  \"J Am Vet Assoc.\"  260, \"Blood concentration of symmetric dimethylarginine correlates with kidney damage as assessed with a proposed histologic grading system for chronic kidney disease in tigers (Panthera tigris).\" 1 (2022)","DOI":"10.2460\/javma.21.04.0216"},{"key":"2","doi-asserted-by":"crossref","unstructured":"R Baral, KP Freeman, B Flatland,  \"J Feline Med Surg.\"  23, \"Comparison of serum and plasma SDMA measured with point-of-care and reference laboratory analysers: implications for interpretation of SDMA in cats.\" 906 (2021)","DOI":"10.1177\/1098612X20983260"},{"key":"3","doi-asserted-by":"crossref","unstructured":"A Barratclough, RL Ball, R Francis Floyd, et al.  \"J Zoo Wildl Med.\"  48, \"Proposal and application of a novel disseminated intravascular coagulation scoring system in the Florida manatee (Trichcehus manatus latirostris).\" 152 (2017)","DOI":"10.1638\/2016-0050.1"},{"key":"5","doi-asserted-by":"crossref","unstructured":"L Cabrias-Contreras, R S\u00e1nchez-Okrucky, D Caicedo-Herrara, et al.  \"J Am Vet Med Assoc.\"  258, \"Baseline urinalysis results in 32 healthy Antillean manatees (Trichechus manatus manatus).\" 416 (2021)","DOI":"10.2460\/javma.258.4.416"},{"key":"6","doi-asserted-by":"crossref","unstructured":"AC Cushing, R Murphy, D Szlosek, et al.  \"J Zoo Wildl Med.\"  53, \"Method comparison for measurement of symmetric dimethylarginine in tigers (Panthera tigris).\" 200 (2022)","DOI":"10.1638\/2021-0067"},{"key":"7","unstructured":"MR Davis  and MT Walsh  \"CRC handbook of marine mammal medicine.\"  \"Sirenian Medicine.\" 970 (2018)"},{"key":"11","doi-asserted-by":"crossref","unstructured":"JA Hall, M Yerramilli, E Obare, et al.  \"J Vet Intern Med.\"  29, \"Relationship between lean body mass and renal biomarkers in healthy dogs.\" 808 (2015)","DOI":"10.1111\/jvim.12607"},{"key":"12","doi-asserted-by":"crossref","unstructured":"K Harr, R Rember, P Ginn, et al.  \"J Wildl Dis.\"  47, \"Serum amyloid A (SAA) as a biomarker of chronic infection due to boat strike trauma in a free-ranging Florida manatee (Trichechus manatus latirostris) with incidental polycystic kidneys.\" 1026 (2011)","DOI":"10.7589\/0090-3558-47.4.1026"},{"key":"13","doi-asserted-by":"crossref","unstructured":"JW Harvey, KE Harr, D Murphy, et al.  \"J Wildl Dis.\"  38, \"Clinical biochemistry in healthy manatees (Trichechus manatus latirostris).\" 269 (2007)","DOI":"10.1638\/1042-7260(2007)038[0269:CBIHMT]2.0.CO;2"},{"key":"14","doi-asserted-by":"crossref","unstructured":"M Keller, J Moliner, G Vasquez, et al.  \"J Wildl Dis.\"  44, \"Nephrolithiasis and pyelonephritis in two West Indian Manatees (Trichechus manatus spp.).\" 707 (2008)","DOI":"10.7589\/0090-3558-44.3.707"},{"key":"15","doi-asserted-by":"crossref","unstructured":"K Kryzanowska, F Mittermayer, N Shnawa, et al.  \"Diabet Med.\"  24, \"Asymmetrical dimethylarginine is related to renal function, chronic inflammation and macroangiopathy in patients with type 2 diabetes and albuminuria.\" 81 (2007)","DOI":"10.1111\/j.1464-5491.2007.02018.x"},{"key":"17","doi-asserted-by":"crossref","unstructured":"R Liffman, R Johnstone, B Tennent-Brown, et al.  \"Vet Clin Pathol.\"  47, \"Establishment of reference intervals for serum symmetric dimethylarginine in adult nonracing Greyhounds.\" 458 (2018)","DOI":"10.1111\/vcp.12638"},{"key":"18","doi-asserted-by":"crossref","unstructured":"JD Lightsey, SA Rommel, AM Costidis, et al.  \"J Zoo Wildl Med.\"  37, \"Methods used during gross necropsy to determine watercraft-related mortality in the Florida manatee (Trichechus manatus latirostris).\" 262 (2006)","DOI":"10.1638\/04-095.1"},{"key":"20","doi-asserted-by":"crossref","unstructured":"SM Mota, J Brand\u00ebo, A Guthrie,  \"J Zoo Wildl Med.\"  52, \"Comparison of blood symmetric dimethylarginine and creatinine as endogenous markers of kidney function in captive tigers (Panthera tigris).\" 628 (2021)","DOI":"10.1638\/2020-0032"},{"key":"22","doi-asserted-by":"crossref","unstructured":"S Paltrinieri, M Giraldi, A Prolo, et al.  \"J Feline Med Surg.\"  20, \"Serum symmetric dimethylarginine and creatinine in Birman cats compared with cats of other breeds.\" 905 (2018)","DOI":"10.1177\/1098612X17734066"},{"key":"23","doi-asserted-by":"crossref","unstructured":"J Raulic, B Lamglait, C Vergneau-Grosset,  \"J Zoo Wildl Med.\"  52, \"Use of symmetric dimethylarginine to detect renal lesions in fish: a preliminary study in brook trout (Salvelinus fontinalis).\" 1024 (2021)","DOI":"10.1638\/2020-0218"},{"key":"24","unstructured":"V Rentko, M Nabity, M Yerramilli,  \"J Vet Intern Med.\"  27, \"Determination of serum symmetric dimethylarginine reference limit in clinically healthy dogs [ACVIM Abstract P-7].\" 750 (2013)"},{"key":"25","doi-asserted-by":"crossref","unstructured":"HC Schott II, LR Gallant, M Coyne, et al.  \"J Vet Intern Med.\"  35, \"Symmetric dimethylarginine and creatinine concentrations in serum of healthy draft horses.\" 1147 (2021)","DOI":"10.1111\/jvim.16042"},{"key":"26","doi-asserted-by":"crossref","unstructured":"N Siwinska, A Zak, M Slowikowska, et al.  \"BMC Vet Res.\"  16, \"Serum symmetric dimethylarginine concentration in healthy horses and horses with acute kidney injury.\" 396 (2020)","DOI":"10.1186\/s12917-020-02621-y"},{"key":"27","doi-asserted-by":"crossref","unstructured":"N Speight, M Gates, T Scriven, et al.  \"Aust Vet J.\"  98, \"Symmetric dimethylarginine values in koalas (Phascolarctos cinereus) based on oxalate nephrosis status.\" 247 (2020)","DOI":"10.1111\/avj.12935"},{"key":"28","unstructured":"\"Florida manatee recovery plan.\"  (2001)"},{"key":"29","doi-asserted-by":"crossref","unstructured":"S Venn-Watson, CR Smith, C Dold, et al.  \"Mar Mamm Sci.\"  24, \"Use of a serum-based glomerular filtration rate prediction equation to assess renal function by age, sex, fasting, and health status in bottlenose dolphins (Tursiops truncatus).\" 71 (2008)","DOI":"10.1111\/j.1748-7692.2007.00162.x"},{"key":"30","doi-asserted-by":"crossref","unstructured":"L Waugh, S Lyon, GA Cole,  \"J Zoo Wildl Med.\"  49, \"Retrospective analysis and validation of serum symmetric dimethylarginine (SDMA) concentrations in cheetahs (Acinonyx jubatus).\" 623 (2018)","DOI":"10.1638\/2017-0056.1"},{"key":"31","unstructured":"MT Walsh  and GD Bossart  \"Zoo and wild animal medicine, Volume 7, Current therapy.\"  \"Manatee medicine.\" 516 (1999)"},{"key":"32","doi-asserted-by":"crossref","unstructured":"G Zhang, R Mandral, DS Wishart, et al.  \"Front Vet Sci.\"  8, \"A multi-platform metabolomics approach identifies urinary metabolite signatures that differentiate ketotic from healthy dairy cows.\" 1 (2021)","DOI":"10.3389\/fvets.2021.595983"},{"key":"33","doi-asserted-by":"crossref","unstructured":"G Zwierchowski, G Zhang, R Mandral, et al.  \"Res Vet Sci.\"  129, \"Mass-spec-based urinary metabotyping around parturition identifies screening biomarkers for subclinical mastitis in dairy cows.\" 39 (2020)","DOI":"10.1016\/j.rvsc.2020.01.001"}],"container-title":["Journal of Zoo and Wildlife Medicine"],"original-title":[],"deposited":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T12:41:04Z","timestamp":1688733664000},"score":1,"resource":{"primary":{"URL":"https:\/\/bioone.org\/journals\/journal-of-zoo-and-wildlife-medicine\/volume-54\/issue-2\/2021-0133\/PRELIMINARY-EVALUATION-OF-SYMMETRIC-DIMETHYLARGININE-AS-A-BIOMARKER-OF-RENAL\/10.1638\/2021-0133.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,7]]},"references-count":33,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,6,1]]}},"URL":"https:\/\/doi.org\/10.1638\/2021-0133","relation":{},"ISSN":["1042-7260"],"issn-type":[{"value":"1042-7260","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7,7]]}}}