{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:59:07Z","timestamp":1791237547147,"version":"4.1.0"},"reference-count":20,"publisher":"American Association of Zoo Veterinarians","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Zoo and Wildlife Medicine"],"published-print":{"date-parts":[[2026,1,19]]},"abstract":"<jats:p>This study aimed to evaluate the safety and physiologic effects of sevoflurane anesthesia, induced with a face mask under manual restraint and maintained with intermittent positive pressure ventilation (IPPV) at 1 bpm, in captive juvenile green anacondas (Eunectes murinus). Anesthetic depth parameters were recorded from induction to recovery. Venous blood gas analysis, along with two-dimensional echocardiography were performed under manual restraint prior to induction and during anesthesia. Sevoflurane provided effective and consistent anesthesia, with rapid induction (3.6 \u00b1 0.9 min time to intubation), recovery (8.6 \u00b1 5.2 min to extubation), and minimal effects on spontaneous ventilation, but resulted in a significant decrease in venous base excess (P &lt; 0.001), bicarbonate (P = 0.02), as well as HR (P &lt; 0.001), and pulmonary trunk maximum velocity (P &lt; 0.001). Venous blood gas analysis indicated an anesthesia-related respiratory acidosis with a metabolic component, and echocardiography effectively demonstrated anesthesia-induced changes in the cardiovascular function of the snakes, consistent with a decreased cardiac output and blood pressure. Minimizing handling and adjusting the IPPV at a rate \u22651 bpm appears clinically warranted and may help address restraint-related metabolic acidosis, anesthesia-related respiratory acidosis, and probable hypotension in this species.<\/jats:p>","DOI":"10.1638\/2025-0040","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T05:48:16Z","timestamp":1768801696000},"page":"87-93","source":"Crossref","is-referenced-by-count":0,"title":["SEVOFLURANE ANESTHESIA IN JUVENILE GREEN ANACONDAS (EUNECTES MURINUS): EFFICACY AND EFFECTS ON BLOOD GAS AND ECHOCARDIOGRAPHIC PARAMETERS"],"prefix":"10.1638","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4225-7682","authenticated-orcid":false,"given":"Pierre","family":"Huberdeau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Lobko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Laidebeure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milan","family":"Thorel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"L\u00e9cu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1213","reference":[{"key":"10","doi-asserted-by":"crossref","unstructured":"L Kristensen, CL Malte, H Malte, et al.  \"Comp Biochem Physiol A Mol Integr Physiol.\"  271, \"Obesity prolongs induction 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Dutra, AB Carregaro, et al.  \"Am J Vet Med Assoc.\"  84, \"The fraction of inspired oxygen does not affect the time to extubation in mechanically ventilated, sevoflurane-anesthetized green sea turtles (Chelonia mydas). ajvr.\" (2023)","DOI":"10.2460\/ajvr.23.01.0008"},{"key":"11","doi-asserted-by":"crossref","unstructured":"C Mans, KK Sladky, J Schumacher,  \"Mader's reptile and amphibian medicine and surgery.\"  \"General anesthesia.\" 447.e2 (2019)","DOI":"10.1016\/B978-0-323-48253-0.00049-0"},{"key":"13","doi-asserted-by":"crossref","unstructured":"CA Mosley, D Dyson, DA Smith,  \"Vet Anaesth Analg.\"  31, \"The cardiovascular dose\u2013response effects of isoflurane alone and combined with butorphanol in the green iguana (Iguana iguana).\" 64 (2004)","DOI":"10.1111\/j.1467-2995.2004.00135.x"},{"key":"14","doi-asserted-by":"crossref","unstructured":"GM Oda, CAC Leite, AS Abe, et al.  \"Respir Physiol Neurobiol.\"  294, \"Effects of different levels of hypoxia and hypercarbia on 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