{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T17:08:09Z","timestamp":1748452089617},"reference-count":30,"publisher":"American Society of Parasitologists","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Parasitology"],"published-print":{"date-parts":[[2020,9,8]]},"DOI":"10.1645\/18-184","type":"journal-article","created":{"date-parts":[[2020,9,8]],"date-time":"2020-09-08T08:36:36Z","timestamp":1599554196000},"page":"564","source":"Crossref","is-referenced-by-count":5,"title":["Regulation of Proinflammatory Enzymes by Peroxisome Proliferator\u2013Activated Receptor Gamma in Astroglia Infected with Toxoplasma gondii"],"prefix":"10.1645","volume":"106","author":[{"given":"Ling-Yuh","family":"Shyu","sequence":"first","affiliation":[{"name":"Department of Parasitology, Chung Shan Medical University, 110, Section 1, Chien-Kuo North Road, Taichung 402, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ke-Min","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Chung Shan Medical University, 110, Section 1, Chien-Kuo North Road, Taichung 402, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-You","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Chung Shan Medical University, 110, Section 1, Chien-Kuo North Road, Taichung 402, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih-Chan","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Chung Shan Medical University, 110, Section 1, Chien-Kuo North Road, Taichung 402, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1220","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"L. S. Assun\u00e7\u00e3o, K. G. Magalh\u00e3es, A. B. Carneiro, et al. \"Biochimica et Biophysica Acta.\" 1862, \"Schistosomal-derived lysophosphatidylcholine triggers M2 polarization of macrophages through PPAR\u03b3 dependent mechanisms.\" 246 (2017)","DOI":"10.1016\/j.bbalip.2016.11.006"},{"key":"2","doi-asserted-by":"crossref","unstructured":"Y. Benesov\u00e1, A. Vasku, H. Novotn\u00e1, et al. \"Multiple Sclerosis Journal.\" 15, \"Matrix metalloproteinase-9 and matrix metalloproteinase-2 as bio-markers of various courses in multiple sclerosis.\" 316 (2009)","DOI":"10.1177\/1352458508099482"},{"key":"3","doi-asserted-by":"crossref","unstructured":"T. Breidert, J. Callebert, M. T. Heneka, et al. \"Journal of Neurochemistry.\" 82, \"Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease.\" 615 (2002)","DOI":"10.1046\/j.1471-4159.2002.00990.x"},{"key":"4","doi-asserted-by":"crossref","unstructured":"K. M. Chen, H. H. Lee, K. H. Lu, et al. \"International Journal for Parasitology.\" 34, \"Association of matrix metalloproteinase-9 and Purkinje cell degeneration in mouse cerebellum caused by Angiostrongylus cantonensis.\" 1147 (2004)","DOI":"10.1016\/j.ijpara.2004.07.004"},{"key":"5","doi-asserted-by":"crossref","unstructured":"D. L. Feinstein, E. Galea, V. Gavrilyuk, et al. \"Annals of Neurology.\" 51, \"Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis.\" 694 (2002)","DOI":"10.1002\/ana.10206"},{"key":"6","doi-asserted-by":"crossref","unstructured":"M. T. Heneka, T. Klockgether, D. L. Feinstein, \"Journal of Neuroscience.\" 20, \"Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide expression and cell death in vivo.\" 6862 (2000)","DOI":"10.1523\/JNEUROSCI.20-18-06862.2000"},{"key":"7","doi-asserted-by":"crossref","unstructured":"E. Hovsepian, G. A. Mirkin, F. Penas, et al. \"International Journal for Parasitology.\" 41, \"Modulation of inflammatory response and parasitism by 15-Deoxy-\u0394(12,14) prostaglandin J(2) in Trypanosoma cruzi\u2013infected cardiomyocytes.\" 553 (2011)","DOI":"10.1016\/j.ijpara.2010.12.002"},{"key":"8","doi-asserted-by":"crossref","unstructured":"J. Y. Kim, M. H. Ahn, H. O. Song, et al. \"Korean Journal of Parasitology.\" 44, \"Involvement of MAPK activation in chemokine or COX-2 productions by Toxoplasma gondii.\" 197 (2006)","DOI":"10.3347\/kjp.2006.44.3.197"},{"key":"9","doi-asserted-by":"crossref","unstructured":"G. E. Landreth and M. T. Heneka \"Neurobiology of Aging.\" 22, \"Anti-inflammatory actions of peroxisome proliferator-activated receptor gamma agonists in Alzheimer's disease.\" 937 (2001)","DOI":"10.1016\/S0197-4580(01)00296-2"},{"key":"10","doi-asserted-by":"crossref","unstructured":"C. Y. Lu and S. C. Lai \"Acta Tropica.\" 125, \"Matrix metalloproteinase-2 and -9 lead to fibronectin degradation in astroglia infected with Toxoplasma gondii.\" 320 (2013a)","DOI":"10.1016\/j.actatropica.2012.11.002"},{"key":"11","doi-asserted-by":"crossref","unstructured":"C. Y. Lu and S. C. Lai \"Acta Tropica.\" 127, \"Induction of MMP-2 and -9 via Erk1\/2-NF-\u03baB pathway in human astroglia infected with Toxoplasma gondii.\" 14 (2013b)","DOI":"10.1016\/j.actatropica.2013.03.004"},{"key":"12","doi-asserted-by":"crossref","unstructured":"C. Matte, G. Maion, W. Mourad, et al. \"Parasite Immunology.\" 23, \"Leishmania donovani\u2013induced macrophages cyclooxygenase-2 and prostaglandin E2 synthesis.\" 177 (2001)","DOI":"10.1046\/j.1365-3024.2001.00372.x"},{"key":"13","doi-asserted-by":"crossref","unstructured":"J. Pan, J. L. Jin, H. M. Ge, et al. \"Journal of Neuroinflammation.\" 12, \"Malibatol A regulates microglia M1\/M2 polarization in experimental stroke in a PPAR\u03b3-dependent manner.\" 51 (2015)","DOI":"10.1186\/s12974-015-0270-3"},{"key":"14","doi-asserted-by":"crossref","unstructured":"F. Penas, G. A. Mirkin, M. Vera, et al. \"Biochimica et Biophysica Acta.\" 1852, \"Treatment in vitro with PPAR\u03b1 and PPAR\u03b3 ligands drives M1-to-M2 polarization of macrophages from T. cruzi\u2013infected mice.\" 893 (2015)","DOI":"10.1016\/j.bbadis.2014.12.019"},{"key":"15","doi-asserted-by":"crossref","unstructured":"F. N. Penas, \u00c1. C. Cevey, S. Siffo, et al. \"Experimental Parasitology.\" 170, \"Hepatic injury associated with Trypanosoma cruzi infection is attenuated by treatment with 15-deoxy-\u039412,14 prostaglandin J2.\" 100 (2016)","DOI":"10.1016\/j.exppara.2016.09.015"},{"key":"16","doi-asserted-by":"crossref","unstructured":"C. F. Pereira, L. A. Boven, J. Middel, et al. \"Journal of Leukocyte Biology.\" 68, \"Induction of cyclooxygenase-2 expression during HIV-1-infected monocyte-derived macrophage and human brain microvascular endothelial cell interactions.\" 423 (2000)","DOI":"10.1189\/jlb.68.3.423"},{"key":"17","doi-asserted-by":"crossref","unstructured":"P. K. Peterson, G. Gekker, S. Hu, et al. \"Journal of Infectious Diseases.\" 171, \"Human astrocytes inhibit intracellular multiplication of Toxoplasma gondii by a nitric oxide\u2013mediated mechanism.\" 516 (1995)","DOI":"10.1093\/infdis\/171.2.516"},{"key":"18","doi-asserted-by":"crossref","unstructured":"M. Ricote, A. C. Li, T. M. Willson, et al. \"Nature.\" 391, \"The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation.\" 79 (1998)","DOI":"10.1038\/34178"},{"key":"19","doi-asserted-by":"crossref","unstructured":"A. B. Sabin and P. K. Olitsky \"Science.\" 85, \"Toxoplasma and obligate intracellular parasitism.\" 336 (1937)","DOI":"10.1126\/science.85.2205.336"},{"key":"20","doi-asserted-by":"crossref","unstructured":"K. Saijo, A. Crotti, C. K. Glass, \"Glia.\" 61, \"Regulation of microglia and deactivation by nuclear receptors.\" 104 (2013)","DOI":"10.1002\/glia.22423"},{"key":"21","doi-asserted-by":"crossref","unstructured":"H. Sayan-Ozacmak, V. H. Ozacmak, F. Barut, et al. \"Current Neurovascular Research.\" 8, \"Neuroprotective efficacy of the peroxisome proliferator-activated receptor-\u03b3 ligand in chronic cerebral hypoperfusion.\" 190 (2011)","DOI":"10.2174\/156720211796558087"},{"key":"22","doi-asserted-by":"crossref","unstructured":"T. M. Scharton-Kersten, G. Yap, J. Magram, et al. \"Journal of Experimental Medicine.\" 185, \"Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii.\" 1261 (1997)","DOI":"10.1084\/jem.185.7.1261"},{"key":"23","doi-asserted-by":"crossref","unstructured":"Y. W. Shih, S. T. Chien, P. S. Chen, et al. \"Cell Biochemistry and Biophysics.\" 58, \"Alpha-mangostin suppresses phorbol 12-myristate 13-acetate-induced MMP-2\/MMP-9 expressions via alphavbeta3 integrin\/FAK\/ERK and NF-kappaB signaling pathway in human lung adenocarcinoma A549 cells.\" 31 (2010)","DOI":"10.1007\/s12013-010-9091-2"},{"key":"24","unstructured":"B. D. Srinivasan and P. S. Kulkarni \"Investigative Ophthalmology & Visual Science.\" 19, \"The role of arachidonic acid metabolites in the mediation of the polymorphonuclear leukocyte response following corneal injury.\" 1087 (1980)"},{"key":"25","doi-asserted-by":"crossref","unstructured":"P. D. Storer, J. Xu, J. Chavis, et al. \"Journal of Neuroimmunology.\" 161, \"Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: Implications for multiple sclerosis.\" 113 (2005)","DOI":"10.1016\/j.jneuroim.2004.12.015"},{"key":"26","doi-asserted-by":"crossref","unstructured":"T. Tajima, T. Murata, K. Aritake, et al. \"Journal of Pharmacology and Experimental Therapeutics.\" 326, \"Lipopolysaccharide induces macrophage migration via prostaglandin D(2) and prostaglandin E(2).\" 493 (2008)","DOI":"10.1124\/jpet.108.137992"},{"key":"27","doi-asserted-by":"crossref","unstructured":"A. Taubert, H. Zahner, C. Hermosilla, \"Veterinary Parasitology.\" 142, \"Dynamics of transcription of immunomodulatory genes in endothelial cells infected with different coccidian parasites.\" 214 (2006)","DOI":"10.1016\/j.vetpar.2006.07.021"},{"key":"28","doi-asserted-by":"crossref","unstructured":"K. C. Wang, C. P. Tsai, C. L. Lee, et al. \"Clinical Science.\" 125, \"Alpha lipoic acid enhances endogenous peroxisome proliferator-activated receptor-\u03b3 to ameliorate experimental autoimmune encephalomyelitis.\" 329 (2013)","DOI":"10.1042\/CS20120560"},{"key":"29","doi-asserted-by":"crossref","unstructured":"E. H. Wilson and C. A. Hunter \"International Journal for Parasitology.\" 34, \"The role of astrocytes in the immunopathogenesis of toxoplasmic encephalitis.\" 543 (2004)","DOI":"10.1016\/j.ijpara.2003.12.010"},{"key":"30","doi-asserted-by":"crossref","unstructured":"J. M. Zolezzi, M. J. Santos, S. Bast\u00edas-Candia, et al. \"Biological Reviews of the Cambridge Philosophical Society.\" 92, \"PPARs in the central nervous system: roles in neurodegeneration and neuroinflammation.\" 2046 (2017)","DOI":"10.1111\/brv.12320"}],"container-title":["Journal of Parasitology"],"original-title":[],"deposited":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T09:10:03Z","timestamp":1668676203000},"score":1,"resource":{"primary":{"URL":"https:\/\/bioone.org\/journals\/journal-of-parasitology\/volume-106\/issue-5\/18-184\/Regulation-of-Proinflammatory-Enzymes-by-Peroxisome-ProliferatorActivated-Receptor-Gamma-in\/10.1645\/18-184.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,8]]},"references-count":30,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2020,9,1]]}},"URL":"https:\/\/doi.org\/10.1645\/18-184","relation":{},"ISSN":["0022-3395"],"issn-type":[{"value":"0022-3395","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9,8]]}}}