{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T08:39:54Z","timestamp":1761813594407,"version":"build-2065373602"},"reference-count":74,"publisher":"American Society of Parasitologists","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Parasitology"],"published-print":{"date-parts":[[2025,10,27]]},"DOI":"10.1645\/25-51","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T08:37:30Z","timestamp":1761813450000},"source":"Crossref","is-referenced-by-count":0,"title":["Fitness and Apoptotic Capacity of Buparvaquone-Resistant Theileria annulata Cell Lines with Mutations in Cytochrome B"],"prefix":"10.1645","volume":"111","author":[{"given":"S.","family":"Hacilarlioglu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Karagenc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Bak\u0131rc\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Aksulu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Koc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Eren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. B.","family":"Bilgic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1220","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"S. Al-Hamidhi, H. Tageldin, M. Weir, et al.  \"PLoS One.\"  10, \"Genetic diversity and population structure of Theileria annulata in Oman.\" e0139581 (2015)","DOI":"10.1371\/journal.pone.0139581"},{"key":"2","doi-asserted-by":"publisher","unstructured":"Q. Ali, O. Zahid, M. Mhadhbi, et al.  \"International Journal for Parasitology: Drugs and Drug Resistance.\"  20, \"Genetic characterisation of the Theileria annulata cytochrome b locus and its impact on buparvaquone resistance in bovine.\" 65 (2022)","DOI":"10.1016\/j.ijpddr.2022.08.004"},{"key":"3","doi-asserted-by":"publisher","unstructured":"L. K. Basco,  \"Pathogens.\"  12, \"Cultivation of asexual intraerythrocytic stages of Plasmodium falciparum.\" 900 (2023)","DOI":"10.3390\/pathogens12070900"},{"key":"4","doi-asserted-by":"publisher","unstructured":"A. S. Bell, S. Huijben, K. P. Paaijmans, et al.  \"PLoS One.\"  7, \"Enhanced transmission of drug-resistant parasites to mosquitoes following drug treatment in rodent malaria.\" e37172 (2012)","DOI":"10.1371\/journal.pone.0037172"},{"key":"5","doi-asserted-by":"publisher","unstructured":"H. B. Bilgic, A. Aksulu, S. Bakirci, et al.  \"Veterinary Parasitology.\"  265, \"Infection dynamics of Theileria annulata over a disease season following cell line vaccination.\" 63 (2019)","DOI":"10.1016\/j.vetpar.2018.11.012"},{"key":"6","doi-asserted-by":"publisher","unstructured":"D. Birth, W. C. Kao, C. Hunte,  \"Nature Communications.\"  5, \"Structural analysis of atovaquone-inhibited cytochrome bc\n1 complex reveals the molecular basis of antimalarial drug action.\" 4029 (2014)","DOI":"10.1038\/ncomms5029"},{"key":"7","doi-asserted-by":"crossref","unstructured":"J. T. Bousema, C. J. Drakeley, P. F. Mens, et al.  \"American Journal of Tropical Medicine and Hygiene.\"  78, \"Increased Plasmodium falciparum gametocyte production in mixed infections with P. malariae.\" 442 (2008)","DOI":"10.4269\/ajtmh.2008.78.442"},{"key":"8","doi-asserted-by":"publisher","unstructured":"C. L. Boutwell, C. F. Rowley, M. Essex,  \"Journal of Virology.\"  83, \"Reduced viral replication capacity of human immunodeficiency virus type 1 subtype C caused by cytotoxic-T-lymphocyte escape mutations in HLA-B57 epitopes of capsid protein.\" 2460 (2009)","DOI":"10.1128\/JVI.01970-08"},{"key":"9","unstructured":"C. G. Brown,  \"Parassitologia.\"  32, \"Control of tropical theileriosis (Theileria annulata infection) of cattle.\" 23 (1990)"},{"key":"10","unstructured":"C. G. D. Brown,  \"Vitro Methods of Parasite Cultivation.\"  \"Theileriidae.\" 230 (1987)"},{"key":"11","doi-asserted-by":"publisher","unstructured":"E. Chatanga, E. Mosssad, Abdo Abubaker H., et al.  \"Acta Tropica.\"  191, \"Evidence of multiple point mutations in Theileria annulata cytochrome b gene incriminated in buparvaquone treatment failure.\" 128 (2019)","DOI":"10.1016\/j.actatropica.2018.12.041"},{"key":"12","doi-asserted-by":"publisher","unstructured":"M. Chaussepied  and G. Langsley  \"Research in Immunology.\"  147, \"Theileria transformation of bovine leukocytes: A parasite model for the study of lymphoproliferation.\" 127 (1996)","DOI":"10.1016\/0923-2494(96)83165-8"},{"key":"13","doi-asserted-by":"publisher","unstructured":"M. Cong, W. Heneine, Garcia-Lerma J. G.,  \"Journal of Virology.\"  81, \"The fitness cost of mutations associated with human immunodeficiency virus type 1 drug resistance is modulated by mutational interactions.\" 3037 (2007)","DOI":"10.1128\/JVI.02712-06"},{"key":"14","unstructured":"G. H. Coombs  and S. L. Croft  \"Symposia of the British Society for Parasitology.\"  \"Molecular basis of drug design and resistance.\" 81 (1997)"},{"key":"15","doi-asserted-by":"publisher","unstructured":"J. C. De Roode, R. Culleton, A. S. Bell, et al.  \"Malaria Journal.\"  3, \"Competitive release of drug resistance following drug treatment of mixed Plasmodium chabaudi infections.\" 33 (2004)","DOI":"10.1186\/1475-2875-3-33"},{"key":"16","doi-asserted-by":"publisher","unstructured":"S. K. Dhingra, S. J. Gabryszewski, Small-Saunders J. L., et al.  \"mBio.\"  10, \"Global spread of mutant PfCRT and its pleiotropic impact on Plasmodium falciparum multidrug resistance and fitness.\" e02731 (2019)","DOI":"10.1128\/mBio.02731-18"},{"key":"17","doi-asserted-by":"publisher","unstructured":"D. Dobbelaere  and V. Heussler  \"Annual Review of Microbiology.\"  53, \"Transformation of leukocytes by Theileria parva and T. annulata.\" 1 (1999)","DOI":"10.1146\/annurev.micro.53.1.1"},{"key":"18","doi-asserted-by":"publisher","unstructured":"D. A. Dobbelaere  and S. Rottenberg  \"Current Opinion in Microbiology.\"  6, \"Theileria-induced leukocyte transformation.\" 377 (2003)","DOI":"10.1016\/S1369-5274(03)00085-7"},{"key":"19","doi-asserted-by":"publisher","unstructured":"M. Ender, N. Mccallum, R. Adhikari, et al.  \"Antimicrobial Agents and Chemotherapy.\"  48, \"Fitness cost of SCCmec and methicillin resistance levels in Staphylococcus aureus.\" 2295 (2004)","DOI":"10.1128\/AAC.48.6.2295-2297.2004"},{"key":"20","doi-asserted-by":"publisher","unstructured":"I. Felger  and H. P. Beck  \"Trends in Parasitology.\"  24, \"Fitness costs of resistance to antimalarial drugs.\" 331 (2008)","DOI":"10.1016\/j.pt.2008.05.004"},{"key":"21","doi-asserted-by":"publisher","unstructured":"L. M. Fohl  and D. S. Roos  \"Molecular Microbiology.\"  50, \"Fitness effects of DHFR-TS mutations associated with pyrimethamine resistance in apicomplexan parasites.\" 1319 (2003)","DOI":"10.1046\/j.1365-2958.2003.03756.x"},{"key":"22","doi-asserted-by":"publisher","unstructured":"S. J. Gabryszewski, C. Modchang, L. Musset, et al.  \"Molecular Biology and Evolution.\"  33, \"Combinatorial genetic modeling of pfcrt-mediated drug resistance evolution in Plasmodium falciparum.\" 1554 (2016)","DOI":"10.1093\/molbev\/msw037"},{"key":"23","doi-asserted-by":"publisher","unstructured":"Y. Gavrieli, Y. Sherman, Ben-Sasson S. A.,  \"Journal of Cell Biology.\"  119, \"Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.\" 493 (1992)","DOI":"10.1083\/jcb.119.3.493"},{"key":"24","unstructured":"\"Dose\u2013response analysis with nonlinear regression test performed using GraphPad Prism version 5.03 for Windows.\"  (2009)"},{"key":"25","doi-asserted-by":"publisher","unstructured":"J. Guergnon, F. Dessauge, G. Langsley, et al.  \"Biochimie.\"  85, \"Apoptosis of Theileria-infected lymphocytes induced upon parasite death involves activation of caspases 9 and 3.\" 771 (2003)","DOI":"10.1016\/j.biochi.2003.09.013"},{"key":"26","doi-asserted-by":"publisher","unstructured":"S. Hacilarlioglu, H. B. Bilgic, S. Bakirci, et al.  \"PLoS One.\"  18, \"Selection of genotypes harbouring mutations in the cytochrome b gene of Theileria annulata is associated with resistance to buparvaquone.\" e0279925 (2023)","DOI":"10.1371\/journal.pone.0279925"},{"key":"27","doi-asserted-by":"publisher","unstructured":"J. Han, Y. Wang, O. Sahin, et al.  \"Frontiers in Cellular and Infection Microbiology.\"  2, \"A fluoroquinolone resistance associated mutation in gyrA affects DNA supercoiling in Campylobacter jejuni.\" 21 (2012)","DOI":"10.3389\/fcimb.2012.00021"},{"key":"28","doi-asserted-by":"publisher","unstructured":"W. E. Harrington, T. K. Mutabingwa, A. Muehlenbachs, et al.  \"Proceedings of the National Academy of Sciences of the United States of America.\"  106, \"Competitive facilitation of drug-resistant Plasmodium falciparum malaria parasites in pregnant women who receive preventive treatment.\" 9027 (2009)","DOI":"10.1073\/pnas.0901415106"},{"key":"29","doi-asserted-by":"publisher","unstructured":"R. Hashemi-Fesharki,  \"Research in Veterinary Science.\"  50, \"Chemotherapeutic value of parvaquone and buparvaquone against Theileria annulata infection of cattle.\" 204 (1991)","DOI":"10.1016\/0034-5288(91)90107-y"},{"key":"30","doi-asserted-by":"publisher","unstructured":"I. M. Hastings,  \"Parasitology.\"  115, \"A model for the origins and spread of drug-resistant malaria.\" 133 (1997)","DOI":"10.1017\/s0031182097001261"},{"key":"31","doi-asserted-by":"publisher","unstructured":"V. T. Heussler, P. K\u00fcenzi, S. Rottenberg,  \"International Journal for Parasitology.\"  31, \"Inhibition of apoptosis by intracellular protozoan parasites.\" 1166 (2001)","DOI":"10.1016\/s0020-7519(01)00271-5"},{"key":"32","doi-asserted-by":"publisher","unstructured":"V. T. Heussler, J. Machado, P. C. Fernandez, et al.  \"Proceedings of the National Academy of Sciences of the United States of America.\"  96, \"The intracellular parasite Theileria parva protects infected T cells from apoptosis.\" 7312 (1999)","DOI":"10.1073\/pnas.96.13.7312"},{"key":"33","doi-asserted-by":"publisher","unstructured":"S. Huijben, B. H. K. Chan, W. A. Nelson, et al.  \"Evolution, Medicine, and Public Health.\"  2018, \"The impact of within-host ecology on the fitness of a drug-resistant parasite.\" 127 (2018)","DOI":"10.1093\/emph\/eoy016"},{"key":"34","doi-asserted-by":"publisher","unstructured":"S. Huijben, W. A. Nelson, A. R. Wargo, et al.  \"Evolution.\"  64, \"Chemotherapy, within-host ecology and the fitness of drug-resistant malaria parasites.\" 2952 (2010)","DOI":"10.1111\/j.1558-5646.2010.01068.x"},{"key":"35","doi-asserted-by":"publisher","unstructured":"S. Huijben, D. G. Sim, W. A. Nelson, et al.  \"Journal of Evolutionary Biology.\"  24, \"The fitness of drug-resistant malaria parasites in a rodent model: Multiplicity of infection.\" 2410 (2011)","DOI":"10.1111\/j.1420-9101.2011.02369.x"},{"key":"36","doi-asserted-by":"crossref","unstructured":"A. D. Irvin,  \"Parasitology Today.\"  1, \"Immunity in theileriosis.\" 124 (1985)","DOI":"10.1016\/0169-4758(85)90056-0"},{"key":"37","doi-asserted-by":"publisher","unstructured":"M. Korsinczky, N. Chen, B. Kotecka, et al.  \"Antimicrobial Agents and Chemotherapy.\"  44, \"Mutations in Plasmodium falciparum cytochrome b that are associated with atovaquone resistance are located at a putative drug-binding site.\" 2100 (2000)","DOI":"10.1128\/AAC.44.8.2100-2108.2000"},{"key":"38","doi-asserted-by":"publisher","unstructured":"M. J. Mackinnon  and I. M. Hastings  \"Transactions of the Royal Society of Tropical Medicine and Hygiene.\"  92, \"The evolution of multiple drug resistance in malaria parasites.\" 188 (1998)","DOI":"10.1016\/s0035-9203(98)90745-3"},{"key":"39","doi-asserted-by":"publisher","unstructured":"L. C. Mathieu, H. Cox, A. M. Early, et al.  \"eLife.\"  9, \"Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance.\" e51015 (2020)","DOI":"10.7554\/eLife.51015"},{"key":"40","doi-asserted-by":"publisher","unstructured":"M. Mhadhbi, M. Chaouch, K. Ajroud, et al.  \"PLoS One.\"  10, \"Sequence polymorphism of cytochrome b gene in Theileria annulata Tunisian isolates and its association with buparvaquone treatment failure.\" e0129678 (2015)","DOI":"10.1371\/journal.pone.0129678"},{"key":"41","doi-asserted-by":"publisher","unstructured":"M. Mhadhbi, A. Naouach, A. Boumiza, et al.  \"Veterinary Parasitology.\"  169, \"In vivo evidence for the resistance of Theileria annulata to buparvaquone.\" 241 (2010)","DOI":"10.1016\/j.vetpar.2010.01.013"},{"key":"42","doi-asserted-by":"publisher","unstructured":"J. E. Moss, A. O. Aliprantis, A. Zychlinsky,  \"International Review of Cytology.\"  187, \"The regulation of apoptosis by microbial pathogens.\" 203 (1999)","DOI":"10.1016\/s0074-7696(08)62419-5"},{"key":"43","doi-asserted-by":"publisher","unstructured":"A. K. Nehra, A. D. Moudgil, A. Kumari, et al.  \"Acta Tropica.\"  250, \"Population genetic characterization of Theileria annulata based on the cytochrome b gene, with genetic insights into buparvaquone susceptibility in Haryana (India).\" 107103 (2024)","DOI":"10.1016\/j.actatropica.2023.107103"},{"key":"44","doi-asserted-by":"publisher","unstructured":"S. C. Nkhoma, A. O. A. Ahmed, D. Porier, et al.  \"Molecular and Biochemical Parasitology.\"  254, \"Dynamics of parasite growth in genetically diverse Plasmodium falciparum isolates.\" 111552 (2023)","DOI":"10.1016\/j.molbiopara.2023.111552"},{"key":"45","unstructured":"R. A. I. Norval, B. D. Perry, A. S. Young,  \"The Epidemiology of Theileriosis in Africa.\"  481 (1992)"},{"key":"46","unstructured":"C. O'brien, P. P. Henrich, N. Passi, et al.  \"Current Opinion in Infectious Diseases.\"  24, \"Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum.\" 570 (2011)"},{"key":"47","doi-asserted-by":"publisher","unstructured":"E. Ochong, P. K. Tumwebaze, O. Byaruhanga, et al.  \"Antimicrobial Agents and Chemotherapy.\"  57, \"Fitness consequences of Plasmodium falciparum pfmdr1 polymorphisms inferred from ex vivo culture of Ugandan parasites.\" 4245 (2013)","DOI":"10.1128\/AAC.00161-13"},{"key":"48","doi-asserted-by":"publisher","unstructured":"A. M. Oduola, O. A. Ogundahunsi, L. A. Salako,  \"Journal of Protozoology.\"  39, \"Continuous cultivation and drug susceptibility testing of Plasmodium falciparum in a malaria endemic area.\" 605 (1992)","DOI":"10.1111\/j.1550-7408.1992.tb04858.x"},{"key":"49","doi-asserted-by":"publisher","unstructured":"C. B. Ogbunugafor  and D. Hartl  \"Malaria Journal.\"  15, \"A pivot mutation impedes reverse evolution across an adaptive landscape for drug resistance in Plasmodium vivax.\" 40 (2016)","DOI":"10.1186\/s12936-016-1090-3"},{"key":"50","doi-asserted-by":"publisher","unstructured":"J. M. Peters, N. Chen, M. Gatton, et al.  \"Antimicrobial Agents and Chemotherapy.\"  46, \"Mutations in cytochrome b resulting in atovaquone resistance are associated with loss of fitness in Plasmodium falciparum.\" 2435 (2002)","DOI":"10.1128\/AAC.46.8.2435-2441.2002"},{"key":"51","doi-asserted-by":"publisher","unstructured":"P. Preechapornkul, M. Imwong, K. Chotivanich, et al.  \"Antimicrobial Agents and Chemotherapy.\"  53, \"Plasmodium falciparum pfmdr1 amplification, mefloquine resistance, and parasite fitness.\" 1509 (2009)","DOI":"10.1128\/AAC.00241-08"},{"key":"52","doi-asserted-by":"publisher","unstructured":"A. F. Read, T. Day, S. Huijben,  \"Proceedings of the National Academy of Sciences of the United States of America.\"  108, \"The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy.\" 10871 (2011)","DOI":"10.1073\/pnas.1100299108"},{"key":"53","doi-asserted-by":"publisher","unstructured":"H. B. Reilly, H. Wang, J. A. Steuter, et al.  \"International Journal for Parasitology.\"  37, \"Quantitative dissection of clone-specific growth rates in cultured malaria parasites.\" 1599 (2007)","DOI":"10.1016\/j.ijpara.2007.05.003"},{"key":"54","doi-asserted-by":"publisher","unstructured":"P. M. Robinson,  \"Tropical Animal Health and Production.\"  14, \"Theileria annulata and its transmission\u2014A review.\" 3 (1982)","DOI":"10.1007\/BF02281092"},{"key":"55","doi-asserted-by":"publisher","unstructured":"V. E. Rosario, R. Hall, D. Walliker, et al.  \"Lancet.\"  1, \"Persistence of drug-resistant malaria parasites.\" 185 (1978)","DOI":"10.1016\/s0140-6736(78)90616-5"},{"key":"56","doi-asserted-by":"publisher","unstructured":"X. Segovia, B. Srivastava, Serrato-Arroyo S., et al.  \"Malaria Journal.\"  24, \"Assessing fitness costs in malaria parasites: A comprehensive review and implications for drug resistance management.\" 65 (2025)","DOI":"10.1186\/s12936-025-05286-w"},{"key":"57","doi-asserted-by":"publisher","unstructured":"H. Sharifiyazdi, F. Namazi, A. Oryan, et al.  \"Veterinary Parasitology.\"  187, \"Point mutations in the Theileria annulata cytochrome b gene is associated with buparvaquone treatment failure.\" 431 (2012)","DOI":"10.1016\/j.vetpar.2012.01.016"},{"key":"58","doi-asserted-by":"publisher","unstructured":"B. R. Shiels, C. Mcdougall, A. Tait, et al.  \"Parasite Immunology.\"  8, \"Identification of infection-associated antigens in Theileria annulata transformed cells.\" 69 (1986)","DOI":"10.1111\/j.1365-3024.1986.tb00834.x"},{"key":"59","doi-asserted-by":"publisher","unstructured":"C. J. Shinondo, H. N. Lanners, Lowrie R. C., et al.  \"Experimental Parasitology.\"  78, \"Effect of pyrimethamine resistance on sporogony in a Plasmodium berghei\/Anopheles stephensi model.\" 194 (1994)","DOI":"10.1006\/expr.1994.1019"},{"key":"60","doi-asserted-by":"publisher","unstructured":"T. Smith, I. Felger, M. Tanner, et al.  \"Transactions of the Royal Society of Tropical Medicine and Hygiene.\"  93, \"Premunition in Plasmodium falciparum infection: Insights from the epidemiology of multiple infections.\" S59 (1999)","DOI":"10.1016\/s0035-9203(99)90329-2"},{"key":"61","doi-asserted-by":"crossref","unstructured":"S. Tajeri, D. Chattopadhyay, G. Langsley, et al.  \"PLoS One.\"  19, \"A Theileria annulata parasite with a single mutation, methionine 128 to isoleucine (M128I), in cytochrome b is resistant to buparvaquone.\" e0299002 (2024)","DOI":"10.1371\/journal.pone.0299002"},{"key":"62","doi-asserted-by":"publisher","unstructured":"L. H. Taylor, D. Walliker, A. F. Read,  \"Proceedings of the Royal Society of London. Series B, Biological Sciences.\"  264, \"Mixed-genotype infections of malaria parasites: Within-host dynamics and transmission success of competing clones.\" 927 (1997)","DOI":"10.1098\/rspb.1997.0128"},{"key":"63","doi-asserted-by":"publisher","unstructured":"A. R. Tirrell, K. M. Vendrely, L. A. Checkley, et al.  \"Malaria Journal.\"  18, \"Pairwise growth competitions identify relative fitness relationships among artemisinin-resistant Plasmodium falciparum field isolates.\" 295 (2019)","DOI":"10.1186\/s12936-019-2934-4"},{"key":"64","doi-asserted-by":"publisher","unstructured":"I. Valsecchi, E. Mellado, R. Beau, et al.  \"Antimicrobial Agents and Chemotherapy.\"  59, \"Fitness studies of azole-resistant strains of Aspergillus fumigatus.\" 7866 (2015)","DOI":"10.1128\/AAC.01594-15"},{"key":"65","doi-asserted-by":"publisher","unstructured":"D. L. Vaux, G. Haecker, A. Strasser,  \"Cell.\"  76, \"An evolutionary perspective on apoptosis.\" 777 (1994)","DOI":"10.1016\/0092-8674(94)90350-6"},{"key":"66","doi-asserted-by":"publisher","unstructured":"M. A. Wacker, L. B. Turnbull, L. A. Walker, et al.  \"Malaria Journal.\"  11, \"Quantification of multiple infections of Plasmodium falciparum in vitro.\" 180 (2012)","DOI":"10.1186\/1475-2875-11-180"},{"key":"67","doi-asserted-by":"publisher","unstructured":"D. Walliker, P. Hunt, H. Babiker,  \"Acta Tropica.\"  94, \"Fitness of drug-resistant malaria parasites.\" 251 (2005)","DOI":"10.1016\/j.actatropica.2005.04.005"},{"key":"68","doi-asserted-by":"publisher","unstructured":"A. R. Wargo, De Roode J. C., S. Huijben, et al.  \"Proceedings of the Royal Society B: Biological Sciences.\"  274, \"Transmission stage investment of malaria parasites in response to in-host competition.\" 2629 (2007)","DOI":"10.1098\/rspb.2007.0873"},{"key":"69","doi-asserted-by":"publisher","unstructured":"W. Weir, Ben Miled L., T. Karagenc, et al.  \"Molecular and Biochemical Parasitology.\"  154, \"Genetic exchange and sub-structuring in Theileria annulata populations.\" 170 (2007)","DOI":"10.1016\/j.molbiopara.2007.04.015"},{"key":"70","doi-asserted-by":"publisher","unstructured":"O. Wiens, D. Xia, Von Schubert C., et al.  \"PLoS ONE.\"  9, \"Cell cycle-dependent phosphorylation of Theileria annulata schizont surface proteins.\" e103821 (2014)","DOI":"10.1371\/journal.pone.0103821"},{"key":"71","doi-asserted-by":"publisher","unstructured":"P. Wilairat, K. K\u00fcmpornsin, T. Chookajorn,  \"Medical Hypotheses.\"  90, \"Plasmodium falciparum malaria: Convergent evolutionary trajectories towards delayed clearance following artemisinin treatment.\" 19 (2016)","DOI":"10.1016\/j.mehy.2016.02.022"},{"key":"72","unstructured":"\"Guidelines for the Treatment of Malaria.\"  313 (2015)"},{"key":"73","unstructured":"\"World malaria report 2024.\"  (2024)"},{"key":"74","doi-asserted-by":"publisher","unstructured":"S. G. Yousef, El Balkemy F. A., El Damaty H. M.,  \"Pakistan Veterinary Journal.\"  40, \"Mutations in Theileria annulata cytochrome b gene associated with buparvaquone resistance in cattle, Egypt.\" 261 (2020)","DOI":"10.29261\/pakvetj\/2020.006"}],"container-title":["Journal of Parasitology"],"original-title":[],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T08:37:33Z","timestamp":1761813453000},"score":1,"resource":{"primary":{"URL":"https:\/\/bioone.org\/journals\/journal-of-parasitology\/volume-111\/issue-5\/25-51\/Fitness-and-Apoptotic-Capacity-of-Buparvaquone-Resistant-Theileria-annulata-Cell\/10.1645\/25-51.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,27]]},"references-count":74,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,10,1]]}},"URL":"https:\/\/doi.org\/10.1645\/25-51","relation":{},"ISSN":["0022-3395"],"issn-type":[{"value":"0022-3395","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10,27]]}}}