{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:53:06Z","timestamp":1791244386227,"version":"4.1.0"},"reference-count":18,"publisher":"Association of Avian Veterinarians (AAV)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Avian Medicine and Surgery"],"published-print":{"date-parts":[[2025,2,27]]},"abstract":"<jats:p>Two wild adult bald eagles (Haliaeetus leucocephalus) were presented to the University of Florida zoological medicine department on separate dates, both being unable to fly. One eagle had a fracture of the left humerus, and the second had no external injuries. Thoracic radiographs of both animals revealed cardiomegaly, and echocardiography revealed reduced systolic function. Both eagles were treated with oral pimobendan until recheck echocardiography documented normal systolic function. Several weeks after pimobendan was discontinued, the echocardiograms of both eagles showed normal systolic function and were considered normal. The transient nature of systolic dysfunction in these 2 eagles could be consistent with a stress-induced, Takotsubo cardiomyopathy-like phenotype although traumatic myocarditis or adverse anesthetic reactions must also be considered.<\/jats:p>","DOI":"10.1647\/avianms-d-23-00055","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T05:17:46Z","timestamp":1741065466000},"page":"39-45","source":"Crossref","is-referenced-by-count":2,"title":["Takotsubo Cardiomyopathy-like Transient Systolic Dysfunction in Two Bald Eagles (Haliaeetus leucocephalus)"],"prefix":"10.1647","volume":"39","author":[{"given":"Samantha","family":"Scott","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Aherne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Georges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darcy B.","family":"Adin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James F. X.","family":"Wellehan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1222","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"MP Jones, AL Kristopher, C Cray,  \"J Avian Med Surgery.\"  28, \"Reference intervals, longitudinal analyses, and index of individuality of commonly measured laboratory variables in captive bald eagles (Haliaeetus leucocephalus).\" 118 (2014)","DOI":"10.1647\/2013-001"},{"key":"2","doi-asserted-by":"crossref","unstructured":"K. Plumlee,  \"Clinical Veterinary Toxicology.\"  \"Metals and minerals.\" 193 (2004)","DOI":"10.1016\/B0-32-301125-X\/50025-X"},{"key":"4","unstructured":"M Pees, M Krautwald-Junghanns, J Straub,  \"Clinical Avian Medicine.\"  16, \"Evaluating and treating the cardiovascular system. Harrison GJ, Lightfoot TL.\" 379 (2006)"},{"key":"5","doi-asserted-by":"crossref","unstructured":"DS Guzman, H Beaufrere, B KuKanich,  \"J Avian Med Surg.\"  28, \"Pharmacokinetics of single oral dose of pimobendan in Hispaniolan Amazon parrots (Amazona ventralis).\" 95 (2014)","DOI":"10.1647\/2012-061"},{"key":"6","doi-asserted-by":"crossref","unstructured":"J Brandao, CA Reynolds, H Beaufrere,  \"J Am Vet Med Assoc.\"  249, \"Cardiomyopathy in a Harris hawk (Parabuteo unicinctus).\" 221 (2016)","DOI":"10.2460\/javma.249.2.221"},{"key":"7","doi-asserted-by":"crossref","unstructured":"M Daigneault, KE Harr, KM Dean,  \"Ecotoxicol Environ Saf.\"  141, \"Assay validation of the cardiac isoform of troponin I in double crested cormorant (Phalacrocorax auritus) plasma for diagnosis of cardiac damage.\" 52 (2017)","DOI":"10.1016\/j.ecoenv.2017.03.006"},{"key":"9","doi-asserted-by":"crossref","unstructured":"B Boyd  and T Solh  \"JAAPA.\"  33, \"Takotsubo cardiomyopathy: review of broken heart syndrome.\" 24 (2020)","DOI":"10.1097\/01.JAA.0000654368.35241.fc"},{"key":"10","doi-asserted-by":"crossref","unstructured":"HZ Amin, LZ Amin, A Pradipta,  \"J Med Life.\"  13, \"Takotsubo cardiomyopathy: a brief review.\" 3 (2020)","DOI":"10.25122\/jml-2018-0067"},{"key":"11","doi-asserted-by":"crossref","unstructured":"A Prasad, A Lerman, CS Rihal,  \"Am Heart J.\"  155, \"Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction.\" 408 (2008)","DOI":"10.1016\/j.ahj.2007.11.008"},{"key":"12","doi-asserted-by":"crossref","unstructured":"RM Shah, VK Kodumuri, R Bhuriya,  \"Am J Ther.\"  19, \"Fixing the \u201cbroken heart\u201d: pharmacologic implications.\" e105 (2012)","DOI":"10.1097\/MJT.0b013e3181f2ab74"},{"key":"13","doi-asserted-by":"crossref","unstructured":"JE. Madias,  \"Echocardiography.\"  30, \"Two cases of reversible left ventricular hypertrophy during recovery from takotsubo cardiomyopathy: hypertrophy or myocardial edema after an attack of takotsubo syndrome?\" 989 (2013)","DOI":"10.1111\/echo.12249"},{"key":"15","unstructured":"MC Tanner, JD Thomason, T Rooney,  \"Israel J Vet Med.\"  77, \"Takotsubo-like cardiomyopathy associated with capture myopathy in a zoo-kept, red-necked wallaby (Macropus rufogriseus).\" 44 (2022)"},{"key":"16","doi-asserted-by":"crossref","unstructured":"SC Oster, S Jung, R Moon,  \"J Exotic Pet Med.\"  29, \"Resolution of supraventricular arrhythmia using sotalol in an adult golden eagle (Aquila chrysaetos) with presumed atherosclerosis.\" 136 (2019)","DOI":"10.1053\/j.jepm.2018.10.004"},{"key":"17","doi-asserted-by":"crossref","unstructured":"B Pinamonti, E Alberti, A Cigalotto,  \"Am J Cardiol.\"  62, \"Echocardiographic findings in myocarditis.\" 285 (1988)","DOI":"10.1016\/0002-9149(88)90226-3"},{"key":"18","unstructured":"R Aguilar, V Smith, P Ogburn,  \"J Zoo Wild Med.\"  26, \"Arrhythmias associated with isoflurane anesthesia in bald eagles (Haliaeetus leucocephalus).\" 508 (1995)"},{"key":"14","doi-asserted-by":"crossref","unstructured":"J Novo Matos, N Pereira, T Glaus,  \"J Vet Intern Med.\"  32, \"Transient myocardial thickening in cats associated with heart failure.\" 48 (2018)","DOI":"10.1111\/jvim.14897"},{"key":"3","doi-asserted-by":"crossref","unstructured":"S Locke, D Johnson, J Shimp,  \"J Avian Med Surg.\"  34, \"Radiographic reference intervals of the cardiac silhouette width in the bald eagle (Haliaeetus leucocephalus).\" 260 (2020)","DOI":"10.1647\/1082-6742-34.3.260"},{"key":"8","doi-asserted-by":"crossref","unstructured":"PH Joyner, MP Jones, D Ward,  \"Am J Vet Res.\"  69, \"Induction and recovery characteristics and cardiopulmonary effects of sevoflurane and isoflurane in bald eagles.\" 13 (2008)","DOI":"10.2460\/ajvr.69.1.13"}],"container-title":["Journal of Avian Medicine and Surgery"],"original-title":[],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:02:04Z","timestamp":1791241324000},"score":1,"resource":{"primary":{"URL":"https:\/\/bioone.org\/journals\/journal-of-avian-medicine-and-surgery\/volume-39\/issue-1\/AVIANMS-D-23-00055\/Takotsubo-Cardiomyopathy-like-Transient-Systolic-Dysfunction-in-Two-Bald-Eagles\/10.1647\/AVIANMS-D-23-00055.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,27]]},"references-count":18,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,3,1]]}},"URL":"https:\/\/doi.org\/10.1647\/avianms-d-23-00055","relation":{},"ISSN":["1082-6742","1938-2871"],"issn-type":[{"value":"1082-6742","type":"print"},{"value":"1938-2871","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,27]]}}}