{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:53:01Z","timestamp":1791237181782,"version":"4.1.0"},"reference-count":30,"publisher":"Radiation Research Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiation Research"],"published-print":{"date-parts":[[2026,4,27]]},"abstract":"<jats:p>In the event of a criticality accident, there is a risk of high-dose exposure for affected individuals from a mixed gamma\u2013neutron radiation field. Dosimetry in such cases is complex and requires multiple approaches. Biodosimetry methods, especially the dicentric chromosome assay (DCA), the most established method, can significantly support triage and medical care decisions after a criticality incident. However, large-scale events need collaboration between laboratories to enable timely dose assessments using DCA. We conducted a comparison among three biodosimetry laboratories, focusing on DCA-based estimates of the total dose, including the specific gamma-ray dose and neutron-heavy-particle dose for blood samples irradiated in a mixed gamma\u2013neutron field. Although each laboratory used dose-effect curves derived from different radiation spectra and irradiation facilities, the dose estimates were acceptable, with relative deviations no greater than 21%. Overall, the study showed that collaborating between labs is feasible for individual dose estimation after a criticality accident.<\/jats:p>","DOI":"10.1667\/rade-25-00180.1","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T21:09:17Z","timestamp":1785877757000},"page":"122-129","source":"Crossref","is-referenced-by-count":1,"title":["Interlaboratory Comparison of the Dicentric Chromosome Assay for a Mixed Gamma\u2013Neutron Radiation Field"],"prefix":"10.1667","volume":"206","author":[{"given":"Jakub","family":"Vavra","sequence":"first","affiliation":[{"name":"National Radiation Protection Institute, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Ekendahl","sequence":"additional","affiliation":[{"name":"National Radiation Protection Institute, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Kotik","sequence":"additional","affiliation":[{"name":"National Radiation Protection Institute, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Davidkova","sequence":"additional","affiliation":[{"name":"National Radiation Protection Institute, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Beinke","sequence":"additional","affiliation":[{"name":"Bundeswehr Institute of Radiobiology, affiliated to the University of Ulm, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ursula","family":"Oestreicher","sequence":"additional","affiliation":[{"name":"Federal Office for Radiation Protection (BfS), Oberschleissheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Endesfelder","sequence":"additional","affiliation":[{"name":"Federal Office for Radiation Protection (BfS), Oberschleissheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Bucher","sequence":"additional","affiliation":[{"name":"Federal Office for Radiation Protection (BfS), Oberschleissheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ondrej","family":"Huml","sequence":"additional","affiliation":[{"name":"Czech Technical University in Prague, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johana","family":"Alaverdyan","sequence":"additional","affiliation":[{"name":"National Radiation Protection Institute, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Artur","family":"Sergunin","sequence":"additional","affiliation":[{"name":"National Radiation Protection Institute, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Slezakova","sequence":"additional","affiliation":[{"name":"National Radiation Protection Institute, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1243","reference":[{"key":"8","doi-asserted-by":"publisher","unstructured":"MA Bender  and PC Gooch  \"Proc Natl Acad Sci USA.\"  48, \"Types and rates of x-ray-induced chromosome aberrations in human blood irradiated in vitro.\" 522 (1962)","DOI":"10.1073\/pnas.48.4.522"},{"key":"1","doi-asserted-by":"crossref","unstructured":"T McLaughlin, S Monahan, N Pruvost, et al.  \"A review of criticality accidents.\"  (2000)","DOI":"10.2172\/760080"},{"key":"2","unstructured":"\"Dosimetry for criticality accidents: a manual.\"  196 (1982)"},{"key":"3","doi-asserted-by":"crossref","unstructured":"HJ. 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Holm,  \"Scand J Stat.\"  6, \"A simple sequentially rejective multiple test procedure.\" 65 (1979)"},{"key":"14","doi-asserted-by":"publisher","unstructured":"D Endesfelder, U Oestreicher, U Kulka, et al.  \"Int J Radiat Biol.\"  97, \"RENEB\/EURADOS field exercise 2019: robust dose estimation under outdoor conditions based on the dicentric chromosome assay.\" 1181 (2021)","DOI":"10.1080\/09553002.2021.1941380"},{"key":"15","doi-asserted-by":"crossref","unstructured":"D Endesfelder, U Oestreicher, M Bucher, et al.  \"Radiat Res.\"  199, \"RENEB Inter-Laboratory Comparison 2021: The Dicentric Chromosome Assay.\" 556 (2023)","DOI":"10.1667\/RADE-22-00204.1"},{"key":"28","doi-asserted-by":"crossref","unstructured":"E Gregoire, JF Barquinero, G Gruel, et al.  \"Int J Radiat Biol.\"  97, \"RENEB inter-laboratory comparison 2017: limits and pitfalls of ILCs.\" 888 (2021)","DOI":"10.1080\/09553002.2021.1928782"},{"key":"18","doi-asserted-by":"crossref","unstructured":"U Kulka, L Ainsbury, M Atkinson, et al.  \"Radiat Prot Dosimetry.\"  151, \"Realising the European network of biodosimetry (RENEB).\" 621 (2012)","DOI":"10.1093\/rpd\/ncs157"}],"container-title":["Radiation Research"],"original-title":[],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:59:39Z","timestamp":1791233979000},"score":1,"resource":{"primary":{"URL":"https:\/\/bioone.org\/journals\/radiation-research\/volume-206\/issue-2\/RADE-25-00180.1\/Interlaboratory-Comparison-of-the-Dicentric-Chromosome-Assay-for-a-Mixed\/10.1667\/RADE-25-00180.1.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,27]]},"references-count":30,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,8,1]]}},"URL":"https:\/\/doi.org\/10.1667\/rade-25-00180.1","relation":{},"ISSN":["0033-7587","1938-5404"],"issn-type":[{"value":"0033-7587","type":"print"},{"value":"1938-5404","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,27]]}}}