{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:21:42Z","timestamp":1787023302332,"version":"build-2736575974"},"reference-count":52,"publisher":"Radiation Research Society","issue":"5","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bioone.org\/page\/resources\/researchers\/rights_and_permissions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiation Research"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1667\/rr14686.1","type":"journal-article","created":{"date-parts":[[2017,9,6]],"date-time":"2017-09-06T20:56:50Z","timestamp":1504731410000},"page":"571-584","source":"Crossref","is-referenced-by-count":13,"title":["Radiation Mitigating Properties of Intranasally Administered KL\n                    <sub>4<\/sub>\n                    Surfactant in a Murine Model of Radiation-Induced Lung Damage"],"prefix":"10.1667","volume":"188","author":[{"given":"Melpo","family":"Christofidou-Solomidou","sequence":"first","affiliation":[{"name":"Division of Pulmonary, Allergy, and Critical Care Medicine and the Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, 19104"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph A.","family":"Pietrofesa","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Allergy, and Critical Care Medicine and the Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, 19104"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evguenia","family":"Arguiri","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Allergy, and Critical Care Medicine and the Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, 19104"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantinos","family":"Koumenis","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, 19104"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Segal","sequence":"additional","affiliation":[{"name":"Windtree Therapeutics, Inc., Warrington, Pennsylvania, 18976"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1243","reference":[{"key":"i0033-7587-188-5-491-b04","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.08.058"},{"key":"i0033-7587-188-5-491-b06","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.01306"},{"key":"i0033-7587-188-5-491-b07","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(80)90206-0"},{"key":"i0033-7587-188-5-491-b08","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(83)90420-0"},{"key":"i0033-7587-188-5-491-b09","doi-asserted-by":"publisher","DOI":"10.1016\/0065-2571(94)00020-4"},{"key":"i0033-7587-188-5-491-b10","doi-asserted-by":"publisher","DOI":"10.1378\/chest.111.4.1061"},{"key":"i0033-7587-188-5-491-b11","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(82)90092-X"},{"key":"i0033-7587-188-5-491-b12","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(84)90057-9"},{"key":"i0033-7587-188-5-491-b13","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/141.4_Pt_1.998"},{"key":"i0033-7587-188-5-491-b14","doi-asserted-by":"publisher","DOI":"10.1126\/science.1948032"},{"key":"i0033-7587-188-5-491-b15","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199105010-00010"},{"key":"i0033-7587-188-5-491-b16","doi-asserted-by":"publisher","DOI":"10.1007\/PL00007592"},{"key":"i0033-7587-188-5-491-b17","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199606000-00004"},{"key":"i0033-7587-188-5-491-b18","doi-asserted-by":"publisher","DOI":"10.1007\/PL00007569"},{"key":"i0033-7587-188-5-491-b19","doi-asserted-by":"publisher","DOI":"10.1042\/bj2950019"},{"key":"i0033-7587-188-5-491-b20","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.14.5.8624255"},{"key":"i0033-7587-188-5-491-b21","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e318175dd14"},{"key":"i0033-7587-188-5-491-b22","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21252"},{"key":"i0033-7587-188-5-491-b23","doi-asserted-by":"crossref","unstructured":"Ramstedt U, Serhan CN, Nicolaou KC, Webber SE, Wigzell H, Samuelsson B. Lipoxin A-induced inhibition of human natural killer cell cytotoxicity: studies on stereospecificity of inhibition and mode of action. J Immunol 1987; 138:266\u201370.","DOI":"10.4049\/jimmunol.138.1.266"},{"key":"i0033-7587-188-5-491-b24","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01492-16"},{"key":"i0033-7587-188-5-491-b25","doi-asserted-by":"crossref","unstructured":"Lee JC, Kinniry PA, Arguiri E, Serota M, Kanterakis S, Chatterjee S, et al. Dietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice. Radiat Res 2010; 173, 590\u2013601.","DOI":"10.1667\/RR1522.1"},{"key":"i0033-7587-188-5-491-b26","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.8.1.7092"},{"key":"i0033-7587-188-5-491-b27","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2006.09.013"},{"key":"i0033-7587-188-5-491-b28","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20468"},{"key":"i0033-7587-188-5-491-b29","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-6915(03)00043-7"},{"key":"i0033-7587-188-5-491-b30","doi-asserted-by":"publisher","DOI":"10.2307\/3577364"},{"key":"i0033-7587-188-5-491-b31","doi-asserted-by":"publisher","DOI":"10.2307\/3577363"},{"key":"i0033-7587-188-5-491-b32","doi-asserted-by":"publisher","DOI":"10.1118\/1.2996012"},{"key":"i0033-7587-188-5-491-b33","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2016.76"},{"key":"i0033-7587-188-5-491-b34","doi-asserted-by":"publisher","DOI":"10.4103\/0974-1208.82352"},{"key":"i0033-7587-188-5-491-b35","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00173.2001"},{"key":"i0033-7587-188-5-491-b36","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-13-179"},{"key":"i0033-7587-188-5-491-b37","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-11-269"},{"key":"i0033-7587-188-5-491-b38","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.22.24.8612-8625.2002"},{"key":"i0033-7587-188-5-491-b39","doi-asserted-by":"crossref","unstructured":"Christofidou-Solomidou M, Tyagi S, Pietrofesa R, Dukes F, Arguiri E, Turowski J, et al. Radioprotective role in lung of the flaxseed lignan complex enriched in the phenolic secoisolariciresinol diglucoside (SDG). Radiat Res 2012; 178:568\u201380.","DOI":"10.1667\/RR2980.1"},{"key":"i0033-7587-188-5-491-b40","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00138.2007"},{"key":"i0033-7587-188-5-491-b41","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgv174"},{"key":"i0033-7587-188-5-491-b42","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2009-0210ST"},{"key":"i0033-7587-188-5-491-b43","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(61)90291-0"},{"key":"i0033-7587-188-5-491-b44","doi-asserted-by":"publisher","DOI":"10.1007\/s10517-012-1608-9"},{"key":"i0033-7587-188-5-491-b45","doi-asserted-by":"publisher","DOI":"10.1159\/000066962"},{"key":"i0033-7587-188-5-491-b46","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccc.2010.12.005"},{"key":"i0033-7587-188-5-491-b47","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2014.09.019"},{"key":"i0033-7587-188-5-491-b48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccc.2011.04.001"},{"key":"i0033-7587-188-5-491-b49","doi-asserted-by":"publisher","DOI":"10.1007\/PL00007639"},{"key":"i0033-7587-188-5-491-b50","doi-asserted-by":"publisher","DOI":"10.1089\/jamp.2009.0758"},{"key":"i0033-7587-188-5-491-b51","unstructured":"Wolfson MR, Malone DJ, Wu J, Gregory T, Mazela J, Shaffer TH. Aerosurf(TM) reduces lung inflammation, improves lung mechanics and preserves lung histomorphology in spontaneously breathing CPAP-supported preterm lambs (Poster symposia. Neonatal respiratory). Arch Dis Child 2008; 93(Suppl 2):69."},{"key":"i0033-7587-188-5-491-b52","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2015.11.014"},{"key":"i0033-7587-188-5-491-b53","doi-asserted-by":"publisher","DOI":"10.1097\/HP.0b013e3181a6ee32"},{"key":"i0033-7587-188-5-491-b54","doi-asserted-by":"crossref","unstructured":"DiCarlo AL, Hatchett RJ, Kaminski JM, Ledney GD, Pellmar TC, Okunieff P, et al. Medical countermeasures for radiation combined injury: radiation with burn, blast, trauma and\/or sepsis. Report of an NIAID Workshop, March 26\u201327, 2007. Radiat Res 2008; 169:712\u201321.","DOI":"10.1667\/RR1295.1"},{"key":"i0033-7587-188-5-491-b55","doi-asserted-by":"crossref","unstructured":"Medhora M, Gao F, Wu Q, Molthen RC, Jacobs ER, Moulder JE, et al. Model development and use of ACE inhibitors for preclinical mitigation of radiation-induced injury to multiple organs. Radiat Res 2014; 182:545\u201355.","DOI":"10.1667\/RR13425.1"},{"key":"i0033-7587-188-5-491-b56","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(94)00477-3"}],"container-title":["Radiation Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.bioone.org\/doi\/full-xml\/10.1667\/RR14686.1","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T10:51:55Z","timestamp":1692960715000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.bioone.org\/doi\/10.1667\/RR14686.1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":52,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1667\/RR14686.1"],"URL":"https:\/\/doi.org\/10.1667\/rr14686.1","relation":{},"ISSN":["0033-7587","1938-5404"],"issn-type":[{"value":"0033-7587","type":"print"},{"value":"1938-5404","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11]]}}}