{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T15:05:17Z","timestamp":1767625517438},"reference-count":32,"publisher":"Radiation Research Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiation Research"],"published-print":{"date-parts":[[2020,12,30]]},"DOI":"10.1667\/rr15528.2","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T14:20:33Z","timestamp":1612189233000},"source":"Crossref","is-referenced-by-count":5,"title":["Relative Biological Effectiveness and Non-Poissonian Distribution of Dicentric Chromosome Aberrations following Californium-252 Neutron Exposures of Human Peripheral Blood Lymphocytes"],"prefix":"10.1667","volume":"195","author":[{"given":"Laura C.","family":"Paterson","sequence":"first","affiliation":[{"name":"Canadian Nuclear Laboratories, Chalk River, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre","family":"Yonkeu","sequence":"additional","affiliation":[{"name":"Canadian Nuclear Laboratories, Chalk River, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fawaz","family":"Ali","sequence":"additional","affiliation":[{"name":"Canadian Nuclear Laboratories, Chalk River, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas D.","family":"Priest","sequence":"additional","affiliation":[{"name":"Canadian Nuclear Laboratories, Chalk River, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas R.","family":"Boreham","sequence":"additional","affiliation":[{"name":"McMaster University, Hamilton, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin B.","family":"Seymour","sequence":"additional","affiliation":[{"name":"McMaster University, Hamilton, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farrah","family":"Norton","sequence":"additional","affiliation":[{"name":"Canadian Nuclear Laboratories, Chalk River, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard B.","family":"Richardson","sequence":"additional","affiliation":[{"name":"Canadian Nuclear Laboratories, Chalk River, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1243","reference":[{"key":"9","unstructured":"\"ICRP publication 103. Ann ICRP.\"  37, \"The 2007 Recommendations of the International Commission on Radiological Protection.\" 1 (2007)"},{"key":"2","doi-asserted-by":"crossref","unstructured":"RC Martin, DC Glasgow, MZ Martin,  \"Radioanalytical methods in interdisciplinary research.\"  \"Applications of californium-252 neutron irradiations and other nondestructive examination methods at Oak Ridge National Laboratory.\" 88 (2003)","DOI":"10.1021\/bk-2004-0868.ch007"},{"key":"5","doi-asserted-by":"crossref","unstructured":"\"Ann ICRP.\"  33, \"ICRP Publication 92.\" 1 (2003)","DOI":"10.1016\/S0146-6453(03)00024-1"},{"key":"10","unstructured":"EJ Hall  and HH Rossi  \"Californium-252 in teaching and research.\"  (1974)"},{"key":"15","unstructured":"\"Model REM 500.\""},{"key":"17","doi-asserted-by":"crossref","unstructured":"RJ McConn, CJ Gesh, RT Pagh, et al.  \"Compendium of material composition data for radiation transport modeling revision 1 (PIET-43741-TM-963, PNNL-15870 Rev. 1).\"  (2011)","DOI":"10.2172\/1023125"},{"key":"18","unstructured":"\"Reference neutron radiations Part 1: Characteristics and methods of production. ISO 8529-1).\"  (2000)"},{"key":"20","unstructured":"c2018"},{"key":"21","unstructured":"\"Blood, whole (ICRU-44).\""},{"key":"23","unstructured":"\"Reference neutron radiations Part 3: Calibration of area and personal dosimeters and determination of their response as a function of neutron energy and angle of incidence. ISO 8529-3.\"  (2001)"},{"key":"24","doi-asserted-by":"crossref","unstructured":"M Szluinska, AA Edwards, DC Lloyd,  \"Chromosomal alterations.\"  \"Statistical methods for biological dosimetry.\" 351 (2007)","DOI":"10.1007\/978-3-540-71414-9_23"},{"key":"6","doi-asserted-by":"crossref","unstructured":"E Schmid, D Schlegel, S Guldbakke, et al.  \"Radiat Environ Biophys.\"  42, \"RBE of nearly monoenergetic neutrons at energies of 36 keV\u201314.6 MeV for induction of dicentrics in human lymphocytes.\" 87 (2003)","DOI":"10.1007\/s00411-003-0200-0"},{"key":"22","doi-asserted-by":"crossref","unstructured":"EA Ainsbury  and DC Lloyd  \"Health Phys.\"  98, \"Dose estimation software for radiation biodosimetry.\" 290 (2010)","DOI":"10.1097\/01.HP.0000346305.84577.b4"},{"key":"1","doi-asserted-by":"crossref","unstructured":"RC Martin, JB Knauer, PA Balo,  \"Appl Radiat Isot.\"  53, \"Production, distribution and applications of californium-252 neutron sources.\" 785 (2000)","DOI":"10.1016\/S0969-8043(00)00214-1"},{"key":"3","doi-asserted-by":"crossref","unstructured":"F Ali, J Atanackovic, C Boyer, et al.  \"J Radiol Prot.\"  38, \"Dosimetric and microdosimetric analyses for blood exposed to reactor-derived thermal neutrons.\" 1037 (2018)","DOI":"10.1088\/1361-6498\/aaca9f"},{"key":"7","doi-asserted-by":"crossref","unstructured":"DC Lloyd, RJ Purrott, EJ Reeder, et al.  \"Int J Radiat Biol Relat Stud Phys Chem Med.\"  34, \"Chromosome aberrations induced in human lymphocytes by radiation from 252Cf.\" 177 (1978)","DOI":"10.1080\/09553007814550751"},{"key":"8","doi-asserted-by":"crossref","unstructured":"K Tanaka, N Gajendiran, N Kamada,  \"Indian J Sci Technol.\"  2, \"Relative biological effectiveness (RBE) and dose rate dependent ratio of translocation to dicentric chromosome yield in 252Cf neutrons.\" 1 (2009)","DOI":"10.17485\/ijst\/2009\/v2i1.1"},{"key":"11","doi-asserted-by":"crossref","unstructured":"RP Virsik  and D Harder  \"Radiat Res.\"  85, \"Statistical interpretation of the overdispersed distribution of radiation-induced dicentric chromosome aberrations at high LET.\" 13 (1981)","DOI":"10.2307\/3575434"},{"key":"12","doi-asserted-by":"crossref","unstructured":"FN Flegal, Y Devantier, JP McNamee, et al.  \"Health Phys.\"  98, \"QuickScan dicentric chromosome analysis for radiation biodosimetry.\" 276 (2012)","DOI":"10.1097\/HP.0b013e3181aba9c7"},{"key":"13","doi-asserted-by":"crossref","unstructured":"FN Flegal, Y Devantier, L Marro, et al.  \"Health Phys.\"  102, \"Validation of Quickscan dicentric chromosome analysis for high throughput radiation biological dosimetry.\" 143 (2012)","DOI":"10.1097\/HP.0b013e3182307758"},{"key":"14","doi-asserted-by":"crossref","unstructured":"E Schmid, FM Wagner, L Canella, et al.  \"Radiat Environ Biophys.\"  52, \"RBE of thermal neutrons for induction of chromosome aberrations in human lymphocytes.\" 113 (2013)","DOI":"10.1007\/s00411-012-0449-2"},{"key":"16","doi-asserted-by":"crossref","unstructured":"T Sato, Y Iwamoto, S Hashimoto, et al.  \"J Nucl Sci Technol.\"  55, \"Features of Particle and Heavy Ion Transport code System (PHITS) current version 3.02.\" 684 (2018)","DOI":"10.1080\/00223131.2017.1419890"},{"key":"19","doi-asserted-by":"crossref","unstructured":"J Atanackovic, A Yonkeu, J Dubeau, et al.  \"Appl Radiat Isot.\"  99, \"Characterization of neutron fields from bare and heavy water moderated 252Cf spontaneous fission source using Bonner sphere spectrometer.\" 122 (2015)","DOI":"10.1016\/j.apradiso.2015.02.023"},{"key":"25","doi-asserted-by":"crossref","unstructured":"E Schmid, H Schraube, M Bauchinger,  \"Int J Radiat Biol.\"  73, \"Chromosome aberration frequencies in human lymphocytes irradiated in a phantom by a mixed beam of fission neutrons and gamma-rays.\" 263 (1998)","DOI":"10.1080\/095530098142356"},{"key":"26","doi-asserted-by":"crossref","unstructured":"DC Lloyd, RJ Purrott, GW Dolphin, et al.  \"Int J Radiat Biol Relat Stud Phys Chem Med.\"  29, \"Chromosome aberrations induced in human lymphocytes by neutron irradiation.\" 169 (1976)","DOI":"10.1080\/09553007614550181"},{"key":"27","doi-asserted-by":"crossref","unstructured":"E Schmid, D Regulla, S Guldbakke, et al.  \"Radiat Res.\"  154, \"The effectiveness of monoenergetic neutrons at 565 keV in producing dicentric chromosomes in human lymphocytes at low doses.\" 307 (2000)","DOI":"10.1667\/0033-7587(2000)154[0307:TEOMNA]2.0.CO;2"},{"key":"28","doi-asserted-by":"crossref","unstructured":"E Schmid, D Regulla, S Guldbakke, et al.  \"Radiat Res.\"  157, \"Relative biological effectiveness of 144 keV neutrons in producing dicentric chromosomes in human lymphocytes compared with 60Co gamma rays under head-to-head conditions.\" 453 (2002)","DOI":"10.1667\/0033-7587(2002)157[0453:RBEOKN]2.0.CO;2"},{"key":"29","doi-asserted-by":"crossref","unstructured":"M Bauchinger, L Koester, E Schmid, et al.  \"Int J Radiat Biol Relat Stud Phys Chem Med.\"  45, \"Chromosome aberrations in human lymphocytes induced by fission neutrons.\" 449 (1984)","DOI":"10.1080\/09553008414550651"},{"key":"30","doi-asserted-by":"crossref","unstructured":"L Fabry, A Leonard, A Wambersie,  \"Radiat Res.\"  103, \"Induction of chromosome aberrations in G0 human lymphocytes by low doses of ionizing radiations of different quality.\" 122 (1985)","DOI":"10.2307\/3576677"},{"key":"31","doi-asserted-by":"crossref","unstructured":"M Bauchinger, E Schmid, G Rimpl, et al.  \"Mutat Res.\"  27, \"Chromosome aberrations in human lymphocytes after irradiation with 15.0-MeV neutrons in vitro. I. Dose-response relation and RBE.\" 103 (1975)","DOI":"10.1016\/0027-5107(75)90277-8"},{"key":"32","doi-asserted-by":"crossref","unstructured":"R Nolte, KH Muhlbradt, JP Meulders, et al.  \"Radiat Environ Biophys.\"  44, \"RBE of quasi-monoenergetic 60 MeV neutron radiation for induction of dicentric chromosomes in human lymphocytes.\" 201 (2005)","DOI":"10.1007\/s00411-005-0021-4"},{"key":"4","unstructured":"\"Cytogenetic Dosimetry: Applications in Preparedness for and Response to Radiation Emergencies.\"  (2011)"}],"container-title":["Radiation Research"],"original-title":[],"deposited":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T10:45:52Z","timestamp":1659609952000},"score":1,"resource":{"primary":{"URL":"https:\/\/bioone.org\/journals\/radiation-research\/volume-195\/issue-2\/RR15528.2\/Relative-Biological-Effectiveness-and-Non-Poissonian-Distribution-of-Dicentric-Chromosome\/10.1667\/RR15528.2.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,30]]},"references-count":32,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,2,1]]}},"URL":"https:\/\/doi.org\/10.1667\/rr15528.2","relation":{},"ISSN":["0033-7587"],"issn-type":[{"value":"0033-7587","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12,30]]}}}