{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T10:12:17Z","timestamp":1773742337098,"version":"3.50.1"},"reference-count":23,"publisher":"Radiation Research Society","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiation Research"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1667\/rr2699.1","type":"journal-article","created":{"date-parts":[[2011,12,21]],"date-time":"2011-12-21T21:45:41Z","timestamp":1324503941000},"page":"109-116","source":"Crossref","is-referenced-by-count":28,"title":["Effect of Low and Chronic Radiation Exposure: A Case-Control Study of Mental Retardation and Cleft Lip\/Palate in the Monazite-Bearing Coastal Areas of Southern Kerala"],"prefix":"10.1667","volume":"177","author":[{"given":"P. K. M.","family":"Koya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. P.","family":"Chougaonkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Predeep","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. J.","family":"Jojo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. D.","family":"Cheriyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y. S.","family":"Mayya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Seshadri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1243","reference":[{"key":"i0033-7587-177-1-109-b04","unstructured":"Rose KSB. Review of health studies in Kerala. Nucl Energy 1982; 21:399\u2013408."},{"key":"i0033-7587-177-1-109-b05","doi-asserted-by":"crossref","unstructured":"Mistry KB, Bhathran KG, Ayengar ARG. Radioactivity in the diet of population of Kerala coast including monazite bearing high radiation areas. Health Phys 1970; 19:535\u201342.","DOI":"10.1097\/00004032-197010000-00008"},{"key":"i0033-7587-177-1-109-b06","unstructured":"Gopal-Ayengar AR, Nayar GG, George KP, Mistry KB. Biological effects of high background radioactivity \u2013 studies on plants growing on the monazite-bearing areas of Kerala coast and adjoining regions. Ind J Exp Biol 1970; 8:313\u20138."},{"key":"i0033-7587-177-1-109-b07","doi-asserted-by":"crossref","unstructured":"Nayar GG, George KP Ayengar ARG. On the biological effects of high background radioactivity: Studies on Tradescantia grown in radioactive monazite sand. Radiat Bot 1970; 10:287\u201392.","DOI":"10.1016\/S0033-7560(70)80023-0"},{"key":"i0033-7587-177-1-109-b08","doi-asserted-by":"crossref","unstructured":"Nayar GG, George KP, Ayengar ARG. The relationship between cytological abnormalities and interphase chromosome volume in plants growing in the high background radiation areas. Radiat Bot 1971; 11:175\u20136.","DOI":"10.1016\/S0033-7560(71)90713-7"},{"key":"i0033-7587-177-1-109-b09","doi-asserted-by":"crossref","unstructured":"Gruneberg H. Genetical research in an area of high natural radioactivity in South India. Nature 1964; 204:222\u20134.","DOI":"10.1038\/204222a0"},{"key":"i0033-7587-177-1-109-b11","doi-asserted-by":"crossref","unstructured":"Chougaonkar MP, Eappen KP, Ramachandran TV, Shetty PG, Mayya YS, Sadasivan S, et al. Profiles of doses to the population living in the high background radiation areas in Kerala, India. J Environ Radioact 2004; 71:275\u201397.","DOI":"10.1016\/S0265-931X(03)00174-7"},{"key":"i0033-7587-177-1-109-b13","doi-asserted-by":"crossref","unstructured":"Kochupillai N, Verma IC, Grewal MS, Ramalingaswamy V. Down syndrome and related abnormalities in an area of high background radiation in coastal Kerala. Nature 1976; 262:60\u201361.","DOI":"10.1038\/262060a0"},{"key":"i0033-7587-177-1-109-b14","doi-asserted-by":"crossref","unstructured":"Jaikrishan G, Andrews VJ, Thampi MV, Koya PKM, Chauhan PS. Genetic monitoring of the human population from high level natural radiation areas of Kerala on the southwest coast of India. I. Prevalence of congenital malformations in newborns. Radiat Res 1999; 152 (Suppl):S149\u201353.","DOI":"10.2307\/3580135"},{"key":"i0033-7587-177-1-109-b15","doi-asserted-by":"crossref","unstructured":"Cheriyan VD, Kurien CJ, Das B, Ramachandran EN, Karuppasamy CV, Thampi MV, et al. Genetic monitoring of the human population from high level natural radiation areas of Kerala on the southwest coast of India. II. Incidence of numerical and structural chromosomal aberrations in the lymphocytes of newborns. Radiat Res 1999; 152 (Suppl):S154\u20138.","DOI":"10.2307\/3580136"},{"key":"i0033-7587-177-1-109-b16","doi-asserted-by":"crossref","unstructured":"Thampi MV, Cheriyan VD, Kurien CJ, Ramachandran EN, Karuppasamy CV, Koya PKM, et al. Cytogenetic studies in the high level natural radiation areas of Kerala. Int Congress Ser 2002; 1225:207\u201311.","DOI":"10.1016\/S0531-5131(01)00511-8"},{"key":"i0033-7587-177-1-109-b17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ics.2004.11.152"},{"key":"i0033-7587-177-1-109-b19","doi-asserted-by":"publisher","DOI":"10.1097\/01.HP.0000327646.54923.11"},{"key":"i0033-7587-177-1-109-b20","doi-asserted-by":"crossref","unstructured":"Binu VS, Gangadharan P, Jayalekshmi P, Nair RRK, Nair MK, Rajan B, et al. The risk of lung cancer in HBR area in India \u2013 a case control study. Int Congress Ser 2005; 1276:236\u20137.","DOI":"10.1016\/j.ics.2004.11.156"},{"key":"i0033-7587-177-1-109-b21","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.202400499"},{"key":"i0033-7587-177-1-109-b23","doi-asserted-by":"crossref","unstructured":"Wyszynski DF, Beaty TH, Maestri NE. Genetics of nonsyndromic oral clefts revisited. Cleft Palate Craniofac J 1996; 33:406\u201317.","DOI":"10.1597\/1545-1569(1996)033<0406:GONOCR>2.3.CO;2"},{"key":"i0033-7587-177-1-109-b24","doi-asserted-by":"crossref","unstructured":"Chougaonkar MP, Shetty PG, Mayya YS, Puranik VD, Kushwaha HS. Performance characteristics of newly modified CaSO4:Dy based indigenous thermoluminescent dosimeters for environmental radiation monitoring. J Nucl Sci Technol 2008; Suppl 5:610\u201313.","DOI":"10.1080\/00223131.2008.10875929"},{"key":"i0033-7587-177-1-109-b25","doi-asserted-by":"crossref","unstructured":"1990 recommendations of the International Commission on Radiological Protection. 1991; Ann ICRP; 21(1\u20133).","DOI":"10.1016\/0146-6453(91)90067-Q"},{"key":"i0033-7587-177-1-109-b28","unstructured":"Cornfield J. A method of estimating comparative rates from clinical data: application to cancer of the lung, breast and cervix. J Natl Cancer Inst 1951; 11:1269\u201375."},{"key":"i0033-7587-177-1-109-b30","doi-asserted-by":"crossref","unstructured":"Otake M, Schull WJ. In utero exposure to A-bomb radiation and mental retardation: a reassessment. Br J Radiol 1984; 57:409\u201314.","DOI":"10.1259\/0007-1285-57-677-409"},{"key":"i0033-7587-177-1-109-b31","doi-asserted-by":"crossref","unstructured":"Otake M, Schull WJ. Radiation-related brain damage and growth retardation among prenatally exposed atomic bomb survivors. Int J Radiat Biol 1998; 74:159\u201371.","DOI":"10.1080\/095530098141555"},{"key":"i0033-7587-177-1-109-b32","doi-asserted-by":"crossref","unstructured":"Nowakowski RS, Hayes LN. Radiation, retardation and the developing brain: time is the crucial variable. Acta Paediatr 2008; 97:527\u201331.","DOI":"10.1111\/j.1651-2227.2008.00764.x"},{"key":"i0033-7587-177-1-109-b37","doi-asserted-by":"crossref","unstructured":"Dolk H. Epidemiologic approaches to identifying environmental causes of birth defects. Am J Med Genet C Semin Med Genet 2004; 125C:4\u201311.","DOI":"10.1002\/ajmg.c.30000"}],"container-title":["Radiation Research"],"original-title":[],"language":"en","deposited":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T05:43:46Z","timestamp":1561095826000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.bioone.org\/doi\/10.1667\/RR2699.1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1667\/RR2699.1"],"URL":"https:\/\/doi.org\/10.1667\/rr2699.1","relation":{},"ISSN":["0033-7587","1938-5404"],"issn-type":[{"value":"0033-7587","type":"print"},{"value":"1938-5404","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}