{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T09:17:10Z","timestamp":1783675030015,"version":"3.55.0"},"reference-count":0,"publisher":"Bioscientifica","issue":"1","content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1963,12,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>The pituitary stalk was divided in a series of rhesus monkeys. The animals were allowed to survive up to 12 months, and an attempt was made to correlate structural and functional changes in the pituitary with the pattern of water metabolism after operation.<\/jats:p>\n                  <jats:p>It was found that if the cut ends of the stalk were separated by an impermeable barrier, the animals did not develop the classical signs of diabetes insipidus, despite the fact that the infundibular process atrophied below the lesion. If, however, the cut ends of the stalk were allowed to re-unite, the three classical phases of diabetes insipidus were usually apparent, but the 'permanent' polyuria diminished with time.<\/jats:p>\n                  <jats:p>Separation of the cut ends of the stalk by a barrier was associated with signs of hypofunction of the pars distalis, and it is suggested that such hypofunction nullifies the effect of the neurohypophysial lesion on the development of polyuria.<\/jats:p>","DOI":"10.1677\/joe.0.0280107","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T16:43:33Z","timestamp":1229013813000},"page":"107-118","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-5","source":"Crossref","is-referenced-by-count":1,"title":["THE PITUITARY STALK AND WATER METABOLISM IN THE MONKEY"],"prefix":"10.1530","volume":"28","author":[{"given":"R. L.","family":"HOLMES","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/28\/1\/joe_28_1_014.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/28\/1\/107\/52284\/joe_28_1_014.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/28\/1\/107\/52284\/joe_28_1_014.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T08:45:41Z","timestamp":1783673141000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article\/28\/1\/107\/7714\/THE-PITUITARY-STALK-AND-WATER-METABOLISM-IN-THE"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1963,12,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1963,12,1]]}},"URL":"https:\/\/doi.org\/10.1677\/joe.0.0280107","relation":{},"ISSN":["1479-6805","0022-0795"],"issn-type":[{"value":"1479-6805","type":"electronic"},{"value":"0022-0795","type":"print"}],"subject":[],"published":{"date-parts":[[1963,12,1]]}}}