{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T09:16:38Z","timestamp":1783674998205,"version":"3.55.0"},"reference-count":0,"publisher":"Bioscientifica","issue":"2","content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1964,1,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>The effect of a gestagen (lynoestrenol) on anaphylactic reactions was investigated in rats and the effect of intracutaneous and intravenous re-injection of horse serum used as antigen was examined.<\/jats:p>\n                  <jats:p>Gestagen treatment intensified the cutaneous reaction, decreased the rectal temperature and caused death in 50 % of the animals. In control rats the intravenous re-injection of the antigen only caused a slight decrease in rectal temperature without killing any of them.<\/jats:p>\n                  <jats:p>It is suggested that the markedly increased sensitivity of rats, a species normally resistant to anaphylactic reactions, may be due to the inhibitory effect of the administered gestagen on pituitary gonadotrophin secretion.<\/jats:p>","DOI":"10.1677\/joe.0.0280159","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T16:43:33Z","timestamp":1229013813000},"page":"159-161","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-5","source":"Crossref","is-referenced-by-count":1,"title":["THE EFFECT OF ORALLY ADMINISTERED GESTAGEN ON THE ANAPHYLACTIC REACTIONS IN RATS"],"prefix":"10.1530","volume":"28","author":[{"given":"F. E.","family":"SZONT\u00c1GH","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"VARGA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1.","family":"BARD\u00d3CZY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"F\u00d6LDI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/28\/2\/joe_28_2_005.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/28\/2\/159\/52376\/joe_28_2_005.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/28\/2\/159\/52376\/joe_28_2_005.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T08:47:18Z","timestamp":1783673238000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article\/28\/2\/159\/7749\/THE-EFFECT-OF-ORALLY-ADMINISTERED-GESTAGEN-ON-THE"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1964,1,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1964,1,1]]}},"URL":"https:\/\/doi.org\/10.1677\/joe.0.0280159","relation":{},"ISSN":["1479-6805","0022-0795"],"issn-type":[{"value":"1479-6805","type":"electronic"},{"value":"0022-0795","type":"print"}],"subject":[],"published":{"date-parts":[[1964,1,1]]}}}