{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T09:21:36Z","timestamp":1783675296229,"version":"3.55.0"},"reference-count":0,"publisher":"Bioscientifica","issue":"3","content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1966,7,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>Serum tyrosine was measured in 22 normal subjects, 17 patients with non-toxic goitre, ten patients with hypothyroidism, 37 patients with thyrotoxicosis and eight geriatric patients. Low values were obtained in hypothyroidism and high values in thyrotoxicosis. In thyrotoxicosis there was only a small overlap with the euthyroid subjects. Thus, measurements of serum tyrosine appear to be a useful test for the diagnosis of hyperthyroidism, not invalidated by previous iodine administration and not involving the use of radio-isotopes. Administration of vitamin C reduced the increased values of tyrosine in thyrotoxicosis to normal levels. It is suggested that a latent vitamin C deficiency may partly explain the increase in the serum tyrosine values in thyrotoxicosis.<\/jats:p>","DOI":"10.1677\/joe.0.0350223","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T16:50:14Z","timestamp":1229014214000},"page":"223-228","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-5","source":"Crossref","is-referenced-by-count":11,"title":["THE SERUM TYROSINE LEVEL AS AN INDEX OF THYROID FUNCTION"],"prefix":"10.1530","volume":"35","author":[{"given":"B.","family":"MALAMOS","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. J.","family":"MIRAS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. N.","family":"KARLI-SAMOUILIDOU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. A.","family":"KOUTRAS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/35\/3\/joe_35_3_002.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/35\/3\/223\/53690\/joe_35_3_002.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/35\/3\/223\/53690\/joe_35_3_002.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T09:06:29Z","timestamp":1783674389000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article\/35\/3\/223\/8180\/THE-SERUM-TYROSINE-LEVEL-AS-AN-INDEX-OF-THYROID"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1966,7,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1966,7,1]]}},"URL":"https:\/\/doi.org\/10.1677\/joe.0.0350223","relation":{},"ISSN":["1479-6805","0022-0795"],"issn-type":[{"value":"1479-6805","type":"electronic"},{"value":"0022-0795","type":"print"}],"subject":[],"published":{"date-parts":[[1966,7,1]]}}}