{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T09:21:34Z","timestamp":1783675294449,"version":"3.55.0"},"reference-count":0,"publisher":"Bioscientifica","issue":"3","content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1966,7,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>3\u03b1-, 3\u03b2-, 11\u03b2-, 16\u03b2-, 17\u03b2- and 20\u03b2-hydroxysteroid dehydrogenases have been localized histochemically in the Leydig cells of prepubertal and adult human testes; 3\u03b1-, 16\u03b2- and 17\u03b2-hydroxysteroid dehydrogenases were present in the seminiferous tubules also. A similar pattern was found in cryptorchid testes. In addition 3\u03b2-sulphoxy steroids, including DHA sulphate, gave a good colour reaction in human Leydig cells. Testes from oestrogen-treated subjects had no histochemically demonstrable hydroxysteroid dehydrogenases and this applied also to infarcted testes. Testes from a case of Klinefelter's syndrome were found to lack 17\u03b2- and 20\u03b2-hydroxysteroid dehydrogenases in the Leydig cells. The biochemical significance of these results is discussed.<\/jats:p>","DOI":"10.1677\/joe.0.0350239","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T16:50:14Z","timestamp":1229014214000},"page":"239-NP","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-5","source":"Crossref","is-referenced-by-count":24,"title":["HYDROXYSTEROID DEHYDROGENASES IN NORMAL AND ABNORMAL HUMAN TESTES"],"prefix":"10.1530","volume":"35","author":[{"given":"A. H.","family":"BAILLIE","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. S.","family":"MACK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/35\/3\/joe_35_3_004.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/35\/3\/239\/53751\/joe_35_3_004.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/35\/3\/239\/53751\/joe_35_3_004.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T09:07:36Z","timestamp":1783674456000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article\/35\/3\/239\/8204\/HYDROXYSTEROID-DEHYDROGENASES-IN-NORMAL-AND"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1966,7,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1966,7,1]]}},"URL":"https:\/\/doi.org\/10.1677\/joe.0.0350239","relation":{},"ISSN":["1479-6805","0022-0795"],"issn-type":[{"value":"1479-6805","type":"electronic"},{"value":"0022-0795","type":"print"}],"subject":[],"published":{"date-parts":[[1966,7,1]]}}}