{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T09:21:09Z","timestamp":1783675269722,"version":"3.55.0"},"reference-count":0,"publisher":"Bioscientifica","issue":"3","content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1967,3,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>The pituitary glands of 11 rats (six females and five males, weighing 140\u2013200g.) with hereditary hypothalamic diabetes insipidus (DI) were found to contain oxytocin but no vasopressin.<\/jats:p>\n                  <jats:p>The DI rats could not always be distinguished from rats without diabetes insipidus (non-diabetes insipidus, NDI rats) by measurement of their daily urine volume.<\/jats:p>\n                  <jats:p>Stimulation of the neurohypophysis by fall in arterial pressure (haemorrhage, methacholine) or by nicotine, released vasopressin in NDI rats to produce a sustained antidiuresis, but in the DI rats there was only a transient fall in urine flow which did not outlast the hypotension.<\/jats:p>\n                  <jats:p>The DI rats were about twice as sensitive to vasopressin as NDI rats. As assay preparations they have the advantage that they cannot respond to vasopressin-releasing stimuli.<\/jats:p>\n                  <jats:p>Prolonged administration of Pitressin tannate in oil increased maximum urinary osmolality in DI rats, but failed to increase their sensitivity to intravenously injected vasopressin.<\/jats:p>","DOI":"10.1677\/joe.0.0370335","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T16:50:14Z","timestamp":1229014214000},"page":"335-344","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-5","source":"Crossref","is-referenced-by-count":13,"title":["THE VALUE OF RATS WITH HEREDITARY HYPOTHALAMIC DIABETES INSIPIDUS FOR THE BIOASSAY OF VASOPRESSIN"],"prefix":"10.1530","volume":"37","author":[{"given":"J. J.","family":"JONES","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"LEE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/37\/3\/joe_37_3_011.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/37\/3\/335\/54105\/joe_37_3_011.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/37\/3\/335\/54105\/joe_37_3_011.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T09:12:12Z","timestamp":1783674732000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article\/37\/3\/335\/8311\/THE-VALUE-OF-RATS-WITH-HEREDITARY-HYPOTHALAMIC"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1967,3,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1967,3,1]]}},"URL":"https:\/\/doi.org\/10.1677\/joe.0.0370335","relation":{},"ISSN":["1479-6805","0022-0795"],"issn-type":[{"value":"1479-6805","type":"electronic"},{"value":"0022-0795","type":"print"}],"subject":[],"published":{"date-parts":[[1967,3,1]]}}}