{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T13:12:52Z","timestamp":1783602772622,"version":"3.55.0"},"reference-count":0,"publisher":"Bioscientifica","issue":"1","content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1970,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>SUMMARY<\/jats:title>\n                    <jats:p>The use of the resting plasma cortisol level, the diurnal plasma cortisol rhythm and plasma cortisol response to a maximal adrenocorticotrophic hormone (ACTH) infusion or insulin-induced hypoglycaemia as indirect tests of hypothalamo\u2014pituitary\u2014adrenocortical function was examined in a group of 27 patients with pituitary disease. While the first three tests provided similar information about hypothalamo\u2014pituitary\u2014adrenocortical function, the plasma cortisol response to insulin-induced hypoglycaemia did not provide further clinically useful information. Difficulties in interpretation of dynamic tests of hypothalamo\u2014pituitary\u2014adrenocortical function are discussed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1677\/joe.0.0480047","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T16:50:14Z","timestamp":1229014214000},"page":"47-54","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-5","source":"Crossref","is-referenced-by-count":4,"title":["COMPARISON OF TESTS OF HYPOTHALAMO-PITUITARY-ADRENOCORTICAL FUNCTION IN PITUITARY DISEASE"],"prefix":"10.1530","volume":"48","author":[{"given":"J. W. H.","family":"DOAR","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"WYNN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. J.","family":"WEBB","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/48\/1\/joe_48_1_005.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/48\/1\/47\/57008\/joe_48_1_005.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/48\/1\/47\/57008\/joe_48_1_005.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T12:12:56Z","timestamp":1783599176000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article\/48\/1\/47\/9260\/COMPARISON-OF-TESTS-OF-HYPOTHALAMO-PITUITARY"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,9,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1970,9,1]]}},"URL":"https:\/\/doi.org\/10.1677\/joe.0.0480047","relation":{},"ISSN":["1479-6805","0022-0795"],"issn-type":[{"value":"1479-6805","type":"electronic"},{"value":"0022-0795","type":"print"}],"subject":[],"published":{"date-parts":[[1970,9,1]]}}}