{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T12:21:09Z","timestamp":1783599669974,"version":"3.55.0"},"reference-count":0,"publisher":"Bioscientifica","issue":"3","content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1974,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Thyrotrophin releasing hormone (TRH) is a potent stimulus of the release of thyrotrophin (TSH) and prolactin from the anterior pituitary gland of man (Bowers, Friesen, Hwang, Guyda &amp; Folkers, 1971; Jacobs, Snyder, Wilber, Utiger &amp; Daughaday, 1971; L'Hermite, Vanhaelst, Copinschi, Leclercq, Golstein, Bruno &amp; Robyn, 1972; Toft, Boyns, Cole, Groom, Hunter &amp; Irvine, 1973). Whereas the plasma TSH response to intravenous TRH is enhanced in patients with primary hypothyroidism, and abolished in patients with thyrotoxicosis, the relationship between thyroid status and prolactin release by TRH is not clear. Although there is a small increase in plasma prolactin in hypothyroidism (Jacobs et al. 1971; Toft et al. 1973) the response to TRH is not significantly different from that seen in normal subjects (Toft et al. 1973). Recently, Snyder, Jacobs, Utiger &amp; Daughaday (1973) found that when patients with thyroid disease were studied before and after treatment, the prolactin response to TRH<\/jats:p>","DOI":"10.1677\/joe.0.0610515","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T17:08:26Z","timestamp":1229015306000},"page":"515-516","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-5","source":"Crossref","is-referenced-by-count":5,"title":["PROLACTIN RESPONSE TO THYROTROPHIN RELEASING HORMONE IN THYROTOXICOSIS"],"prefix":"10.1530","volume":"61","author":[{"given":"A. D.","family":"TOFT","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. R.","family":"BOYNS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. N.","family":"COLE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. J.","family":"IRVINE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/61\/3\/joe_61_3_021.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/61\/3\/515\/60359\/joe_61_3_021.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/61\/3\/515\/60359\/joe_61_3_021.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T11:37:26Z","timestamp":1783597046000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article\/61\/3\/515\/10396\/PROLACTIN-RESPONSE-TO-THYROTROPHIN-RELEASING"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,6,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1974,6,1]]}},"URL":"https:\/\/doi.org\/10.1677\/joe.0.0610515","relation":{},"ISSN":["1479-6805","0022-0795"],"issn-type":[{"value":"1479-6805","type":"electronic"},{"value":"0022-0795","type":"print"}],"subject":[],"published":{"date-parts":[[1974,6,1]]}}}