{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T12:22:38Z","timestamp":1783599758854,"version":"3.55.0"},"reference-count":0,"publisher":"Bioscientifica","issue":"2","content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1974,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>*Department of Biochemistry, \u2020Department of Obstetrics and Gynaecology, Program in Reproductive Biology and \u2021Department of Pathology, McMaster University, Health Sciences Centre, Hamilton, Ontario, Canada L8S 4J9<\/jats:p>\n                  <jats:p>(Received 28 May 1974)<\/jats:p>\n                  <jats:p>Although (\u2212)-trans-\u03949-tetrahydrocannabinol (THC), the major psychoactive constituent of marihuana (Mechoulam &amp; Shani, 1970), has a wide variety of pharmacological actions, little is known about the effects of this compound on endocrine function. Nir, Ayalon, Tsafriri, Cordova &amp; Lindner (1973) demonstrated that administration of THC to pro-oestrous rats resulted in suppression of the pre-ovulatory surge of luteinizing hormone. Kolodny, Masters, Kolodner &amp; Toro (1974) have found depressed plasma testosterone levels in marihuana smokers. Gynaecomastia in chronic marihuana smokers has been reported (Harmon &amp; Aliapoulos, 1972) and intimated to result from an effect of THC on prolactin (PRL) secretion. Since oestradiol-17\u03b2 benzoate (OB) is known to affect PRL release (Chen &amp; Meites, 1970), the present work was undertaken to examine the hypothesis<\/jats:p>","DOI":"10.1677\/joe.0.0630415","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T17:08:26Z","timestamp":1229015306000},"page":"415-416","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-5","source":"Crossref","is-referenced-by-count":12,"title":["INCREASE OF SERUM PROLACTIN IN MALE RATS BY (\u2212)-\n                    <i>TRANS<\/i>\n                    -\u03949-TETRAHYDROCANNABINOL"],"prefix":"10.1530","volume":"63","author":[{"given":"J. D.","family":"DALEY","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. A.","family":"BRANDA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"ROSENFELD","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. V.","family":"YOUNGLAI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/63\/2\/joe_63_2_020.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/63\/2\/415\/60473\/joe_63_2_020.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/63\/2\/415\/60473\/joe_63_2_020.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T11:39:18Z","timestamp":1783597158000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article\/63\/2\/415\/10443\/INCREASE-OF-SERUM-PROLACTIN-IN-MALE-RATS-BY-TRANS"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,11,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1974,11,1]]}},"URL":"https:\/\/doi.org\/10.1677\/joe.0.0630415","relation":{},"ISSN":["1479-6805","0022-0795"],"issn-type":[{"value":"1479-6805","type":"electronic"},{"value":"0022-0795","type":"print"}],"subject":[],"published":{"date-parts":[[1974,11,1]]}}}