{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T15:17:54Z","timestamp":1783610274328,"version":"3.55.0"},"reference-count":0,"publisher":"Bioscientifica","issue":"2","content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1976,8,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>Basal gonadotrophin and sex steroid levels and responses to an intravenous injection of 100 \u03bcg gonadotrophin releasing hormone (Gn-RH) have been studied in 15 patients with polycystic ovaries. Mean basal LH concentration was raised and an excessive, exaggerated and prolonged response was observed after Gn-RH treatment, but patients could further be subdivided into two functional groups on the basis of their basal LH values and LH response patterns. Evidence was also produced which suggested a breakdown in the negative feedback mechanism in these patients.<\/jats:p>","DOI":"10.1677\/joe.0.0700163","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T17:22:29Z","timestamp":1229016149000},"page":"163-171","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-5","source":"Crossref","is-referenced-by-count":16,"title":["ABNORMAL LUTEINIZING HORMONE RESPONSE PATTERNS TO SYNTHETIC GONADOTROPHIN RELEASING HORMONE IN PATIENTS WITH POLYCYSTIC OVARIAN SYNDROME"],"prefix":"10.1530","volume":"70","author":[{"given":"M.","family":"KATZ","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. J.","family":"CARR","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/70\/2\/joe_70_2_001.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/70\/2\/163\/131976\/joe_70_2_001.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/70\/2\/163\/131976\/joe_70_2_001.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T14:53:50Z","timestamp":1783608830000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article\/70\/2\/163\/23266\/ABNORMAL-LUTEINIZING-HORMONE-RESPONSE-PATTERNS-TO"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,8,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1976,8,1]]}},"URL":"https:\/\/doi.org\/10.1677\/joe.0.0700163","relation":{},"ISSN":["1479-6805","0022-0795"],"issn-type":[{"value":"1479-6805","type":"electronic"},{"value":"0022-0795","type":"print"}],"subject":[],"published":{"date-parts":[[1976,8,1]]}}}