{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T23:30:55Z","timestamp":1790983855683,"version":"4.1.0"},"reference-count":0,"publisher":"Bioscientifica","issue":"2","content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1977,5,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>Changes in the concentrations of ovarian steroids and pituitary gonadotrophins were measured by radioimmunoassay in the jugular plasma of six Clun Forest ewes throughout the oestrous cycle.<\/jats:p>\n                  <jats:p>The concentration of oestradiol began to rise 12\u201314 h before the onset of oestrus from values of 11\u00b72 \u00b1 0\u00b736 (s.e.m.) pg\/ml during the luteal phase to 21\u00b71 \u00b1 2\u00b701 pg\/ml at \u22128 to 0 h (oestrus). There was no distinct increase during the luteal phase.<\/jats:p>\n                  <jats:p>Circulating progesterone varied in a cyclic manner with the highest values at the mid-luteal phase (3\u00b770 \u00b1 0\u00b728 ng\/ml; n = 28). In five out of six ewes the concentration was still quite high (1\u00b786 \u00b1 0\u00b743 ng\/ml) at 35 h before the onset of oestrus. The concentration declined rapidly thereafter, reaching minimum values about 12 h before oestrus coincident with the increase in oestradiol concentration.<\/jats:p>\n                  <jats:p>Plasma LH increased from very low values of 2\u00b759 \u00b1 0\u00b709 ng\/ml during the luteal phase to 75\u00b73 \u00b1 7\u00b74 ng\/ml about 9 h after the onset of oestrus.<\/jats:p>\n                  <jats:p>Two peaks of plasma FSH concentration were detected after the onset of oestrus. The first peak (171\u00b70\u00b1 35\u00b75 ng\/ml) coincided with the LH peak and the second (133\u00b70 \u00b1 10\u00b77 ng\/ml) occurred about 24 h later at a time when LH values were low. The mean FSH concentration at other times during the cycle was 61\u00b79 \u00b1 2\u00b78 ng\/ml.<\/jats:p>","DOI":"10.1677\/joe.0.0730247","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T17:22:29Z","timestamp":1229016149000},"page":"247-255","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-5","source":"Crossref","is-referenced-by-count":68,"title":["CONCENTRATION OF OESTRADIOL, PROGESTERONE, LUTEINIZING HORMONE AND FOLLICLE-STIMULATING HORMONE IN THE JUGULAR VENOUS PLASMA OF EWES DURING THE OESTROUS CYCLE"],"prefix":"10.1530","volume":"73","author":[{"given":"H. C.","family":"PANT","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. R. N.","family":"HOPKINSON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. J.","family":"FITZPATRICK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/73\/2\/joe_73_2_006.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/73\/2\/247\/132399\/joe_73_2_006.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/73\/2\/247\/132399\/joe_73_2_006.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T14:59:51Z","timestamp":1783609191000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article\/73\/2\/247\/23402\/CONCENTRATION-OF-OESTRADIOL-PROGESTERONE"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,5,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1977,5,1]]}},"URL":"https:\/\/doi.org\/10.1677\/joe.0.0730247","relation":{},"ISSN":["1479-6805","0022-0795"],"issn-type":[{"value":"1479-6805","type":"electronic"},{"value":"0022-0795","type":"print"}],"subject":[],"published":{"date-parts":[[1977,5,1]]}}}