{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T16:14:29Z","timestamp":1783613669101,"version":"3.55.0"},"reference-count":0,"publisher":"Bioscientifica","issue":"2","content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1980,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The effects of progesterone and\/or oestradiol treatment on the ultrastructural appearance of the pancreatic B cells has been studied in ovariectomized Wistar rats. A morphometric examination of the numerical density of dark and light granules in the B cells was therefore performed in each group of experimental rats as well as in control (olive oil-injected) rats.<\/jats:p>\n                  <jats:p>In the oestradiol-treated rats, and especially in the rats with combined oestradiol\/progesterone treatment, the proportions of light and dark granules in the pancreatic B cells changed, compared with control values, in favour of the light granules. This increase in light granule content was comparable to changes in B cells during pregnancy and it is suggested that the secretory activity of the B cells increases during pregnancy in a manner similar to that seen during oestradiol treatment.<\/jats:p>","DOI":"10.1677\/joe.0.0840317","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T17:22:29Z","timestamp":1229016149000},"page":"317-NP","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-5","source":"Crossref","is-referenced-by-count":15,"title":["EFFECTS OF TREATMENT WITH PROGESTERONE AND OESTRADIOL-17\u03b2 ON THE ENDOCRINE PANCREAS IN OVARIECTOMIZED RATS: ULTRASTRUCTURAL VARIATIONS IN THE B CELLS"],"prefix":"10.1530","volume":"84","author":[{"given":"L.","family":"AERTS","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. A.","family":"VAN ASSCHE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"FAURE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. TH.","family":"SUTTER-DUB","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/84\/2\/joe_84_2_018.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/84\/2\/317\/134682\/joe_84_2_018.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article-pdf\/84\/2\/317\/134682\/joe_84_2_018.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T15:32:31Z","timestamp":1783611151000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.bioscientifica.com\/joe\/article\/84\/2\/317\/24119\/EFFECTS-OF-TREATMENT-WITH-PROGESTERONE-AND"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1980,2,1]]}},"URL":"https:\/\/doi.org\/10.1677\/joe.0.0840317","relation":{},"ISSN":["1479-6805","0022-0795"],"issn-type":[{"value":"1479-6805","type":"electronic"},{"value":"0022-0795","type":"print"}],"subject":[],"published":{"date-parts":[[1980,2,1]]}}}