{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:27:18Z","timestamp":1761611238661},"reference-count":0,"publisher":"Bioscientifica","issue":"1","content-domain":{"domain":["joe.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1986,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n        <jats:p>This work was designed to study the effect of the vitamin D content of human milk on the vitamin D status of exclusively breast-fed infants, and the relation between milk and maternal serum concentrations of vitamin D during the first month of lactation. Serum levels of calcium (Ca), phosphorus (P), magnesium (Mg) and 25-hydroxyvitamin D (25-OH-D) were determined in a racially heterogenous population of nursing women, between days 3 and 5 (L<jats:sub>3<\/jats:sub>), 15 and 18 (L<jats:sub>15<\/jats:sub>) and 30 and 45 (L<jats:sub>30<\/jats:sub>) <jats:italic>post partum<\/jats:italic>. The same parameters were determined in the serum of 1-month-old breast-fed infants. Maternal milk samples were obtained at L<jats:sub>3<\/jats:sub>, L<jats:sub>15<\/jats:sub> and L<jats:sub>30<\/jats:sub> and analysed for Ca, P, Mg, vitamin D and 25-OH-D content. Milk levels of Ca, P and Mg were found to be within the range previously described by other authors. No correlation was found between serum and milk levels of vitamin D and 25-OH-D in nursing mothers. The 25-OH-D concentration in milk was related to its vitamin D content and strongly correlated (<jats:italic>P<\/jats:italic> &lt; 0\u00b7001) with the 25-OH-D levels in the serum of exclusively breast-fed infants. No significant changes were observed in maternal serum levels of 1,25-dihydroxyvitamin D (1,25-(OH)<jats:sub>2<\/jats:sub>D<jats:sub>3<\/jats:sub>) measured at L<jats:sub>3<\/jats:sub> and L<jats:sub>30<\/jats:sub>, or between maternal and infant levels of 1,25-(OH)<jats:sub>2<\/jats:sub>D<jats:sub>3<\/jats:sub> at L<jats:sub>30<\/jats:sub>. This study emphasizes the importance of the 25-OH-D content of maternal milk, in being primarily responsible for the vitamin D concentrations found in the serum of exclusively breast-fed infants. In contrast, serum levels of 1,25-(OH)<jats:sub>2<\/jats:sub>D<jats:sub>3<\/jats:sub> measured in the breast-fed baby seemed mainly related to its calcaemia.<\/jats:p>\n        <jats:p><jats:italic>J. Endocr.<\/jats:italic> (1986) <jats:bold>110,<\/jats:bold> 43\u201350<\/jats:p>","DOI":"10.1677\/joe.0.1100043","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T22:52:58Z","timestamp":1229035978000},"page":"43-50","update-policy":"http:\/\/dx.doi.org\/10.1530\/crossmarkpolicy-5","source":"Crossref","is-referenced-by-count":40,"title":["Relationship between the vitamin D content of maternal milk and the vitamin D status of nursing women and breast-fed infants"],"prefix":"10.1530","volume":"110","author":[{"given":"L.","family":"Cancela","sequence":"first","affiliation":[]},{"given":"N.","family":"Le Boulch","sequence":"additional","affiliation":[]},{"given":"L.","family":"Miravet","sequence":"additional","affiliation":[]}],"member":"416","container-title":["Journal of Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/110\/1\/joe_110_1_005.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/joe.bioscientifica.com\/downloadpdf\/journals\/joe\/110\/1\/joe_110_1_005.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T22:19:58Z","timestamp":1609798798000},"score":1,"resource":{"primary":{"URL":"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/110\/1\/joe_110_1_005.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,7]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1677\/joe.0.1100043","relation":{},"ISSN":["0022-0795","1479-6805"],"issn-type":[{"value":"0022-0795","type":"print"},{"value":"1479-6805","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,7]]}}}