{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T02:55:34Z","timestamp":1789786534220,"version":"4.0.1"},"reference-count":75,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,5]]},"DOI":"10.1681\/asn.2012010029","type":"journal-article","created":{"date-parts":[[2012,2,23]],"date-time":"2012-02-23T22:57:53Z","timestamp":1330037873000},"page":"774-780","source":"Crossref","is-referenced-by-count":85,"title":["Molecular Mechanisms of Acid-Base Sensing by the Kidney"],"prefix":"10.1681","volume":"23","author":[{"given":"Dennis","family":"Brown","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten A.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-6-20230208","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s00424-009-0657-z","article-title":"Regulated acid-base transport in the collecting duct.","volume":"458","author":"Wagner","year":"2009","journal-title":"Pflugers Arch"},{"key":"R2-6-20230208","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1152\/physrev.00045.2003","article-title":"Renal vacuolar H+-ATPase.","volume":"84","author":"Wagner","year":"2004","journal-title":"Physiol Rev"},{"key":"R3-6-20230208","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1172\/JCI111871","article-title":"Carbon dioxide causes exocytosis of vesicles containing H+ pumps in isolated perfused proximal and collecting tubules.","volume":"75","author":"Schwartz","year":"1985","journal-title":"J Clin Invest"},{"key":"R4-6-20230208","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1083\/jcb.102.5.1638","article-title":"Regulation of cell pH by Ca+2-mediated exocytotic insertion of H+-ATPases.","volume":"102","author":"van Adelsberg","year":"1986","journal-title":"J Cell Biol"},{"key":"R5-6-20230208","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1172\/JCI200418046","article-title":"Pyk2 activation is integral to acid stimulation of sodium\/hydrogen exchanger 3.","volume":"114","author":"Li","year":"2004","journal-title":"J Clin Invest"},{"key":"R6-6-20230208","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1038\/sj.ki.5002543","article-title":"The acid-activated signaling pathway: Starting with Pyk2 and ending with increased NHE3 activity.","volume":"72","author":"Preisig","year":"2007","journal-title":"Kidney Int"},{"key":"R7-6-20230208","doi-asserted-by":"crossref","first-page":"F358","DOI":"10.1152\/ajprenal.00520.2005","article-title":"Role of a tyrosine kinase in the CO2-induced stimulation of HCO3- reabsorption by rabbit S2 proximal tubules.","volume":"291","author":"Zhou","year":"2006","journal-title":"Am J Physiol Renal Physiol"},{"key":"R8-6-20230208","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/nature01905","article-title":"Proton-sensing G-protein-coupled receptors.","volume":"425","author":"Ludwig","year":"2003","journal-title":"Nature"},{"key":"R9-6-20230208","first-page":"S4","article-title":"Acid-base transport by the renal proximal tubule.","volume":"23","author":"Skelton","year":"2010","journal-title":"J Nephrol"},{"key":"R10-6-20230208","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1046\/j.1523-1755.2002.00418.x","article-title":"Role of c-SRC and ERK in acid-induced activation of NHE3.","volume":"62","author":"Tsuganezawa","year":"2002","journal-title":"Kidney Int"},{"key":"R11-6-20230208","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/ki.2010.264","article-title":"Acid regulation of NaDC-1 requires a functional endothelin B receptor.","volume":"78","author":"Liu","year":"2010","journal-title":"Kidney Int"},{"key":"R12-6-20230208","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1038\/374636a0","article-title":"Out-of-equilibrium CO2\/HCO3- solutions and their use in characterizing a new K\/HCO3 cotransporter.","volume":"374","author":"Zhao","year":"1995","journal-title":"Nature"},{"key":"R13-6-20230208","doi-asserted-by":"crossref","first-page":"3875","DOI":"10.1073\/pnas.0500423102","article-title":"Evidence from renal proximal tubules that HCO3- and solute reabsorption are acutely regulated not by pH but by basolateral HCO3- and CO2.","volume":"102","author":"Zhou","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"R14-6-20230208","first-page":"252A","article-title":"The receptor protein tyrosine phosphatase gamma (RPTPg) is located at the basal (but not lateral) membrane of proximal tubules [abstract].","volume":"21","author":"Skelton","year":"2010","journal-title":"J Am Soc Nephrol"},{"key":"R15-6-20230208","first-page":"80A","article-title":"ErbB1-ErbB2 heterodimer activation in rabbit renal proximal tubules exposed to acute respiratory acidosis [abstract].","volume":"22","author":"Skelton","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"R17-6-20230208","first-page":"1497","article-title":"Identification of a carbonic anhydrase-like domain in the extracellular region of RPTP gamma defines a new subfamily of receptor tyrosine phosphatases.","volume":"13","author":"Barnea","year":"1993","journal-title":"Mol Cell Biol"},{"key":"R18-6-20230208","doi-asserted-by":"crossref","first-page":"F110","DOI":"10.1152\/ajprenal.00516.2006","article-title":"Role of the AT1A receptor in the CO2-induced stimulation of HCO3- reabsorption by renal proximal tubules.","volume":"293","author":"Zhou","year":"2007","journal-title":"Am J Physiol Renal Physiol"},{"key":"R19-6-20230208","doi-asserted-by":"crossref","first-page":"F245","DOI":"10.1152\/ajprenal.00168.2007","article-title":"Role of endogenously secreted angiotensin II in the CO2-induced stimulation of HCO3 reabsorption by renal proximal tubules.","volume":"294","author":"Zhou","year":"2008","journal-title":"Am J Physiol Renal Physiol"},{"key":"R20-6-20230208","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1681\/ASN.2009050477","article-title":"Deletion of the pH sensor GPR4 decreases renal acid excretion.","volume":"21","author":"Sun","year":"2010","journal-title":"J Am Soc Nephrol"},{"key":"R21-6-20230208","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1128\/MCB.01909-06","article-title":"Vascular abnormalities in mice deficient for the G-protein-coupled receptor GPR4 that functions as a pH sensor.","volume":"27","author":"Yang","year":"2007","journal-title":"Mol Cell Biol"},{"key":"R23-6-20230208","doi-asserted-by":"crossref","first-page":"F643","DOI":"10.1152\/ajprenal.00584.2009","article-title":"cAMP stimulates apical V-ATPase accumulation, microvillar elongation, and proton extrusion in kidney collecting duct A-intercalated cells.","volume":"298","author":"P\u0103unescu","year":"2010","journal-title":"Am J Physiol Renal Physiol"},{"key":"R24-6-20230208","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1007\/BF00374794","article-title":"Evidence for an acid pH in rat renal inner medulla: Paired measurements with liquid ion-exchange microelectrodes on collecting ducts and vasa recta.","volume":"426","author":"Kersting","year":"1994","journal-title":"Pflugers Arch"},{"key":"R25-6-20230208","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1126\/science.289.5479.625","article-title":"Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor.","volume":"289","author":"Chen","year":"2000","journal-title":"Science"},{"key":"R26-6-20230208","doi-asserted-by":"crossref","first-page":"15922","DOI":"10.1074\/jbc.M212475200","article-title":"Kinetic properties of \u201csoluble\u201d adenylyl cyclase. Synergism between calcium and bicarbonate.","volume":"278","author":"Litvin","year":"2003","journal-title":"J Biol Chem"},{"key":"R27-6-20230208","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1096\/fj.02-0598fje","article-title":"Compartmentalization of bicarbonate-sensitive adenylyl cyclase in distinct signaling microdomains.","volume":"17","author":"Zippin","year":"2003","journal-title":"FASEB J"},{"key":"R28-6-20230208","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S1043-2760(01)00454-4","article-title":"CO(2)\/HCO(3)(-)-responsive soluble adenylyl cyclase as a putative metabolic sensor.","volume":"12","author":"Zippin","year":"2001","journal-title":"Trends Endocrinol Metab"},{"key":"R29-6-20230208","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1016\/j.cub.2005.10.040","article-title":"Fungal adenylyl cyclase integrates CO2 sensing with cAMP signaling and virulence.","volume":"15","author":"Klengel","year":"2005","journal-title":"Curr Biol"},{"key":"R30-6-20230208","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1128\/EC.5.1.103-111.2006","article-title":"Cryptococcus neoformans senses CO2 through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1.","volume":"5","author":"Mogensen","year":"2006","journal-title":"Eukaryot Cell"},{"key":"R31-6-20230208","doi-asserted-by":"crossref","first-page":"49523","DOI":"10.1074\/jbc.M309543200","article-title":"Bicarbonate-regulated adenylyl cyclase (sAC) is a sensor that regulates pH-dependent V-ATPase recycling.","volume":"278","author":"Pastor-Soler","year":"2003","journal-title":"J Biol Chem"},{"key":"R32-6-20230208","doi-asserted-by":"crossref","first-page":"F130","DOI":"10.1152\/ajprenal.00406.2007","article-title":"Association of soluble adenylyl cyclase with the V-ATPase in renal epithelial cells.","volume":"294","author":"Paunescu","year":"2008","journal-title":"Am J Physiol Renal Physiol"},{"key":"R33-6-20230208","first-page":"F1060","article-title":"Bicarbonate-activated adenylyl cyclase in fluid-transporting tissues.","volume":"264","author":"Mittag","year":"1993","journal-title":"Am J Physiol"},{"key":"R34-6-20230208","doi-asserted-by":"crossref","first-page":"R62","DOI":"10.1152\/ajpregu.00761.2009","article-title":"Modulation of NaCl absorption by [HCO(3)(-)] in the marine teleost intestine is mediated by soluble adenylyl cyclase.","volume":"299","author":"Tresguerres","year":"2010","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"R35-6-20230208","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1073\/pnas.0911790107","article-title":"Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid\/base homeostasis.","volume":"107","author":"Tresguerres","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"R36-6-20230208","doi-asserted-by":"crossref","first-page":"C667","DOI":"10.1152\/ajpcell.00225.2002","article-title":"The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction.","volume":"284","author":"Pushkin","year":"2003","journal-title":"Am J Physiol Cell Physiol"},{"key":"R37-6-20230208","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.jmb.2006.07.045","article-title":"Molecular details of cAMP generation in mammalian cells: A tale of two systems.","volume":"362","author":"Kamenetsky","year":"2006","journal-title":"J Mol Biol"},{"key":"R38-6-20230208","first-page":"1","article-title":"Study of cyclic adenosine monophosphate microdomains in cells.","volume":"307","author":"Mongillo","year":"2005","journal-title":"Methods Mol Biol"},{"key":"R39-6-20230208","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1126\/science.282.5397.2275","article-title":"A family of cAMP-binding proteins that directly activate Rap1.","volume":"282","author":"Kawasaki","year":"1998","journal-title":"Science"},{"key":"R40-6-20230208","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1038\/ncb1101-1020","article-title":"A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase.","volume":"3","author":"Schmidt","year":"2001","journal-title":"Nat Cell Biol"},{"key":"R41-6-20230208","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1038\/ncb1348","article-title":"V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway.","volume":"8","author":"Hurtado-Lorenzo","year":"2006","journal-title":"Nat Cell Biol"},{"key":"R42-6-20230208","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0021-9258(17)42302-7","article-title":"Vacuolar ATPase activity is required for endosomal carrier vesicle formation.","volume":"269","author":"Clague","year":"1994","journal-title":"J Biol Chem"},{"key":"R43-6-20230208","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1242\/jeb.172.1.39","article-title":"The importance of being acid: The role of acidification in intracellular membrane traffic.","volume":"172","author":"Mellman","year":"1992","journal-title":"J Exp Biol"},{"key":"R44-6-20230208","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1083\/jcb.130.4.821","article-title":"Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump.","volume":"130","author":"van Weert","year":"1995","journal-title":"J Cell Biol"},{"key":"R45-6-20230208","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1097\/00041552-200209000-00009","article-title":"Physiological importance of endosomal acidification: Potential role in proximal tubulopathies.","volume":"11","author":"Marshansky","year":"2002","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"R46-6-20230208","doi-asserted-by":"crossref","first-page":"18540","DOI":"10.1074\/jbc.M011577200","article-title":"Intra-endosomal pH-sensitive recruitment of the Arf-nucleotide exchange factor ARNO and Arf6 from cytoplasm to proximal tubule endosomes.","volume":"276","author":"Maranda","year":"2001","journal-title":"J Biol Chem"},{"key":"R47-6-20230208","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ceb.2008.03.015","article-title":"The V-type H+-ATPase in vesicular trafficking: Targeting, regulation and function.","volume":"20","author":"Marshansky","year":"2008","journal-title":"Curr Opin Cell Biol"},{"key":"R48-6-20230208","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1152\/physiolgenomics.00160.2007","article-title":"Genome-wide gene expression profiling reveals renal genes regulated during metabolic acidosis.","volume":"32","author":"Nowik","year":"2008","journal-title":"Physiol Genomics"},{"key":"R49-6-20230208","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/sj.ki.5002581","article-title":"Renal response to metabolic acidosis: Role of mRNA stabilization.","volume":"73","author":"Ibrahim","year":"2008","journal-title":"Kidney Int"},{"key":"R50-6-20230208","doi-asserted-by":"crossref","first-page":"F1066","DOI":"10.1152\/ajprenal.00303.2011","article-title":"Role of AUF1 and HuR in the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in LLC-PK1-F+ cells.","volume":"301","author":"Mufti","year":"2011","journal-title":"Am J Physiol Renal Physiol"},{"key":"R51-6-20230208","doi-asserted-by":"crossref","first-page":"33681","DOI":"10.1074\/jbc.273.50.33681","article-title":"Stimulation by in vivo and in vitro metabolic acidosis of expression of rBSC-1, the Na+-K+(NH4+)-2Cl- cotransporter of the rat medullary thick ascending limb.","volume":"273","author":"Attmane-Elakeb","year":"1998","journal-title":"J Biol Chem"},{"key":"R52-6-20230208","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1097\/01.ASN.0000085023.73801.4A","article-title":"Acid pH increases the stability of BSC1\/NKCC2 mRNA in the medullary thick ascending limb.","volume":"14","author":"Karim","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"R53-6-20230208","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/ki.2009.265","article-title":"Zeta-crystallin mediates the acid pH-induced increase of BSC1 cotransporter mRNA stability.","volume":"76","author":"Szutkowska","year":"2009","journal-title":"Kidney Int"},{"key":"R54-6-20230208","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.cmet.2011.03.022","article-title":"Insulin receptor-related receptor as an extracellular alkali sensor.","volume":"13","author":"Deyev","year":"2011","journal-title":"Cell Metab"},{"key":"R55-6-20230208","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1038\/ki.1997.381","article-title":"Insulin receptor-related receptor expression in non-A intercalated cells in the kidney.","volume":"52","author":"Bates","year":"1997","journal-title":"Kidney Int"},{"key":"R56-6-20230208","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1038\/ki.1997.384","article-title":"Localization of insulin receptor-related receptor in the rat kidney.","volume":"52","author":"Ozaki","year":"1997","journal-title":"Kidney Int"},{"key":"R57-6-20230208","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1085\/jgp.200308990","article-title":"Molecular basis of pH and Ca2+ regulation of aquaporin water permeability.","volume":"123","author":"N\u00e9meth-Cahalan","year":"2004","journal-title":"J Gen Physiol"},{"key":"R58-6-20230208","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4161\/chan.3707","article-title":"Moving the pH gate of the Kir1.1 inward rectifier channel.","volume":"1","author":"Nanazashvili","year":"2007","journal-title":"Channels (Austin"},{"key":"R59-6-20230208","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1038\/sj.embor.7400678","article-title":"Structural and functional analysis of the putative pH sensor in the Kir1.1 (ROMK) potassium channel.","volume":"7","author":"Rapedius","year":"2006","journal-title":"EMBO Rep"},{"key":"R60-6-20230208","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1681\/ASN.2011040414","article-title":"Effects of pH on potassium: New explanations for old observations.","volume":"22","author":"Aronson","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"R61-6-20230208","first-page":"424","article-title":"Molecular physiology of pH-sensitive background K(2P) channels.","volume":"26","author":"Lesage","year":"2011","journal-title":"Physiology (Bethesda"},{"key":"R62-6-20230208","doi-asserted-by":"crossref","first-page":"8215","DOI":"10.1073\/pnas.0400081101","article-title":"Proximal renal tubular acidosis in TASK2 K+ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transport.","volume":"101","author":"Warth","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"R63-6-20230208","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s00424-009-0656-0","article-title":"Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC).","volume":"458","author":"Loffing","year":"2009","journal-title":"Pflugers Arch"},{"key":"R64-6-20230208","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1126\/science.1174601","article-title":"The taste of carbonation.","volume":"326","author":"Chandrashekar","year":"2009","journal-title":"Science"},{"key":"R65-6-20230208","doi-asserted-by":"crossref","first-page":"e20007","DOI":"10.1371\/journal.pone.0020007","article-title":"Sour taste responses in mice lacking PKD channels.","volume":"6","author":"Horio","year":"2011","journal-title":"PLoS ONE"},{"key":"R66-6-20230208","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1038\/nature05084","article-title":"The cells and logic for mammalian sour taste detection.","volume":"442","author":"Huang","year":"2006","journal-title":"Nature"},{"key":"R67-6-20230208","doi-asserted-by":"crossref","first-page":"37241","DOI":"10.1074\/jbc.M404520200","article-title":"pH Sensing by the calcium-sensing receptor.","volume":"279","author":"Quinn","year":"2004","journal-title":"J Biol Chem"},{"key":"R68-6-20230208","doi-asserted-by":"crossref","first-page":"30002","DOI":"10.1074\/jbc.272.48.30002","article-title":"Aspartate substitutions establish the concerted action of P-region glutamates in repeats I and III in forming the protonation site of L-type Ca2+ channels.","volume":"272","author":"Chen","year":"1997","journal-title":"J Biol Chem"},{"key":"R70-6-20230208","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1681\/ASN.2008111205","article-title":"Bicarbonate supplementation slows progression of CKD and improves nutritional status.","volume":"20","author":"de Brito-Ashurst","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"R71-6-20230208","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1038\/ki.2009.6","article-title":"Increased tissue acid mediates a progressive decline in the glomerular filtration rate of animals with reduced nephron mass.","volume":"75","author":"Wesson","year":"2009","journal-title":"Kidney Int"},{"key":"R72-6-20230208","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1172\/JCI112020","article-title":"Pathophysiology of chronic tubulo-interstitial disease in rats. Interactions of dietary acid load, ammonia, and complement component C3.","volume":"76","author":"Nath","year":"1985","journal-title":"J Clin Invest"},{"key":"R73-6-20230208","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/ki.2009.519","article-title":"Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and kidney injury, and better preserved GFR.","volume":"77","author":"Phisitkul","year":"2010","journal-title":"Kidney Int"},{"key":"R74-6-20230208","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/ki.2009.516","article-title":"A basic approach to CKD.","volume":"77","author":"Simon","year":"2010","journal-title":"Kidney Int"},{"key":"R75-6-20230208","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1038\/ki.2010.348","article-title":"Acid retention during kidney failure induces endothelin and aldosterone production which lead to progressive GFR decline, a situation ameliorated by alkali diet.","volume":"78","author":"Wesson","year":"2010","journal-title":"Kidney Int"},{"key":"R76-6-20230208","doi-asserted-by":"crossref","first-page":"F830","DOI":"10.1152\/ajprenal.00587.2010","article-title":"Acid retention accompanies reduced GFR in humans and increases plasma levels of endothelin and aldosterone.","volume":"300","author":"Wesson","year":"2011","journal-title":"Am J Physiol Renal Physiol"},{"key":"R77-6-20230208","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1681\/ASN.2010111181","article-title":"Estimated GFR, albuminuria, and complications of chronic kidney disease.","volume":"22","author":"Inker","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"R78-6-20230208","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1681\/ASN.2010101077","article-title":"Measured GFR does not outperform estimated GFR in predicting CKD-related complications.","volume":"22","author":"Hsu","year":"2011","journal-title":"J Am Soc Nephrol"}],"container-title":["Journal of the American Society of Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00001751-201205000-00006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T19:31:21Z","timestamp":1786131081000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00001751-201205000-00006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5]]},"references-count":75,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1681\/asn.2012010029","relation":{},"ISSN":["1046-6673"],"issn-type":[{"value":"1046-6673","type":"print"}],"subject":[],"published":{"date-parts":[[2012,5]]}}}