{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T01:15:56Z","timestamp":1793927756216,"version":"4.8.0"},"reference-count":224,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1681\/asn.2012010047","type":"journal-article","created":{"date-parts":[[2012,12,22]],"date-time":"2012-12-22T20:34:21Z","timestamp":1356208461000},"page":"337-351","source":"Crossref","is-referenced-by-count":268,"title":["Frailty and Protein-Energy Wasting in Elderly Patients with End Stage Kidney Disease"],"prefix":"10.1681","volume":"24","author":[{"given":"Jun Chul","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamyar","family":"Kalantar-Zadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel D.","family":"Kopple","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-6-20230208","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1097\/01.ASN.0000067656.48829.0E","article-title":"Geriatric nephrology is coming of age.","volume":"14","author":"Oreopoulos","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"R2-6-20230208","first-page":"502","article-title":"Old age and frailty in the dialysis population.","volume":"23","author":"Brown","year":"2010","journal-title":"J Nephrol"},{"key":"R3-6-20230208","first-page":"S11","article-title":"Geriatric nephrology.","volume":"23","author":"Cavalli","year":"2010","journal-title":"J Nephrol"},{"key":"R5-6-20230208","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1053\/j.ackd.2008.01.008","article-title":"Geriatric hemodialysis rehabilitation care.","volume":"15","author":"Jassal","year":"2008","journal-title":"Adv Chronic Kidney Dis"},{"key":"R6-6-20230208","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.1681\/ASN.2007020221","article-title":"Significance of frailty among dialysis patients.","volume":"18","author":"Johansen","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"R7-6-20230208","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1080\/08860220802669891","article-title":"Malnutrition in the elderly patient on dialysis.","volume":"31","author":"Lacquaniti","year":"2009","journal-title":"Ren Fail"},{"key":"R8-6-20230208","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1159\/000101827","article-title":"Kidney function and sarcopenia in the United States general population: NHANES III.","volume":"27","author":"Foley","year":"2007","journal-title":"Am J Nephrol"},{"key":"R9-6-20230208","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.semnephrol.2008.10.006","article-title":"Causes and prevention of protein-energy wasting in chronic kidney failure.","volume":"29","author":"Dukkipati","year":"2009","journal-title":"Semin Nephrol"},{"key":"R10-6-20230208","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/ki.2008.62","article-title":"Functional dependencies among the elderly on hemodialysis.","volume":"73","author":"Cook","year":"2008","journal-title":"Kidney Int"},{"key":"R11-6-20230208","doi-asserted-by":"crossref","first-page":"M146","DOI":"10.1093\/gerona\/56.3.M146","article-title":"Frailty in older adults: Evidence for a phenotype.","volume":"56","author":"Fried","year":"2001","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R12-6-20230208","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1053\/j.ajkd.2003.12.049","article-title":"The presence of frailty in elderly persons with chronic renal insufficiency.","volume":"43","author":"Shlipak","year":"2004","journal-title":"Am J Kidney Dis"},{"key":"R13-6-20230208","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.amjmed.2009.01.026","article-title":"Frailty and chronic kidney disease: The Third National Health and Nutrition Evaluation Survey.","volume":"122","author":"Wilhelm-Leen","year":"2009","journal-title":"Am J Med"},{"key":"R14-6-20230208","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/sj.ki.5002585","article-title":"A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease.","volume":"73","author":"Fouque","year":"2008","journal-title":"Kidney Int"},{"key":"R15-6-20230208","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1093\/ajcn\/65.5.1544","article-title":"McCollum Award Lecture, 1996: Protein-energy malnutrition in maintenance dialysis patients.","volume":"65","author":"Kopple","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"R17-6-20230208","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.3390\/ijms11041509","article-title":"Oxidative stress, molecular inflammation and sarcopenia.","volume":"11","author":"Meng","year":"2010","journal-title":"Int J Mol Sci"},{"key":"R18-6-20230208","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1093\/ndt\/gfl721","article-title":"Markers of oxidative stress in the skeletal muscle of patients on haemodialysis.","volume":"22","author":"Crowe","year":"2007","journal-title":"Nephrol Dial Transplant"},{"key":"R19-6-20230208","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1152\/japplphysiol.00133.2007","article-title":"Oxidative protein damage is associated with poor grip strength among older women living in the community.","volume":"103","author":"Howard","year":"2007","journal-title":"J Appl Physiol"},{"key":"R20-6-20230208","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/j.amjmed.2007.07.028","article-title":"Oxidative stress and severe walking disability among older women.","volume":"120","author":"Semba","year":"2007","journal-title":"Am J Med"},{"key":"R21-6-20230208","first-page":"1121","article-title":"Epidemiologic and methodologic problems in determining nutritional status of older persons. Proceedings of a conference. Albuquerque, New Mexico, October 19-21, 1988.","volume":"50","author":"Rosenberg","year":"1989","journal-title":"Am J Clin Nutr"},{"key":"R22-6-20230208","doi-asserted-by":"crossref","first-page":"990S","DOI":"10.1093\/jn\/127.5.990S","article-title":"Sarcopenia: Origins and clinical relevance.","volume":"127","author":"Rosenberg","year":"1997","journal-title":"J Nutr"},{"key":"R23-6-20230208","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1093\/gerona\/63.8.829","article-title":"Sarcopenia =\/= dynapenia.","volume":"63","author":"Clark","year":"2008","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R24-6-20230208","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.jamda.2011.04.014","article-title":"Sarcopenia with limited mobility: An international consensus.","volume":"12","author":"Morley","year":"2011","journal-title":"J Am Med Dir Assoc"},{"key":"R25-6-20230208","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1152\/jappl.2000.88.4.1321","article-title":"Aging of skeletal muscle: A 12-yr longitudinal study.","volume":"88","author":"Frontera","year":"2000","journal-title":"J Appl Physiol"},{"key":"R26-6-20230208","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.2215\/CJN.02080310","article-title":"Mid-arm muscle circumference and quality of life and survival in maintenance hemodialysis patients.","volume":"5","author":"Noori","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"key":"R27-6-20230208","doi-asserted-by":"crossref","first-page":"991","DOI":"10.4065\/mcp.2010.0336","article-title":"The obesity paradox and mortality associated with surrogates of body size and muscle mass in patients receiving hemodialysis.","volume":"85","author":"Kalantar-Zadeh","year":"2010","journal-title":"Mayo Clin Proc"},{"key":"R28-6-20230208","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.3945\/ajcn.2009.28047","article-title":"Longitudinal study of muscle strength, quality, and adipose tissue infiltration.","volume":"90","author":"Delmonico","year":"2009","journal-title":"Am J Clin Nutr"},{"key":"R29-6-20230208","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1093\/gerona\/61.10.1059","article-title":"The loss of skeletal muscle strength, mass, and quality in older adults: The health, aging and body composition study.","volume":"61","author":"Goodpaster","year":"2006","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R30-6-20230208","doi-asserted-by":"crossref","first-page":"B209","DOI":"10.1093\/gerona\/56.5.B209","article-title":"Longitudinal muscle strength changes in older adults: Influence of muscle mass, physical activity, and health.","volume":"56","author":"Hughes","year":"2001","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R31-6-20230208","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1093\/ndt\/gfh784","article-title":"Endurance exercise training during haemodialysis improves strength, power, fatigability and physical performance in maintenance haemodialysis patients.","volume":"20","author":"Storer","year":"2005","journal-title":"Nephrol Dial Transplant"},{"key":"R32-6-20230208","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1532-5415.2000.tb04694.x","article-title":"Skeletal muscle mass and muscle strength in relation to lower-extremity performance in older men and women.","volume":"48","author":"Visser","year":"2000","journal-title":"J Am Geriatr Soc"},{"key":"R33-6-20230208","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1093\/gerona\/61.1.72","article-title":"Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort.","volume":"61","author":"Newman","year":"2006","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R34-6-20230208","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1093\/gerona\/gln031","article-title":"Skeletal muscle and mortality results from the InCHIANTI Study.","volume":"64","author":"Cesari","year":"2009","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R35-6-20230208","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/j.1749-6632.2000.tb06498.x","article-title":"Body composition in healthy aging.","volume":"904","author":"Baumgartner","year":"2000","journal-title":"Ann N Y Acad Sci"},{"key":"R36-6-20230208","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/sj.ijo.0803417","article-title":"Dual energy X-ray absorptiometry body composition and aging in a population-based older cohort.","volume":"31","author":"Shaw","year":"2007","journal-title":"Int J Obes (Lond"},{"key":"R37-6-20230208","doi-asserted-by":"crossref","first-page":"E366","DOI":"10.1152\/ajpendo.2000.279.2.E366","article-title":"Weight stability masks sarcopenia in elderly men and women.","volume":"279","author":"Gallagher","year":"2000","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"R38-6-20230208","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1146\/annurev.nutr.21.1.343","article-title":"Nutritional management of maintenance dialysis patients: Why aren\u2019t we doing better?","volume":"21","author":"Mehrotra","year":"2001","journal-title":"Annu Rev Nutr"},{"key":"R39-6-20230208","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1046\/j.1523-1755.1998.00812.x","article-title":"Factors predicting malnutrition in hemodialysis patients: A cross-sectional study.","volume":"53","author":"Qureshi","year":"1998","journal-title":"Kidney Int"},{"key":"R40-6-20230208","first-page":"M596","article-title":"Effect of aging on the body composition of dialyzed subjects. Comparison with normal subjects.","volume":"39","author":"Biasioli","year":"1993","journal-title":"ASAIO J"},{"key":"R41-6-20230208","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0272-6386(03)00654-1","article-title":"Association between inflammatory mediators and muscle mass in long-term hemodialysis patients.","volume":"42","author":"Kaizu","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"R42-6-20230208","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1093\/ndt\/gfl064","article-title":"Patients receiving maintenance dialysis have more severe functionally significant skeletal muscle wasting than patients with dialysis-independent chronic kidney disease.","volume":"21","author":"McIntyre","year":"2006","journal-title":"Nephrol Dial Transplant"},{"key":"R43-6-20230208","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/ndt\/gfh643","article-title":"Association of age with muscle mass, fat mass and fat distribution in non-diabetic haemodialysis patients.","volume":"20","author":"Ohkawa","year":"2005","journal-title":"Nephrol Dial Transplant"},{"key":"R44-6-20230208","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1093\/ndt\/14.10.2427","article-title":"Altered abdominal fat distribution and its association with the serum lipid profile in non-diabetic haemodialysis patients.","volume":"14","author":"Odamaki","year":"1999","journal-title":"Nephrol Dial Transplant"},{"key":"R45-6-20230208","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1111\/j.1532-5415.2005.53405.x","article-title":"Frailty: Emergence and consequences in women aged 65 and older in the Women\u2019s Health Initiative Observational Study.","volume":"53","author":"Woods","year":"2005","journal-title":"J Am Geriatr Soc"},{"key":"R46-6-20230208","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s00198-009-1059-y","article-title":"Sarcopenia: Etiology, clinical consequences, intervention, and assessment.","volume":"21","author":"Lang","year":"2010","journal-title":"Osteoporos Int"},{"key":"R47-6-20230208","doi-asserted-by":"crossref","first-page":"4493","DOI":"10.1210\/jc.2010-0859","article-title":"Genetic studies reveal the role of the endocrine and metabolic systems in aging.","volume":"95","author":"Barzilai","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"R48-6-20230208","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cger.2010.08.006","article-title":"The biology of aging and frailty.","volume":"27","author":"Fedarko","year":"2011","journal-title":"Clin Geriatr Med"},{"key":"R49-6-20230208","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.mce.2008.11.025","article-title":"Insulin\/IGF-1 and ROS signaling pathway cross-talk in aging and longevity determination.","volume":"299","author":"Papaconstantinou","year":"2009","journal-title":"Mol Cell Endocrinol"},{"key":"R50-6-20230208","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.ghir.2008.05.005","article-title":"Role of the GH\/IGF-1 axis in lifespan and healthspan: Lessons from animal models.","volume":"18","author":"Berryman","year":"2008","journal-title":"Growth Horm IGF Res"},{"key":"R51-6-20230208","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM199007053230101","article-title":"Effects of human growth hormone in men over 60 years old.","volume":"323","author":"Rudman","year":"1990","journal-title":"N Engl J Med"},{"key":"R52-6-20230208","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/bjp.2008.153","article-title":"Regulation of muscle mass by growth hormone and IGF-I.","volume":"154","author":"Velloso","year":"2008","journal-title":"Br J Pharmacol"},{"key":"R53-6-20230208","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1210\/er.2006-0052","article-title":"The growth hormone\/insulin-like growth factor-I axis in exercise and sport.","volume":"28","author":"Gibney","year":"2007","journal-title":"Endocr Rev"},{"key":"R54-6-20230208","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1677\/JOE-09-0431","article-title":"The GH\/IGF1 axis and signaling pathways in the muscle and bone: Mechanisms underlying age-related skeletal muscle wasting and osteoporosis.","volume":"205","author":"Perrini","year":"2010","journal-title":"J Endocrinol"},{"key":"R55-6-20230208","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1681\/ASN.2010010046","article-title":"Sirtuins and their relevance to the kidney.","volume":"21","author":"Hao","year":"2010","journal-title":"J Am Soc Nephrol"},{"key":"R56-6-20230208","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1681\/ASN.2010060643","article-title":"Mitochondrial biogenesis in kidney disease.","volume":"22","author":"Weinberg","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"R57-6-20230208","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1146\/annurev.genet.39.110304.095751","article-title":"A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine.","volume":"39","author":"Wallace","year":"2005","journal-title":"Annu Rev Genet"},{"key":"R58-6-20230208","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0009-8981(03)00003-2","article-title":"Protein carbonyl groups as biomarkers of oxidative stress.","volume":"329","author":"Dalle-Donne","year":"2003","journal-title":"Clin Chim Acta"},{"key":"R59-6-20230208","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/S0891-5849(02)00780-3","article-title":"Oxidatively modified proteins in aging and disease.","volume":"32","author":"Beal","year":"2002","journal-title":"Free Radic Biol Med"},{"key":"R60-6-20230208","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1007\/s00018-010-0597-y","article-title":"Apoptosis and aging: Increased resistance to apoptosis enhances the aging process.","volume":"68","author":"Salminen","year":"2011","journal-title":"Cell Mol Life Sci"},{"key":"R61-6-20230208","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.molmed.2009.03.004","article-title":"Regulation of the aging process by autophagy.","volume":"15","author":"Salminen","year":"2009","journal-title":"Trends Mol Med"},{"key":"R62-6-20230208","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/nrm2241","article-title":"How stem cells age and why this makes us grow old.","volume":"8","author":"Sharpless","year":"2007","journal-title":"Nat Rev Mol Cell Biol"},{"key":"R63-6-20230208","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1042\/CS20100385","article-title":"Healthy aging and disease: Role for telomere biology?","volume":"120","author":"Zhu","year":"2011","journal-title":"Clin Sci (Lond"},{"key":"R64-6-20230208","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1681\/ASN.2010060662","article-title":"Telomeres and telomerase in renal health.","volume":"22","author":"Wills","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"R65-6-20230208","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1681\/ASN.2010020205","article-title":"Cell senescence in the aging kidney.","volume":"21","author":"Yang","year":"2010","journal-title":"J Am Soc Nephrol"},{"key":"R66-6-20230208","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1742-4933-3-12","article-title":"Is inflammaging an auto[innate]immunity subclinical syndrome?","volume":"3","author":"Giunta","year":"2006","journal-title":"Immun Ageing"},{"key":"R67-6-20230208","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/jemt.10203","article-title":"Molecular inflammation hypothesis of aging based on the anti-aging mechanism of calorie restriction.","volume":"59","author":"Chung","year":"2002","journal-title":"Microsc Res Tech"},{"key":"R68-6-20230208","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.arr.2008.07.002","article-title":"Molecular inflammation: Underpinnings of aging and age-related diseases.","volume":"8","author":"Chung","year":"2009","journal-title":"Ageing Res Rev"},{"key":"R69-6-20230208","doi-asserted-by":"crossref","first-page":"353","DOI":"10.4065\/81.3.353","article-title":"High prevalence of vitamin D inadequacy and implications for health.","volume":"81","author":"Holick","year":"2006","journal-title":"Mayo Clin Proc"},{"key":"R70-6-20230208","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1093\/ajcn\/58.6.882","article-title":"Effects of skin thickness, age, body fat, and sunlight on serum 25-hydroxyvitamin D.","volume":"58","author":"Need","year":"1993","journal-title":"Am J Clin Nutr"},{"key":"R71-6-20230208","doi-asserted-by":"crossref","first-page":"5766","DOI":"10.1210\/jc.2003-030604","article-title":"Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): The Longitudinal Aging Study Amsterdam.","volume":"88","author":"Visser","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"R72-6-20230208","doi-asserted-by":"crossref","first-page":"537S","DOI":"10.1093\/ajcn\/88.2.537S","article-title":"Serum 25-hydroxyvitamin D and functional outcomes in the elderly.","volume":"88","author":"Dawson-Hughes","year":"2008","journal-title":"Am J Clin Nutr"},{"key":"R73-6-20230208","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1159\/000087203","article-title":"Low-dose vitamin D prevents muscular atrophy and reduces falls and hip fractures in women after stroke: A randomized controlled trial.","volume":"20","author":"Sato","year":"2005","journal-title":"Cerebrovasc Dis"},{"key":"R74-6-20230208","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1053\/j.jrn.2007.06.001","article-title":"Relationship between vitamin D and muscle size and strength in patients on hemodialysis.","volume":"17","author":"Gordon","year":"2007","journal-title":"J Ren Nutr"},{"key":"R75-6-20230208","doi-asserted-by":"crossref","first-page":"5138","DOI":"10.1210\/en.2003-0502","article-title":"Deletion of vitamin D receptor gene in mice results in abnormal skeletal muscle development with deregulated expression of myoregulatory transcription factors.","volume":"144","author":"Endo","year":"2003","journal-title":"Endocrinology"},{"key":"R76-6-20230208","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1097\/MCO.0b013e328331c707","article-title":"Vitamin D and its role in skeletal muscle.","volume":"12","author":"Ceglia","year":"2009","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"R77-6-20230208","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1046\/j.1474-9728.2003.00011.x","article-title":"Neural control of aging skeletal muscle.","volume":"2","author":"Delbono","year":"2003","journal-title":"Aging Cell"},{"key":"R78-6-20230208","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1159\/000154929","article-title":"Functional decline in cognitive impairment\u2014the relationship between physical and cognitive function.","volume":"31","author":"Auyeung","year":"2008","journal-title":"Neuroepidemiology"},{"key":"R79-6-20230208","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1001\/archneurol.2009.240","article-title":"Association of muscle strength with the risk of Alzheimer disease and the rate of cognitive decline in community-dwelling older persons.","volume":"66","author":"Boyle","year":"2009","journal-title":"Arch Neurol"},{"key":"R80-6-20230208","doi-asserted-by":"crossref","first-page":"1011S","DOI":"10.1093\/jn\/127.5.1011S","article-title":"Evidence for nervous system degeneration with advancing age.","volume":"127","author":"Lexell","year":"1997","journal-title":"J Nutr"},{"key":"R81-6-20230208","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.1152\/jn.00685.2005","article-title":"Doublet discharges in motoneurons of young and older adults.","volume":"95","author":"Christie","year":"2006","journal-title":"J Neurophysiol"},{"key":"R82-6-20230208","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.neurobiolaging.2005.06.009","article-title":"Axonal degeneration affects muscle density in older men and women.","volume":"27","author":"Lauretani","year":"2006","journal-title":"Neurobiol Aging"},{"key":"R83-6-20230208","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1096\/fj.04-2870fje","article-title":"Muscle fiber specific apoptosis and TNF-alpha signaling in sarcopenia are attenuated by life-long calorie restriction.","volume":"19","author":"Phillips","year":"2005","journal-title":"FASEB J"},{"key":"R84-6-20230208","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1093\/ndt\/13.3.685","article-title":"The effects of exercise training on muscle atrophy in haemodialysis patients.","volume":"13","author":"Kouidi","year":"1998","journal-title":"Nephrol Dial Transplant"},{"key":"R85-6-20230208","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1126\/science.1087573","article-title":"Notch-mediated restoration of regenerative potential to aged muscle.","volume":"302","author":"Conboy","year":"2003","journal-title":"Science"},{"key":"R86-6-20230208","doi-asserted-by":"crossref","first-page":"E151","DOI":"10.1152\/ajpendo.00278.2006","article-title":"Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderly.","volume":"292","author":"Verdijk","year":"2007","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"R87-6-20230208","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1042\/BC20070085","article-title":"Replicative aging down-regulates the myogenic regulatory factors in human myoblasts.","volume":"100","author":"Bigot","year":"2008","journal-title":"Biol Cell"},{"key":"R88-6-20230208","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1111\/j.1440-1681.2007.04752.x","article-title":"Age-related changes in the structure and function of skeletal muscles.","volume":"34","author":"Faulkner","year":"2007","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"R89-6-20230208","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1136\/jnnp.36.2.174","article-title":"Physiological changes in ageing muscles.","volume":"36","author":"Campbell","year":"1973","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"R90-6-20230208","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1096\/fj.04-2640fje","article-title":"Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle.","volume":"19","author":"Cuthbertson","year":"2005","journal-title":"FASEB J"},{"key":"R91-6-20230208","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1469-7580.2006.00548.x","article-title":"Adaptability of elderly human muscles and tendons to increased loading.","volume":"208","author":"Narici","year":"2006","journal-title":"J Anat"},{"key":"R92-6-20230208","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1148\/radiographics.13.2.8460225","article-title":"Musculoskeletal manifestations of chronic renal insufficiency.","volume":"13","author":"Murphey","year":"1993","journal-title":"Radiographics"},{"key":"R93-6-20230208","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1093\/rheumatology\/kei022","article-title":"Role of secondary hyperparathyroidism in spontaneous rupture of the quadriceps tendon complicating chronic renal failure.","volume":"45","author":"Thaunat","year":"2006","journal-title":"Rheumatology (Oxford"},{"key":"R94-6-20230208","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1093\/ndt\/12.9.1988","article-title":"Nontraumatic bilateral rupture of patellar tendons in a diabetic dialysis patient with secondary hyperparathyroidism.","volume":"12","author":"Kalantar-Zadeh","year":"1997","journal-title":"Nephrol Dial Transplant"},{"key":"R95-6-20230208","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1038\/sj.ki.5001754","article-title":"Incidence and risk factors for hip or other bone fractures among hemodialysis patients in the Dialysis Outcomes and Practice Patterns Study.","volume":"70","author":"Jadoul","year":"2006","journal-title":"Kidney Int"},{"key":"R96-6-20230208","doi-asserted-by":"crossref","first-page":"3377","DOI":"10.1093\/ndt\/gfm508","article-title":"Towards the prevention of bone fractures in dialysed patients?","volume":"22","author":"Jadoul","year":"2007","journal-title":"Nephrol Dial Transplant"},{"key":"R97-6-20230208","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1093\/ndt\/14.7.1679","article-title":"Nutritional status of haemodialysis patients: A French national cooperative study.","volume":"14","author":"Aparicio","year":"1999","journal-title":"Nephrol Dial Transplant"},{"key":"R98-6-20230208","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1123\/jpah.7.5.584","article-title":"No strain, no gain: Psychosocial predictors of physical activity across the adult lifespan.","volume":"7","author":"Cotter","year":"2010","journal-title":"J Phys Act Health"},{"key":"R99-6-20230208","doi-asserted-by":"crossref","first-page":"2564","DOI":"10.1046\/j.1523-1755.2000.00116.x","article-title":"Physical activity levels in patients on hemodialysis and healthy sedentary controls.","volume":"57","author":"Johansen","year":"2000","journal-title":"Kidney Int"},{"key":"R100-6-20230208","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.annepidem.2008.09.008","article-title":"Exercise and limitations in physical activity levels among new dialysis patients in the United States: An epidemiologic study.","volume":"18","author":"Stack","year":"2008","journal-title":"Ann Epidemiol"},{"key":"R101-6-20230208","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1038\/ki.2010.312","article-title":"Low level of self-reported physical activity in ambulatory patients new to dialysis.","volume":"78","author":"Johansen","year":"2010","journal-title":"Kidney Int"},{"key":"R102-6-20230208","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1053\/j.jrn.2007.01.003","article-title":"Body composition and physical activity in end-stage renal disease.","volume":"17","author":"Majchrzak","year":"2007","journal-title":"J Ren Nutr"},{"key":"R103-6-20230208","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1744-9987.2009.00750.x","article-title":"Physical activity is necessary to prevent deterioration of the walking ability of patients undergoing maintenance hemodialysis.","volume":"14","author":"Kutsuna","year":"2010","journal-title":"Ther Apher Dial"},{"key":"R104-6-20230208","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1053\/j.ajkd.2004.12.013","article-title":"Association of physical activity with mortality in the US dialysis population.","volume":"45","author":"Stack","year":"2005","journal-title":"Am J Kidney Dis"},{"key":"R105-6-20230208","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/sj.ki.5001572","article-title":"Anorexia in hemodialysis patients: An update.","volume":"70","author":"Bossola","year":"2006","journal-title":"Kidney Int"},{"key":"R106-6-20230208","doi-asserted-by":"crossref","first-page":"33","DOI":"10.2215\/CJN.00340705","article-title":"Daily hemodialysis: A systematic review.","volume":"1","author":"Suri","year":"2006","journal-title":"Clin J Am Soc Nephrol"},{"key":"R107-6-20230208","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1079\/BJN20031004","article-title":"Daily protein intakes and eating patterns in young and elderly French.","volume":"90","author":"Rousset","year":"2003","journal-title":"Br J Nutr"},{"key":"R108-6-20230208","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s11255-010-9875-8","article-title":"Hemodialysis duration impairs food intake and nutritional parameters in chronic kidney disease patients.","volume":"44","author":"Mekki","year":"2010","journal-title":"Int Urol Nephrol"},{"key":"R109-6-20230208","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1097\/MNH.0b013e32830d5bfa","article-title":"Hypercatabolism in dialysis patients.","volume":"17","author":"Raj","year":"2008","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"R110-6-20230208","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1093\/ndt\/13.6.1476","article-title":"Anorexigen (TNF-alpha, cholecystokinin) and orexigen (neuropeptide Y) plasma levels in peritoneal dialysis (PD) patients: Their relationship with nutritional parameters.","volume":"13","author":"Aguilera","year":"1998","journal-title":"Nephrol Dial Transplant"},{"key":"R111-6-20230208","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1038\/sj.ki.5000182","article-title":"Leptin and inflammation-associated cachexia in chronic kidney disease.","volume":"69","author":"Mak","year":"2006","journal-title":"Kidney Int"},{"key":"R112-6-20230208","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1111\/j.1525-139X.2009.00664.x","article-title":"Inflammation and insulin resistance as novel mechanisms of wasting in chronic dialysis patients.","volume":"22","author":"da Costa","year":"2009","journal-title":"Semin Dial"},{"key":"R113-6-20230208","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1093\/ajcn\/82.4.801","article-title":"Inflammation is associated with increased energy expenditure in patients with chronic kidney disease.","volume":"82","author":"Utaka","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"R114-6-20230208","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1097\/JES.0b013e3181b7b3d9","article-title":"Exercise training as a treatment for chronic inflammation in the elderly.","volume":"37","author":"Nicklas","year":"2009","journal-title":"Exerc Sport Sci Rev"},{"key":"R115-6-20230208","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1111\/j.1523-1755.2005.00695.x","article-title":"Skeletal muscle, cytokines, and oxidative stress in end-stage renal disease.","volume":"68","author":"Raj","year":"2005","journal-title":"Kidney Int"},{"key":"R116-6-20230208","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1515\/CCLM.2002.175","article-title":"Effect of hemodialysis on the oxidative stress and antioxidants.","volume":"40","author":"Dursun","year":"2002","journal-title":"Clin Chem Lab Med"},{"key":"R117-6-20230208","doi-asserted-by":"crossref","first-page":"10","DOI":"10.2174\/1874609810801010010","article-title":"The mitochondrial free radical theory of aging: A critical view.","volume":"1","author":"Sanz","year":"2008","journal-title":"Curr Aging Sci"},{"key":"R118-6-20230208","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.tcb.2011.06.008","article-title":"Taking a \u201cgood\u201d look at free radicals in the aging process.","volume":"21","author":"Hekimi","year":"2011","journal-title":"Trends Cell Biol"},{"key":"R119-6-20230208","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1046\/j.1523-1755.2000.00443.x","article-title":"Plasma protein thiol oxidation and carbonyl formation in chronic renal failure.","volume":"58","author":"Himmelfarb","year":"2000","journal-title":"Kidney Int"},{"key":"R120-6-20230208","doi-asserted-by":"crossref","first-page":"691","DOI":"10.2215\/CJN.04291007","article-title":"Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation.","volume":"3","author":"Linden","year":"2008","journal-title":"Clin J Am Soc Nephrol"},{"key":"R121-6-20230208","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1093\/ndt\/16.suppl_4.8","article-title":"Advanced glycation and lipoxidation end products: Reactive carbonyl compounds-related uraemic toxicity.","volume":"16","author":"Miyata","year":"2001","journal-title":"Nephrol Dial Transplant"},{"key":"R122-6-20230208","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1525-139X.2007.00282.x","article-title":"Familial clustering of chronic kidney disease.","volume":"20","author":"Satko","year":"2007","journal-title":"Semin Dial"},{"key":"R123-6-20230208","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1053\/j.ajkd.2005.09.027","article-title":"CKD risk factors reported by primary care physicians: Do guidelines make a difference?","volume":"47","author":"Lea","year":"2006","journal-title":"Am J Kidney Dis"},{"key":"R124-6-20230208","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1093\/ndt\/gfn056","article-title":"Epigenetics\u2014a helpful tool to better understand processes in clinical nephrology?","volume":"23","author":"Stenvinkel","year":"2008","journal-title":"Nephrol Dial Transplant"},{"key":"R125-6-20230208","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.arr.2009.11.001","article-title":"Genetics vs. entropy: Longevity factors suppress the NF-kappaB-driven entropic aging process.","volume":"9","author":"Salminen","year":"2010","journal-title":"Ageing Res Rev"},{"key":"R126-6-20230208","doi-asserted-by":"crossref","first-page":"2630","DOI":"10.1097\/01.ASN.0000139492.36400.6C","article-title":"Chronic uremia attenuates growth hormone-induced signal transduction in skeletal muscle.","volume":"15","author":"Sun","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"R127-6-20230208","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.1525-139X.2010.00763.x","article-title":"Insulin resistance and protein energy metabolism in patients with advanced chronic kidney disease.","volume":"23","author":"Siew","year":"2010","journal-title":"Semin Dial"},{"key":"R128-6-20230208","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/sj.ki.5001984","article-title":"Insulin resistance is associated with skeletal muscle protein breakdown in non-diabetic chronic hemodialysis patients.","volume":"71","author":"Siew","year":"2007","journal-title":"Kidney Int"},{"key":"R129-6-20230208","doi-asserted-by":"crossref","first-page":"1128S","DOI":"10.3945\/ajcn.2010.28608B","article-title":"Review of muscle wasting associated with chronic kidney disease.","volume":"91","author":"Workeneh","year":"2010","journal-title":"Am J Clin Nutr"},{"key":"R130-6-20230208","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1111\/j.1523-1755.2005.00699.x","article-title":"Accelerated lean body mass loss in incident chronic dialysis patients with diabetes mellitus.","volume":"68","author":"Pupim","year":"2005","journal-title":"Kidney Int"},{"key":"R131-6-20230208","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1111\/j.1523-1755.2005.00605.x","article-title":"Increased muscle protein breakdown in chronic hemodialysis patients with type 2 diabetes mellitus.","volume":"68","author":"Pupim","year":"2005","journal-title":"Kidney Int"},{"key":"R132-6-20230208","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.2337\/dc06-2537","article-title":"Accelerated loss of skeletal muscle strength in older adults with type 2 diabetes: The health, aging, and body composition study.","volume":"30","author":"Park","year":"2007","journal-title":"Diabetes Care"},{"key":"R133-6-20230208","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1172\/JCI118499","article-title":"Impaired actions of insulin-like growth factor 1 on protein Synthesis and degradation in skeletal muscle of rats with chronic renal failure. Evidence for a postreceptor defect.","volume":"97","author":"Ding","year":"1996","journal-title":"J Clin Invest"},{"key":"R134-6-20230208","doi-asserted-by":"crossref","first-page":"2975","DOI":"10.1681\/ASN.2006070794","article-title":"Exercise in maintenance hemodialysis patients induces transcriptional changes in genes favoring anabolic muscle.","volume":"18","author":"Kopple","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"R135-6-20230208","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1111\/j.1523-1755.2005.00409.x","article-title":"Skeletal muscle mRNA for IGF-IEa, IGF-II, and IGF-I receptor is decreased in sedentary chronic hemodialysis patients.","volume":"68","author":"Wang","year":"2005","journal-title":"Kidney Int"},{"key":"R136-6-20230208","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1093\/ndt\/gfq397","article-title":"Prevalence and clinical implications of testosterone deficiency in men with end-stage renal disease.","volume":"26","author":"Carrero","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"R137-6-20230208","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1210\/jcem.87.2.8201","article-title":"Age trends in the level of serum testosterone and other hormones in middle-aged men: Longitudinal results from the Massachusetts male aging study.","volume":"87","author":"Feldman","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"R138-6-20230208","doi-asserted-by":"crossref","first-page":"3806","DOI":"10.1210\/jc.2009-0417","article-title":"Sex hormones and frailty in older men: The osteoporotic fractures in men (MrOS) study.","volume":"94","author":"Cawthon","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"R139-6-20230208","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM199607043350101","article-title":"The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men.","volume":"335","author":"Bhasin","year":"1996","journal-title":"N Engl J Med"},{"key":"R140-6-20230208","first-page":"2008","article-title":"Ubiquitin, proteasomes and proteolytic mechanisms activated by kidney disease.","volume":"795-9","author":"Rajan","year":"1782","journal-title":"Biochim Biophys Acta"},{"key":"R141-6-20230208","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1056\/NEJM199612193352507","article-title":"Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway.","volume":"335","author":"Mitch","year":"1996","journal-title":"N Engl J Med"},{"key":"R142-6-20230208","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.3945\/ajcn.2009.28285","article-title":"Effect of high-normal compared with low-normal arterial pH on protein balances in automated peritoneal dialysis patients.","volume":"90","author":"Mehrotra","year":"2009","journal-title":"Am J Clin Nutr"},{"key":"R143-6-20230208","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1053\/j.ajkd.2005.03.003","article-title":"Metabolic acidosis of CKD: Diagnosis, clinical characteristics, and treatment.","volume":"45","author":"Kraut","year":"2005","journal-title":"Am J Kidney Dis"},{"key":"R144-6-20230208","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1093\/ndt\/gfh096","article-title":"Correction of metabolic acidosis improves thyroid and growth hormone axes in haemodialysis patients.","volume":"19","author":"Wiederkehr","year":"2004","journal-title":"Nephrol Dial Transplant"},{"key":"R145-6-20230208","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1111\/j.1523-1755.2005.09503.x","article-title":"Risks of chronic metabolic acidosis in patients with chronic kidney disease.","volume":"95","author":"Kopple","year":"2005","journal-title":"Kidney Int Suppl"},{"key":"R146-6-20230208","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1007\/s00198-006-0133-y","article-title":"Impaired muscle strength is associated with fractures in hemodialysis patients.","volume":"17","author":"Jamal","year":"2006","journal-title":"Osteoporos Int"},{"key":"R147-6-20230208","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1440-1797.2009.01261.x","article-title":"Investigation of skeletal muscle quantity and quality in end-stage renal disease.","volume":"15","author":"Cheema","year":"2010","journal-title":"Nephrology (Carlton"},{"key":"R148-6-20230208","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1046\/j.1523-1755.2003.00704.x","article-title":"Muscle atrophy in patients receiving hemodialysis: Effects on muscle strength, muscle quality, and physical function.","volume":"63","author":"Johansen","year":"2003","journal-title":"Kidney Int"},{"key":"R149-6-20230208","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1053\/j.ajkd.2010.08.021","article-title":"Baseline physical performance, health, and functioning of participants in the Frequent Hemodialysis Network (FHN) trial.","volume":"57","author":"Kaysen","year":"2011","journal-title":"Am J Kidney Dis"},{"key":"R150-6-20230208","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1080\/00365590500199319","article-title":"Elderly patients on haemodialysis have 50% less functional capacity than gender- and age-matched healthy subjects.","volume":"39","author":"Sterky","year":"2005","journal-title":"Scand J Urol Nephrol"},{"key":"R151-6-20230208","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1097\/psy.0b013e318068de1d","article-title":"Frailty is associated with incident Alzheimer\u2019s disease and cognitive decline in the elderly.","volume":"69","author":"Buchman","year":"2007","journal-title":"Psychosom Med"},{"key":"R152-6-20230208","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1093\/gerona\/glp159","article-title":"Dynapenic-obesity and physical function in older adults.","volume":"65","author":"Bouchard","year":"2010","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R153-6-20230208","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1093\/gerona\/62.12.1382","article-title":"Fat mass but not fat-free mass is related to physical capacity in well-functioning older individuals: Nutrition as a determinant of successful aging (NuAge)\u2014the Quebec Longitudinal Study.","volume":"62","author":"Bouchard","year":"2007","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R154-6-20230208","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s00421-007-0613-6","article-title":"Identification of elderly fallers by muscle strength measures.","volume":"102","author":"Pijnappels","year":"2008","journal-title":"Eur J Appl Physiol"},{"key":"R155-6-20230208","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/s11255-005-0396-9","article-title":"Prevalence of falls among seniors maintained on hemodialysis.","volume":"37","author":"Cook","year":"2005","journal-title":"Int Urol Nephrol"},{"key":"R156-6-20230208","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.2215\/CJN.01650506","article-title":"Falls and fall-related injuries in older dialysis patients.","volume":"1","author":"Cook","year":"2006","journal-title":"Clin J Am Soc Nephrol"},{"key":"R157-6-20230208","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1053\/j.ajkd.2004.09.027","article-title":"Falls in hemodialysis patients: Prospective study of incidence, risk factors, and complications.","volume":"45","author":"Desmet","year":"2005","journal-title":"Am J Kidney Dis"},{"key":"R158-6-20230208","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1093\/ndt\/gfm778","article-title":"Geriatric comorbidities, such as falls, confer an independent mortality risk to elderly dialysis patients.","volume":"23","author":"Li","year":"2008","journal-title":"Nephrol Dial Transplant"},{"key":"R159-6-20230208","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1053\/j.ajkd.2005.09.024","article-title":"PTH and the risks for hip, vertebral, and pelvic fractures among patients on dialysis.","volume":"47","author":"Danese","year":"2006","journal-title":"Am J Kidney Dis"},{"key":"R160-6-20230208","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1053\/j.jrn.2004.09.020","article-title":"Causes and consequences of the reverse epidemiology of body mass index in dialysis patients.","volume":"15","author":"Kalantar-Zadeh","year":"2005","journal-title":"J Ren Nutr"},{"key":"R161-6-20230208","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1093\/ndt\/gfp168","article-title":"Is there any survival advantage of obesity in Southern European haemodialysis patients?","volume":"24","author":"Chazot","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"R162-6-20230208","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1046\/j.1523-1755.2003.00803.x","article-title":"Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients.","volume":"63","author":"Kalantar-Zadeh","year":"2003","journal-title":"Kidney Int"},{"key":"R163-6-20230208","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1097\/01.ASN.0000083905.72794.E6","article-title":"Effects of body size and body composition on survival in hemodialysis patients.","volume":"14","author":"Beddhu","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"R164-6-20230208","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1177\/089686080502500510","article-title":"Effect of body size and body composition on survival in peritoneal dialysis patients.","volume":"25","author":"Ramkumar","year":"2005","journal-title":"Perit Dial Int"},{"key":"R165-6-20230208","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/ajcn\/81.3.543","article-title":"Survival advantages of obesity in dialysis patients.","volume":"81","author":"Kalantar-Zadeh","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"R166-6-20230208","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1159\/000095319","article-title":"Obesity paradox in patients on maintenance dialysis.","volume":"151","author":"Kalantar-Zadeh","year":"2006","journal-title":"Contrib Nephrol"},{"key":"R167-6-20230208","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1093\/ajcn\/83.2.202","article-title":"Associations of body fat and its changes over time with quality of life and prospective mortality in hemodialysis patients.","volume":"83","author":"Kalantar-Zadeh","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"R168-6-20230208","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.3109\/0886022X.2010.510233","article-title":"Influence of protein intake and muscle mass on survival in chronic dialysis patients.","volume":"32","author":"Antunes","year":"2010","journal-title":"Ren Fail"},{"key":"R169-6-20230208","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1093\/ajcn\/86.3.633","article-title":"Obese sarcopenia in patients with end-stage renal disease is associated with inflammation and increased mortality.","volume":"86","author":"Honda","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"R170-6-20230208","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1093\/ndt\/gfp492","article-title":"Abdominal fat deposition is associated with increased inflammation, protein-energy wasting and worse outcome in patients undergoing haemodialysis.","volume":"25","author":"Cordeiro","year":"2010","journal-title":"Nephrol Dial Transplant"},{"key":"R172-6-20230208","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0272-6386(96)90465-5","article-title":"Impact of the initial levels of laboratory variables on survival in chronic dialysis patients.","volume":"28","author":"Iseki","year":"1996","journal-title":"Am J Kidney Dis"},{"key":"R173-6-20230208","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1046\/j.1523-1755.1999.00768.x","article-title":"Rise in serum albumin and creatinine in the first half year on hemodialysis.","volume":"56","author":"Goldwasser","year":"1999","journal-title":"Kidney Int"},{"key":"R174-6-20230208","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1053\/ajkd.2002.33922","article-title":"Improvement of nutritional status after initiation of maintenance hemodialysis.","volume":"40","author":"Mehrotra","year":"2002","journal-title":"Am J Kidney Dis"},{"key":"R175-6-20230208","doi-asserted-by":"crossref","first-page":"S112","DOI":"10.1053\/ajkd.2003.50098","article-title":"Nutrition in daily hemodialysis.","volume":"41","author":"Schulman","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"R176-6-20230208","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/ki.2011.341","article-title":"Antioxidant therapy in hemodialysis patients: A systematic review.","volume":"81","author":"Coombes","year":"2011","journal-title":"Kidney Int"},{"key":"R177-6-20230208","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1530\/eje.1.02134","article-title":"Peroxisome proliferator-activated receptor gamma agonists in renal disease.","volume":"154","author":"Iglesias","year":"2006","journal-title":"Eur J Endocrinol"},{"key":"R178-6-20230208","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1177\/089686080702700313","article-title":"Anti-inflammatory effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors (statins) in peritoneal dialysis patients.","volume":"27","author":"Kumar","year":"2007","journal-title":"Perit Dial Int"},{"key":"R179-6-20230208","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1016\/S0140-6736(00)02783-5","article-title":"Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): Randomised placebo-controlled trial.","volume":"356","author":"Boaz","year":"2000","journal-title":"Lancet"},{"key":"R180-6-20230208","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1161\/01.CIR.0000050628.11305.30","article-title":"The antioxidant acetylcysteine reduces cardiovascular events in patients with end-stage renal failure: A randomized, controlled trial.","volume":"107","author":"Tepel","year":"2003","journal-title":"Circulation"},{"key":"R182-6-20230208","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/j.1525-139X.2010.00753.x","article-title":"Dietary protein intake in patients with advanced chronic kidney disease and on dialysis.","volume":"23","author":"Dukkipati","year":"2010","journal-title":"Semin Dial"},{"key":"R183-6-20230208","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1111\/j.1525-139X.2010.00745.x","article-title":"Epidemiology of dietary nutrient intake in ESRD.","volume":"23","author":"Kovesdy","year":"2010","journal-title":"Semin Dial"},{"key":"R184-6-20230208","doi-asserted-by":"crossref","first-page":"1562S","DOI":"10.1093\/ajcn\/87.5.1562S","article-title":"Role of dietary protein in the sarcopenia of aging.","volume":"87","author":"Paddon-Jones","year":"2008","journal-title":"Am J Clin Nutr"},{"key":"R185-6-20230208","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1093\/ajcn\/78.2.250","article-title":"Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults.","volume":"78","author":"Volpi","year":"2003","journal-title":"Am J Clin Nutr"},{"key":"R186-6-20230208","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1113\/jphysiol.2006.110742","article-title":"Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia.","volume":"575","author":"Rieu","year":"2006","journal-title":"J Physiol"},{"key":"R187-6-20230208","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1097\/MCO.0b013e32831cef8b","article-title":"Dietary protein recommendations and the prevention of sarcopenia.","volume":"12","author":"Paddon-Jones","year":"2009","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"R188-6-20230208","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1053\/j.ajkd.2005.04.036","article-title":"Multinutrient oral supplements and tube feeding in maintenance dialysis: A systematic review and meta-analysis.","volume":"46","author":"Stratton","year":"2005","journal-title":"Am J Kidney Dis"},{"key":"R189-6-20230208","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1172\/JCI0215449","article-title":"Intradialytic parenteral nutrition improves protein and energy homeostasis in chronic hemodialysis patients.","volume":"110","author":"Pupim","year":"2002","journal-title":"J Clin Invest"},{"key":"R190-6-20230208","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1097\/MNH.0b013e328331489d","article-title":"New insights into the role of anabolic interventions in dialysis patients with protein energy wasting.","volume":"18","author":"Dong","year":"2009","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"R191-6-20230208","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1053\/j.ajkd.2009.08.006","article-title":"Is there a role for intradialytic parenteral nutrition? A review of the evidence.","volume":"55","author":"Dukkipati","year":"2010","journal-title":"Am J Kidney Dis"},{"key":"R193-6-20230208","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1097\/01.ASN.0000080316.37254.7A","article-title":"Oral sodium bicarbonate for the treatment of metabolic acidosis in peritoneal dialysis patients: A randomized placebo-control trial.","volume":"14","author":"Szeto","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"R194-6-20230208","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1681\/ASN.2008111205","article-title":"Bicarbonate supplementation slows progression of CKD and improves nutritional status.","volume":"20","author":"de Brito-Ashurst","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"R195-6-20230208","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1053\/j.ajkd.2009.02.014","article-title":"Serum bicarbonate levels and the progression of kidney disease: A cohort study.","volume":"54","author":"Shah","year":"2009","journal-title":"Am J Kidney Dis"},{"key":"R196-6-20230208","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/ki.2009.519","article-title":"Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and kidney injury, and better preserved GFR.","volume":"77","author":"Phisitkul","year":"2010","journal-title":"Kidney Int"},{"key":"R197-6-20230208","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1111\/j.1523-1755.2004.00496.x","article-title":"Calcium citrate ameliorates the progression of chronic renal injury.","volume":"65","author":"Gadola","year":"2004","journal-title":"Kidney Int"},{"key":"R198-6-20230208","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/S0140-6736(58)92310-9","article-title":"Anabolic steroids in treatment of uraemia.","volume":"2","author":"Gjorup","year":"1958","journal-title":"Lancet"},{"key":"R199-6-20230208","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1532-5415.1966.tb05293.x","article-title":"Chronic renal insufficiency treated with anabolic steroids: Effects on acid-base balance, protein metabolism and hematopoiesis.","volume":"14","author":"Snyder","year":"1966","journal-title":"J Am Geriatr Soc"},{"key":"R200-6-20230208","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1159\/000180135","article-title":"Influence of anabolic steroids on nitrogen balance in chronic peritoneal dialysis.","volume":"9","author":"Lindner","year":"1972","journal-title":"Nephron"},{"key":"R201-6-20230208","first-page":"255","article-title":"Nitrogen balance in patients on maintenance peritoneal dialysis.","volume":"16","author":"Lindner","year":"1970","journal-title":"Trans Am Soc Artif Intern Organs"},{"key":"R202-6-20230208","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1001\/jama.281.14.1275","article-title":"Anabolic effects of nandrolone decanoate in patients receiving dialysis: A randomized controlled trial.","volume":"281","author":"Johansen","year":"1999","journal-title":"JAMA"},{"key":"R203-6-20230208","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/j.0894-0959.2004.17307.x","article-title":"Testosterone metabolism and replacement therapy in patients with end-stage renal disease.","volume":"17","author":"Johansen","year":"2004","journal-title":"Semin Dial"},{"key":"R204-6-20230208","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1111\/j.1532-5415.2006.00938.x","article-title":"Androgen treatment and muscle strength in elderly men: A meta-analysis.","volume":"54","author":"Ottenbacher","year":"2006","journal-title":"J Am Geriatr Soc"},{"key":"R205-6-20230208","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1681\/ASN.2006010034","article-title":"Effects of resistance exercise training and nandrolone decanoate on body composition and muscle function among patients who receive hemodialysis: A randomized, controlled trial.","volume":"17","author":"Johansen","year":"2006","journal-title":"J Am Soc Nephrol"},{"key":"R206-6-20230208","first-page":"264A","article-title":"Effect of L-carnitine on nitrogen balance in CAPD patient.","volume":"10","author":"Kopple","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"R207-6-20230208","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1172\/JCI119139","article-title":"Effects of recombinant human growth hormone on muscle protein turnover in malnourished hemodialysis patients.","volume":"99","author":"Garibotto","year":"1997","journal-title":"J Clin Invest"},{"key":"R208-6-20230208","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1681\/ASN.V261130","article-title":"Effects of recombinant human growth hormone in adults receiving maintenance hemodialysis.","volume":"2","author":"Ziegler","year":"1991","journal-title":"J Am Soc Nephrol"},{"key":"R209-6-20230208","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0272-6386(12)80399-4","article-title":"The effects of recombinant human growth hormone and intradialytic parenteral nutrition in malnourished hemodialysis patients.","volume":"21","author":"Schulman","year":"1993","journal-title":"Am J Kidney Dis"},{"key":"R210-6-20230208","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1093\/ndt\/gfh731","article-title":"Growth hormone induces anabolism in malnourished maintenance haemodialysis patients.","volume":"20","author":"Kopple","year":"2005","journal-title":"Nephrol Dial Transplant"},{"key":"R211-6-20230208","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1210\/jc.2008-2262","article-title":"Short-term administration of a combination of recombinant growth hormone and insulin-like growth factor-I induces anabolism in maintenance hemodialysis.","volume":"94","author":"Guebre-Egziabher","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"R212-6-20230208","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1681\/ASN.2006111207","article-title":"Growth hormone treatment during hemodialysis in a randomized trial improves nutrition, quality of life, and cardiovascular risk.","volume":"18","author":"Feldt-Rasmussen","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"R213-6-20230208","first-page":"99","article-title":"Influence of growth hormone on whole body and regional soft tissue composition in adult patients on hemodialysis. A double-blind, randomized, placebo-controlled study.","volume":"53","author":"Hansen","year":"2000","journal-title":"Clin Nephrol"},{"key":"R214-6-20230208","doi-asserted-by":"crossref","first-page":"4095","DOI":"10.1093\/ndt\/gfr363","article-title":"OPPORTUNITY™: A large-scale randomized clinical trial of growth hormone in hemodialysis patients.","volume":"26","author":"Kopple","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"R215-6-20230208","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1111\/j.1365-2265.2007.02962.x","article-title":"Pharmacokinetics and pharmacodynamics of growth hormone in patients on chronic haemodialysis compared with matched healthy subjects: An open, nonrandomized, parallel-group trial.","volume":"67","author":"Langbakke","year":"2007","journal-title":"Clin Endocrinol (Oxf"},{"key":"R216-6-20230208","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1046\/j.1523-1755.2001.00971.x","article-title":"Differential effects of growth hormone therapy in malnourished hemodialysis patients.","volume":"60","author":"Kotzmann","year":"2001","journal-title":"Kidney Int"},{"key":"R217-6-20230208","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0272-6386(99)70223-4","article-title":"Double-blind, placebo-controlled study of growth hormone treatment in elderly patients undergoing chronic hemodialysis: Anabolic effect and functional improvement.","volume":"33","author":"Johannsson","year":"1999","journal-title":"Am J Kidney Dis"},{"key":"R218-6-20230208","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1177\/089686089501500307","article-title":"Growth hormone and malnutrition in dialysis patients.","volume":"15","author":"Blake","year":"1995","journal-title":"Perit Dial Int"},{"key":"R219-6-20230208","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1523\/JNEUROSCI.23-04-01351.2003","article-title":"Target-derived trophic effect on skeletal muscle innervation in senescent mice.","volume":"23","author":"Messi","year":"2003","journal-title":"J Neurosci"},{"key":"R220-6-20230208","doi-asserted-by":"crossref","first-page":"C161","DOI":"10.1152\/ajpcell.00399.2007","article-title":"Muscle-specific overexpression of IGF-I improves E-C coupling in skeletal muscle fibers from dystrophic mdx mice.","volume":"294","author":"Schertzer","year":"2008","journal-title":"Am J Physiol Cell Physiol"},{"key":"R221-6-20230208","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1046\/j.1523-1755.2000.00886.x","article-title":"Recombinant human insulin-like growth factor-1 induces an anabolic response in malnourished CAPD patients.","volume":"57","author":"Fouque","year":"2000","journal-title":"Kidney Int"},{"key":"R222-6-20230208","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1177\/0148607195019003231","article-title":"Altered mental function during intravenous infusion of recombinant human insulin-like growth factor 1.","volume":"19","author":"Fouque","year":"1995","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"R223-6-20230208","first-page":"F917","article-title":"Effects of IGF-I on renal function in patients with chronic renal failure.","volume":"264","author":"O\u2019Shea","year":"1993","journal-title":"Am J Physiol"},{"key":"R224-6-20230208","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1053\/j.jrn.2004.09.022","article-title":"Impaired exercise capacity and exercise training in maintenance hemodialysis patients.","volume":"15","author":"Kopple","year":"2005","journal-title":"J Ren Nutr"},{"key":"R225-6-20230208","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1053\/ajkd.2000.16200","article-title":"Low-functioning hemodialysis patients improve with exercise training.","volume":"36","author":"Painter","year":"2000","journal-title":"Am J Kidney Dis"},{"key":"R226-6-20230208","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1053\/j.ajkd.2003.12.025","article-title":"Resistance training to reduce the malnutrition-inflammation complex syndrome of chronic kidney disease.","volume":"43","author":"Castaneda","year":"2004","journal-title":"Am J Kidney Dis"},{"key":"R227-6-20230208","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1681\/ASN.2006121329","article-title":"Progressive exercise for anabolism in kidney disease (PEAK): A randomized, controlled trial of resistance training during hemodialysis.","volume":"18","author":"Cheema","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"R228-6-20230208","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1159\/000045959","article-title":"Twelve weeks of exercise training increases muscle function and walking capacity in elderly predialysis patients and healthy subjects.","volume":"88","author":"Heiwe","year":"2001","journal-title":"Nephron"},{"key":"R229-6-20230208","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1093\/ndt\/gfp739","article-title":"Effect of intra-dialytic, low-intensity strength training on functional capacity in adult haemodialysis patients: A randomized pilot trial.","volume":"25","author":"Chen","year":"2010","journal-title":"Nephrol Dial Transplant"}],"container-title":["Journal of the American Society of Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00001751-201303000-00006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T19:22:26Z","timestamp":1786130546000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00001751-201303000-00006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":224,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1681\/asn.2012010047","relation":{},"ISSN":["1046-6673"],"issn-type":[{"value":"1046-6673","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]}}}