{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T21:55:14Z","timestamp":1792446914900,"version":"4.5.0"},"reference-count":171,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1681\/asn.2014030262","type":"journal-article","created":{"date-parts":[[2014,6,13]],"date-time":"2014-06-13T03:51:31Z","timestamp":1402631491000},"page":"2689-2701","source":"Crossref","is-referenced-by-count":541,"title":["Regulated Cell Death in AKI"],"prefix":"10.1681","volume":"25","author":[{"given":"Andreas","family":"Linkermann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guochun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guie","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Kunzendorf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Krautwald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-6-20230306","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/S0140-6736(13)60647-9","article-title":"Acute kidney injury: An increasing global concern.","volume":"382","author":"Lameire","year":"2013","journal-title":"Lancet"},{"key":"R2-6-20230306","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1681\/ASN.2012080800","article-title":"Temporal changes in incidence of dialysis-requiring AKI.","volume":"24","author":"Hsu","year":"2013","journal-title":"J Am Soc Nephrol"},{"key":"R3-6-20230306","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1681\/ASN.2012030222","article-title":"Yes, AKI truly leads to CKD.","volume":"23","author":"Hsu","year":"2012","journal-title":"J Am Soc Nephrol"},{"key":"R4-6-20230306","doi-asserted-by":"crossref","first-page":"861","DOI":"10.2215\/CJN.12191111","article-title":"Ongoing clinical trials in AKI.","volume":"7","author":"Faubel","year":"2012","journal-title":"Clin J Am Soc Nephrol"},{"key":"R5-6-20230306","doi-asserted-by":"crossref","first-page":"4210","DOI":"10.1172\/JCI45161","article-title":"Cellular pathophysiology of ischemic acute kidney injury.","volume":"121","author":"Bonventre","year":"2011","journal-title":"J Clin Invest"},{"key":"R6-6-20230306","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1681\/ASN.2013050502","article-title":"Regulatory T cells in AKI.","volume":"24","author":"Kinsey","year":"2013","journal-title":"J Am Soc Nephrol"},{"key":"R7-6-20230306","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/nrneph.2011.16","article-title":"Pathophysiology of ischemic acute kidney injury.","volume":"7","author":"Sharfuddin","year":"2011","journal-title":"Nat Rev Nephrol"},{"key":"R8-6-20230306","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1681\/ASN.2010050484","article-title":"Sepsis and acute kidney injury.","volume":"22","author":"Zarjou","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"R9-6-20230306","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1681\/ASN.2012060633","article-title":"Messengers without borders: Mediators of systemic inflammatory response in AKI.","volume":"24","author":"Ratliff","year":"2013","journal-title":"J Am Soc Nephrol"},{"key":"R10-6-20230306","first-page":"831","article-title":"Morphologic, biochemical, and molecular evidence of apoptosis during the reperfusion phase after brief periods of renal ischemia.","volume":"140","author":"Schumer","year":"1992","journal-title":"Am J Pathol"},{"key":"R11-6-20230306","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/01.ASN.0000040596.23073.01","article-title":"P53 mediates the apoptotic response to GTP depletion after renal ischemia-reperfusion: Protective role of a p53 inhibitor.","volume":"14","author":"Kelly","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"R12-6-20230306","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1172\/JCI13018","article-title":"Guanosine supplementation reduces apoptosis and protects renal function in the setting of ischemic injury.","volume":"108","author":"Kelly","year":"2001","journal-title":"J Clin Invest"},{"key":"R13-6-20230306","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1681\/ASN.V1341000","article-title":"DNase I-like endonuclease in rat kidney cortex that is activated during ischemia\/reperfusion injury.","volume":"13","author":"Basnakian","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"R14-6-20230306","first-page":"F587","article-title":"Identification of gene family of caspases in rat kidney and altered expression in ischemia-reperfusion injury.","volume":"274","author":"Kaushal","year":"1998","journal-title":"Am J Physiol"},{"key":"R15-6-20230306","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1681\/ASN.V113454","article-title":"Relationship between expression of Bcl-2 genes and growth factors in ischemic acute renal failure in the rat.","volume":"11","author":"Gob\u00e9","year":"2000","journal-title":"J Am Soc Nephrol"},{"key":"R16-6-20230306","first-page":"F640","article-title":"Expression of bcl-2 and bax in regenerating rat renal tubules following ischemic injury.","volume":"272","author":"Basile","year":"1997","journal-title":"Am J Physiol"},{"key":"R17-6-20230306","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.3390\/toxins2112490","article-title":"Mechanisms of Cisplatin nephrotoxicity.","volume":"2","author":"Miller","year":"2010","journal-title":"Toxins (Basel"},{"key":"R18-6-20230306","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1038\/sj.ki.5002786","article-title":"Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies.","volume":"73","author":"Pabla","year":"2008","journal-title":"Kidney Int"},{"key":"R19-6-20230306","doi-asserted-by":"crossref","first-page":"F990","DOI":"10.1152\/ajprenal.00206.2004","article-title":"PPAR-alpha ligand ameliorates acute renal failure by reducing cisplatin-induced increased expression of renal endonuclease G.","volume":"287","author":"Li","year":"2004","journal-title":"Am J Physiol Renal Physiol"},{"key":"R20-6-20230306","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1046\/j.1523-1755.2003.00908.x","article-title":"Cytochrome P450 2E1 null mice provide novel protection against cisplatin-induced nephrotoxicity and apoptosis.","volume":"63","author":"Liu","year":"2003","journal-title":"Kidney Int"},{"key":"R21-6-20230306","doi-asserted-by":"crossref","first-page":"2709","DOI":"10.1172\/JCI45586","article-title":"Inhibition of PKC\u03b4 reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer.","volume":"121","author":"Pabla","year":"2011","journal-title":"J Clin Invest"},{"key":"R22-6-20230306","doi-asserted-by":"crossref","first-page":"F166","DOI":"10.1152\/ajprenal.00401.2004","article-title":"p38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice.","volume":"289","author":"Ramesh","year":"2005","journal-title":"Am J Physiol Renal Physiol"},{"key":"R23-6-20230306","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s00204-003-0521-4","article-title":"Cellular and molecular studies on cisplatin-induced apoptotic cell death in rat kidney.","volume":"78","author":"Sheikh-Hamad","year":"2004","journal-title":"Arch Toxicol"},{"key":"R24-6-20230306","doi-asserted-by":"crossref","first-page":"F726","DOI":"10.1152\/ajprenal.2000.278.5.F726","article-title":"Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis.","volume":"278","author":"Shiraishi","year":"2000","journal-title":"Am J Physiol Renal Physiol"},{"key":"R25-6-20230306","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s00134-009-1723-x","article-title":"Histopathology of septic shock induced acute kidney injury: Apoptosis and leukocytic infiltration.","volume":"36","author":"Lerolle","year":"2010","journal-title":"Intensive Care Med"},{"key":"R26-6-20230306","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/ki.2011.120","article-title":"Apoptosis and acute kidney injury.","volume":"80","author":"Havasi","year":"2011","journal-title":"Kidney Int"},{"key":"R27-6-20230306","doi-asserted-by":"crossref","first-page":"12024","DOI":"10.1073\/pnas.1305538110","article-title":"Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury.","volume":"110","author":"Linkermann","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R28-6-20230306","doi-asserted-by":"crossref","first-page":"19948","DOI":"10.1074\/jbc.M313629200","article-title":"Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria.","volume":"279","author":"Wang","year":"2004","journal-title":"J Biol Chem"},{"key":"R29-6-20230306","doi-asserted-by":"crossref","first-page":"F35","DOI":"10.1152\/ajprenal.00184.2005","article-title":"Bid deficiency ameliorates ischemic renal failure and delays animal death in C57BL\/6 mice.","volume":"290","author":"Wei","year":"2006","journal-title":"Am J Physiol Renal Physiol"},{"key":"R30-6-20230306","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1159\/000088171","article-title":"Differential gender differences in ischemic and nephrotoxic acute renal failure.","volume":"25","author":"Wei","year":"2005","journal-title":"Am J Nephrol"},{"key":"R31-6-20230306","doi-asserted-by":"crossref","first-page":"4056","DOI":"10.1038\/sj.onc.1209440","article-title":"Regulation of PUMA-alpha by p53 in cisplatin-induced renal cell apoptosis.","volume":"25","author":"Jiang","year":"2006","journal-title":"Oncogene"},{"key":"R32-6-20230306","doi-asserted-by":"crossref","first-page":"3451","DOI":"10.1172\/JCI25461","article-title":"Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney ischemia.","volume":"115","author":"Thakar","year":"2005","journal-title":"J Clin Invest"},{"key":"R33-6-20230306","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1097\/01.ASN.0000138287.46849.82","article-title":"Blockade of calcium influx through L-type calcium channels attenuates mitochondrial injury and apoptosis in hypoxic renal tubular cells.","volume":"15","author":"Tanaka","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"R34-6-20230306","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1097\/01.ASN.0000135059.67385.5D","article-title":"Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion.","volume":"15","author":"Sharples","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"R35-6-20230306","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1097\/01.ASN.0000102474.68613.AE","article-title":"A1 adenosine receptor activation inhibits inflammation, necrosis, and apoptosis after renal ischemia-reperfusion injury in mice.","volume":"15","author":"Lee","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"R36-6-20230306","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1172\/JCI20921","article-title":"The renal papilla is a niche for adult kidney stem cells.","volume":"114","author":"Oliver","year":"2004","journal-title":"J Clin Invest"},{"key":"R37-6-20230306","doi-asserted-by":"crossref","first-page":"F760","DOI":"10.1152\/ajprenal.00050.2004","article-title":"Minocycline inhibits apoptosis and inflammation in a rat model of ischemic renal injury.","volume":"287","author":"Kelly","year":"2004","journal-title":"Am J Physiol Renal Physiol"},{"key":"R38-6-20230306","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/ki.2012.471","article-title":"The authors reply.","volume":"83","author":"Linkermann","year":"2013","journal-title":"Kidney Int"},{"key":"R39-6-20230306","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1038\/ki.2013.68","article-title":"Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule-specific knockout mouse models.","volume":"84","author":"Wei","year":"2013","journal-title":"Kidney Int"},{"key":"R40-6-20230306","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1126\/science.281.5381.1305","article-title":"Death receptors: Signaling and modulation.","volume":"281","author":"Ashkenazi","year":"1998","journal-title":"Science"},{"key":"R41-6-20230306","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1038\/47513","article-title":"Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta.","volume":"403","author":"Nakagawa","year":"2000","journal-title":"Nature"},{"key":"R42-6-20230306","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1126\/science.1074721","article-title":"Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization.","volume":"297","author":"Lassus","year":"2002","journal-title":"Science"},{"key":"R43-6-20230306","doi-asserted-by":"crossref","first-page":"5817","DOI":"10.4049\/jimmunol.168.11.5817","article-title":"Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney.","volume":"168","author":"Cunningham","year":"2002","journal-title":"J Immunol"},{"key":"R44-6-20230306","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1046\/j.1523-1755.2001.00740.x","article-title":"Endotoxemic renal failure in mice: Role of tumor necrosis factor independent of inducible nitric oxide synthase.","volume":"59","author":"Knotek","year":"2001","journal-title":"Kidney Int"},{"key":"R45-6-20230306","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1093\/ndt\/14.8.1831","article-title":"The Fas ligand\/Fas system in renal injury.","volume":"14","author":"Ortiz","year":"1999","journal-title":"Nephrol Dial Transplant"},{"key":"R46-6-20230306","doi-asserted-by":"crossref","first-page":"S56","DOI":"10.1111\/j.1523-1755.2004.09109.x","article-title":"Inflammatory cytokines in acute renal failure.","volume":"91","author":"Ramesh","year":"2004","journal-title":"Kidney Int Suppl"},{"key":"R47-6-20230306","doi-asserted-by":"crossref","first-page":"31230","DOI":"10.1074\/jbc.M503305200","article-title":"p53-dependent caspase-2 activation in mitochondrial release of apoptosis-inducing factor and its role in renal tubular epithelial cell injury.","volume":"280","author":"Seth","year":"2005","journal-title":"J Biol Chem"},{"key":"R48-6-20230306","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1681\/ASN.2004090768","article-title":"Endoplasmic reticulum stress-associated caspase 12 mediates cisplatin-induced LLC-PK1 cell apoptosis.","volume":"16","author":"Liu","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"R49-6-20230306","doi-asserted-by":"crossref","first-page":"3401","DOI":"10.1038\/sj.onc.1202590","article-title":"Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury.","volume":"17","author":"Saikumar","year":"1998","journal-title":"Oncogene"},{"key":"R50-6-20230306","doi-asserted-by":"crossref","first-page":"18361","DOI":"10.1074\/jbc.M100655200","article-title":"Bcl-2 prevents Bax oligomerization in the mitochondrial outer membrane.","volume":"276","author":"Mikhailov","year":"2001","journal-title":"J Biol Chem"},{"key":"R51-6-20230306","doi-asserted-by":"crossref","first-page":"5367","DOI":"10.1074\/jbc.M203392200","article-title":"Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release.","volume":"278","author":"Mikhailov","year":"2003","journal-title":"J Biol Chem"},{"key":"R52-6-20230306","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1093\/gerona\/60.7.830","article-title":"Mitochondrial pathway is responsible for aging-related increase of tubular cell apoptosis in renal ischemia\/reperfusion injury.","volume":"60","author":"Qiao","year":"2005","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R53-6-20230306","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/j.1600-6143.2004.00657.x","article-title":"Apoptotic cell death is initiated during normothermic ischemia in human kidneys.","volume":"5","author":"Wolfs","year":"2005","journal-title":"Am J Transplant"},{"key":"R54-6-20230306","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/01.TP.0000069835.95442.9F","article-title":"Activation of mitochondrial apoptotic pathways in human renal allografts after ischemiareperfusion injury.","volume":"76","author":"Castaneda","year":"2003","journal-title":"Transplantation"},{"key":"R55-6-20230306","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0092-8674(00)81589-5","article-title":"Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors.","volume":"94","author":"Luo","year":"1998","journal-title":"Cell"},{"key":"R56-6-20230306","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S0092-8674(00)81590-1","article-title":"Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis.","volume":"94","author":"Li","year":"1998","journal-title":"Cell"},{"key":"R57-6-20230306","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/sj.embor.7400375","article-title":"Proapoptotic BAX and BAK control multiple initiator caspases.","volume":"6","author":"Ruiz-Vela","year":"2005","journal-title":"EMBO Rep"},{"key":"R58-6-20230306","doi-asserted-by":"crossref","first-page":"38271","DOI":"10.1074\/jbc.M506488200","article-title":"Essential roles of the Bcl-2 family of proteins in caspase-2-induced apoptosis.","volume":"280","author":"Gao","year":"2005","journal-title":"J Biol Chem"},{"key":"R59-6-20230306","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/35048069","article-title":"Breaking the mitochondrial barrier.","volume":"2","author":"Martinou","year":"2001","journal-title":"Nat Rev Mol Cell Biol"},{"key":"R60-6-20230306","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/74994","article-title":"Mitochondrial control of cell death.","volume":"6","author":"Kroemer","year":"2000","journal-title":"Nat Med"},{"key":"R61-6-20230306","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/nrm2308","article-title":"The BCL-2 protein family: Opposing activities that mediate cell death.","volume":"9","author":"Youle","year":"2008","journal-title":"Nat Rev Mol Cell Biol"},{"key":"R62-6-20230306","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0092-8674(04)00046-7","article-title":"Cell death: Critical control points.","volume":"116","author":"Danial","year":"2004","journal-title":"Cell"},{"key":"R63-6-20230306","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1126\/science.281.5381.1322","article-title":"The Bcl-2 protein family: Arbiters of cell survival.","volume":"281","author":"Adams","year":"1998","journal-title":"Science"},{"key":"R64-6-20230306","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1126\/science.1059108","article-title":"Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death.","volume":"292","author":"Wei","year":"2001","journal-title":"Science"},{"key":"R65-6-20230306","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/sj.ki.5002256","article-title":"The pathological role of Bax in cisplatin nephrotoxicity.","volume":"72","author":"Wei","year":"2007","journal-title":"Kidney Int"},{"key":"R66-6-20230306","doi-asserted-by":"crossref","first-page":"9369","DOI":"10.1128\/MCB.25.21.9369-9382.2005","article-title":"Loss of Bif-1 suppresses Bax\/Bak conformational change and mitochondrial apoptosis.","volume":"25","author":"Takahashi","year":"2005","journal-title":"Mol Cell Biol"},{"key":"R67-6-20230306","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1038\/ncb950","article-title":"Ku70 suppresses the apoptotic translocation of Bax to mitochondria.","volume":"5","author":"Sawada","year":"2003","journal-title":"Nat Cell Biol"},{"key":"R68-6-20230306","doi-asserted-by":"crossref","first-page":"16992","DOI":"10.1074\/jbc.M300039200","article-title":"Inhibition of Bid-induced apoptosis by Bcl-2. tBid insertion, Bax translocation, and Bax\/Bak oligomerization suppressed.","volume":"278","author":"Yi","year":"2003","journal-title":"J Biol Chem"},{"key":"R69-6-20230306","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1074\/jbc.M207880200","article-title":"14-3-3 Interacts directly with and negatively regulates pro-apoptotic Bax.","volume":"278","author":"Nomura","year":"2003","journal-title":"J Biol Chem"},{"key":"R70-6-20230306","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/nature01627","article-title":"Humanin peptide suppresses apoptosis by interfering with Bax activation.","volume":"423","author":"Guo","year":"2003","journal-title":"Nature"},{"key":"R71-6-20230306","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1128\/MCB.20.3.929-935.2000","article-title":"Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane.","volume":"20","author":"Eskes","year":"2000","journal-title":"Mol Cell Biol"},{"key":"R72-6-20230306","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1126\/science.1092734","article-title":"Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis.","volume":"303","author":"Chipuk","year":"2004","journal-title":"Science"},{"key":"R73-6-20230306","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1128\/MCB.00015-13","article-title":"Nucleophosmin, a critical Bax cofactor in ischemia-induced cell death.","volume":"33","author":"Wang","year":"2013","journal-title":"Mol Cell Biol"},{"key":"R74-6-20230306","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1126\/science.1219855","article-title":"Mitochondrial fission, fusion, and stress.","volume":"337","author":"Youle","year":"2012","journal-title":"Science"},{"key":"R75-6-20230306","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1146\/annurev-genet-110410-132529","article-title":"Fusion and fission: Interlinked processes critical for mitochondrial health.","volume":"46","author":"Chan","year":"2012","journal-title":"Annu Rev Genet"},{"key":"R76-6-20230306","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/S1534-5807(01)00055-7","article-title":"The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis.","volume":"1","author":"Frank","year":"2001","journal-title":"Dev Cell"},{"key":"R77-6-20230306","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1172\/JCI37829","article-title":"Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models.","volume":"119","author":"Brooks","year":"2009","journal-title":"J Clin Invest"},{"key":"R78-6-20230306","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1038\/cdd.2012.18","article-title":"Inhibition of Drp1 provides neuroprotection in vitro and in vivo.","volume":"19","author":"Grohm","year":"2012","journal-title":"Cell Death Differ"},{"key":"R79-6-20230306","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1161\/CIRCULATIONAHA.109.906610","article-title":"Inhibiting mitochondrial fission protects the heart against ischemia\/reperfusion injury.","volume":"121","author":"Ong","year":"2010","journal-title":"Circulation"},{"key":"R80-6-20230306","doi-asserted-by":"crossref","first-page":"F199","DOI":"10.1152\/ajprenal.00716.2009","article-title":"Drp1 dephosphorylation in ATP depletion-induced mitochondrial injury and tubular cell apoptosis.","volume":"299","author":"Cho","year":"2010","journal-title":"Am J Physiol Renal Physiol"},{"key":"R81-6-20230306","doi-asserted-by":"crossref","first-page":"11649","DOI":"10.1073\/pnas.0703976104","article-title":"Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins.","volume":"104","author":"Brooks","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R82-6-20230306","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1165\/rcmb.2008-0302OC","article-title":"IL-6 protects against hyperoxia-induced mitochondrial damage via Bcl-2-induced Bak interactions with mitofusins.","volume":"41","author":"Waxman","year":"2009","journal-title":"Am J Respir Cell Mol Biol"},{"key":"R83-6-20230306","doi-asserted-by":"crossref","first-page":"C447","DOI":"10.1152\/ajpcell.00402.2010","article-title":"Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis.","volume":"300","author":"Brooks","year":"2011","journal-title":"Am J Physiol Cell Physiol"},{"key":"R84-6-20230306","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1038\/ki.2012.441","article-title":"Mitochondrial dynamics: Regulatory mechanisms and emerging role in renal pathophysiology.","volume":"83","author":"Zhan","year":"2013","journal-title":"Kidney Int"},{"key":"R85-6-20230306","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.cmet.2012.01.009","article-title":"Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells.","volume":"15","author":"Wang","year":"2012","journal-title":"Cell Metab"},{"key":"R86-6-20230306","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.immuni.2013.02.003","article-title":"Necroptosis: The release of damage-associated molecular patterns and its physiological relevance.","volume":"38","author":"Kaczmarek","year":"2013","journal-title":"Immunity"},{"key":"R87-6-20230306","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/nri2215","article-title":"How dying cells alert the immune system to danger.","volume":"8","author":"Kono","year":"2008","journal-title":"Nat Rev Immunol"},{"key":"R88-6-20230306","doi-asserted-by":"crossref","first-page":"2797","DOI":"10.1111\/ajt.12448","article-title":"Necroptosis in immunity and ischemia-reperfusion injury.","volume":"13","author":"Linkermann","year":"2013","journal-title":"Am J Transplant"},{"key":"R90-6-20230306","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/nrm3737","article-title":"Regulated necrosis: The expanding network of non-apoptotic cell death pathways.","volume":"15","author":"Vanden Berghe","year":"2014","journal-title":"Nat Rev Mol Cell Biol"},{"key":"R91-6-20230306","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.celrep.2013.10.034","article-title":"Widespread mitochondrial depletion via mitophagy does not compromise necroptosis.","volume":"5","author":"Tait","year":"2013","journal-title":"Cell Reports"},{"key":"R92-6-20230306","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nature09857","article-title":"RIP3 mediates the embryonic lethality of caspase-8-deficient mice.","volume":"471","author":"Kaiser","year":"2011","journal-title":"Nature"},{"key":"R93-6-20230306","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/nature09852","article-title":"Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis.","volume":"471","author":"Oberst","year":"2011","journal-title":"Nature"},{"key":"R94-6-20230306","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1128\/MCB.24.4.1464-1469.2004","article-title":"Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.","volume":"24","author":"Newton","year":"2004","journal-title":"Mol Cell Biol"},{"key":"R95-6-20230306","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1038\/nrm3214","article-title":"It cuts both ways: Reconciling the dual roles of caspase 8 in cell death and survival.","volume":"12","author":"Oberst","year":"2011","journal-title":"Nat Rev Mol Cell Biol"},{"key":"R96-6-20230306","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.cell.2005.05.019","article-title":"Apoptotic pathways: Ten minutes to dead.","volume":"121","author":"Green","year":"2005","journal-title":"Cell"},{"key":"R97-6-20230306","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/nri2115","article-title":"Life and death in peripheral T cells.","volume":"7","author":"Krammer","year":"2007","journal-title":"Nat Rev Immunol"},{"key":"R98-6-20230306","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.immuni.2012.09.015","article-title":"Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome.","volume":"38","author":"Kang","year":"2013","journal-title":"Immunity"},{"key":"R99-6-20230306","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1056\/NEJMra1310050","article-title":"Necroptosis.","volume":"370","author":"Linkermann","year":"2014","journal-title":"N Engl J Med"},{"key":"R100-6-20230306","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/82732","article-title":"Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule.","volume":"1","author":"Holler","year":"2000","journal-title":"Nat Immunol"},{"key":"R101-6-20230306","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1084\/jem.187.9.1477","article-title":"Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.","volume":"187","author":"Vercammen","year":"1998","journal-title":"J Exp Med"},{"key":"R102-6-20230306","doi-asserted-by":"crossref","first-page":"31268","DOI":"10.1074\/jbc.M113.462341","article-title":"Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.","volume":"288","author":"Kaiser","year":"2013","journal-title":"J Biol Chem"},{"key":"R103-6-20230306","doi-asserted-by":"crossref","first-page":"2934","DOI":"10.1128\/MCB.05445-11","article-title":"NF-kappaB protects cells from gamma interferon-induced RIP1-dependent necroptosis.","volume":"31","author":"Thapa","year":"2011","journal-title":"Mol Cell Biol"},{"key":"R104-6-20230306","doi-asserted-by":"crossref","first-page":"E3109","DOI":"10.1073\/pnas.1301218110","article-title":"Interferon-induced RIP1\/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases.","volume":"110","author":"Thapa","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R105-6-20230306","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.chom.2010.03.006","article-title":"Virus inhibition of RIP3-dependent necrosis.","volume":"7","author":"Upton","year":"2010","journal-title":"Cell Host Microbe"},{"key":"R106-6-20230306","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.chom.2012.01.016","article-title":"DAI\/ZBP1\/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.","volume":"11","author":"Upton","year":"2012","journal-title":"Cell Host Microbe"},{"key":"R107-6-20230306","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1016\/j.cell.2009.05.037","article-title":"Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation.","volume":"137","author":"Cho","year":"2009","journal-title":"Cell"},{"key":"R108-6-20230306","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.cell.2009.05.021","article-title":"Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha.","volume":"137","author":"He","year":"2009","journal-title":"Cell"},{"key":"R109-6-20230306","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1126\/science.1172308","article-title":"RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis.","volume":"325","author":"Zhang","year":"2009","journal-title":"Science"},{"key":"R110-6-20230306","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.immuni.2013.06.018","article-title":"The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism.","volume":"39","author":"Murphy","year":"2013","journal-title":"Immunity"},{"key":"R111-6-20230306","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.cell.2011.11.031","article-title":"Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase.","volume":"148","author":"Sun","year":"2012","journal-title":"Cell"},{"key":"R112-6-20230306","doi-asserted-by":"crossref","first-page":"5322","DOI":"10.1073\/pnas.1200012109","article-title":"Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis.","volume":"109","author":"Zhao","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R113-6-20230306","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1042\/BJ20131270","article-title":"Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL.","volume":"457","author":"Murphy","year":"2014","journal-title":"Biochem J"},{"key":"R114-6-20230306","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.molcel.2014.03.003","article-title":"Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.","volume":"54","author":"Wang","year":"2014","journal-title":"Mol Cell"},{"key":"R115-6-20230306","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1038\/ki.2011.450","article-title":"Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia\/reperfusion injury.","volume":"81","author":"Linkermann","year":"2012","journal-title":"Kidney Int"},{"key":"R116-6-20230306","doi-asserted-by":"crossref","first-page":"F764","DOI":"10.1152\/ajprenal.00061.2013","article-title":"Protein kinase C-\u03b1 interaction with iHSP70 in mitochondria promotes recovery of mitochondrial function after injury in renal proximal tubular cells.","volume":"305","author":"Nowak","year":"2013","journal-title":"Am J Physiol Renal Physiol"},{"key":"R117-6-20230306","doi-asserted-by":"crossref","first-page":"373","DOI":"10.3109\/0886022X.2011.647343","article-title":"Nec-1 protects against nonapoptotic cell death in cisplatin-induced kidney injury.","volume":"34","author":"Trist\u00e3o","year":"2012","journal-title":"Ren Fail"},{"key":"R118-6-20230306","doi-asserted-by":"crossref","first-page":"24742","DOI":"10.3390\/ijms141224742","article-title":"Necrostatin-1 attenuates ischemia injury induced cell death in rat tubular cell line NRK-52E through decreased Drp1 expression.","volume":"14","author":"Zhang","year":"2013","journal-title":"Int J Mol Sci"},{"key":"R119-6-20230306","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1172\/JCI6974","article-title":"Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation.","volume":"104","author":"Daemen","year":"1999","journal-title":"J Clin Invest"},{"key":"R120-6-20230306","first-page":"725","article-title":"Necroptosis contributes to the cyclosporin A-induced cytotoxicity in NRK-52E cells.","volume":"67","author":"Ouyang","year":"2012","journal-title":"Pharmazie"},{"key":"R121-6-20230306","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1681\/ASN.2012121169","article-title":"The RIP1-kinase inhibitor necrostatin-1 prevents osmotic nephrosis and contrast-induced AKI in mice.","volume":"24","author":"Linkermann","year":"2013","journal-title":"J Am Soc Nephrol"},{"key":"R123-6-20230306","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/nri2545","article-title":"Immunogenic and tolerogenic cell death.","volume":"9","author":"Green","year":"2009","journal-title":"Nat Rev Immunol"},{"key":"R124-6-20230306","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/nrm2952","article-title":"Mitochondria and cell death: Outer membrane permeabilization and beyond.","volume":"11","author":"Tait","year":"2010","journal-title":"Nat Rev Mol Cell Biol"},{"key":"R125-6-20230306","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1152\/physrev.00013.2006","article-title":"Mitochondrial membrane permeabilization in cell death.","volume":"87","author":"Kroemer","year":"2007","journal-title":"Physiol Rev"},{"key":"R126-6-20230306","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S0006-291X(03)00618-1","article-title":"Mitochondrial permeability transition: A common pathway to necrosis and apoptosis.","volume":"304","author":"Kim","year":"2003","journal-title":"Biochem Biophys Res Commun"},{"key":"R127-6-20230306","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3389\/fphys.2013.00095","article-title":"The mitochondrial permeability transition pore: A mystery solved?","volume":"4","author":"Bernardi","year":"2013","journal-title":"Front Physiol"},{"key":"R128-6-20230306","doi-asserted-by":"crossref","first-page":"5887","DOI":"10.1073\/pnas.1217823110","article-title":"Dimers of mitochondrial ATP synthase form the permeability transition pore.","volume":"110","author":"Giorgio","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R129-6-20230306","doi-asserted-by":"crossref","first-page":"F749","DOI":"10.1152\/ajprenal.00239.2009","article-title":"Cyclophilin D gene ablation protects mice from ischemic renal injury.","volume":"297","author":"Devalaraja-Narashimha","year":"2009","journal-title":"Am J Physiol Renal Physiol"},{"key":"R130-6-20230306","doi-asserted-by":"crossref","first-page":"F134","DOI":"10.1152\/ajprenal.00033.2011","article-title":"Cyclophilin D and the mitochondrial permeability transition in kidney proximal tubules after hypoxic and ischemic injury.","volume":"301","author":"Park","year":"2011","journal-title":"Am J Physiol Renal Physiol"},{"key":"R131-6-20230306","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1038\/nrm3401","article-title":"Cell death: Multitasking p53 promotes necrosis.","volume":"13","author":"Baumann","year":"2012","journal-title":"Nat Rev Mol Cell Biol"},{"key":"R132-6-20230306","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1016\/j.cell.2012.05.014","article-title":"p53 opens the mitochondrial permeability transition pore to trigger necrosis.","volume":"149","author":"Vaseva","year":"2012","journal-title":"Cell"},{"key":"R133-6-20230306","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1161\/CIRCRESAHA.112.280990","article-title":"Is p53 the long-sought molecular trigger for cyclophilin D-regulated mitochondrial permeability transition pore formation and necrosis?","volume":"111","author":"Karch","year":"2012","journal-title":"Circ Res"},{"key":"R134-6-20230306","doi-asserted-by":"crossref","first-page":"34793","DOI":"10.1074\/jbc.M202191200","article-title":"Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A.","volume":"277","author":"Clarke","year":"2002","journal-title":"J Biol Chem"},{"key":"R135-6-20230306","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/ki.1997.313","article-title":"Glycine-protected, hypoxic, proximal tubules develop severely compromised energetic function.","volume":"52","author":"Weinberg","year":"1997","journal-title":"Kidney Int"},{"key":"R136-6-20230306","doi-asserted-by":"crossref","first-page":"F1632","DOI":"10.1152\/ajprenal.00422.2009","article-title":"Regulation of the mitochondrial permeability transition in kidney proximal tubules and its alteration during hypoxia-reoxygenation.","volume":"297","author":"Feldkamp","year":"2009","journal-title":"Am J Physiol Renal Physiol"},{"key":"R137-6-20230306","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1056\/NEJMoa071142","article-title":"Effect of cyclosporine on reperfusion injury in acute myocardial infarction.","volume":"359","author":"Piot","year":"2008","journal-title":"N Engl J Med"},{"key":"R138-6-20230306","doi-asserted-by":"crossref","first-page":"F450","DOI":"10.1152\/ajprenal.00059.2011","article-title":"Loss of poly(ADP-ribose) polymerase 1 attenuates renal fibrosis and inflammation during unilateral ureteral obstruction.","volume":"301","author":"Kim","year":"2011","journal-title":"Am J Physiol Renal Physiol"},{"key":"R139-6-20230306","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1038\/ki.2012.64","article-title":"Poly(ADP-ribose) polymerase 1 activation is required for cisplatin nephrotoxicity.","volume":"82","author":"Kim","year":"2012","journal-title":"Kidney Int"},{"key":"R140-6-20230306","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/nrmicro2070","article-title":"Pyroptosis: Host cell death and inflammation.","volume":"7","author":"Bergsbaken","year":"2009","journal-title":"Nat Rev Microbiol"},{"key":"R141-6-20230306","doi-asserted-by":"crossref","first-page":"2748","DOI":"10.4049\/jimmunol.1100477","article-title":"Coordinated host responses during pyroptosis: Caspase-1-dependent lysosome exocytosis and inflammatory cytokine maturation.","volume":"187","author":"Bergsbaken","year":"2011","journal-title":"J Immunol"},{"key":"R142-6-20230306","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/nature12940","article-title":"Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection.","volume":"505","author":"Doitsh","year":"2014","journal-title":"Nature"},{"key":"R143-6-20230306","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/jcbfm.2013.236","article-title":"Pyroptotic neuronal cell death mediated by the AIM2 inflammasome.","volume":"34","author":"Adamczak","year":"2014","journal-title":"J Cereb Blood Flow Metab"},{"key":"R144-6-20230306","doi-asserted-by":"crossref","first-page":"e47299","DOI":"10.1371\/journal.pone.0047299","article-title":"Activating Nrf-2 signaling depresses unilateral ureteral obstruction-evoked mitochondrial stress-related autophagy, apoptosis and pyroptosis in kidney.","volume":"7","author":"Chung","year":"2012","journal-title":"PLoS ONE"},{"key":"R145-6-20230306","doi-asserted-by":"crossref","first-page":"F75","DOI":"10.1152\/ajprenal.00117.2013","article-title":"Ischemia-reperfusion induces renal tubule pyroptosis via the CHOP-caspase-11 pathway.","volume":"306","author":"Yang","year":"2014","journal-title":"Am J Physiol Renal Physiol"},{"key":"R146-6-20230306","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/ndt\/gft332","article-title":"Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis.","volume":"29","author":"Lorenz","year":"2014","journal-title":"Nephrol Dial Transplant"},{"key":"R147-6-20230306","doi-asserted-by":"crossref","first-page":"F168","DOI":"10.1152\/ajprenal.00552.2013","article-title":"The fire within: Pyroptosis in the kidney.","volume":"306","author":"Krautwald","year":"2014","journal-title":"Am J Physiol Renal Physiol"},{"key":"R148-6-20230306","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1128\/IAI.01382-08","article-title":"Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila.","volume":"77","author":"Case","year":"2009","journal-title":"Infect Immun"},{"key":"R149-6-20230306","doi-asserted-by":"crossref","first-page":"12419","DOI":"10.1073\/pnas.1019041108","article-title":"Listeria monocytogenes engineered to activate the Nlrc4 inflammasome are severely attenuated and are poor inducers of protective immunity.","volume":"108","author":"Sauer","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R150-6-20230306","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1038\/ni.1960","article-title":"Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.","volume":"11","author":"Miao","year":"2010","journal-title":"Nat Immunol"},{"key":"R151-6-20230306","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nature10558","article-title":"Non-canonical inflammasome activation targets caspase-11.","volume":"479","author":"Kayagaki","year":"2011","journal-title":"Nature"},{"key":"R152-6-20230306","doi-asserted-by":"crossref","first-page":"19997","DOI":"10.1074\/jbc.M110.122127","article-title":"Effective blockage of both the extrinsic and intrinsic pathways of apoptosis in mice by TAT-crmA.","volume":"285","author":"Krautwald","year":"2010","journal-title":"J Biol Chem"},{"key":"R153-6-20230306","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1038\/nature05859","article-title":"RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels.","volume":"447","author":"Yagoda","year":"2007","journal-title":"Nature"},{"key":"R154-6-20230306","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.cell.2013.12.010","article-title":"Regulation of ferroptotic cancer cell death by GPX4.","volume":"156","author":"Yang","year":"2014","journal-title":"Cell"},{"key":"R155-6-20230306","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: An iron-dependent form of nonapoptotic cell death.","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"key":"R156-6-20230306","doi-asserted-by":"crossref","first-page":"4551","DOI":"10.1021\/ja411006a","article-title":"Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models.","volume":"136","author":"Skouta","year":"2014","journal-title":"J Am Chem Soc"},{"key":"R157-6-20230306","doi-asserted-by":"crossref","first-page":"4423","DOI":"10.1172\/JCI67867","article-title":"Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury.","volume":"123","author":"Zarjou","year":"2013","journal-title":"J Clin Invest"},{"key":"R158-6-20230306","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/nchembio.1416","article-title":"The role of iron and reactive oxygen species in cell death.","volume":"10","author":"Dixon","year":"2014","journal-title":"Nat Chem Biol"},{"key":"R159-6-20230306","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1681\/ASN.2013030281","article-title":"Tubular von Hippel-Lindau knockout protects against rhabdomyolysis-induced AKI.","volume":"24","author":"F\u00e4hling","year":"2013","journal-title":"J Am Soc Nephrol"},{"key":"R160-6-20230306","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nature13147","article-title":"Unexpected link between an antibiotic, pannexin channels and apoptosis.","volume":"507","author":"Poon","year":"2014","journal-title":"Nature"},{"key":"R161-6-20230306","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/nature11714","article-title":"Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation.","volume":"493","author":"Juncadella","year":"2013","journal-title":"Nature"},{"key":"R162-6-20230306","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1038\/nature08296","article-title":"Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance.","volume":"461","author":"Elliott","year":"2009","journal-title":"Nature"},{"key":"R163-6-20230306","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1038\/cdd.2009.184","article-title":"Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features.","volume":"17","author":"Vanden Berghe","year":"2010","journal-title":"Cell Death Differ"},{"key":"R164-6-20230306","doi-asserted-by":"crossref","first-page":"6566","DOI":"10.1073\/pnas.1201608109","article-title":"Bax regulates primary necrosis through mitochondrial dynamics.","volume":"109","author":"Whelan","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R165-6-20230306","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1126\/science.1249361","article-title":"Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis.","volume":"343","author":"Newton","year":"2014","journal-title":"Science"},{"key":"R166-6-20230306","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1038\/cdd.2013.94","article-title":"RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1\/2 depletion or TAK1 kinase inhibition.","volume":"20","author":"Dondelinger","year":"2013","journal-title":"Cell Death Differ"},{"key":"R167-6-20230306","doi-asserted-by":"crossref","first-page":"e1004","DOI":"10.1038\/cddis.2013.531","article-title":"Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis.","volume":"5","author":"Remijsen","year":"2014","journal-title":"Cell Death Dis"},{"key":"R168-6-20230306","doi-asserted-by":"crossref","first-page":"32608","DOI":"10.1074\/jbc.273.49.32608","article-title":"Inhibition of human caspases by peptide-based and macromolecular inhibitors.","volume":"273","author":"Garcia-Calvo","year":"1998","journal-title":"J Biol Chem"},{"key":"R170-6-20230306","doi-asserted-by":"crossref","first-page":"F1239","DOI":"10.1152\/ajprenal.00659.2011","article-title":"zVAD-fmk prevents cisplatin-induced cleavage of autophagy proteins but impairs autophagic flux and worsens renal function.","volume":"303","author":"Herzog","year":"2012","journal-title":"Am J Physiol Renal Physiol"},{"key":"R171-6-20230306","doi-asserted-by":"crossref","first-page":"3455","DOI":"10.1038\/ncomms4455","article-title":"Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.","volume":"5","author":"Josefsson","year":"2014","journal-title":"Nat Commun"},{"key":"R172-6-20230306","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/nchembio711","article-title":"Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.","volume":"1","author":"Degterev","year":"2005","journal-title":"Nat Chem Biol"},{"key":"R173-6-20230306","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.celrep.2013.08.045","article-title":"Protective roles for caspase-8 and cFLIP in adult homeostasis.","volume":"5","author":"Weinlich","year":"2013","journal-title":"Cell Reports"},{"key":"R174-6-20230306","doi-asserted-by":"crossref","first-page":"3412","DOI":"10.1093\/ndt\/gfs373","article-title":"Programmed necrosis in acute kidney injury.","volume":"27","author":"Linkermann","year":"2012","journal-title":"Nephrol Dial Transplant"}],"container-title":["Journal of the American Society of Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00001751-201412000-00006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T19:24:28Z","timestamp":1786130668000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00001751-201412000-00006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":171,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1681\/asn.2014030262","relation":{},"ISSN":["1046-6673"],"issn-type":[{"value":"1046-6673","type":"print"}],"subject":[],"published":{"date-parts":[[2014,12]]}}}