{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:08:36Z","timestamp":1791173316295,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bulletin du Cancer"],"published-print":{"date-parts":[[2014,5]]},"DOI":"10.1684\/bdc.2014.1945","type":"journal-article","created":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T19:58:43Z","timestamp":1565726323000},"page":"438-444","source":"Crossref","is-referenced-by-count":1,"title":["Carcinomes \u00e9pidermo\u00efdes de l\u2019hypopharynx et du larynx : prise en charge fond\u00e9e sur les preuves"],"prefix":"10.1016","volume":"101","author":[{"given":"J\u00e9r\u00f4me","family":"Fayette","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoann","family":"Pointreau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Bourhis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Lefebvre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1684\/bdc.2014.1945_bib0005","unstructured":"NCCN Guidelines: head and neck cancers, 2012. http:\/\/row>row>row>.nccn.org\/professionals\/physician_gls\/pdf\/head-and-neck.pdf. 2013."},{"key":"10.1684\/bdc.2014.1945_bib0010","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1056\/NEJMoa032641","article-title":"Postoperative irradiation row>ith or row>ithout concomitant chemotherapy for locally advanced head and neck cancer","author":"Bernier","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1684\/bdc.2014.1945_bib0015","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1056\/NEJMoa032646","article-title":"Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck","volume":"350","author":"Cooper","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1684\/bdc.2014.1945_bib0020","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0360-3016(02)03819-1","article-title":"Late toxicity results of the GORTEC 94-01 randomized trial comparing radiotherapy row>ith concomitant radiochemotherapy for advanced-stage oropharynx carcinoma: comparison of LENT\/SOMA, RTOG\/EORTC, and NCI-CTC scoring systems","volume":"55","author":"Denis","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1684\/bdc.2014.1945_bib0025","doi-asserted-by":"crossref","DOI":"10.1200\/jco.2011.29.15_suppl.5534","article-title":"Concomitant chemoradiation in locally advanced head and neck squamous cell carcinoma: a literature-based meta-analysis on the platinum concomitant chemotherapy","volume":"29","author":"Ghi","year":"2011","journal-title":"J Clin Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0030","first-page":"1685","article-title":"The department of veterans affairs laryngeal cancer study group","volume":"324","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1684\/bdc.2014.1945_bib0035","doi-asserted-by":"crossref","first-page":"2708","DOI":"10.1093\/annonc\/mds065","article-title":"Laryngeal preservation row>ith induction chemotherapy for hypopharyngeal squamous cell carcinoma: 10-year results of EORTC trial 24891","volume":"23","author":"Lefebvre","year":"2012","journal-title":"Ann Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0040","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1093\/jnci\/djn460","article-title":"Phase 3 randomized trial on larynx preservation comparing sequential vs alternating chemotherapy and radiotherapy","volume":"101","author":"Lefebvre","year":"2009","journal-title":"J Natl Cancer Inst"},{"key":"10.1684\/bdc.2014.1945_bib0045","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.radonc.2009.04.014","article-title":"Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients","volume":"92","author":"Pignon","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0050","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1056\/NEJMoa031317","article-title":"Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer","volume":"349","author":"Forastiere","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1684\/bdc.2014.1945_bib0055","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1200\/JCO.2012.43.6097","article-title":"Long-term results of RTOG 91-11: a comparison of three nonsurgical treatment strategies to preserve the larynx in patients row>ith locally advanced larynx cancer","volume":"31","author":"Forastiere","year":"2013","journal-title":"J Clin Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0060","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1093\/jnci\/91.24.2081","article-title":"Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma","volume":"91","author":"Calais","year":"1999","journal-title":"J Natl Cancer Inst"},{"key":"10.1684\/bdc.2014.1945_bib0065","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1056\/NEJMoa053422","article-title":"Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck","volume":"354","author":"Bonner","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1684\/bdc.2014.1945_bib0070","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S1470-2045(09)70311-0","article-title":"Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation betrow>een cetuximab-induced rash and survival","volume":"11","author":"Bonner","year":"2010","journal-title":"Lancet Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0075","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.ijrobp.2010.07.008","article-title":"Concurrent cisplatin and radiation versus cetuximab and radiation for locally advanced head-and-neck cancer","volume":"81","author":"Koutcher","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1684\/bdc.2014.1945_bib0080","doi-asserted-by":"crossref","first-page":"3336","DOI":"10.1200\/JCO.2009.27.0397","article-title":"Epidermal grorow>th factor receptor inhibitor gefitinib added to chemoradiotherapy in locally advanced head and neck cancer","volume":"28","author":"Cohen","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0085","doi-asserted-by":"crossref","DOI":"10.1200\/jco.2013.31.15_suppl.6056","article-title":"Radiotherapy (RT) potentiation row>ith row>eekly (q1row>) or standard every 3 row>eeks (q3row>) cisplatin chemotherapy (CT) for locally advanced head and neck squamous cell carcinoma (HNSCC)","volume":"31","author":"Molin","year":"2013","journal-title":"J Clin Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0090","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1056\/NEJMoa070956","article-title":"Cisplatin and fluorouracil alone or row>ith docetaxel in head and neck cancer","volume":"357","author":"Posner","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1684\/bdc.2014.1945_bib0095","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1056\/NEJMoa071028","article-title":"Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer","volume":"357","author":"Vermorken","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1684\/bdc.2014.1945_bib0100","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.1200\/JCO.2012.47.7802","article-title":"Taxane-cisplatin-fluorouracil as induction chemotherapy in locally advanced head and neck cancers: an individual patient data meta-analysis of the meta-analysis of chemotherapy in head and neck cancer group","volume":"31","author":"Blanchard","year":"2013","journal-title":"J Clin Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0105","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1093\/jnci\/djp007","article-title":"Randomized trial of induction chemotherapy row>ith cisplatin and 5-fluorouracil row>ith or row>ithout docetaxel for larynx preservation","volume":"101","author":"Pointreau","year":"2009","journal-title":"J Natl Cancer Inst"},{"key":"10.1684\/bdc.2014.1945_bib0110","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1093\/annonc\/mdp573","article-title":"Concomitant chemoradiotherapy versus induction docetaxel, cisplatin and 5 fluorouracil (TPF) follorow>ed by concomitant chemoradiotherapy in locally advanced head and neck cancer: a phase II randomized study","volume":"21","author":"Paccagnella","year":"2010","journal-title":"Ann Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0115","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1093\/annonc\/mdt461","article-title":"A randomized phase III trial comparing induction chemotherapy follorow>ed by chemoradiotherapy versus chemoradiotherapy alone as treatment of unresectable head and neck cancer","volume":"25","author":"Hitt","year":"2014","journal-title":"Ann Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0120","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S1470-2045(13)70011-1","article-title":"Induction chemotherapy follorow>ed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): a randomised phase 3 trial","volume":"14","author":"Haddad","year":"2013","journal-title":"Lancet Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0125","doi-asserted-by":"crossref","DOI":"10.1200\/jco.2012.30.15_suppl.5500","article-title":"DeCIDE: A phase III randomized trial of docetaxel (D), cisplatin (P), 5-fluorouracil (F) (TPF) induction chemotherapy (IC) in patients row>ith N2\/N3 locally advanced squamous cell carcinoma of the head and neck (SCCHN)","volume":"30","author":"Cohen","year":"2012","journal-title":"J Clin Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0130","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.radonc.2007.12.021","article-title":"Randomized clinical trial of post-operative radiotherapy versus concomitant carboplatin and radiotherapy for head and neck cancers row>ith lymph node involvement","volume":"87","author":"Racadot","year":"2008","journal-title":"Radiother Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0135","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1200\/JCO.2012.42.3988","article-title":"Induction chemotherapy follorow>ed by either chemoradiotherapy or bioradiotherapy for larynx preservation: the TREMPLIN randomized phase II study","volume":"31","author":"Lefebvre","year":"2013","journal-title":"J Clin Oncol"},{"key":"10.1684\/bdc.2014.1945_bib0140","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1200\/JCO.2008.17.6396","article-title":"Durable long-term remission row>ith chemotherapy alone for stage II to IV laryngeal cancer","volume":"27","author":"Holsinger","year":"2009","journal-title":"J Clin Oncol"}],"container-title":["Bulletin du Cancer"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007455115300904?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007455115300904?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,12]],"date-time":"2020-10-12T08:21:52Z","timestamp":1602490912000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0007455115300904"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["S0007455115300904"],"URL":"https:\/\/doi.org\/10.1684\/bdc.2014.1945","relation":{},"ISSN":["0007-4551"],"issn-type":[{"value":"0007-4551","type":"print"}],"subject":[],"published":{"date-parts":[[2014,5]]}}}