{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:59:56Z","timestamp":1790675996956,"version":"4.1.0"},"reference-count":52,"publisher":"Tech Science Press","issue":"1","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Cytokine Netw"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1684\/ecn.2019.0421","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T17:43:44Z","timestamp":1697823824000},"page":"15-22","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["IL-17, IL-10, IL-6, and IFN-\u03b3 in Egyptian Beh\u00e7et\u2019s disease: correlation with clinical manifestations"],"prefix":"10.32604","volume":"30","author":[{"given":"Roba M.","family":"Talaat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiba","family":"Sibaii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iman H.","family":"Bassyouni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amany","family":"El-Wakkad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"17807","published-online":{"date-parts":[[2019,5,27]]},"reference":[{"key":"421_CR1","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1007\/s13317-016-0074-1","volume":"7","author":"MJ Zeidan","year":"2016","unstructured":"Zeidan MJ, Saadoun D, Garrido M, Klatzmann D, Six A, Cacoub P. Beh\u00e7et\u2019s disease physiopathology: a contemporary review. Auto Immun Highlights 2016; 7: 4.","journal-title":"Auto Immun Highlights"},{"key":"421_CR2","doi-asserted-by":"crossref","unstructured":"Puccetti A, Pelosi A, Fiore FP, Patuzzo G, Lunardi C, Dolcino M. MicroRNA expression profiling in Beh\u00e7et\u2019s disease. J Immunol Res 2018; 2405150.","DOI":"10.1155\/2018\/2405150"},{"key":"421_CR3","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1007\/s13317-016-0074-1","volume":"7","author":"MJ Zeidan","year":"2016","unstructured":"Zeidan MJ, Saadoun D, Garrido M, Klatzmann D, Six A, Cacoub P. Beh\u00e7et\u2019s disease physiopathology: a contemporary review. Auto Immun Highlights 2016; 7: 4.","journal-title":"Auto Immun Highlights"},{"key":"421_CR4","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/s13052-017-0350-3","volume":"43","author":"R Gallizzi","year":"2017","unstructured":"Gallizzi R, De Vivo D, Valenti S, Pidone C, Romeo C, Caruso R, Claudio Romano R. Intestinal and neurological involvement in Beh\u00e7et disease: a clinical case. Ital J Pediatr 2017; 43: 33.","journal-title":"Ital J Pediatr"},{"key":"421_CR5","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1080\/030097402320318387","volume":"31","author":"K Hamzaoui","year":"2002","unstructured":"Hamzaoui K, Hamzaoui A, Guemira F, Bessioud M, Hamza M, Ayed K. Cytokine profile in Beh\u00e7et\u2019s disease patients. Relationship with disease activity. Scand J Rheumatol 2002; 31: 205.","journal-title":"Scand J Rheumatol"},{"key":"421_CR6","doi-asserted-by":"publisher","first-page":"297","DOI":"10.2492\/inflammregen.31.296","volume":"31","author":"J Shimizu","year":"2011","unstructured":"Shimizu J, Yoshikawa H, Takada E, Hirotsu C, Suzuki N. Unbalanced helper T cell function in Beh\u00e7et\u2019s disease. Inflamm Regen 2011; 31: 297.","journal-title":"Inflamm Regen"},{"key":"421_CR7","doi-asserted-by":"publisher","first-page":"49","DOI":"10.3390\/jcm6050049","volume":"6","author":"A Sadeghi","year":"2017","unstructured":"Sadeghi A, Davatchi F, Shahram F, Karimimoghadam A, Alikhani M, Pezeshgi A, Mazloomzadeh S, Sadeghi-Abdollahi B, Asadi-Khiavi M. Serum profiles of cytokines in Beh\u00e7et\u2019s disease. J Clin Med 2017; 6: 49.","journal-title":"J Clin Med"},{"key":"421_CR8","doi-asserted-by":"publisher","first-page":"52","DOI":"10.3109\/09273948.2016.1158276","volume":"25","author":"M Takeuchi","year":"2017","unstructured":"Takeuchi M, Karasawa Y, Harimoto K, Tanaka A, Shibata M, Sato T, Caspi RR, Ito M. Analysis of Th Cell-related cytokine production in Beh\u00e7et disease patients with uveitis before and after infliximab treatment. Ocul Immunol Inflamm 2017; 25: 52.","journal-title":"Ocul Immunol Inflamm"},{"key":"421_CR9","first-page":"880","volume":"19","author":"W Chi","year":"2010","unstructured":"Chi W, Yang P, Zhu X, et al. Production of interleukin-17 in Beh\u00e7et\u2019s disease is inhibited by cyclosporin A. Mol Vis 2010; 19: 880.","journal-title":"Mol Vis"},{"key":"421_CR10","first-page":"393","volume":"47","author":"L Liang","year":"2011","unstructured":"Liang L, Wang H, Peng XY, Zhao M. The changes of Thelper lymphocyte subsets in patients with Beh\u00e7et\u2019s disease. Zhonghua YanKe ZaZhi 2011; 47: 393.","journal-title":"Zhonghua YanKe ZaZhi"},{"key":"421_CR11","doi-asserted-by":"crossref","unstructured":"Sugita S, Kawazoe Y, Imai A, Yamada Y, Horie S, Mochizuki M. Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Beh\u00e7et\u2019s disease. Arthritis Res Ther 2012; 14.","DOI":"10.1186\/ar3824"},{"key":"421_CR12","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/s12929-017-0317-0","volume":"24","author":"CF Lin","year":"2017","unstructured":"Lin CF, Lin CM, Lee KY, Wu SY, Feng PH, Chen KYHC, Chen CL, Wang YC, Tseng PC, Tsai TT. Escape from IFN-\u03b3-dependent immunosurveillance in tumorigenesis. J Biomed Sci 2017; 24: 10.","journal-title":"J Biomed Sci"},{"key":"421_CR13","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1186\/ar432","volume":"4","author":"EF Rosloniec","year":"2002","unstructured":"Rosloniec EF, Latham K, Guedez YB. Paradoxical role of IFN-\u03b3 in models of Th1-mediated autoimmunity. Arthritis Res 2002; 4: 333.","journal-title":"Arthritis Res"},{"key":"421_CR14","doi-asserted-by":"publisher","first-page":"566","DOI":"10.4049\/jimmunol.177.1.566","volume":"177","author":"Y Komiyama","year":"2006","unstructured":"Komiyama Y, Nakae S, Matsuki T, Nambu A, Ishigame H, Kakuta S, Sudo K, Iwakura Y. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J Immunol 2006; 177: 566.","journal-title":"J Immunol"},{"key":"421_CR15","doi-asserted-by":"publisher","first-page":"275","DOI":"10.3389\/fimmu.2012.00275","volume":"3","author":"M Kubo","year":"2012","unstructured":"Kubo M, Motomura Y. Transcriptional regulation of the antiinflammatory cytokine IL-10 in acquired immune cells. Front Immunol 2012; 3: 275.","journal-title":"Front Immunol"},{"key":"421_CR16","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.1038\/ni1540","volume":"8","author":"DC Fitzgerald","year":"2007","unstructured":"Fitzgerald DC, Zhang GX, El-Behi M, et al. Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat Immunol 2007; 8: 1372.","journal-title":"Nat Immunol"},{"key":"421_CR17","doi-asserted-by":"publisher","first-page":"5771","DOI":"10.4049\/jimmunol.180.9.5771","volume":"180","author":"KN Couper","year":"2008","unstructured":"Couper KN, Blount DG, Riley EM. IL-10: the master regulator of immunity to infection. J Immunol 2008; 180: 5771.","journal-title":"J Immunol"},{"key":"421_CR18","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1038\/82707","volume":"6","author":"T Mosmann","year":"2000","unstructured":"Mosmann T. Complexity or coherence? Cytokine secretion by B cells. Nat Immunol 2000; 6: 465.","journal-title":"Nat Immunol"},{"key":"421_CR19","doi-asserted-by":"publisher","first-page":"29752","DOI":"10.1074\/jbc.M300489200","volume":"278","author":"CR Yu","year":"2003","unstructured":"Yu CR, Mahdi RM, Ebong S, Vistica BP, Gery I, Egwuagu CE. Suppressor of cytokine signaling 3 regulates proliferation and activation of T-helper cells. J Biol Chem 2003; 278: 29752.","journal-title":"J Biol Chem"},{"key":"421_CR20","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1016\/j.lfs.2012.03.017","volume":"90","author":"ES Kim","year":"2012","unstructured":"Kim ES, Kim SW, Moon CM, et al. Interactions between IL17A, IL23R, and STAT4 polymorphisms confer susceptibility to intestinal Beh\u00e7et\u2019s disease in Korean population. Life Sci 2012; 90: 740.","journal-title":"Life Sci"},{"key":"421_CR21","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1038\/nature04753","volume":"441","author":"E Bettelli","year":"2006","unstructured":"Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006; 441: 235\u20138.","journal-title":"Nature"},{"key":"421_CR22","doi-asserted-by":"crossref","first-page":"596","DOI":"10.47102\/annals-acadmedsg.V33N5p596","volume":"33","author":"N Akdeniz","year":"2004","unstructured":"Akdeniz N, Esrefoglu M, Keles MS, Karakuzu A, Atasoy M. Serum interleukin-2, interleukin-6, tumour necrosis factor-alpha and nitric oxide levels in patients with Beh\u00e7et\u2019s disease. Ann Acad Med Singapore 2004; 33: 596\u20139.","journal-title":"Ann Acad Med Singapore"},{"issue":"8697","key":"421_CR23","first-page":"1078","volume":"335","author":"International Study Group for Beh\u00e7et\u2019s Disease","year":"1990","unstructured":"International Study Group for Beh\u00e7et\u2019s Disease. Criteria for diagnosis of Beh\u00e7et\u2019s disease. Lancet 1990; 335(8697):1078.","journal-title":"Lancet"},{"key":"421_CR24","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1007\/BF00262712","volume":"15","author":"AO Aydintug","year":"1995","unstructured":"Aydintug AO, Tokg\u00f6z G, \u00d6zoran K, D\u00fczg\u00fcn N, G\u00fcrler A, Tutkak H. Elevated levels of soluble intercellular adhesion molecule-1 correlate with disease activity in Beh\u00e7et\u2019s disease. Rheumatol Int 1995; 15: 75.","journal-title":"Rheumatol Int"},{"key":"421_CR25","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1007\/s00436-007-0478-y","volume":"101","author":"RM Talaat","year":"2007","unstructured":"Talaat RM, El-Bassiouny AI, Osman AM, Yossif M, Charmy R, Al-Sherbiny MM. Cytokine secretion profile associated with periportal fibrosis in S. mansoni infected Egyptian patients. Parasitol Res 2007; 101: 289.","journal-title":"Parasitol Res"},{"key":"421_CR26","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1089\/vim.2009.0089","volume":"23","author":"RM Talaat","year":"2010","unstructured":"Talaat RM. Soluble angiogenesis factors in sera of Egyptian patients with hepatitis C virus infection: correlation with disease severity. Viral Immunol 2010; 23: 151.","journal-title":"Viral Immunol"},{"key":"421_CR27","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1146\/annurev.immunol.25.022106.141557","volume":"25","author":"CT Weaver","year":"2007","unstructured":"Weaver CT, Hatton RD, Mangan PR, Harrington LE. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol 2007; 25: 821.","journal-title":"Annu Rev Immunol"},{"key":"421_CR28","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1016\/j.autrev.2011.12.005","volume":"11","author":"ZY Zhou","year":"2012","unstructured":"Zhou ZY, Chen SL, Shen N, Lu Y. Cytokines and Beh\u00e7et\u2019s disease. Autoimmun Rev 2012; 11: 699.","journal-title":"Autoimmun Rev"},{"key":"421_CR29","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1002\/jcla.21772","volume":"29","author":"ZM Akkurt","year":"2015","unstructured":"Akkurt ZM, Bozkurt M, Ucmak D, Uksel Y, Ucak H, Sula B, \u00d6zkurt GZ, Yildiz M, Akdeniz D, Arica M. Serum cytokine levels in Beh\u00e7et\u2019s disease. J Clin Lab Anal 2015; 29: 317.","journal-title":"J Clin Lab Anal"},{"key":"421_CR30","first-page":"1147","volume":"41","author":"Central Hirohata S","year":"2001","unstructured":"Central Hirohata S. Nervous system involvement in Beh\u00e7ets disease. RinshoShinkeigazu 2001; 41: 1147.","journal-title":"RinshoShinkeigazu"},{"key":"421_CR31","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/s00403-007-0794-1","volume":"300","author":"A Akman","year":"2008","unstructured":"Akman A, Ekinsi NC, Kacaroglu H, et al. Relationship between Turkish patients and Beh\u00e7et\u2019s disease. Arch Dermatol Res 2008; 300: 19.","journal-title":"Arch Dermatol Res"},{"key":"421_CR32","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1093\/rheumatology\/keh195","volume":"43","author":"S Koarada","year":"2004","unstructured":"Koarada S, Haruta Y, Tada Y, et al. Increased entry of CD4+ T cells into the Th1 cytokine effector pathway during T-cell division following stimulation in Beh\u00e7et\u2019s disease. Rheumatology (Oxford) 2004; 43: 843.","journal-title":"Rheumatology (Oxford)"},{"key":"421_CR33","first-page":"551","volume":"109","author":"S Nalbant","year":"2008","unstructured":"Nalbant S, Sahan B, Durna M, et al. Cytokine profile in Beh\u00e7et uveitis. Bratisl Lek Listy 2008; 109: 551.","journal-title":"Bratisl Lek Listy"},{"issue":"Suppl.2","key":"421_CR34","first-page":"S1","volume":"2","author":"E Choy","year":"2017","unstructured":"Choy E, Rose-John S. Interleukin-6 as a multifunctional regulator: inflammation, immune response, and fibrosis. J Scleroderma Relat Disord 2017; 2(Suppl. 2):S1\u20135.","journal-title":"J Scleroderma Relat Disord"},{"key":"421_CR35","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/S0167-4889(02)00325-7","volume":"1592","author":"KJ Kallen","year":"2002","unstructured":"Kallen KJ. The role of transsignalling via the agonistic soluble IL-6 receptor in human diseases. Biochim Biophys Acta 2002; 1592: 323.","journal-title":"Biochim Biophys Acta"},{"key":"421_CR36","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/j.autrev.2011.11.026","volume":"11","author":"M Pineton de Chambrun","year":"2012","unstructured":"Pineton de Chambrun M, Wechsler B, Geri G, Cacoub P, Saadoun D. New insights into the pathogenesis of Beh\u00e7et\u2019s disease. Autoimmun Rev 2012; 11: 687.","journal-title":"Autoimmun Rev"},{"key":"421_CR37","unstructured":"Fessler JB. Vasculitis and related diseases. In: Koopman WJ, Moreland LW, (eds). Arthritis and allied conditions. Philadelphia, Pa, USA: Lippincott Williams and Wilkins;1835\u201344."},{"key":"421_CR38","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1111\/j.1756-185X.2009.01419.x","volume":"12","author":"F Frikha","year":"2009","unstructured":"Frikha F, Marzouk S, Kaddour N, Frigui M, Bahloul Z. Destructive arthritis in Beh\u00e7et\u2019s disease: a report of eight cases and literature review. Int J Rheum Dis 2009; 12: 250.","journal-title":"Int J Rheum Dis"},{"key":"421_CR39","doi-asserted-by":"publisher","first-page":"298","DOI":"10.3109\/s10165-011-0497-5","volume":"22","author":"T Hirano","year":"2012","unstructured":"Hirano T, Ohguro N, Hohki S, et al. A case of Beh\u00e7et\u2019s disease treated with a humanized anti-interleukin-6 receptor antibody, tocilizumab. Mod Rheumatol 2012; 22: 298.","journal-title":"Mod Rheumatol"},{"key":"421_CR40","doi-asserted-by":"publisher","first-page":"2291","DOI":"10.1002\/art.20334","volume":"50","author":"M Ben Ahmed","year":"2004","unstructured":"Ben Ahmed M, Houman H, Miled M, Dellagi K, Louzir H. Involvement of chemokines and Th1 cytokines in the pathogenesis of mucocutaneous lesions of Beh\u00e7et\u2019s disease. Arthritis Rheum 2004; 50: 2291.","journal-title":"Arthritis Rheum"},{"key":"421_CR41","first-page":"1425","volume":"17","author":"S Jiang","year":"2011","unstructured":"Jiang S, Liu X, Luo L, et al. Serum levels of Th17-related cytokines in Beh\u00e7et disease patients after cataract surgery. Mol Vis 2011; 17: 1425.","journal-title":"Mol Vis"},{"key":"421_CR42","first-page":"123","volume":"16","author":"KM Pollard","year":"2013","unstructured":"Pollard KM, Cauvi DM, Toomey CB, Morris KV, Kono DH. Interferon-\u03b3 and systemic autoimmunity. Discov Med 2013; 16: 123.","journal-title":"Discov Med"},{"key":"421_CR43","unstructured":"Ramya S, Gaddam S. Cytokines that mediate and regulate immune responses; 2015. http:\/\/austinpublishinggroup.com\/ebooks\/innovative-immunology\/chapters\/II-14-05.pdf (innovative immunology, ISBN: 978-0-9971499-1-3)."},{"key":"421_CR44","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1172\/JCI31860","volume":"117","author":"J Zhang","year":"2007","unstructured":"Zhang J. Yin and yang interplay of IFN-\u03b3 in inflammation and autoimmune disease. J Clin Investig 2007; 117: 871\u20133.","journal-title":"J Clin Investig"},{"key":"421_CR45","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1089\/jir.2010.0148","volume":"21","author":"H Belguendouz","year":"2011","unstructured":"Belguendouz H, Messaoudene D, Lahmar K, et al. Interferongamma and nitric oxide production during Beh\u00e7et uveitis. immunomodulatory effect of IL-10. J Interferon Cytokine Res 2011; 21: 643\u201351.","journal-title":"J Interferon Cytokine Res"},{"key":"421_CR46","doi-asserted-by":"publisher","first-page":"105","DOI":"10.3129\/i07-179","volume":"43","author":"F Ilhan","year":"2008","unstructured":"Ilhan F, Demir T, T\u00fcrk\u00e7\u00fcoglu P, Turgut B, Demir N, G\u00f6dekmerdan A. Th1 polarization of the immune response in uveitis in Beh\u00e7et\u2019s disease. Can J Ophthalmol 2008; 43: 105.","journal-title":"Can J Ophthalmol"},{"key":"421_CR47","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1177\/112067210901900616","volume":"19","author":"Y Ozdamar","year":"2009","unstructured":"Ozdamar Y, Berker N, Bahar G, et al. Inflammatory mediators and posterior segment involvement in ocular Beh\u00e7et disease. Eur J Ophthalmol 2009; 19: 998.","journal-title":"Eur J Ophthalmol"},{"key":"421_CR48","doi-asserted-by":"publisher","first-page":"227","DOI":"10.12659\/MSM.881720","volume":"17","author":"K Hamzaoui","year":"2011","unstructured":"Hamzaoui K, Bouali E, Ghorbel I, Khanfir M, Houman H, Hamzaoui A. Expression of Th17 and RORyt mRNA in Beh\u00e7et\u2019s disease. Med Sci Monit 2011; 17: 227.","journal-title":"Med Sci Monit"},{"key":"421_CR49","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1038\/nature07240","volume":"455","author":"K Atarashi","year":"2008","unstructured":"Atarashi K, Nishimura J, Shima T, Umesaki Y, Yamamoto M, Onoue M, Yagita H, Ishii N, Evans R, Honda K, Takeda K. ATP drives lamina propria TH17 cell differentiation. Nature 2008; 455: 808.","journal-title":"Nature"},{"key":"421_CR50","doi-asserted-by":"publisher","first-page":"400","DOI":"10.4172\/2155-9899.1000400","volume":"7","author":"B Guo","year":"2016","unstructured":"Guo B. IL-10 modulates Th17 pathogenicity during autoimmune diseases. J Clin Cell Immunol 2016; 7: 400.","journal-title":"J Clin Cell Immunol"},{"key":"421_CR51","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1111\/j.1346-8138.2003.tb00442.x","volume":"30","author":"BC Aridogan","year":"2003","unstructured":"Aridogan BC, Yildirim M, Baysal V, Inaloz HS, Baz K, Kaya S. Serum levels of IL-4, IL-10, IL-12, IL-13 and IFN-gamma in Beh\u00e7et\u2019s disease. J Dermatol 2003; 30: 602.","journal-title":"J Dermatol"},{"issue":"11\u201312","key":"421_CR52","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1007\/s10528-013-9621-x","volume":"51","author":"L Vaccarino","year":"2013","unstructured":"Vaccarino L, Triolo G, Palombo AA, Scola L, Palmeri M, Bova M, Candore G, Lio D, Balistreri CR. Pathological implications of Th1\/Th2 cytokine genetic variants in Beh\u00e7et\u2019s disease: data from a pilot study in a Sicilian population. Biochem Genet 2013; 51(11\u201312):967\u201375. doi: https:\/\/doi.org\/10.1007\/s10528-013-9621-x.","journal-title":"Biochem Genet"}],"container-title":["European Cytokine Network"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1684\/ecn.2019.0421.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1684\/ecn.2019.0421\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1684\/ecn.2019.0421.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/www.jle.com\/10.1684\/ecn.2019.0421","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:27:35Z","timestamp":1790674055000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.techscience.com\/ECN\/v30n1\/65398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":52,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["421"],"URL":"https:\/\/doi.org\/10.1684\/ecn.2019.0421","relation":{},"ISSN":["1952-4005"],"issn-type":[{"value":"1952-4005","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"17 Januar 2019","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 Mai 2019","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}